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公开(公告)号：US11921095B2
公开(公告)日：2024-03-05
申请号：US17069477
申请日：2020-10-13
Applicant: Micromass UK Limited
Inventor： Gareth Rhys Jones , Michael McCullagh , Alastair Murray Booth
CPC classification number: G01N30/88 , G01N30/8675 , H01J49/0027 , H01J49/0031 , H01J49/0036 , G01N2030/8804 , G01N2030/889 , H01J49/0454
Abstract: A method of mass spectrometry is disclosed comprising repeatedly or continuously causing first analyte sample to be released or ejected from a first sample. A determination is made as to whether or not a quality threshold such as an intensity threshold has been met or exceeded, wherein if the quality threshold has been met or exceeded then the method further comprises repeatedly or continuously causing second analyte sample to be released or ejected from a second sample.
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公开(公告)号：US20210109069A1
公开(公告)日：2021-04-15
申请号：US17069477
申请日：2020-10-13
Applicant: Micromass UK Limited
Inventor： Gareth Rhys Jones , Michael McCullagh , Alastair Murray Booth
Abstract: A method of mass spectrometry is disclosed comprising repeatedly or continuously causing first analyte sample to be released or ejected from a first sample. A determination is made as to whether or not a quality threshold such as an intensity threshold has been met or exceeded, wherein if the quality threshold has been met or exceeded then the method further comprises repeatedly or continuously causing second analyte sample to be released or ejected from a second sample.
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公开(公告)号：US09947524B2
公开(公告)日：2018-04-17
申请号：US14727941
申请日：2015-06-02
Applicant: Micromass UK Limited
Inventor： Steven Derek Pringle , Michael Raymond Morris , Stephen Smith , Michael McCullagh
IPC: H01J49/16 , H01J49/00 , H01J49/10 , H01J49/04 , H01J49/06 , A61B17/32 , A61B17/3203 , A61B18/00 , A61B18/14 , A61B18/18
CPC classification number: H01J49/16 , A61B17/320068 , A61B17/3203 , A61B18/14 , A61B2018/00994 , A61B2018/1412 , A61B2018/1807 , A61B2218/008 , H01J49/0022 , H01J49/0031 , H01J49/04 , H01J49/0459 , H01J49/049 , H01J49/06 , H01J49/10
Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analyzed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporizes a portion of the substrate. The vapor is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionized to form analyte ions which are then mass analyzed.
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公开(公告)号：US20180233345A1
公开(公告)日：2018-08-16
申请号：US15953810
申请日：2018-04-16
Applicant: MICROMASS UK LIMITED
Inventor： Steven Derek Pringle , Michael Raymond Morris , Stephen Smith , Michael McCullagh
CPC classification number: H01J49/16 , A61B17/3203 , A61B18/14 , A61B2017/32007 , A61B2018/00994 , A61B2018/1412 , A61B2018/1807 , A61B2218/008 , H01J49/0022 , H01J49/0031 , H01J49/04 , H01J49/0459 , H01J49/049 , H01J49/06 , H01J49/10
Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analysed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporises a portion of the substrate. The vapour is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionised to form analyte ions which are then mass analysed.
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Patent Agency Ranking
公开(公告)号：US20160054264A1
公开(公告)日：2016-02-25
申请号：US14783468
申请日：2014-04-15
Applicant: MICROMASS UK LIMITED
Inventor： Christopher Carver , David Eatough , Andrew Golding , Jeffrey Goshawk , Michael McCullagh
CPC classification number: G01N27/622 , H01J49/0031 , H01J49/0045 , H01J49/4215
Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.
Abstract translation: 公开了筛选至少一种目的化合物的样品的方法。 该方法包括将目的化合物的离子的离子迁移率和至少一种其它物理化学性质与样品中候选离子的相同性质进行比较。 感兴趣的化合物的性质与样品中的候选离子的性质相匹配，然后可以测定样品以包含感兴趣的化合物。
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公开(公告)号：US09797866B2
公开(公告)日：2017-10-24
申请号：US14783468
申请日：2014-04-15
Applicant: Micromass UK Limited
Inventor： Christopher Carver , David Eatough , Andrew Golding , Jeffrey Goshawk , Michael McCullagh
CPC classification number: G01N27/622 , H01J49/0031 , H01J49/0045 , H01J49/4215
Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.
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公开(公告)号：US10317363B2
公开(公告)日：2019-06-11
申请号：US15790142
申请日：2017-10-23
Applicant: Micromass UK Limited
Inventor： Christopher Carver , David Eatough , Andrew Golding , Jeffrey Goshawk , Michael McCullagh
Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.
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公开(公告)号：US20180045679A1
公开(公告)日：2018-02-15
申请号：US15790142
申请日：2017-10-23
Applicant: Micromass UK Limited
Inventor： Christopher CARVER , David EATOUGH , Andrew GOLDING , Jeffrey Goshawk , Michael McCullagh
CPC classification number: G01N27/622 , H01J49/0031 , H01J49/0045 , H01J49/4215
Abstract: A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.
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公开(公告)号：US20150340215A1
公开(公告)日：2015-11-26
申请号：US14727941
申请日：2015-06-02
Applicant: Micromass UK Limited
Inventor： Steven Derek Pringle , Michael Raymond Morris , Stephen Smith , Michael McCullagh
CPC classification number: H01J49/16 , A61B17/320068 , A61B17/3203 , A61B18/14 , A61B2018/00994 , A61B2018/1412 , A61B2018/1807 , A61B2218/008 , H01J49/0022 , H01J49/0031 , H01J49/04 , H01J49/0459 , H01J49/049 , H01J49/06 , H01J49/10
Abstract: A method of detecting one or more compounds, chemicals or contaminants in a substrate by mass spectrometry is disclosed. A non-living substrate is analysed by contacting the substrate with a diathermy knife. An electric current is applied to the diathermy knife such that the diathermy knife vaporises a portion of the substrate. The vapour is aspirated via a sampling tube pumped by a venturi pump into a vacuum chamber of a mass spectrometer. Analyte molecules are aspirated into the vacuum chamber whereupon they impact a surface of the vacuum chamber and are ionised to form analyte ions which are then mass analysed.
Abstract translation: 公开了一种通过质谱法检测底物中的一种或多种化合物，化学物质或污染物的方法。 通过使基材与透热刀接触来分析非活性基材。 将电流施加到透热刀上，使得透热刀蒸发衬底的一部分。 通过由文丘里泵泵送到质谱仪的真空室中的取样管将蒸气吸入。 分析物分子被吸入真空室中，因此它们影响真空室的表面，并被电离以形成分析物离子，然后进行质量分析。
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