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1.发明授权Method for specifically detecting analyte using photocurrent, and electrode, measuring cell and measuring device for use therein 有权使用光电流专门检测分析物的方法，以及用于其中的电极，测量元件和测量装置公开(公告)号：US08092670B2
公开(公告)日：2012-01-10
申请号：US11992858
申请日：2006-09-28
申请人： Makoto Bekki , Hitoshi Ohara , Shuji Sonezaki , Koki Kanehira , Yumi Ogami , Hiroshi Ishikawa , Yumi Osaki , Hiromasa Tokudome , Yoko Yamada , Masahiro Miyauchi
发明人： Makoto Bekki , Hitoshi Ohara , Shuji Sonezaki , Koki Kanehira , Yumi Ogami , Hiroshi Ishikawa , Yumi Osaki , Hiromasa Tokudome , Yoko Yamada , Masahiro Miyauchi
IPC分类号： G01N27/26 , G01N33/48 , G01N33/487 , G01N33/49 , G01N33/493 , G01N33/50 , G01N33/53 , G01N33/533
CPC分类号： G01N33/5438
摘要： A method, an electrode, a measuring cell, and a measuring device are disclosed which can detect and quantitatively determine an analyte having specific bonding properties, in a highly sensitive, simple and accurate manner using photocurrent. This method comprises contacting a working electrode and a counter electrode with an electrolyte medium, wherein the working electrode has an analyte immobilized thereon through a probe substance and wherein the analyte is bonded to a sensitizing dye; irradiating the working electrode with light to photoexcite the sensitizing dye; and detecting photocurrent flowing between the working electrode and the counter electrode, wherein the photocurrent is generated by transfer of electrons from the photoexcited sensitizing dye to the working electrode. The working electrode comprises an electron accepting layer comprising an electron accepting substance capable of accepting electrons released from the sensitizing dye in response to photoexcitation, wherein the probe substance is supported on a surface of the electron accepting layer. The electron accepting substance is an oxide semiconductor having an energy level lower than that of a lowest unoccupied molecular orbit (LUMO) of the sensitizing dye. The electrolyte medium comprises an electrolyte and at least one solvent selected from an aprotic solvent and a protic solvent, wherein the electrolyte comprises a salt capable of providing an oxidized sensitizing dye with electrons.
摘要翻译： 公开了一种方法，电极，测量单元和测量装置，其可以使用光电流以高灵敏度，简单和准确的方式检测和定量地确定具有特定粘合特性的分析物。 该方法包括使工作电极和对电极与电解质介质接触，其中工作电极通过探针物质固定在其上的分析物，并且其中分析物与致敏染料结合; 用光照射工作电极对光敏染料进行光刺激; 并且检测在工作电极和对电极之间流动的光电流，其中通过将电子从光激发敏化染料转移到工作电极而产生光电流。 工作电极包括电子接受层，其包含能够响应于光激发而接受从感光染料释放的电子的电子接受物质，其中探针物质被负载在电子接受层的表面上。 电子接受物质是具有比敏化染料的最低未占据分子轨道（LUMO）的能级更低的氧化物半导体。 电解质介质包括电解质和至少一种选自非质子溶剂和质子溶剂的溶剂，其中电解质包含能够提供氧化的致敏染料与电子的盐。
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2.发明申请Method for Specifically Detecting Analyte Using Photocurrent, and Electrode, Measuring Cell and Measuring Device for Use Therein 有权使用光电流特异性检测分析物的方法，电极，测量单元及其使用的测量装置公开(公告)号：US20090294305A1
公开(公告)日：2009-12-03
申请号：US11992858
申请日：2006-09-28
申请人： Makoto Bekki , Hitoshi Ohara , Shuji Sonezaki , Koki Kanehira , Yumi Ogami , Hiroshi Ishikawa , Yumi Osaki , Hiromasa Tokudome , Yoko Yamada , Masahiro Miyauchi
发明人： Makoto Bekki , Hitoshi Ohara , Shuji Sonezaki , Koki Kanehira , Yumi Ogami , Hiroshi Ishikawa , Yumi Osaki , Hiromasa Tokudome , Yoko Yamada , Masahiro Miyauchi
CPC分类号： G01N33/5438
摘要： A method, an electrode, a measuring cell, and a measuring device are disclosed which can detect and quantitatively determine an analyte having specific bonding properties, in a highly sensitive, simple and accurate manner using photocurrent. This method comprises contacting a working electrode and a counter electrode with an electrolyte medium, wherein the working electrode has an analyte immobilized thereon through a probe substance and wherein the analyte is bonded to a sensitizing dye; irradiating the working electrode with light to photoexcite the sensitizing dye; and detecting photocurrent flowing between the working electrode and the counter electrode, wherein the photocurrent is generated by transfer of electrons from the photoexcited sensitizing dye to the working electrode. The working electrode comprises an electron accepting layer comprising an electron accepting substance capable of accepting electrons released from the sensitizing dye in response to photoexcitation, wherein the probe substance is supported on a surface of the electron accepting layer. The electron accepting substance is an oxide semiconductor having an energy level lower than that of a lowest unoccupied molecular orbit (LUMO) of the sensitizing dye. The electrolyte medium comprises an electrolyte and at least one solvent selected from an aprotic solvent and a protic solvent, wherein the electrolyte comprises a salt capable of providing an oxidized sensitizing dye with electrons.
摘要翻译： 公开了一种方法，电极，测量单元和测量装置，其可以使用光电流以高灵敏度，简单和准确的方式检测和定量地确定具有特定粘合特性的分析物。 该方法包括使工作电极和对电极与电解质介质接触，其中工作电极通过探针物质固定在其上的分析物，并且其中分析物与致敏染料结合; 用光照射工作电极对光敏染料进行光刺激; 并且检测在工作电极和对电极之间流动的光电流，其中通过将电子从光激发敏化染料转移到工作电极而产生光电流。 工作电极包括电子接受层，其包含能够响应于光激发而从感光染料中释放的电子的受电子物质，其中探针物质被负载在电子接受层的表面上。 电子接受物质是具有比敏化染料的最低未占据分子轨道（LUMO）的能级更低的氧化物半导体。 电解质介质包括电解质和至少一种选自非质子溶剂和质子溶剂的溶剂，其中电解质包含能够提供氧化的致敏染料与电子的盐。
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公开(公告)号：US08978411B2
公开(公告)日：2015-03-17
申请号：US12800979
申请日：2010-05-27
申请人： Atsushi Yamada , Seiji Inoue , Yoshio Miyata , Naoki Yokoyama , Etsuo Hasegawa , Jun Abei , Hiroshi Ishikawa , Aun Ota , Kouta Hagihara
发明人： Atsushi Yamada , Seiji Inoue , Yoshio Miyata , Naoki Yokoyama , Etsuo Hasegawa , Jun Abei , Hiroshi Ishikawa , Aun Ota , Kouta Hagihara
IPC分类号： F25B39/02 , F28D15/00 , F28D1/03 , F28D1/053 , F28D20/02 , F28F3/02 , F28F1/10 , F28F9/00 , F28F3/04 , F28F17/00 , F28D20/00 , F28D21/00
CPC分类号： F25D13/02 , F25B39/02 , F25D17/005 , F25D19/00 , F28D1/0333 , F28D1/05391 , F28D15/00 , F28D20/02 , F28D2020/0013 , F28D2021/0085 , F28F1/10 , F28F3/025 , F28F3/046 , F28F9/00 , F28F17/005 , Y02E60/145
摘要： An outer surface of a cold-storage container (or a refrigerant tube) is provided with a plurality of protrusion portions or recess portions. A cooling air passage, in which air flows to cool a space to be cooled in a cold storage time and in a cold release time of the cold storage material, is provided to contact a surface of the refrigerant tube on a side opposite to the cold storage container bonded to the refrigerant tube. The refrigerant tubes and the cold storage container form therebetween a cold-storage side air passage by the protrusion portions or the recess portions, such that air flows in the cold-storage side air passage separated from the cooling air passage. For example, the cold-storage side air passage is provided with a slanting space that causes condensed water or ice generated in the cold storage time to be drained along the cold-storage side air passage.
摘要翻译： 冷藏容器（或制冷剂管）的外表面设置有多个突出部或凹部。 提供冷却空气通道，其中空气流动以冷藏在冷藏时间和冷藏材料的冷却释放时间中待冷却的空间，以在制冷剂管的与冷的相反的一侧接触表面 储存容器与制冷剂管接合。 制冷剂管和冷藏容器通过突出部或凹部形成冷藏侧空气通路，使得空气在冷藏侧空气通路中与冷却风路分离。 例如，冷藏侧空气通道设置有倾斜空间，其使得在冷藏时间中产生的冷凝水或冰沿着冷藏侧空气通道排出。
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4.发明授权公开(公告)号：US08831304B2
公开(公告)日：2014-09-09
申请号：US13321301
申请日：2010-05-27
CPC分类号： G06T19/00 , A61B5/0066 , A61B5/0073 , A61B5/02007 , G01B9/02044 , G01B9/02083 , G01B9/02091 , G01N21/4795 , G06K9/0061 , G06K9/4609 , G06K2009/00932 , G06T7/11 , G06T7/143 , G06T2207/10101 , G06T2207/30101 , G06T2210/41
摘要： In the context of the early detection and monitoring of eye diseases, such as glaucoma and diabetic retinopathy, the use of optical coherence tomography presents the difficulty, with respect to blood vessel segmentation, of weak visibility of vessel pattern in the OCT fundus image. To address this problem, a boosting learning approach uses three-dimensional (3D) information to effect automated segmentation of retinal blood vessels. The automated blood vessel segmentation technique described herein is based on 3D spectral domain OCT and provides accurate vessel pattern for clinical analysis, for retinal image registration, and for early diagnosis and monitoring of the progression of glaucoma and other retinal diseases. The technique employs a machine learning algorithm to identify blood vessel automatically in 3D OCT image, in a manner that does not rely on retinal layer segmentation.
摘要翻译： 在眼部疾病如青光眼和糖尿病性视网膜病变的早期检测和监测的背景下，使用光学相干断层摄影技术在OCT眼底图像中难以识别血管图案。 为了解决这个问题，增强学习方法使用三维（3D）信息来实现视网膜血管的自动分割。 本文描述的自动血管分割技术基于3D光谱域OCT，并提供用于临床分析，视网膜图像配准以及早期诊断和监测青光眼和其他视网膜疾病进展的精确血管模式。 该技术采用机器学习算法，以不依赖于视网膜层分割的方式在3D OCT图像中自动识别血管。
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公开(公告)号：US08503836B2
公开(公告)日：2013-08-06
申请号：US13014151
申请日：2011-01-26
申请人： Hiroshi Ishikawa , Toshifumi Hasama , Hitoshi Kawashima , Kenji Kintaka , Masahiko Mori , Hisato Uetsuka , Hiroyuki Tsuda , Keisuke Sorimoto
发明人： Hiroshi Ishikawa , Toshifumi Hasama , Hitoshi Kawashima , Kenji Kintaka , Masahiko Mori , Hisato Uetsuka , Hiroyuki Tsuda , Keisuke Sorimoto
CPC分类号： G02B6/2773 , G02B6/12021 , G02B6/3594 , G02F1/313
摘要： To provide a waveguide type wavelength domain optical switch which makes it possible to use a cheap lens, makes it possible to correct aberration of the demultiplexed wavelengths produced in a plurality of waveguide type demultiplexing circuits, a wavelength domain optical switch is provided with: an integrated element formed by laminating three or more waveguide type demultiplexing circuits; a first lens for collecting light emitted from the integrated element; a polarization separation element for separating light emitted from the first lens into X polarization and Y polarization and emitting the X polarization and the Y polarization at different angles; a second lens for collecting the X polarization and the Y polarization; a first reflective optical phase modulator for reflecting the collected X polarization and Y polarization at any angles; a ½-wavelength plate disposed between the second lens and the first reflective optical phase modulator in order to make polarization directions of the X polarization and the Y polarization identical; and a second reflective optical phase modulator for inputting light from the first reflective optical phase modulator into one of the waveguide type demultiplexing circuits.
摘要翻译： 为了提供使得可以使用廉价透镜的波导型波长域光开关，可以校正在多个波导型解复用电路中产生的解复用波长的像差，波长域光开关具有：集成 通过层叠三个或更多个波导型解复用电路形成的元件; 用于收集从所述集成元件发射的光的第一透镜; 用于将从第一透镜发射的光分离成X偏振和Y偏振并以不同角度发射X偏振和Y偏振的偏振分离元件; 用于收集X偏振和Y偏振的第二透镜; 用于以任何角度反射所收集的X偏振和Y偏振的第一反射光学相位调制器; 设置在第二透镜和第一反射光学相位调制器之间的1/2波长板，以使X偏振和Y偏振的偏振方向相同; 以及第二反射光学相位调制器，用于将来自第一反射型光学相位调制器的光输入波导型解复用电路之一。
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6.发明授权Document processing system, information processing unit, display medium, computer readable medium, document processing method, and computer data signal 有权文件处理系统，信息处理单元，显示介质，计算机可读介质，文件处理方法和计算机数据信号公开(公告)号：US08375284B2
公开(公告)日：2013-02-12
申请号：US11497371
申请日：2006-08-02
申请人： Yoshitsugu Hirose , Hiroyuki Hattori , Toshiroh Shimada , Tomoyuki Shoya , Shigehiko Sasaki , Minoru Koshimizu , Kiwame Tokai , Sho Hasegawa , Hiroshi Ishikawa
发明人： Yoshitsugu Hirose , Hiroyuki Hattori , Toshiroh Shimada , Tomoyuki Shoya , Shigehiko Sasaki , Minoru Koshimizu , Kiwame Tokai , Sho Hasegawa , Hiroshi Ishikawa
CPC分类号： G06F17/30011
摘要： A document processing system includes: a document management server that manages document data and an access key to access to the document data in association with each other; and an information processing unit including: a processing section; and a display detachably linked to the processing section by one of wired and wireless connection, the display holding an image of a document, the display storing the access key to access to the document data, the processing section comprising: a connection section to which the display is linked so as to read the access key from the display; a document acquisition section that acquires the document data corresponding to the access key read from the display from the document management server; and a document processing section that processes the document data acquired from the document management server.
摘要翻译： 文件处理系统包括：文档管理服务器，其管理文档数据和访问密钥以访问与之相关联的文档数据; 以及信息处理单元，包括：处理部; 以及通过有线和无线连接之一可拆卸地链接到所述处理部分的显示器，所述显示器保持文档的图像，所述显示器存储所述访问密钥以访问所述文档数据，所述处理部分包括：连接部分， 显示被链接以从显示器读取访问密钥; 文档获取部分，从文档管理服务器获取与从显示器读取的访问密钥对应的文档数据; 以及处理从文件管理服务器获取的文档数据的文档处理部。
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公开(公告)号：US08086112B2
公开(公告)日：2011-12-27
申请号：US12874030
申请日：2010-09-01
IPC分类号： H04B10/06
CPC分类号： G02F1/3517
摘要： An optical gate switch circuit includes: an asymmetric Mach-Zehnder interferometer having an optical path that outputs control light and probe light to a second optical directional coupler via a first optical directional coupler and an optical phase modulation element, and another optical path that connects a third optical directional coupler to which the probe light is input, to the second optical directional coupler via a variable optical attenuator and an optical phase shifter; and a bandpass filter connected to the second optical directional coupler.
摘要翻译： 光栅开关电路包括：非对称马赫 - 曾德干涉仪，其具有经由第一光学定向耦合器和光相位调制元件将控制光和探测光输出到第二光学定向耦合器的光路，以及连接 通过可变光衰减器和光学移相器将探测光输入的第三光学定向耦合器连接到第二光学定向耦合器; 以及连接到第二光学定向耦合器的带通滤波器。
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公开(公告)号：US20100250226A1
公开(公告)日：2010-09-30
申请号：US12724700
申请日：2010-03-16
IPC分类号： G06F17/50
CPC分类号： G06F17/5036
摘要： A technique for enhancing the execution efficiency of simulation of a hybrid system. A continuous system simulator receives a request for evaluation of an event generating conditional expression for an event to be processed by a discrete system simulator, from the discrete system simulator. The event generating conditional expression is evaluated by referring to the value of a first variable describing a continuous system. Until evaluation of the event generating conditional expression indicates true, the continuous system simulator repeats simulation of advancing the current time by a step time interval and evaluation of the event generating conditional expression. When evaluation of the event generating conditional expression indicates true, the continuous system simulator sends current time data and the value of a second variable describing the continuous system which is referred to by the discrete simulator, to the discrete simulator.
摘要翻译： 一种提高混合系统仿真执行效率的技术。 连续系统模拟器从离散系统模拟器接收用于评估由离散系统模拟器处理的事件的事件生成条件表达式的请求。 通过参照描述连续系统的第一个变量的值来评估产生条件表达式的事件。 在产生条件表达式的事件的评估表示为真时，连续系统模拟器重复以步进时间间隔推进当前时间的模拟，并且评估事件产生条件表达式。 当事件生成条件表达式的评估表示为真时，连续系统模拟器将当前时间数据和描述由离散模拟器引用的连续系统的第二个变量的值发送到离散模拟器。
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公开(公告)号：US20090307654A1
公开(公告)日：2009-12-10
申请号：US12478815
申请日：2009-06-05
申请人： Hiroshi Ishikawa , Hiroaki Nakamura , Kouichi Ono
发明人： Hiroshi Ishikawa , Hiroaki Nakamura , Kouichi Ono
CPC分类号： G06F11/3604 , G06F8/20 , G06F11/3612
摘要： A system, method and computer program for generating a sequence diagram that specifies processing among modules included in source code. First, a source code is acquired and then analyzed to generate a log acquisition code for acquiring an execution log. Then, a program including the generated log acquisition code is executed to acquire execution log information on the execution of the program. On the basis of the acquired execution log information, automaton information on states and transitions among the states is extracted, and then the extracted automaton information is converted into sequence diagram component information on components constituting a sequence diagram. Thereafter, a sequence diagram is generated based on the converted sequence diagram component information.
摘要翻译： 一种用于生成指定源代码中包含的模块之间的处理的序列图的系统，方法和计算机程序。 首先，获取源代码，然后分析以产生用于获取执行日志的日志获取代码。 然后，执行包括产生的日志获取代码的程序，以获取关于程序的执行的执行日志信息。 基于获取的执行日志信息，提取状态之间的状态和转换的自动机信息，然后将提取的自动机信息转换成关于构成序列图的组件的序列图分量信息。 此后，基于转换的序列图组件信息生成序列图。
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公开(公告)号：US07373066B2
公开(公告)日：2008-05-13
申请号：US11582458
申请日：2006-10-18
IPC分类号： G02B6/10
CPC分类号： G02B6/122
摘要： In a multiple optical waveguide device, a transparent plate is bonded or joined on the top surface of a clad with which optical circuits and quartz glass substrates are covered, and optical reflection film is provided on the fringing area or the whole area of a joint surface of the transparent plate with the clad. Optical circuits or waveguide patterns can be recognized easily by visual inspection.
摘要翻译： 在多重光波导装置中，透明板与覆盖光电路和石英玻璃基板的包层的顶面接合或接合，在接合面的边缘区域或整个区域设置光反射膜 的透明板与包层。 光学电路或波导图案可以通过目视检查轻松识别。
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