公开(公告)号：US06567861B1

公开(公告)日：2003-05-20

申请号：US08931979

申请日：1997-09-17

Applicant: Manoj V. S. Kasichainula ,  Zhiyong Li

Inventor： Manoj V. S. Kasichainula ,  Zhiyong Li

IPC: G06F946

CPC classification number: G06F9/548

Abstract: Proxy data stream handling and complex object parameter handling allow object oriented programs to be run as distributed programs without any explicit networking code, and without using an interface definition language (IDL). Two proxies are generated dynamically that allow method calls written for local invocation to be invoked over a network. These dynamically-generated proxies allow calls to flow across a network as if they were local, and contain support for using data stream and complex objects as parameters.

Abstract translation: 代理数据流处理和复杂的对象参数处理允许面向对象的程序作为分布式程序运行，而不需要任何明确的联网代码，而不使用接口定义语言（IDL）。 动态生成两个代理，允许通过网络调用为本地调用编写的方法调用。 这些动态生成的代理允许调用通过网络流动，就像它们是本地的，并且包含使用数据流和复杂对象作为参数的支持。

公开(公告)号：US06941561B1

公开(公告)日：2005-09-06

申请号：US09692990

申请日：2000-10-20

Applicant: Manoj V. S. Kasichainula ,  Zhiyong Li

Inventor： Manoj V. S. Kasichainula ,  Zhiyong Li

IPC: G06F9/46

CPC classification number: G06F9/548

Abstract: Proxy data stream handling and complex object parameter handling allow object oriented programs to be run as distributed programs without any explicit networking code, and without using an interface definition language (IDL). Two proxies are generated dynamically that allow method calls written for local invocation to be invoked over a network. These dynamically-generated proxies allow calls to flow across a network as if they were local, and contain support for using data stream and complex objects as parameters.

Abstract translation: 代理数据流处理和复杂对象参数处理允许以面向对象的程序作为分布式程序运行，而不需要任何明确的联网代码，而不使用接口定义语言（IDL）。 动态生成两个代理，允许通过网络调用为本地调用编写的方法调用。 这些动态生成的代理允许调用通过网络流动，就像它们是本地的，并且包含使用数据流和复杂对象作为参数的支持。

公开(公告)号：US6011918A

公开(公告)日：2000-01-04

申请号：US64925

申请日：1998-04-22

Applicant: Geoffrey Alexander Cohen ,  James P. Gray ,  David Louis Kaminsky ,  Manoj V. S. Kasichainula ,  Richard Adam King ,  Zhiyong Li ,  Phillip Allan Stone

Inventor： Geoffrey Alexander Cohen ,  James P. Gray ,  David Louis Kaminsky ,  Manoj V. S. Kasichainula ,  Richard Adam King ,  Zhiyong Li ,  Phillip Allan Stone

IPC: G06F9/44 ,  G06F9/46

CPC classification number: G06F8/30 ,  G06F9/465

Abstract: Methods, systems and computer program products are provided for automatically generating client/server applications from an application written to execute on a single processing system. The application has program classes and programmed methods associated with the objects. Each program class in the application is identified and the relationships between programmed methods in the classes is determined. The relationships between the programmed methods in the identified classes are then weighted based on the activity of the relationship. Similarly, each identified class in the application is also weighted based on the computing resources required by the identified class. The identified classes are then partitioned into client classes and server classes based on the weighted relationships between the programmed methods in the classes, the weight associated with each class and a computing topology associated with a target client processing system. The resulting client and server partition may then be used for code generation and distribution based on the capabilities of a requesting computer system.

Abstract translation: 提供了方法，系统和计算机程序产品，用于从写入在单个处理系统上执行的应用程序自动生成客户端/服务器应用程序。 应用程序具有与对象相关联的程序类和编程方法。 识别应用程序中的每个程序类，并确定类中编程方法之间的关系。 然后基于关系的活动来对所识别的类中的编程方法之间的关系加权。 类似地，应用程序中的每个已标识的类也基于所识别的类所需的计算资源进行加权。 然后，基于类中编程的方法，与每个类相关联的权重和与目标客户端处理系统相关联的计算拓扑之间的加权关系，将所识别的类划分为客户端类和服务器类。 然后，所得到的客户端和服务器分区可以用于基于请求计算机系统的能力的代码生成和分发。

公开(公告)号：US10520440B2

公开(公告)日：2019-12-31

申请号：US14377524

申请日：2012-02-08

Applicant: Devin Alexander Mourey ,  James William Stasiak ,  James Elmer Abbott, Jr. ,  Zhiyong Li

Inventor： Devin Alexander Mourey ,  James William Stasiak ,  James Elmer Abbott, Jr. ,  Zhiyong Li

IPC: G01J3/44 ,  G01N21/65

Abstract: Molecule sensing apparatus. The apparatus has first and second chambers, an input port extending into the first chamber, a fluid channel extending from the first chamber to the second chamber, and a surface-enhanced substrate in the second chamber.

公开(公告)号：US09709538B2

公开(公告)日：2017-07-18

申请号：US14239330

申请日：2011-09-30

Applicant: Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

Inventor： Wei Wu ,  Zhiyong Li ,  Ansoon Kim ,  Min Hu ,  Michael Josef Stuke

IPC: G01N31/22 ,  G01N21/64 ,  G01N21/65 ,  B01L3/00 ,  B82Y15/00

CPC classification number: G01N31/22 ,  B01L3/5085 ,  B01L3/50853 ,  B01L2200/141 ,  B01L2300/0636 ,  B01L2300/069 ,  B01L2300/0819 ,  B82Y15/00 ,  G01N21/648 ,  G01N21/658 ,  G01N2201/0227 ,  G01N2201/023 ,  Y10T436/25

Abstract: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.

公开(公告)号：US09678013B2

公开(公告)日：2017-06-13

申请号：US14394295

申请日：2012-04-20

Applicant: Alexandre M. Bratkovski ,  Zhiyong Li ,  Wei Wu ,  Min Hu ,  R. Stanley Williams ,  Ansoon Kim

Inventor： Alexandre M. Bratkovski ,  Zhiyong Li ,  Wei Wu ,  Min Hu ,  R. Stanley Williams ,  Ansoon Kim

IPC: G01N21/01 ,  G01N21/65 ,  G01N35/00 ,  B01L3/00 ,  G01N21/64

CPC classification number: G01N21/658 ,  B01L3/5088 ,  B01L2300/0627 ,  B01L2300/0819 ,  B01L2300/161 ,  G01N21/648 ,  G01N35/00009 ,  G01N2035/00019

Abstract: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.

公开(公告)号：US09592001B2

公开(公告)日：2017-03-14

申请号：US14406601

申请日：2012-07-29

Applicant: Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

Inventor： Steven Barcelo ,  Zhiyong Li ,  Ansoon Kim ,  Gary Gibson

IPC: G01J3/44 ,  A61B5/1459 ,  G01N21/65 ,  A61B5/00

CPC classification number: A61B5/1459 ,  A61B5/0075 ,  A61B5/6862 ,  G01N21/658

Abstract: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.

Abstract translation: 可植入纳米传感器包括待植入流体导管内的支架。 支架在支架表面有一个井。 可植入纳米传感器还包括设置在井中的纳米级图案感测基片。 纳米级图案化感测衬底将产生光学散射响应信号，该信号指示由光学刺激信号询问时由流体导管携带的流体中分析物的存在。

公开(公告)号：US09310306B2

公开(公告)日：2016-04-12

申请号：US14006436

申请日：2011-03-24

Applicant: Zhiyong Li ,  Ivan Naumov ,  Farzad Parvaresh

Inventor： Zhiyong Li ,  Ivan Naumov ,  Farzad Parvaresh

IPC: G01J3/44 ,  G01N21/65 ,  B05D3/00

CPC classification number: G01N21/65 ,  B05D3/007 ,  G01N21/658

Abstract: An apparatus for use in sensing applications includes a substrate and a plurality of clusters arranged in an aperiodic configuration on the substrate, wherein each of the plurality of clusters is formed of a plurality of Raman-active material nano-particles, and wherein each of the Raman-active material nano-particles is positioned in a substantially ordered configuration with respect to each other in each of the respective plurality of clusters.

Abstract translation: 用于感测应用的装置包括基板和在基板上以非周期配置布置的多个簇，其中多个簇中的每一个由多个拉曼活性材料纳米颗粒形成，并且其中 拉曼活性材料纳米颗粒在相应的多个簇中的每一个中相对于彼此定位成基本排列的构型。

公开(公告)号：US20150241355A1

公开(公告)日：2015-08-27

申请号：US14406653

申请日：2012-07-31

Applicant: Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Steven Barcelo ,  Ansoon Kim ,  Mineo Yamakawa ,  Zhang-Lin Zhou ,  Huei Pei Kuo

Inventor： Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Steven Barcelo ,  Ansoon Kim ,  Mineo Yamakawa ,  Zhang-Lin Zhou ,  Huei Pei Kuo

IPC: G01N21/65 ,  A61F2/02 ,  A61F2/82 ,  G02B5/10

CPC classification number: G01N21/658 ,  A61F2/02 ,  A61F2/82 ,  G01N2201/068 ,  G02B5/10 ,  Y10T29/49826

Abstract: According to an example, an apparatus for performing spectroscopy includes a parabolic reflector and a plurality of surface-enhanced Raman spectroscopy (SERS) elements spaced from the parabolic reflector and positioned substantially at a focal point of the parabolic reflector. The parabolic reflector is to reflect Raman scattered light emitted from molecules in a near field generated by the plurality of SERS elements to substantially increase the flux of the Raman scattered light emitted out of the apparatus.

Abstract translation: 根据一个实例，用于执行光谱学的装置包括抛物面反射器和与抛物面反射器间隔开并且基本上位于抛物面反射器的焦点的多个表面增强拉曼光谱（SERS）元件。 抛物面反射器是反射由多个SERS元件产生的近场中的分子发射的拉曼散射光，以大大增加从该装置发出的拉曼散射光的通量。

公开(公告)号：US09001324B2

公开(公告)日：2015-04-07

申请号：US13810982

申请日：2010-07-30

Applicant: Zhiyong Li ,  Min Hu ,  Wei Wu

Inventor： Zhiyong Li ,  Min Hu ,  Wei Wu

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01N21/658

Abstract: A surface enhanced Raman spectroscopy (SERS) probe apparatus and a method of SERS probing employ Raman-active surfaces of a plurality of nanoscale field concentrator (NFC) structures at a terminal end of an optical fiber. The SERS probe apparatus includes an optical fiber having an optical path and a terminal end that terminates the optical path. The SERS probe apparatus further includes a plurality of NFC structures and nanoparticles on surfaces of the plurality of NFC structures. First ends of the NFC structures are adjacent to the terminal end of optical fiber. The nanoparticles are Raman active to an analyte.

Abstract translation: 表面增强拉曼光谱（SERS）探针装置和SERS探测的方法在光纤的末端使用多个纳米尺度场集中器（NFC）结构的拉曼活性表面。 SERS探针装置包括具有光路的光纤和终止光路的终端。 SERS探针装置还包括在多个NFC结构的表面上的多个NFC结构和纳米颗粒。 NFC结构的第一端与光纤的终端相邻。 纳米颗粒是对分析物有活性的拉曼。