公开(公告)号：US20080051671A1

公开(公告)日：2008-02-28

申请号：US11929007

申请日：2007-10-30

申请人： Thomas Broome ,  Anthony Vrba ,  Narin Anderson ,  Justin Crank ,  James Hansen ,  Horng-Ban Lin ,  Mark Smith

发明人： Thomas Broome ,  Anthony Vrba ,  Narin Anderson ,  Justin Crank ,  James Hansen ,  Horng-Ban Lin ,  Mark Smith

IPC分类号： A61B5/026

CPC分类号： A61B5/02158 ,  A61B5/02156 ,  A61F2/013

摘要： Devices and methods for monitoring the flow of blood through an intravascular device are disclosed. An apparatus for monitoring blood flow in accordance with an exemplary embodiment of the present invention includes an intravascular device coupled to an elongated member, a first sensor adapted to measure fluidic pressure proximal the intravascular device, a second sensor adapted to measure fluidic pressure distal the intravascular device, and a control unit for comparing the signals received from the first and second sensors to determine the pressure drop across the intravascular device.

摘要翻译： 公开了通过血管内装置监测血流的装置和方法。 根据本发明的示例性实施例的用于监测血流的装置包括联接到细长构件的血管内装置，适于测量血管内装置近侧的流体压力的第一传感器，适于测量血管内远端的流体压力的第二传感器 装置和控制单元，用于比较从第一和第二传感器接收的信号，以确定穿过血管内装置的压降。

公开(公告)号：US20050251198A1

公开(公告)日：2005-11-10

申请号：US10841684

申请日：2004-05-06

申请人： Mark Smith ,  James Hansen ,  Justin Crank ,  Narin Anderson ,  Horng-Ban Lin

发明人： Mark Smith ,  James Hansen ,  Justin Crank ,  Narin Anderson ,  Horng-Ban Lin

IPC分类号： A61F2/01 ,  B01D63/00 ,  B01D67/00 ,  B01D69/00 ,  A61M29/00

CPC分类号： B01D69/00 ,  A61F2/01 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/008 ,  B01D63/00 ,  B01D67/002 ,  B01D69/10 ,  B01D2323/24

摘要： Intravascular filters formed by a molding process can have a plurality of integrally formed apertures. A molding process can utilize a mold assembly that includes a mold having a mold surface and a die having a die surface. The mold assembly includes plurality of protrusions that extend from at least one of the mold surface and the die surface. A molten material is placed within a portion of the mold, and the die is then inserted into the mold such that the plurality of protrusions span a distance between the die surface and the mold surface. The molten material is allowed to solidify, thereby forming a filter membrane that includes a plurality of integrally formed apertures.

摘要翻译： 通过模制工艺形成的血管内过滤器可以具有多个一体形成的孔。 模制工艺可以利用包括具有模具表面的模具和具有模具表面的模具的模具组件。 模具组件包括从模具表面和模具表面中的至少一个延伸的多个突起。 将熔融材料放置在模具的一部分内，然后将模具插入模具中，使得多个突起跨过模具表面和模具表面之间的距离。 允许熔融材料固化，从而形成包括多个一体形成的孔的过滤膜。

公开(公告)号：US07163549B2

公开(公告)日：2007-01-16

申请号：US10364597

申请日：2003-02-11

申请人： Justin Crank ,  Narin Anderson ,  James G. Hansen ,  Horng-Ban Lin ,  Mark Smith ,  The Thomas Trinh Tran ,  Kinh-Luan D. Dao ,  Yem Chin ,  Sheng-Ping Zhong ,  James M. Anderson ,  Jeffrey H. Vogel

发明人： Justin Crank ,  Narin Anderson ,  James G. Hansen ,  Horng-Ban Lin ,  Mark Smith ,  The Thomas Trinh Tran ,  Kinh-Luan D. Dao ,  Yem Chin ,  Sheng-Ping Zhong ,  James M. Anderson ,  Jeffrey H. Vogel

IPC分类号： A61M29/00

CPC分类号： A61F2/013 ,  A61F2/01 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0067 ,  A61F2230/008

摘要： An embolic protection filter and method of making the same. An embolic protection filter may include a filter membrane or material having a plurality of holes. In some embodiments, the filter membrane may be manufactured by spray coating a filter material onto a forming member or spray mold.

摘要翻译： 栓塞保护过滤器及其制作方法。 栓塞保护过滤器可以包括具有多个孔的过滤膜或材料。 在一些实施例中，过滤膜可以通过将过滤材料喷涂到成形构件或喷雾模具上来制造。

公开(公告)号：US20050049690A1

公开(公告)日：2005-03-03

申请号：US10647619

申请日：2003-08-25

申请人： Dennis Boismier ,  Justin Crank

发明人： Dennis Boismier ,  Justin Crank

IPC分类号： A61F2/82 ,  C22F1/00 ,  A61F2/06

CPC分类号： C22F1/006 ,  A61F2/01 ,  A61F2/82 ,  A61F2250/0042 ,  Y10S148/902

摘要： Methods of selectively treating linear elastic materials to produce localized areas of superelasticity and/or shape-memory are disclosed. In an illustrative method, a linear elastic workpiece may be formed into a particular shape by cold-forming or other low-temperature process, and incorporated into a medical device such as an embolic protection filter, vena cava filter, stent or guidewire. A heat source may be used to apply thermal energy to selective areas of the workpiece, imparting superelasticity to the material.

摘要翻译： 公开了选择性处理线性弹性材料以产生超弹性和/或形状记忆的局部区域的方法。 在一个示例性的方法中，线性弹性工件可以通过冷成型或其它低温工艺形成特定形状，并且并入医疗装置如栓塞保护过滤器，腔静脉过滤器，支架或导丝中。 可以使用热源将热能施加到工件的选择区域，使材料具有超弹性。

公开(公告)号：US06893421B1

公开(公告)日：2005-05-17

申请号：US09635083

申请日：2000-08-08

申请人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

发明人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

IPC分类号： A61M25/00 ,  A61M5/178

CPC分类号： A61M25/0023 ,  A61M25/0021 ,  A61M25/0043 ,  A61M25/0084 ,  A61M2025/0089

摘要： A catheter shaft assembly is disclosed. A catheter shaft in accordance with the present invention comprises a first elongate shaft having an inner surface defining a lumen, a second elongate shaft slidingly disposed within the lumen of the first elongate shaft, at least one interstitial member disposed between the inner surface of the first elongate shaft and the outer surface of the second elongate shaft.

摘要翻译： 公开了一种导管轴组件。 根据本发明的导管轴包括具有限定内腔的内表面的第一细长轴，滑动地设置在第一细长轴的内腔内的第二细长轴，设置在第一细长轴的内表面之间的至少一个间隙构件 细长轴和第二细长轴的外表面。

公开(公告)号：US20050065474A1

公开(公告)日：2005-03-24

申请号：US10979233

申请日：2004-11-03

申请人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

发明人： Scott Larson ,  Justin Crank ,  Matthew Hawk ,  Bradley Slaker

IPC分类号： A61M25/00 ,  A61M5/178

CPC分类号： A61M25/0023 ,  A61M25/0021 ,  A61M25/0043 ,  A61M25/0084 ,  A61M2025/0089

摘要： A catheter assembly is disclosed. This assembly may include a first elongate member having an internal lumen and a distal portion, a second elongate member, slidable within the first elongate member, and a spacer positioned between the second elongate member and the first elongate member. In this example, the spacer may be positioned at bendable portions of the first elongate member and the second elongate member such that the spacer maintains a substantially uniform spacing between the second elongate member and the first elongate member when the first elongate member and the second elongate member are in a curved orientation.

摘要翻译： 公开了导管组件。 该组件可以包括具有内腔和远端部分的第一细长构件，在第一细长构件内可滑动的第二细长构件以及定位在第二细长构件和第一细长构件之间的间隔件。 在该示例中，间隔件可以定位在第一细长构件和第二细长构件的可弯曲部分处，使得当第一细长构件和第二细长构件与第二细长构件之间时，间隔件在第二细长构件和第一细长构件之间保持基本均匀的间隔 会员处于弯曲的方向。

公开(公告)号：US20050049523A1

公开(公告)日：2005-03-03

申请号：US10647613

申请日：2003-08-25

申请人： Justin Crank

发明人： Justin Crank

IPC分类号： A61B17/00 ,  A61B17/28 ,  A61M25/09 ,  A61B5/00

CPC分类号： A61M25/09 ,  A61B2017/00867 ,  A61B2017/2905 ,  A61M2025/09066 ,  A61M2025/09083 ,  A61M2025/09133

摘要： A medical device includes a coil having a longitudinal axis and a radial axis orthogonal to the longitudinal axis, formed from a wire. The wire includes a cross-section with a centroid, a moment of inertia with respect to an axis running through the centroid and parallel to the longitudinal axis of the coil, and a moment of inertia with respect to an axis running through the centroid and parallel to the radial axis of the coil. The moment of inertia with respect to an axis running through the centroid and parallel to the longitudinal axis of the coil is greater than the moment of inertia with respect to an axis running through the centroid and parallel to the radial axis of the coil.

摘要翻译： 一种医疗装置包括具有纵向轴线和与纵向轴线正交的径向轴线的线圈，该线圈由线形成。 导线包括具有质心的横截面，相对于穿过重心且平行于线圈的纵向轴线的轴的惯性矩，以及相对于穿过重心和平行的轴的惯性矩 到线圈的径向轴线。 相对于穿过重心且平行于线圈的纵轴的轴的惯性矩大于相对于穿过重心且平行于线圈的径向轴的轴的惯性矩。

公开(公告)号：US20060206093A1

公开(公告)日：2006-09-14

申请号：US11433584

申请日：2006-05-15

申请人： Justin Crank ,  Timothy Ostroot

发明人： Justin Crank ,  Timothy Ostroot

IPC分类号： A61B19/00

CPC分类号： A61M39/12 ,  A61M5/142 ,  A61M25/0097

摘要： A system for connecting a compatibility liner with a source of perishable therapeutic is provided. In one exemplary system for connecting a reservoir of perishable therapeutic with a lumen, a hollow hub having a first end and a second end is provided. The first end of the hollow hub, which contains a bond port, is in fluid communication with the second end. The second end of the hollow hub may contain a docking groove that is sized to couple a reservoir to it. The system also includes an inner hypo-tube having a proximal tip and an inner lumen. This inner lumen is lined with a therapeutic compatible lining and is in fluid communication with the second end of the hub through the proximal tip of the inner hypo-tube. The inner lining and the proximal tip in this system are configured to shield therapeutic ejected from the reservoir from contacting materials that can diminish the integrity of the therapeutic.

摘要翻译： 提供了一种用于将兼容性衬垫与易腐食品治疗源连接的系统。 在用于将易腐烂治疗剂的储存器与管腔连接的一个示例性系统中，提供了具有第一端和第二端的中空毂。 包含接合端口的中空毂的第一端与第二端流体连通。 中空轮毂的第二端可以包含一个对接凹槽，其尺寸设置成将储存器连接到其上。 该系统还包括具有近端和内腔的内管。 该内腔内衬有治疗相容的内衬，并通过内管的近端与流体通过毂的第二端流体连通。 该系统中的内衬和近侧尖端构造成屏蔽从储存器喷出的治疗物质可能会降低治疗剂完整性的接触材料。

公开(公告)号：US20050261667A1

公开(公告)日：2005-11-24

申请号：US11191053

申请日：2005-07-28

申请人： Justin Crank ,  Scott Larson ,  Timothy Mickley

发明人： Justin Crank ,  Scott Larson ,  Timothy Mickley

IPC分类号： A61J1/00 ,  A61J1/14 ,  A61M5/46 ,  A61M25/00 ,  A61M25/01 ,  A61M25/06 ,  A61M25/098

CPC分类号： A61M25/0068 ,  A61J1/1406 ,  A61M5/46 ,  A61M25/0074 ,  A61M25/0084 ,  A61M25/0108 ,  A61M25/0662 ,  A61M2025/0008 ,  A61M2025/0081 ,  A61M2025/0085 ,  A61M2025/0086 ,  A61M2025/0091 ,  A61M2205/19 ,  A61M2210/125

摘要： Devices and methods for performing improved percutaneous myocardial revascularization (PMR) procedures. One device includes a preassembled PMR drug delivery catheter and a drug neutralizing vial. The vial assembly allows prepping the PMR catheter by flushing drug through distal needle, and into a vial cavity where the drug is neutralized by a neutralizing agent. One set of devices includes needles having protrusions secured to the distal regions of drug delivery tubes. One needle has outward protruding barbs engaging the inner tube wall while another needle has outward threads which can screw into the tube inner wall. Radiopaque marker bands are also included in the present invention which are asymmetrically distributed on the catheter shaft, allowing a treating physician to determine under fluoroscopy whether the catheter distal region is pointed away or toward the treating physician, as well as determining whether the catheter distal region is rotated toward or away from the treating physician. PMR devices include catheters having dual injection needles, for both injecting a drug into the heart wall and a radiopaque contrast media to mark the already treated sites. One PMR injection device has multiple stops for allowing controlled, variable needle depth penetration with a single distal needle tip.

摘要翻译： 用于进行改善的经皮心肌血运重建（PMR）手术的装置和方法。 一个装置包括预组装的PMR药物递送导管和药物中和小瓶。 小瓶组件允许通过将药物通过远端针头冲洗并进入药物中和药物的小瓶腔中来准备PMR导管。 一组装置包括具有固定到药物输送管的远侧区域的突起的针。 一针具有与内管壁接合的向外突出的倒钩，而另一针具有能够拧入管内壁的外螺纹。 不透射线标记带也包括在本发明中，其不对称地分布在导管轴上，允许治疗医师在透视下确定导管远端区域是指尖的还是朝向治疗医师，以及确定导管远端区域 被转向或远离治疗医师。 PMR装置包括具有双注射针的导管，用于将药物注射到心脏壁中，以及不透射线造影剂以标记已经治疗的部位。 一个PMR注射装置具有多个止动件，用于允许用单个远端针尖进行可控的，可变的针深度穿透。

公开(公告)号：US07998130B2

公开(公告)日：2011-08-16

申请号：US12030503

申请日：2008-02-13

申请人： Justin Crank ,  Timothy Ostroot

发明人： Justin Crank ,  Timothy Ostroot

IPC分类号： A61M25/00

CPC分类号： A61M39/12 ,  A61M5/142 ,  A61M25/0097

摘要： A system for connecting a compatibility liner with a source of perishable therapeutic is provided. In one exemplary system for connecting a reservoir of perishable therapeutic with a lumen, a hollow hub having a first end and a second end is provided. The first end of the hollow hub, which contains a bond port, is in fluid communication with the second end. The second end of the hollow hub may contain a docking groove that is sized to couple a reservoir to it. The system also includes an inner hypo-tube having a proximal tip and an inner lumen. This inner lumen is lined with a therapeutic compatible lining and is in fluid communication with the second end of the hub through the proximal tip of the inner hypo-tube. The inner lining and the proximal tip in this system are configured to shield therapeutic ejected from the reservoir from contacting materials that can diminish the integrity of the therapeutic.

摘要翻译： 提供了一种用于将兼容性衬垫与易腐食品治疗源连接的系统。 在用于将易腐烂治疗剂的储存器与管腔连接的一个示例性系统中，提供了具有第一端和第二端的中空毂。 包含接合端口的中空毂的第一端与第二端流体连通。 中空轮毂的第二端可以包含一个对接凹槽，其尺寸设置成将储存器连接到其上。 该系统还包括具有近端和内腔的内管。 该内腔内衬有治疗相容的内衬，并通过内管的近端与流体通过毂的第二端流体连通。 该系统中的内衬和近侧尖端构造成屏蔽从储存器喷出的治疗物质可能会降低治疗剂完整性的接触材料。