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公开(公告)号:US09709538B2
公开(公告)日:2017-07-18
申请号:US14239330
申请日:2011-09-30
申请人: Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
发明人: Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
CPC分类号: G01N31/22 , B01L3/5085 , B01L3/50853 , B01L2200/141 , B01L2300/0636 , B01L2300/069 , B01L2300/0819 , B82Y15/00 , G01N21/648 , G01N21/658 , G01N2201/0227 , G01N2201/023 , Y10T436/25
摘要: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.
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公开(公告)号:US20140199778A1
公开(公告)日:2014-07-17
申请号:US14239330
申请日:2011-09-30
申请人: Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
发明人: Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
IPC分类号: G01N31/22
CPC分类号: G01N31/22 , B01L3/5085 , B01L3/50853 , B01L2200/141 , B01L2300/0636 , B01L2300/069 , B01L2300/0819 , B82Y15/00 , G01N21/648 , G01N21/658 , G01N2201/0227 , G01N2201/023 , Y10T436/25
摘要: Devices to detect a substance and methods of producing such a device are disclosed. An example device to detect a substance includes a housing defining an externally accessible chamber and a seal to enclose at least a portion of the chamber. The example device also includes a substrate includes nanoparticles positioned within the chamber. The nanoparticles to react to the substance when exposed thereto. The example device also includes a non-analytic solution within the chamber to protect the nanoparticles from premature exposure.
摘要翻译: 公开了检测物质的装置和制造这种装置的方法。 用于检测物质的示例性装置包括限定外部可触及室的壳体和用于封闭室的至少一部分的密封件。 该示例性装置还包括基底,其包括位于腔室内的纳米颗粒。 纳米颗粒暴露于物质时与物质反应。 该示例性装置还包括室内的非分析溶液以保护纳米颗粒免于过早曝光。
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公开(公告)号:US20130107250A1
公开(公告)日:2013-05-02
申请号:US13282606
申请日:2011-10-27
申请人: Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
发明人: Wei Wu , Zhiyong Li , Ansoon Kim , Min Hu , Michael Josef Stuke
IPC分类号: G01N21/01
CPC分类号: B82Y40/00 , B82Y15/00 , G01N21/554 , G01N21/658
摘要: A structure for molecular analysis is disclosed. The structure includes a nanostructure and a nanoparticle attached to the nanostructure, wherein the nanostructure is free-standing and wherein the nanoparticle, the nanostructure or both the nanoparticle and the nanostructure are coated with a metal coating; or a plurality of nanoparticles, wherein the plurality of nanoparticles is free-standing and wherein each nanoparticle in the plurality is coated with a metal coating and is separated from one other nanoparticle or two other nanoparticles by a distance of 0.5 nm to 1 nm. A method for preparing the structure for molecular analysis is also disclosed.
摘要翻译: 公开了一种用于分子分析的结构。 该结构包括纳米结构和连接到纳米结构的纳米颗粒,其中纳米结构是独立的,并且其中纳米颗粒,纳米结构或纳米颗粒和纳米结构二者都涂覆有金属涂层; 或多个纳米颗粒,其中所述多个纳米颗粒是独立的,并且其中所述多个纳米颗粒中的每个纳米颗粒涂覆有金属涂层,并且与另外一个纳米颗粒或两个其它纳米颗粒分开0.5nm至1nm的距离。 还公开了用于分子分析结构的制备方法。
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公开(公告)号:US20130194570A1
公开(公告)日:2013-08-01
申请号:US13363006
申请日:2012-01-31
申请人: Wei WU , Michael Josef Stuke , Zhiyong Li , James Elmer Abbott, JR. , Min Hu , Ansoon Kim
发明人: Wei WU , Michael Josef Stuke , Zhiyong Li , James Elmer Abbott, JR. , Min Hu , Ansoon Kim
CPC分类号: G01J3/44 , G01J3/0205 , G01J3/26
摘要: An apparatus for performing spectroscopy includes an optical waveguide comprising a fluidic channel to receive a fluid sample, in which the optical waveguide is to propagate lightwaves at a set of frequencies. The apparatus also includes a wavelength selective device coupled to the optical waveguide, in which the wavelength selective device comprises a predetermined bandwidth and is to capture frequencies of light within the predetermined bandwidth. The apparatus further includes a detector coupled to the wavelength selective device to generate signals that identify the frequencies captured by the wavelength selective device.
摘要翻译: 用于执行光谱学的装置包括光波导,其包括用于接收流体样品的流体通道,其中光波导将以一组频率传播光波。 该装置还包括耦合到光波导的波长选择装置,其中波长选择装置包括预定带宽并且捕获预定带宽内的光的频率。 该装置还包括耦合到波长选择装置的检测器,以产生识别由波长选择装置捕获的频率的信号。
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公开(公告)号:US09678013B2
公开(公告)日:2017-06-13
申请号:US14394295
申请日:2012-04-20
申请人: Alexandre M. Bratkovski , Zhiyong Li , Wei Wu , Min Hu , R. Stanley Williams , Ansoon Kim
发明人: Alexandre M. Bratkovski , Zhiyong Li , Wei Wu , Min Hu , R. Stanley Williams , Ansoon Kim
CPC分类号: G01N21/658 , B01L3/5088 , B01L2300/0627 , B01L2300/0819 , B01L2300/161 , G01N21/648 , G01N35/00009 , G01N2035/00019
摘要: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.
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公开(公告)号:US20150065390A1
公开(公告)日:2015-03-05
申请号:US14394295
申请日:2012-04-20
申请人: Alexandre M. Bratkovski , Zhiyong Li , Wei Wu , Min Hu , R. Stanley Williams , Ansoon Kim
发明人: Alexandre M. Bratkovski , Zhiyong Li , Wei Wu , Min Hu , R. Stanley Williams , Ansoon Kim
CPC分类号: G01N21/658 , B01L3/5088 , B01L2300/0627 , B01L2300/0819 , B01L2300/161 , G01N21/648 , G01N35/00009 , G01N2035/00019
摘要: Examples of integrated sensors are disclosed herein. An example of an integrated sensor includes a substrate and a sensing member formed on a surface of the substrate. The sensing member includes collapsible signal amplifying structures and an area surrounding the collapsible signal amplifying structures that enables self-positioning of droplets exposed thereto toward the collapsible signal amplifying structures.
摘要翻译: 本文公开了集成传感器的示例。 集成传感器的示例包括形成在基板的表面上的基板和感测构件。 感测构件包括可折叠信号放大结构和围绕可折叠信号放大结构的区域,其使得能够将暴露于其的液滴自动定位到可折叠信号放大结构。
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公开(公告)号:US09377409B2
公开(公告)日:2016-06-28
申请号:US13194556
申请日:2011-07-29
申请人: Min Hu , Zhiyong Li , Fung Suong Ou , Ansoon Kim
发明人: Min Hu , Zhiyong Li , Fung Suong Ou , Ansoon Kim
CPC分类号: G01N21/658 , B82Y20/00 , G01J3/0256 , G01J3/4412 , G01N2201/06113 , Y10S977/954 , Y10T29/49
摘要: In a method of fabricating an apparatus for use in a sensing application, a plurality of nano-fingers are formed on a substrate and a Raman-active material nano-particle is formed on respective tips of the nano-fingers. In addition, the Raman-active material nano-particles on the tips of adjacent ones of the nano-fingers are caused to come into contact with the Raman-active material nano-particle on the tip of at least another one of the plurality of nano-fingers to form respective clusters and the clusters of Raman-active material nano-particles are transferred to a component layer from the plurality of nano-fingers while maintaining a spatial relationship between the contacting Raman-active material nano-particles.
摘要翻译: 在制造用于感测应用的装置的方法中,在衬底上形成多个纳米指,并且在纳米手指的各个尖端上形成拉曼活性材料纳米颗粒。 另外,使相邻的纳米指尖的拉曼活性物质纳米粒子与多个纳米尺寸中的至少另一个的前端的拉曼活性物质纳米粒子接触 - 形成相应的簇,并且拉曼活性材料纳米颗粒簇从多个纳米指转移到组分层,同时保持接触拉曼活性材料纳米颗粒之间的空间关系。
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公开(公告)号:US09638625B2
公开(公告)日:2017-05-02
申请号:US14345277
申请日:2011-10-27
申请人: Ansoon Kim , Zhiyong Li , Wei Wu
发明人: Ansoon Kim , Zhiyong Li , Wei Wu
CPC分类号: G01N21/05 , B82Y20/00 , G01N21/554 , G01N21/658 , G01N33/491 , G01N2001/4088 , G01N2021/651
摘要: An apparatus for filtering species in a fluid includes a body having a first side and a second side, a first set of nano-fingers positioned on the body near the first side, a second set of nano-fingers positioned on the body closer to the second side than the first set of nano-fingers, wherein the nano-fingers in the second set of nano-fingers are arranged on the body at a relatively more densely than the nano-fingers in the first set of nano-fingers, and a cover positioned over the first set of nano-fingers and the second set of nano-fingers to form a channel with the body within which the first and second sets of nano-fingers are positioned.
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公开(公告)号:US20140198314A1
公开(公告)日:2014-07-17
申请号:US14239336
申请日:2011-10-18
申请人: Zhiyong Li , Ansoon Kim
发明人: Zhiyong Li , Ansoon Kim
IPC分类号: G01J3/44
CPC分类号: G01J3/4412 , G01N21/253 , G01N21/658
摘要: A molecular sensing device includes a substrate; a well i) formed in a material that is positioned on a surface of the substrate or ii) formed in a surface of the substrate; a signal amplifying structure positioned in the wed; and an immersion fluid deposited into the well and surrounding the signal amplifying structure.
摘要翻译: 分子感测装置包括基板; 形成在位于基板的表面上的材料中,或ii)形成在基板的表面中的材料; 定位在所述信号放大结构中的信号放大结构; 以及沉积到井中并围绕信号放大结构的浸没流体。
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公开(公告)号:US09592001B2
公开(公告)日:2017-03-14
申请号:US14406601
申请日:2012-07-29
申请人: Steven Barcelo , Zhiyong Li , Ansoon Kim , Gary Gibson
发明人: Steven Barcelo , Zhiyong Li , Ansoon Kim , Gary Gibson
IPC分类号: G01J3/44 , A61B5/1459 , G01N21/65 , A61B5/00
CPC分类号: A61B5/1459 , A61B5/0075 , A61B5/6862 , G01N21/658
摘要: An implantable nanosensor includes a stent to be implanted inside a fluid conduit. The stent has a well in a surface of the stent. The implantable nanosensor further includes a nanoscale-patterned sensing substrate disposed in the well. The nanoscale-patterned sensing substrate is to produce an optical scattering response signal indicative of a presence of an analyte in a fluid carried by the fluid conduit when interrogated by an optical stimulus signal.
摘要翻译: 可植入纳米传感器包括待植入流体导管内的支架。 支架在支架表面有一个井。 可植入纳米传感器还包括设置在井中的纳米级图案感测基片。 纳米级图案化感测衬底将产生光学散射响应信号,该信号指示由光学刺激信号询问时由流体导管携带的流体中分析物的存在。
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