摘要:
A method of monitoring the integrity of a fluid connection between first and second fluid containing systems based on at least one time-dependent measurement signal from a pressure sensor in the first fluid containing system. The pressure sensor detects first pulses originating from a first pulse generator in the first fluid containing system and second pulses originating from a second pulse generator in the second fluid containing system. A parameter value representing a distribution of signal values within a time window is calculated by analyzing the measurement signal in the time domain and/or by using information on the timing of the second pulses in the measurement signal. The parameter value may be calculated as a statistical dispersion measure of the signal values, or from matching the signal to a predicted temporal signal profile of the second pulse. The integrity of the fluid connection is determined from the parameter value.
摘要:
A device is provided for monitoring the integrity of a flow circuit in fluid communication with a receptacle. The flow circuit includes a pumping device for transferring fluid through the flow circuit. The device operates according to a monitoring method in which a pressure signal is received from a pressure sensor, the pressure signal being indicative of fluid pressure in the receptacle or the flow circuit. The pressure signal is then processed for detection of a beating signal. The beating signal manifests itself as an amplitude modulation of the pressure signal and is formed by interference between pressure waves generated by a pulse generator associated with the receptacle and pressure waves generated by the pumping device. The integrity of the flow circuit is determined based at least partly on the presence or absence of the beating signal. The device and the flow circuit may be part of an apparatus for extracorporeal blood treatment, and the method may be implemented as a computer program product.
摘要:
A surveillance device monitors the integrity of a fluid connection between first and second fluid containing systems based on at least one time-dependent measurement signal from a pressure sensor in the first fluid containing system. The first fluid containing system comprises a first pulse generator, and the second fluid containing system comprises a second pulse generator. The pressure sensor is arranged to detect first pulses originating from the first pulse generator and second pulses originating from the second pulse generator. The integrity of the fluid connection is determined based on the presence of second pulses in the measurement signal. The second pulses may be detected by analysing the measurement signal in the time domain and/or by using timing information indicative of the timing of the second pulses in said at least one measurement signal. The analysis may be based on a parameter value that represents a distribution of signal values within a time window of the measurement signal. The parameter value may be calculated as a statistical dispersion measure of the signal values, or may result from a matching of the signal values within the time window to a predicted temporal signal profile of a second pulse. The fluid connection may be established between a human blood system and an extracorporeal blood flow circuit.
摘要:
A device is provided for monitoring the integrity of a flow circuit in fluid communication with a receptacle. The flow circuit comprises a pumping device for transferring fluid through the flow circuit. The device operates according to a monitoring method in which a pressure signal is received from a pressure sensor, the pressure signal being indicative of fluid pressure in the receptacle or the flow circuit. The pressure signal is then processed for detection of a beating signal. The beating signal manifests itself as an amplitude modulation of the pressure signal and is formed by interference between pressure waves generated by a pulse generator associated with the receptacle and pressure waves generated by the pumping device. The integrity of the flow circuit is determined based at least partly on the presence or absence of the beating signal. The device and the flow circuit may be part of an apparatus for extracorporeal blood treatment, and the method may be implemented as a computer program product.
摘要:
A device is arranged to detect a configuration of withdrawal and return devices (1, 14, 111, 112, 211, 212, 702, 703, 802, 803) coupling an extracorporeal blood flow circuit (20) to a cardiovascular system of a subject. The device comprises a signal processor (29), which is configured to receive a primary measurement signal obtained by a primary pressure sensor (4a, 4b, 4c) in the extracorporeal blood flow circuit (20). The device is further configured to process the primary measurement signal for extraction of primary pressure data originating from a subject pulse generator (3′) in the cardiovascular system or extracorporeal blood flow circuit (20), the primary pressure data comprising at least a part of a first pulse from the subject pulse generator (3′). The device is also configured to calculate a parameter value from the primary pressure data and to determine the configuration based at least partly on the parameter value.
摘要:
A monitoring arrangement 100 is configured to predict a rapid syruptomatic drop in a subject's blood pressure, e.g. during a medical treatment or when operating aircraft. To this aim, a pulse shape parameter (pps) with respect to a peripheral body part (105) of the subject (P) is repeatedly registered by means of a pulse oximetry instrument (110) adapted to detect light response variations in blood vessels. A respective pulse magnitude measure is calculated based on each of a number of received pulse shape parameters (pps), and a statistical dispersion measure is calculated based on the thus-calculated pulse magnitude measure. It is investigated whether or not the statistical dispersion measure fulfils a decision criterion relative to a reference measure. An output signal (α) is generated if the decision criterion is found to be fulfilled.
摘要:
A device is configured to detect a fault condition in a fluid connection system between a first (e.g. extracorporeal blood circuit) and second (e.g. vascular system of a patient) fluid containing systems. The first and second fluid containing systems comprise a first and second pulse generator, respectively. A pressure sensor is arranged in the first fluid containing system to detect pulses originating from the first and second pulse generator. The device operates according to a detection method, by generating a time-dependent monitoring signal based on measurement data obtained from said at least one pressure sensor, such that the monitoring signal at least comprises one or more first pulses; processing (42) the monitoring signal to calculate a parameter value which is indicative of the shape of at least part of a first pulse in the monitoring signal, and evaluating (44) the parameter value for detection of the fault condition.
摘要:
A device monitors a blood path from a blood vessel access of a human subject through an extracorporeal blood processing apparatus and back to the blood vessel access. A pumping device in the blood path is operable to pump blood through the blood path from the blood withdrawal device to the blood return device. The monitoring device obtains pressure data from a pressure sensor arranged upstream of the pumping device in the blood path, and processes the pressure data for detection of a disruption of the blood path downstream of the pumping device, e.g. caused by VND (Venous Needle Dislodgement). The disruption is detected by evaluating presence/absence of cross-talk pulses at the pressure sensor, where the cross-talk pulses originate from one or more pulse generators in the extracorporeal blood processing apparatus and have propagated on a propagation path in a direction downstream of the pumping device through the blood return device, the blood vessel access and the blood withdrawal device to the pressure sensor.
摘要:
A device is arranged to detect a configuration of withdrawal and return devices (1, 14, 111, 112, 211, 212, 702, 703, 802, 803) coupling an extracorporeal blood flow circuit (20) to a cardiovascular system of a subject. The device comprises a signal processor (29), which is configured to receive a primary measurement signal obtained by a primary pressure sensor (4a, 4b, 4c) in the extracorporeal blood flow circuit (20). The device is further configured to process the primary measurement signal for extraction of primary pressure data originating from a subject pulse generator (3′) in the cardiovascular system or extracorporeal blood flow circuit (20), the primary pressure data comprising at least a part of a first pulse from the subject pulse generator (3′). The device is also configured to calculate a parameter value from the primary pressure data and to determine the configuration based at least partly on the parameter value.
摘要:
A device is configured to monitor a cardiovascular property of a subject. The device obtains measurement data from a primary pressure wave sensor arranged to detect pressure waves in an extracorporeal fluid circuit in fluid communication with the cardiovascular system of the subject. The device has a signal processor configured to generate a time-dependent monitoring signal based on the measurement data, such that the monitoring signal comprises a sequence of heart pulses, wherein each heart pulse represents a pressure wave originating from a heart beat in the subject; determine beat classification data for each heart pulse in the monitoring signal; and calculate, based at least partly on the beat classification data, a parameter value indicative of the cardiovascular property. The beat classification data may distinguish between heart pulses originating from normal heart beats and heart pulses originating from ectopic heart beats. The cardiovascular property may be an arterial status of the cardiovascular system, a degree of calcification in the cardiovascular system, a status of a blood vessel access used for connecting the extracorporeal fluid circuit to the cardiovascular system, a heart rate variability, a heart rate, a heart rate turbulence, an ectopic beat count, or an origin of ectopic beats. The device may be attached to or part of a dialysis machine.