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    USE OF SUBSTITUTED METHOXYALKOXYPHENYLALKYL DERIVATIVES AS PRESERVATIVE, PRESERVING METHOD, COMPOUNDS AND COMPOSITION
    2.
    发明申请
    USE OF SUBSTITUTED METHOXYALKOXYPHENYLALKYL DERIVATIVES AS PRESERVATIVE, PRESERVING METHOD, COMPOUNDS AND COMPOSITION 有权
    作为保存，保存方法，化合物和组合物的替代的甲氧基甲基戊烯衍生物的使用

    公开(公告)号：US20130230473A1

    公开(公告)日：2013-09-05

    申请号：US13824172

    申请日：2011-10-06

    Applicant: Maria Dalko ,  Laurent Gilbert

    Inventor： Maria Dalko ,  Laurent Gilbert

    IPC: A61K8/35 ,  A61Q19/04 ,  A61Q17/04 ,  A61Q19/00 ,  C07C49/255 ,  A61Q5/00

    CPC classification number: A61K8/35 ,  A61K8/34 ,  A61K8/347 ,  A61K9/0014 ,  A61K47/08 ,  A61K2800/524 ,  A61Q5/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/002 ,  A61Q19/04 ,  C07C43/23 ,  C07C49/255

    Abstract: The present invention relates to the use as a preserving agent, in particular in cosmetic or dermatological composition, of at least one compound of formula (I): in which:—X represents ═O or —OH;—R1 represents a hydrogen atom or a methyl;—R2 represents a hydrogen atom, a methyl or an ethyl;—R3 represents a C1-C12, saturated or unsaturated, linear hydrocarbon-based radical, optionally substituted with a hydroxyl group (OH); with the exclusion of the compound of formula (I) in which X represents ═O, R1=methyl, R2=H and R3=—(CH2)6—CH3. The invention also relates to certain novel compounds and to the cosmetic or dermatological compositions comprising same.

    Abstract translation: 本发明涉及至少一种式（I）化合物的防腐剂，特别是化妆品或皮肤病学组合物的用途：其中：-X表示= O或-OH; -R1表示氢原子或 甲基; -R 2表示氢原子，甲基或乙基; -R 3表示任选被羟基（OH）取代的C 1 -C 12饱和或不饱和直链烃基自由基。 排除其中X表示= O，R 1 =甲基，R 2 = H和R 3 = - （CH 2）6 -CH 3的式（I）化合物。 本发明还涉及某些新化合物和包含其的化妆品或皮肤病学组合物。

    Compositions comprising jasmonic acid derivatives and use of these derivatives
    4.
    发明授权
    Compositions comprising jasmonic acid derivatives and use of these derivatives 有权
    包含茉莉酸衍生物的组合物和这些衍生物的用途

    公开(公告)号：US08603502B2

    公开(公告)日：2013-12-10

    申请号：US10356551

    申请日：2003-02-03

    Applicant: Christophe Boulle ,  Maria Dalko ,  Jean-Luc Leveque ,  Lucie Simonetti

    Inventor： Christophe Boulle ,  Maria Dalko ,  Jean-Luc Leveque ,  Lucie Simonetti

    IPC: A61K31/557

    CPC classification number: C07C69/732 ,  A61K8/345 ,  A61K8/365 ,  A61K8/44 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/08 ,  C07C35/06 ,  C07C59/11 ,  C07C59/46 ,  C07C69/675 ,  C07C2601/08

    Abstract: Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: R1 is a radical chosen from —COOR′, —CONR′R″, —CH2OR′, —COR′, —CH2R′, —SO2OR′, —PO3R′R″ and —NHR′, wherein R′ and R″, which may be identical or different, are defined herein; R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR′″, —OCOR′″, —SR′″, —SCOR′″, NR′″R″″, —NHCOR′″, halogen, —CN, —COOR′″ and —COR′″, wherein R′″ and R″″, which may be identical or different, are defined herein, as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.

    Abstract translation: 包含式（I）化合物及其相应盐的化妆品或药物组合物：其中：R1为选自-COOR'，-CONR'R“，-CHOOR'，-COR'，-CH2R'，-SO2OR的基团 '，-PO 3 R'R“和-NHR'，其中R'和R”可以相同或不同，在本文中定义; R 2选自包含1至18个碳原子的饱和和不饱和的，直链的，支链的和环状的烃基，其任选被1-5个相同或不同的选自-OR“，-OCOR” - ， - SR“'，-SCOR''，NR”'R“'， - NHCOR''，卤素，-CN，-COOR”和-COR“，其中R”'和 R“”可以相同或不同，并且这些化合物的用途，例如促进皮肤脱屑，刺激表皮更新和/或抵抗皮肤老化的迹象。

    USE OF NOVEL AMINO ACID DERIVATIVES AS AGENTS FOR TREATING HUMAN PERSPIRATION, AND COMPOSITIONS CONTAINING THEM
    5.
    发明申请
    USE OF NOVEL AMINO ACID DERIVATIVES AS AGENTS FOR TREATING HUMAN PERSPIRATION, AND COMPOSITIONS CONTAINING THEM 失效
    使用新型氨基酸衍生物作为治疗人类兴奋剂的药剂，以及含有它们的组合物

    公开(公告)号：US20130164237A1

    公开(公告)日：2013-06-27

    申请号：US13704454

    申请日：2011-06-08

    Applicant: Maria Dalko ,  Julien Hitee ,  Thomas Delanne

    Inventor： Maria Dalko ,  Julien Hitee ,  Thomas Delanne

    IPC: C07K7/02 ,  A61Q15/00 ,  A61K8/64

    CPC classification number: C07K7/02 ,  A61K8/64 ,  A61Q15/00 ,  C07K7/06

    Abstract: The invention relates to the use, as an agent for treating human perspiration, in a cosmetic composition, of amino acid derivatives of formula (I) below: The invention also relates to a cosmetic process for treating perspiration and possibly the body odour associated with human perspiration, especially underarm odour. The invention also relates to novel amino acid derivatives of formula (II) that will be defined in detail hereinbelow, and to cosmetic or dermatological compositions containing them.

    Abstract translation: 本发明涉及在化妆品组合物中用作治疗人类出汗的药剂，以下式（I）的氨基酸衍生物的用途：本发明还涉及用于治疗汗水和可能的与人相关的体臭的美容方法 出汗，特别是腋臭。 本发明还涉及将在下文中详细定义的式（II）的新型氨基酸衍生物和含有它们的化妆品或皮肤病学组合物。

    DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS
    8.
    发明申请
    DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS 有权
    葡萄糖和维生素F的衍生物，包含其的组合物，使用和制备方法

    公开(公告)号：US20090149396A1

    公开(公告)日：2009-06-11

    申请号：US12370006

    申请日：2009-02-12

    Applicant: Jean-Francois Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    Inventor： Jean-Francois Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    IPC: A61K31/7024

    CPC classification number: C07H13/06 ,  A61K8/34 ,  A61K8/602 ,  A61K8/731 ,  A61K31/133 ,  A61K31/192 ,  A61K31/4412 ,  A61K31/7024 ,  A61K31/717 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q7/00 ,  C07H1/00 ,  C07H13/02 ,  Y10S514/88

    Abstract: An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and of at least one acid chosen from linoleic acid, oleic acid, palmitic acid and stearic acid, compositions, for example, cosmetic and pharmaceutical compositions, comprising this novel derivative, and their use for improving the condition of head hair and/or other hairs, and, for example, for reducing and/or impeding the loss of head hair and/or other hairs, and/or for inducing and/or stimulating hair growth, as well as a process for preparing O-acyl derivatives mainly in position 6 of glucose, comprising preparing a mixed anhydride by reacting a carboxylic acid with a trimethylacetyl halide, followed by reacting said mixed anhydride formed with glucose.

    Abstract translation: 衍生自葡萄糖的O-酰基产物可以通过葡萄糖和维生素F的部分或全部酯化获得，其包含葡萄糖和至少一种选自亚油酸，油酸的酸的酯，例如单酯的混合物 ，棕榈酸和硬脂酸，组合物，例如包含该新型衍生物的化妆品和药物组合物，以及它们用于改善头发和/或其它毛发的状况的用途，并且例如用于减少和/或阻碍 头发和/或其他毛发的丧失和/或用于诱导和/或刺激毛发生长的方法，以及主要在葡萄糖6位上制备O-酰基衍生物的方法，包括通过使羧酸 与三甲基乙酰卤反应，然后与形成的葡萄糖形成的混合酸酐反应。

    Cosmetic Process for Preventing or Treating the Signs of Skin Ageing or the Orange-Peel Appearance
    9.
    发明申请
    Cosmetic Process for Preventing or Treating the Signs of Skin Ageing or the Orange-Peel Appearance 审中-公开
    用于预防或治疗皮肤老化或橙皮外观的迹象的化妆过程

    公开(公告)号：US20090047224A1

    公开(公告)日：2009-02-19

    申请号：US10580230

    申请日：2004-11-08

    Applicant: Maria Dalko ,  Herve Pageon

    Inventor： Maria Dalko ,  Herve Pageon

    IPC: A61K8/49 ,  A61K31/4015 ,  A61K31/4025 ,  C07D207/444 ,  C07D407/10

    CPC classification number: C07D405/04 ,  A61K8/49 ,  A61K8/4913 ,  A61K8/69 ,  A61Q19/02 ,  A61Q19/06 ,  A61Q19/08 ,  C07D207/46 ,  C07D211/94

    Abstract: The present invention relates to the use of at least one compound capable of cleaving the diketone crosslinking bonds between two proteins, in a composition applied topically to the skin, as an agent for preventing or treating the signs of ageing of the skin or the orange-peel appearance. The above compound is preferably a N-hydroxy imide of formula (I). These N-hydroxy imides have inhibitory properties on the glycation of proteins and also antioxidant properties. The invention also relates to novel N-hydroxy imides included in formula (I) above.

    Abstract translation: 本发明涉及至少一种能够在两种蛋白质之间切割二酮交联键的化合物在局部施用于皮肤的组合物中的用途，作为用于预防或治疗皮肤老化迹象或橙 - 剥皮外观。 上述化合物优选为式（I）的N-羟基酰亚胺。 这些N-羟基酰亚胺对蛋白质的糖基化以及抗氧化性质具有抑制性。 本发明还涉及上述式（I）中所含的新型N-羟基酰亚胺。

    Cosmetic compositions comprising N-acylamino amides
    10.
    发明授权
    Cosmetic compositions comprising N-acylamino amides 有权
    包含N-酰基氨基酰胺的化妆品组合物

    公开(公告)号：US07419970B2

    公开(公告)日：2008-09-02

    申请号：US11102812

    申请日：2005-04-11

    Applicant: Maria Dalko ,  Yann Mahe ,  Lionel Breton

    Inventor： Maria Dalko ,  Yann Mahe ,  Lionel Breton

    IPC: A61K31/66

    CPC classification number: A61K8/44 ,  A61K8/69 ,  A61K38/00 ,  A61K2800/782 ,  A61Q5/00 ,  A61Q7/00 ,  A61Q19/08 ,  C07K5/06052 ,  C07K5/06191

    Abstract: The invention concerns novel compounds of the N-acylamino-amide family, compositions, in particular cosmetic or pharmaceutical, containing them, and their use for treating body or face skin ageing, whether chronobiologic or light-induced, and in particular skin ageing caused by decrease of skin elasticity and/or by collagen degradation in the structure of tissues.

    Abstract translation: 本发明涉及N-酰基氨基 - 酰胺家族的新化合物，包含它们的组合物，特别是化妆品或药物，以及它们用于治疗身体或面部皮肤老化，无论是时间生物学或光诱导的用途，特别是由 降低皮肤弹性和/或通过组织结构中的胶原蛋白降解。

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