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1.发明授权公开(公告)号：US06699839B1
公开(公告)日：2004-03-02
申请号：US09691150
申请日：2000-10-19
IPC分类号： A61K3800
CPC分类号： C07K14/315 , A61K38/00
摘要： Mutacin are bactericidal substances of proteinaceous natures produced by Streptococcus mutans. Lantibiotics are antibacterial substances containing posttranslationnally modified amino acids such as lanthionine. The present invention teaches a simple method of purifying mutacin B-Ny266 from Streptococcus mutans strain Ny266 to homogeneity. The present invention further teaches the primary amino acid sequence of mutacin B-Ny266 as well as its proposed modified structure. Further, the present invention teaches compositions comprising mutacin B-Ny266 as well as methods for the treatment and/or prophylaxy of bacterial infections comprising an administration of a suitable dose of composition comprising mutacin B-Ny266.
摘要翻译： 变态链霉菌是由变形链球菌产生的蛋白质性质的杀菌物质。 拉链抗生素是含有经过翻译后修饰的氨基酸如羊毛硫蛋白的抗菌物质。 本发明教导了将Mutacin B-Ny266从变异链球菌菌株Ny266纯化为均质的简单方法。 本发明进一步教导了Mutacin B-Ny266的初级氨基酸序列以及其提出的修饰结构。 此外，本发明教导了包含mutacin B-Ny266的组合物以及用于治疗和/或预防细菌感染的方法，包括给予包含Mutacin B-Ny266的合适剂量的组合物。
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公开(公告)号：US06218362B1
公开(公告)日：2001-04-17
申请号：US08924952
申请日：1997-09-08
IPC分类号： A61K3800
CPC分类号： C07K14/315 , A61K38/00
摘要： Mutacin are bactericidal substances of proteinaceous natures produced by Streptococcus mutans. Lantibiotics are antibacterial substances containing posttranslationnally modified amino acids such as lanthionine. The present invention teaches a simple method of purifying mutacin B-Ny266 from Streptococcus mutans strain Ny266 to homogeneity. The present invention further teaches the primary amino acid sequence of mutacin B-Ny266 as well as its proposed modified structure. Further, the present invention teaches compositions comprising mutacin B-Ny266 as well as methods for the treatment and/or prophylaxy of bacterial infections comprising an administration of a suitable dose of composition comprising mutacin B-Ny266.
摘要翻译： 变态链霉菌是由变形链球菌产生的蛋白质性质的杀菌物质。 拉链抗生素是含有经过翻译后修饰的氨基酸如羊毛硫蛋白的抗菌物质。 本发明教导了将Mutacin B-Ny266从变异链球菌菌株Ny266纯化为均质的简单方法。 本发明进一步教导了Mutacin B-Ny266的初级氨基酸序列以及其提出的修饰结构。 此外，本发明教导了包含mutacin B-Ny266的组合物以及用于治疗和/或预防细菌感染的方法，包括给予包含Mutacin B-Ny266的合适剂量的组合物。
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公开(公告)号：US07718740B2
公开(公告)日：2010-05-18
申请号：US11911219
申请日：2006-04-12
IPC分类号： C08L77/00
CPC分类号： C08L77/12 , C08L77/00 , C08L77/02 , C08L77/06 , C08L2666/20
摘要： The invention relates to a mixture comprising by weight, to give a total of 100%, 99-10% a polyamide block and polyether block copolymer (A) predominately consisting of lauryl lactam radicals, 1-99% at least on type of polymer (B) selected from polyamides other than polyamide 12, copolyamides which do not consist of the lauryl lactam radicals and the polyamide block and polyether block copolymers whose polyamide blocks do not predominantly consist of the lauryl lactam radicals. The articles, for example, films, foils, strings and tubes made from the inventive mixture are also disclosed.
摘要翻译： 本发明涉及一种包含重量比的混合物，以总共100％，99-10％为主要由月桂基内酰胺基团组成的聚酰胺嵌段和聚醚嵌段共聚物（A），1-99％的至少一种类型的聚合物 B）选自聚酰胺12以外的聚酰胺，不由月桂基内酰胺基团组成的共聚酰胺和聚酰胺嵌段和聚醚嵌段共聚物，其聚酰胺嵌段不主要由月桂基内酰胺基团组成。 还公开了由本发明混合物制成的制品，例如薄膜，箔，线和管。
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公开(公告)号：US07119152B1
公开(公告)日：2006-10-10
申请号：US09718427
申请日：2000-11-24
IPC分类号： C08L65/00
CPC分类号： C08L67/02 , Y10S525/902 , C08L2666/02
摘要： The present invention relates to thermoplastic polyesters, which comprise, by weight: (i) a thermoplastic polyester; (ii) an impact modifier comprising: (a) a core-shell copolymer (A); (b) an ethylene copolymer (B) chosen from ethylene-unsaturated carboxylic acid anhydride copolymers (B1), ethylene-unsaturated epoxide copolymers (B2) and blends thereof; (iii) the (B)/(A) ratio being between 40/60 and 10/90 for proportions of impact modifier between 18 and 40% in 82 to 60% of polyester, respectively; (iv) the (B)/(A) ratio being between 40/60 and 25/75 for proportions of impact modifier between 2 and 18% in 98 to 82% of polyester, respectively. It is particularly useful for PET and PBT.
摘要翻译： 本发明涉及热塑性聚酯，其包含：（i）热塑性聚酯; （ii）抗冲改性剂，其包含：（a）核 - 壳共聚物（A）; （b）选自乙烯 - 不饱和羧酸酐共聚物（B1），乙烯 - 不饱和环氧化物共聚物（B2）及其共混物的乙烯共聚物（B） （iii）分别在82至60％的聚酯中，抗冲改性剂的比例为18至40％时，（B）/（A）的比率为40/60至10/90; （iv）分别在98至82％的聚酯中，抗冲改性剂的比例为2至18％时，（B）/（A）比为40/60至25/75。 它对PET和PBT特别有用。
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公开(公告)号：US20050245443A1
公开(公告)日：2005-11-03
申请号：US10834886
申请日：2004-04-30
申请人： Ismail Fliss , Michel Desbiens , Christophe Lacroix , Imane Tahiri , Regis-Olivier Benech , Ehab Kheadr
发明人： Ismail Fliss , Michel Desbiens , Christophe Lacroix , Imane Tahiri , Regis-Olivier Benech , Ehab Kheadr
IPC分类号： A61K38/00 , A61K38/16 , A61P31/04 , C07K14/195 , C07K14/335 , C12N1/20 , C12N15/31 , C12P21/02
CPC分类号： C07K14/335 , A61K38/00
摘要： The present invention concerns an isolated bacteriocin, Divergicin M35, derived form Carnobacterium divergens M35. It also concerns a composition comprising an effective amount of Divergicin M35 and the use of that bacteriocin to kill or limit the proliferation of a microorganism.
摘要翻译： 本发明涉及分离的细菌素Divergicin M35，衍生自分枝杆菌M35。 它还涉及一种包含有效量的分枝杆菌素M35的组合物，以及使用该细菌素来杀死或限制微生物的增殖。
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6.发明授权公开(公告)号：US06962754B2
公开(公告)日：2005-11-08
申请号：US10174507
申请日：2002-06-19
申请人： Philippe Bussi , Christophe Lacroix , David Silagy
发明人： Philippe Bussi , Christophe Lacroix , David Silagy
IPC分类号： B32B27/30 , B32B7/10 , B32B27/08 , B32B27/34 , C09J7/02 , C09J177/02 , C09J177/04 , C09J177/06
CPC分类号： B32B27/08 , B32B7/10 , B32B27/18 , B32B27/20 , B32B27/304 , Y10T156/10 , Y10T428/31504 , Y10T428/31725 , Y10T428/31743 , Y10T428/3175
摘要： A structure made of a fluoropolymer layer and directly attached to one of its sides a tie layer based on a polyamide which results from the condensation of at least one diacid and at least one diamine of the following formula (1): in which R1 represents H or -Z1-NH2 and Z1 represents an alkyl, a cycloalkyl or an aryl having up to 15 carbon atoms and R2 represents H or -Z2-NH2 and Z2 represents an alkyl, a cycloalkyl or an aryl having up to 15 carbon atoms, it being possible for R1 and R2 to be identical or different. The tie resin may also be a copolymer having polyamide blocks and polyether blocks, the polyamide blocks resulting from condensation of at least one diacid and at least one diamine of formula (1). The invention also relates to a structure comprising a fluoropolymer layer, the tie layer and a substrate layer, respectively, as well as to a structure comprising a tie layer, respectively. This structure may be placed between two substrate layers and may be in the form of a sheet, film, profile or tube. It is particularly useful in the form of a tube for transporting gasoline between the tank and the injection device in motor-vehicle engines.
摘要翻译： 由含氟聚合物层制成的结构，其直接连接到其一侧，基于由至少一种二酸和至少一种下式（1）的二胺缩合而得到的聚酰胺：其中R 1表示H或-Z 1 -NH 2，Z 1表示烷基，环烷基或具有至多15个碳原子的芳基，R 2表示H 或-Z 2 -NH 2，Z 2代表具有至多15个碳原子的烷基，环烷基或芳基，R 1和R 2可以是 相同或不同。 粘结树脂还可以是具有聚酰胺嵌段和聚醚嵌段的共聚物，由至少一种二酸和至少一种式（1）的二胺的缩合产生的聚酰胺嵌段。 本发明还涉及分别包括含氟聚合物层，连接层和基底层的结构，以及分别包括粘结层的结构。 该结构可以放置在两个基底层之间，并且可以是片，膜，轮廓或管的形式。 在汽车发动机中的罐和注射装置之间输送汽油的管子的形式特别有用。
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7.发明申请Multilayer structure based on polyamides and on a tie layer made of a copolyamide blend 失效基于聚酰胺和由共聚酰胺共混物制成的粘结层的多层结构公开(公告)号：US20050112390A1
公开(公告)日：2005-05-26
申请号：US10978408
申请日：2004-11-02
申请人： Christophe Lacroix
发明人： Christophe Lacroix
CPC分类号： B32B27/08 , B32B1/08 , B32B7/10 , B32B27/30 , B32B27/34 , F16L11/04 , F16L2011/047 , Y10T428/31725 , Y10T428/31728 , Y10T428/31732 , Y10T428/31743
摘要： A multilayer structure based on polyamides, comprising: a first layer (1) formed from a polyamide P1 or from a blend of a polyamide P1 and a polyolefin PO1 having a P1 polyamide matrix, optionally, a layer (2a) formed from EVOH; a layer (2) formed from a blend of PA-6/12 copolyamides, one comprising by weight more 6 than 12 and the other more 12 than 6; a layer (3) formed from a polyamide P3, it being possible for P1 and P3 to be identical or different, the layers (1), (2), (2a) and (3) being successive and adhering to one another in their respective contact regions.
摘要翻译： 一种基于聚酰胺的多层结构，包括：由聚酰胺P 1形成的第一层（1）或由聚酰胺P 1和聚烯烃PO
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公开(公告)号：US20050084685A1
公开(公告)日：2005-04-21
申请号：US10967587
申请日：2004-10-18
IPC分类号： A63C5/00 , A63C5/12 , B29C41/22 , B32B27/08 , B32B27/34 , B32B27/40 , B44C1/10 , B44C1/17 , B32B31/00
CPC分类号： B32B27/08 , A43B1/0027 , A63C5/003 , A63C5/12 , B32B27/18 , B32B27/34 , B32B27/40 , B32B2307/412 , B32B2437/02 , B44C1/105 , B44C1/1716 , Y10T428/31551 , Y10T428/31562 , Y10T428/31725 , Y10T428/31739
摘要： The present invention relates to a multilayer structure comprising a transparent polyamide-based layer and a layer based on a thermoplastic polyurethane (TPU). The invention also relates to a decorated article consisting of an object to which the above structure has been bonded, the polyamide layer being on the outside. According to another embodiment, the polyamide/TPU structures may be bonded to a polyurethane foam or to a polyurethane resin. It is also possible to overmould the polyurethane foam or the polyurethane resin to the polyamide/TPU structure placed in a mould, the polyamide layer being adjacent to the mould wall. The structure obtained is useful, for example for making skis or sports shoes. The invention also relates to these structures. Advantageously, the polyamide layer is semicrystalline. Advantageously, the TPU layer is transparent. Each of the layers may be formed from several layers.
摘要翻译： 本发明涉及包含透明聚酰胺基层和基于热塑性聚氨酯（TPU）的层的多层结构。 本发明还涉及一种由上述结构粘合的物体组成的装饰物品，聚酰胺层位于外侧。 根据另一个实施方案，聚酰胺/ TPU结构可以结合到聚氨酯泡沫或聚氨酯树脂上。 也可以将聚氨酯泡沫或聚氨酯树脂过模制到放置在模具中的聚酰胺/ TPU结构，聚酰胺层与模具壁相邻。 获得的结构是有用的，例如用于制造滑雪板或运动鞋。 本发明还涉及这些结构。 有利地，聚酰胺层是半结晶的。 有利地，TPU层是透明的。 每个层可以由几层形成。
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公开(公告)号：US06809151B1
公开(公告)日：2004-10-26
申请号：US09718426
申请日：2000-11-24
IPC分类号： C08G6348
CPC分类号： C08L67/02 , C08L2666/02
摘要： The present invention relates to the thermoplastic polyesters, which comprise, by weight (i) a thermoplastic polyester; (ii) an impact modifier comprising: (a) a core-shelf copolymer (A); (b) an ethylene copolymer (B) chosen from ethylene-unsaturated carboxylic acid anhydride copolymers (B1), ethylene-saturated epoxide copolymers (B2) and blends thereof; (iii) the (B)/(A) ratio being between 90/10 and 25/75 for proportions of impact modifier between 2 and 40% in 98 to 60% of polyester, respectively; (iv) the (B)/(A) ratio being between 25/75 and 10/90 for proportions of impact modifier between 18 and 40% in 82 to 60% of polyester, respectively. It is particularly useful for PET and PBT.
摘要翻译： 本发明涉及热塑性聚酯，其包含（i）热塑性聚酯;（ii）抗冲改性剂，其包含：（a）核 - 架共聚物（A）;（b）乙烯共聚物（B） 选自乙烯 - 不饱和羧酸酐共聚物（B1），乙烯 - 饱和环氧化物共聚物（B2）及其共混物;（iii）（B）/（A）的比例为90/10至25/75， 改性剂在98至60％的聚酯中分别为2至40％;（iv）（B）/（A）比为25/75至10/90，冲击改性剂的比例为82至82％ 60％的聚酯。 它对PET和PBT特别有用。
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10.发明授权公开(公告)号：US06759480B1
公开(公告)日：2004-07-06
申请号：US09670121
申请日：2000-09-26
IPC分类号： C08L2904
CPC分类号： C08L101/00 , C08L23/08 , C08L27/12 , C08L29/04 , C08L33/12 , C08L61/00 , C08L67/00 , C08L69/00 , C08L73/00 , C08L75/04 , C08L77/00 , C08L77/02 , C08L77/06 , C08L2666/20 , C08L2666/04 , C08L23/00 , C08L33/00
摘要： The invention relates to thermoplastic compositions comprising: −40 to 97 parts of a thermoplastic polymer (M) forming a matrix, chosen from polyamides, polyamide block copolymers, fluoro polymers, polycarbonate, styrene resins, PMMA, thermoplastic polyurethanes (TPU), copolymers containing polyester blocks and polyether blocks, polycarbonate-polyester alloys, polyketones, PVC and ethylene-vinyl alcohol copolymers (EVOH), −60 to 3 parts of (B) comprising: either an ethylene-alkyl (meth)acrylate copolymer (B1), the alkyl having at least 5 carbon atoms, which copolymer (B1) carries a functional group or a blend of an ethylene-alkyl (meth)acrylate copolymer (B2), the alkyl having at least 5 carbon atoms, which copolymer (B2) does not carry a functional group, and of an impact modifier which carries a functional group.
摘要翻译： 本发明涉及热塑性组合物，其包含：-40至97份形成基质的热塑性聚合物（M），其选自聚酰胺，聚酰胺嵌段共聚物，氟聚合物，聚碳酸酯，苯乙烯树脂，PMMA，热塑性聚氨酯（TPU），含有 聚酯嵌段和聚醚嵌段，聚碳酸酯 - 聚酯合金，聚酮，PVC和乙烯 - 乙烯醇共聚物（EVOH）， - 60〜3份（B），包括：乙烯 - （甲基）丙烯酸烷基酯共聚物（B1） 具有至少5个碳原子的烷基，该共聚物（B1）携带官能团或乙烯 - （甲基）丙烯酸烷基酯共聚物（B2），该共聚物（B2）不携带的具有至少5个碳原子的烷基的共混物 官能团和带有官能团的抗冲改性剂。
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