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公开(公告)号：US20070175469A1
公开(公告)日：2007-08-02
申请号：US11565280
申请日：2006-11-30
IPC分类号： A61M11/00
CPC分类号： A61M15/0065 , A61M11/001 , A61M15/0071 , A61M15/008 , A61M15/009 , B05B1/044 , B05B1/14 , B05B1/26 , B05B11/308 , B65D83/54
摘要： A dispensing device dispenses a liquid, in particular containing or formed of a drug, as a fine spray, that has a high fraction of small particles achieved by using a duct or slit having a flat cross section. Additionally or alternatively, the nozzle or duct has at least one sharp change in cross section and/or alternate sections with large and small cross-sectional areas.
摘要翻译： 分配装置将具有包含或由药物形成的液体作为细小喷雾分配，其具有通过使用具有平坦横截面的管道或狭缝获得的大部分小颗粒。 附加地或替代地，喷嘴或管道具有至少一个横截面的急剧变化和/或具有大的和小的横截面积的交替部分。
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公开(公告)号：US20080001008A1
公开(公告)日：2008-01-03
申请号：US11749263
申请日：2007-05-16
申请人： Ralf Thoemmes , Timo Von Brunn , Marc Rohrschneider , Stephen Dunne , Anke Klaer
发明人： Ralf Thoemmes , Timo Von Brunn , Marc Rohrschneider , Stephen Dunne , Anke Klaer
CPC分类号： A61M15/009 , A61M11/006 , A61M11/02 , A61M15/00 , A61M15/0026 , A61M15/0045 , A61M15/0048 , A61M15/005 , A61M15/0061 , A61M15/0075 , A61M15/0083 , A61M2202/064
摘要： An atomizer, a reservoir and a method are proposed for the delivery and in particular, the atomization of a formulation, particularly a powder. A pump and a spring are arranged inside the annular reservoir, the pump and the spring being moveable radially and in a sliding manner. The pump is actuated by the spring to put air under pressure for discharging powder from the reservoir. The reservoir comprises receptacles or cavities, each of which has an insert with a respective dose of the formulation. The receptacles are constructed as separate parts and/or arranged on a common or annular carrier and/or are sealed separately and/or on its outer circumferential periphery. The spring is tensioned and the air is sucked into the pump. Then, the next receptacle and a connecting element are aligned relative to each other. Finally, the aligned receptacle is pierced by the connecting element for supplying the air.
摘要翻译： 提出了雾化器，储存器和方法用于递送，特别是制剂的雾化，特别是粉末。 泵和弹簧布置在环形容器内部，泵和弹簧可以径向和滑动地移动。 泵由弹簧致动，以将空气压在压力下，从储存器排出粉末。 储存器包括插座或空腔，每个插座具有具有相应剂量的制剂的插入物。 容器被构造为分开的部件和/或布置在共同的或环形的载体上和/或分别密封和/或在其外圆周周边上密封。 弹簧张紧，空气被吸入泵中。 然后，下一个插座和连接元件相对于彼此对准。 最后，对准的容器被用于供应空气的连接元件刺穿。
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公开(公告)号：US20070272763A1
公开(公告)日：2007-11-29
申请号：US11576853
申请日：2005-10-06
申请人： Stephen Dunne , Marc Rohrschneider , Achim Moser
发明人： Stephen Dunne , Marc Rohrschneider , Achim Moser
CPC分类号： A61M15/0028 , A61M11/001 , A61M11/002 , A61M11/02 , A61M15/0003 , A61M15/002 , A61M15/0031 , A61M15/0033 , A61M15/0045 , A61M15/0048 , A61M15/0051 , A61M2202/064 , A61M2205/073 , A61M2205/8225 , A61M2206/16
摘要： A dispensing device, a storage device and a method for dispensing powder in which powder is dispensed through a duct with a flat cross section to de-agglomerate the powder and to generate a spray with fine particle size. A storage chamber for the powder may be closed by a bursting element which is burst by pressurized gas for discharging the powder, the gas pressure reaching or exceeding a peak value before the bursting element bursts so that the powder is dispensed at a lower gas pressure. The powder may be forced through the duct by a gas pressure of less than 300 kPa to de-agglomerate the powder and/or to generate the spray. The storage device can have multiple storage chambers and associated ducts or nozzles, so that each dose of powder can be dispensed through a separate duct or nozzle.
摘要翻译： 分配装置，存储装置和分配粉末的方法，其中通过具有平坦横截面的管道分配粉末，以使粉末解聚并产生具有细粒度的喷雾。 用于粉末的储存室可以由爆破元件封闭，该破裂元件通过用于排出粉末的加压气体爆裂，气体压力在爆裂元件爆发之前达到或超过峰值，使得粉末以较低的气体压力被分配。 可以通过小于300kPa的气体压力将粉末强制通过管道，以使粉末脱团解和/或产生喷雾。 存储装置可以具有多个存储室和相关联的管道或喷嘴，使得可以通过单独的管道或喷嘴分配每一剂量的粉末。
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公开(公告)号：US07681811B2
公开(公告)日：2010-03-23
申请号：US11764248
申请日：2007-06-18
IPC分类号： A62C2/08
CPC分类号： B05B11/3091 , A61M11/00 , A61M15/0065 , B05B1/26 , B05B15/65
摘要： The invention relates to a nozzle system for a delivery device for liquids, wherein the nozzle system comprises a nozzle and a device which fixes the nozzle in the delivery device. The delivery device, an atomizer, has a liquid reservoir from which a liquid is forced through the nozzle under pressure. The nozzle fixing means may itself be secured by a second fixing, e.g., in the form of a check nut, or the fixing may itself be a check nut. According to the invention the fixing means on the nozzle outlet side has a specific geometry which minimizes the proportion of dispensed liquid deposited on the fixing means. Preferably, the present invention is part of a propellant-free device for nebulizing pharmaceutical liquids.
摘要翻译： 本发明涉及一种用于液体输送装置的喷嘴系统，其中喷嘴系统包括喷嘴和将喷嘴固定在输送装置中的装置。 输送装置，雾化器，具有液体储存器，液体在压力下被迫使其通过喷嘴。 喷嘴固定装置本身可以通过例如以止回螺母的形式的第二固定来固定，或者固定本身可以是止回螺母。 根据本发明，喷嘴出口侧上的固定装置具有特定的几何形状，其使沉积在固定装置上的分配液体的比例最小化。 优选地，本发明是用于雾化药物液体的无推进剂的装置的一部分。
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公开(公告)号：US07284713B2
公开(公告)日：2007-10-23
申请号：US10982991
申请日：2004-11-05
CPC分类号： B05B11/3091 , A61M11/00 , A61M15/0065 , B05B1/26 , B05B15/65
摘要： The invention relates to a nozzle system for a delivery device for liquids, wherein the nozzle system comprises a nozzle and a device which fixes the nozzle in the delivery device. The delivery device, an atomiser, has a liquid reservoir from which a liquid is forced through the nozzle under pressure. The nozzle fixing means may itself be secured by a second fixing, e.g., in the form of a check nut, or the fixing may itself be a check nut. According to the invention the fixing means on the nozzle outlet side has a specific geometry which minimizes the proportion of dispensed liquid deposited on the fixing means.Preferably, the present invention is part of a propellant-free device for nebulizing pharmaceutical liquids.
摘要翻译： 本发明涉及一种用于液体输送装置的喷嘴系统，其中喷嘴系统包括喷嘴和将喷嘴固定在输送装置中的装置。 输送装置，雾化器，具有液体储存器，液体在压力下被迫使其通过喷嘴。 喷嘴固定装置本身可以通过例如以止回螺母的形式的第二固定来固定，或者固定本身可以是止回螺母。 根据本发明，喷嘴出口侧上的固定装置具有特定的几何形状，其使沉积在固定装置上的分配液体的比例最小化。 优选地，本发明是用于雾化药物液体的无推进剂的装置的一部分。
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公开(公告)号：US07708011B2
公开(公告)日：2010-05-04
申请号：US10669576
申请日：2003-09-24
CPC分类号： A61M15/0028 , A61M15/0015 , A61M15/0048 , A61M15/005 , A61M15/0051 , A61M2016/0021 , A61M2202/064
摘要： A dry powder inhaler (1) is to be made available, with which a particle size and particle size distribution preferred for inhalation are to be achieved and by means of which as high a line particle fraction as possible is to be realized. This is achieved by means of a dry powder inhaler (1 ) that is characterized in that provided in the inhaler (1) is a nozzle (10) through which the aerosol (9) flows before leaving the inhaler (1).
摘要翻译： 要获得干粉吸入器（1），要实现吸入剂优选的粒度和粒度分布，并且通过该干粉吸入器可以实现尽可能高的线粒子分数。 这通过干粉吸入器（1）来实现，其特征在于，吸入器（1）中设置有喷嘴（10），喷雾器（9）在离开吸入器（1）之前流过其中。
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7.发明申请Apparatus For The Dispensing Of Liquids, Container Cartridge Suitable For This, And System Comprising The Apparatus For The Dispensing Of Liquids And The Container Cartridge 审中-公开用于液体分配的装置，适用于此的容器盒，以及包括用于液体和容器盒的分配的装置的系统公开(公告)号：US20100096408A1
公开(公告)日：2010-04-22
申请号：US12645133
申请日：2009-12-22
申请人： Joerg Schiewe , Gilbert Wuttke , Bernd Zierenberg , Stephen Dunne , Horst Wergen
发明人： Joerg Schiewe , Gilbert Wuttke , Bernd Zierenberg , Stephen Dunne , Horst Wergen
IPC分类号： B67D1/00
CPC分类号： B05B11/0054 , A61M15/0028 , A61M15/0081 , B05B11/02 , B05B11/3091
摘要： The present invention relates to a propellant-gas-free apparatus for the dispensing of liquids, a container cartridge suitable for this for storing the liquid and the ensemble comprising both. The invention comprises a device for the exertion of pressure and for accommodating a container cartridge and a container cartridge in which the dispensing facility is integrated.
摘要翻译： 本发明涉及一种用于分配液体的无气体推进剂装置，适用于储存液体的容器盒和包括两者的组合物。 本发明包括用于施加压力并用于容纳集装箱的装置和其中分配设备被集成的容器盒。
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公开(公告)号：US20050077392A1
公开(公告)日：2005-04-14
申请号：US10982991
申请日：2004-11-05
IPC分类号： A61M11/00 , B05B1/02 , B05B1/26 , B05B11/00 , B05B15/06 , A62C31/02 , A62C5/00 , B05B7/04 , F23D11/36
CPC分类号： B05B11/3091 , A61M11/00 , A61M15/0065 , B05B1/26 , B05B15/65
摘要： The invention relates to a nozzle system for a delivery device for liquids, wherein the nozzle system comprises a nozzle and a device which fixes the nozzle in the delivery device. The delivery device, an atomiser, has a liquid reservoir from which a liquid is forced through the nozzle under pressure. The nozzle fixing means may itself be secured by a second fixing, e.g., in the form of a check nut, or the fixing may itself be a check nut. According to the invention the fixing means on the nozzle outlet side has a specific geometry which minimises the proportion of dispensed liquid deposited on the fixing means. Preferably, the present invention is part of a propellant-free device for nebulising pharmaceutical liquids.
摘要翻译： 本发明涉及一种用于液体输送装置的喷嘴系统，其中喷嘴系统包括喷嘴和将喷嘴固定在输送装置中的装置。 输送装置，雾化器，具有液体储存器，液体在压力下被迫使其通过喷嘴。 喷嘴固定装置本身可以通过例如以止回螺母的形式的第二固定来固定，或者固定本身可以是止回螺母。 根据本发明，喷嘴出口侧上的固定装置具有特定的几何形状，其使沉积在固定装置上的分配液体的比例最小化。 优选地，本发明是用于雾化药物液体的无推进剂的装置的一部分。
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公开(公告)号：US20050263151A1
公开(公告)日：2005-12-01
申请号：US11072374
申请日：2005-03-04
申请人： Dieter Hochrainer , Stephen Dunne , Georg Boeck , Joerg Schiewe
发明人： Dieter Hochrainer , Stephen Dunne , Georg Boeck , Joerg Schiewe
CPC分类号： A61M15/0028 , A61M15/005 , A61M15/009 , A61M2202/064
摘要： The invention relates to a powder inhaler (1) with mouthpiece (2) for dispersing pharmaceutical medicament formulations, which comprises an auxiliary energy source in the form of a pressure medium system (3), having a device for supplying (6) a powder formulation (7), while on activation of the pressure medium system a gaseous pressure medium (8) released by the pressure medium system (3) forms an aerosol (9) with the powder formulation (7) such that the powder particles are present in the gaseous pressure medium (8) in dispersed form. This is achieved by means of a powder inhaler (1) comprising a multi-channel nozzle, the channels of which are inclined to one another at an angle such that the aerosol jets flowing through them meet one another downstream behind the nozzle (10).
摘要翻译： 本发明涉及一种具有用于分散药物制剂的吸嘴（2）的粉末吸入器（1），其包括压力介质系统（3）形式的辅助能量源，其具有用于供应（6）粉末制剂 （7），在压力介质系统激活时，由压力介质系统（3）释放的气体压力介质（8）与粉末制剂（7）形成气溶胶（9），使得粉末颗粒存在于 分散形式的气体压力介质（8）。 这通过包括多通道喷嘴的粉末吸入器（1）来实现，该多通道喷嘴的通道以一定角度彼此倾斜，使得流过它们的气溶胶喷流在喷嘴（10）的下游相交。
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10.发明授权Process for treating an engine exhaust stream employing a catalyst, an adsorbent bed and a turbocharger 失效使用催化剂，吸附床和涡轮增压器处理发动机废气流的方法
公开(公告)号：US5142864A
公开(公告)日：1992-09-01
申请号：US767590
申请日：1991-09-30
申请人： Stephen Dunne
发明人： Stephen Dunne
CPC分类号： B01D53/9481 , F01N13/009 , F01N3/0835 , F01N3/0878 , F01N2240/18 , F01N2250/12 , F01N2370/24 , F01N2410/12 , F01N3/20 , Y02T10/20
摘要： This invention relates to a process for minimizing hydrocarbon emissions from the exhaust streams of engines when the engines are first started, i.e., cold start. The process involves sequentially flowing the engine exhaust stream, which typically contains hydrocarbons, carbon monoxide and nitrogen oxide pollutants over a catalyst, the turbine side of a turbocharger and an adsorbent bed before discharging it into the atmosphere. The initial low temperature of the exhaust stream necessitates the use of the adsorbent bed. When the adsorbent bed (containing one or more molecular sieve beds) warms up (about 150.degree. C. to about 200.degree. C.), the majority of the exhaust stream is diverted around the adsorbent bed, while a minor portion is used to desorb the hydrocarbons adsorbed on the adsorbent bed and flowing these hydrocarbons through the compressor side of the turbocharger and then into the engine exhaust stream in front of the catalyst. When all the hydrocarbons are desorbed, the adsorbent bed is completely bypassed. The turbocharger lowers the temperature of the exhaust stream allowing hydrocarbons to be adsorbed for a longer period of time. The molecular sieves used in the invention are those that: 1) have a framework Si:Al ratio of at least 2.4; 2) are hydrothermally stable and 3) have a hydrocarbon selectivity greater than 1.
摘要翻译： 本发明涉及当发动机首先起动时，即冷启动时最小化来自发动机排气流的碳氢化合物排放的方法。 该方法包括在将催化剂，涡轮增压器的涡轮机侧和吸附剂床排放到大气中之前，顺序地流动发动机废气流，其通常包含烃，一氧化碳和氮氧化物污染物。 排气流的初始低温需要使用吸附剂床。 当吸附床（含有一个或多个分子筛床）加热（约150℃至约200℃）时，大部分排气流围绕吸附剂床转向，而较小部分用于解吸 吸附在吸附剂床上的烃并将这些烃流经涡轮增压器的压缩机侧，然后进入催化剂前面的发动机排气流中。 当所有的烃被解吸时，吸附剂床被完全绕过。 涡轮增压器降低排气流的温度，使得烃更长时间的吸附。 本发明中使用的分子筛是：1）具有至少2.4的骨架Si：Al比; 2）水热稳定，3）烃选择性大于1。
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