MASS SPECTROMETER
    1.
    发明申请
    MASS SPECTROMETER 有权
    质谱仪

    公开(公告)号:US20090302209A1

    公开(公告)日:2009-12-10

    申请号:US12297481

    申请日:2007-04-30

    IPC分类号: H01J49/28

    摘要: An ion guide or mass analyser (2) is disclosed comprising a plurality of electrodes (2a) having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser (2). The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages (4) are applied to the electrodes (2a) of the ion guide or mass analyser (2) in order to urge ions along the length of the ion guides or mass analyser (2). The amplitude of the transient DC voltage (4) applied to the electrode (2a) may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser (2) in reverse order of their mass to charge ratio.

    摘要翻译: 公开了一种离子导向器或质量分析器(2),其包括具有孔的多个电极(2a),在使用中通过该孔具有离子。 在离子导向器或质量分析器(2)的出口处产生伪势垒。 伪势垒的幅度或深度与离子的质荷比成反比。 一个或多个瞬态DC电压(4)被施加到离子导向器或质量分析器(2)的电极(2a),以促使沿着离子导向器或质量分析器(2)的长度的离子。 施加到电极(2a)的瞬态直流电压(4)的振幅可以随时间增加,从而离子引导或质量分析器(2)以与其质荷比相反的顺序发射离子。

    Mass Spectrometer
    2.
    发明申请
    Mass Spectrometer 有权
    质谱仪

    公开(公告)号:US20070284521A1

    公开(公告)日:2007-12-13

    申请号:US10599572

    申请日:2005-04-04

    IPC分类号: H01J49/04 H01J49/40 H01J49/42

    CPC分类号: H01J49/06 Y10T436/24

    摘要: A mass spectrometer is disclosed comprising an ion beam attenuator which attenuates an ion beam repeatedly switching between a zero transmission mode of operation during a time period ΔT1 and a non-zero transmission mode of operation during a time period ΔT2. The degree of attenuation of the ion beam can be varied by varying the mark space ratio ΔT2/ΔT1. The ion beam attenuator may release ions in packets or pulses but the packets or pulses of ions may be converted into a continuous ion beam by a relatively high pressure ion guide or gas collision cell arranged downstream of the ion beam attenuator.

    摘要翻译: 公开了一种质谱仪,其包括离子束衰减器,该离子束衰减器在时间段ΔT1期间衰减离子束在时间段ΔT1内的零传输模式和在时间段ΔT2期间的非零传输模式之间重复切换。 SUB>。 离子束的衰减程度可以通过改变标记空间比DeltaT 2 /ΔT1 <1>而改变。 离子束衰减器可以以分组或脉冲的形式释放离子,但是离子束或脉冲可以通过布置在离子束衰减器下游的相对高压的离子导向器或气体碰撞元件转换为连续的离子束。

    Mass Spectrometer
    4.
    发明申请
    Mass Spectrometer 有权
    质谱仪

    公开(公告)号:US20070278397A1

    公开(公告)日:2007-12-06

    申请号:US11718213

    申请日:2005-11-03

    IPC分类号: H01J49/34 H01J49/42

    摘要: A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (4) and an ion guide (6) arranged downstream of the ion mobility spectrometer or separator (4). A plurality of axial potential wells are created in the ion guide (6) so that ions received from the ion mobility spectrometer or separator (4) become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator (4). The potential wells are translated along the length of the ion guide (6).

    摘要翻译: 公开了一种质谱仪,其包括离子迁移谱仪或分离器(4)和布置在离子迁移谱仪或分离器(4)的下游的离子导向器(6)。 在离子导向器(6)中产生多个轴向势阱,使得从离子迁移谱仪或分离器(4)接收的离子被限制在单独的轴向势阱中。 潜在的孔维持从离子迁移谱仪或分离器(4)接收的离子的保真度和/或组成。 潜在的井沿离子导向件(6)的长度平移。

    Mass spectrometer and method of mass spectrometry
    5.
    发明申请
    Mass spectrometer and method of mass spectrometry 审中-公开
    质谱仪和质谱法

    公开(公告)号:US20070023635A1

    公开(公告)日:2007-02-01

    申请号:US11513185

    申请日:2006-08-31

    IPC分类号: B01D59/44

    摘要: A mass spectrometer is disclosed comprising an ion mobility spectrometer in combination with a quadrupole mass filter which is scanned in synchronisation with the pulsing of ions into the ion mobility spectrometer thereby enabling ions having a particular charge state to be preferentially transmitted. Another embodiment replaces the quadrupole mass filter with an axial time of flight mass filter and an injection electrode.

    摘要翻译: 公开了一种质谱仪,其包括与四极质量过滤器组合的离子迁移谱仪,其与离子脉冲离子扫描到离子迁移谱仪中,从而使具有特定电荷状态的离子能够被优先传输。 另一实施例用轴向飞行时间质量过滤器和注入电极取代四极质量过滤器。

    Method of mass spectrometry
    6.
    发明申请
    Method of mass spectrometry 有权
    质谱法

    公开(公告)号:US20050118724A1

    公开(公告)日:2005-06-02

    申请号:US10498046

    申请日:2002-12-12

    IPC分类号: G01N24/00 H01J49/04

    CPC分类号: H01J49/062 Y10T436/24

    摘要: A method of mass spectrometry is disclosed wherein ions are trapped for a period of time T within an AC or RF ion guide maintained at a pressure P wherein the product P×T is at least 1 mbar-ms. The effect of trapping the ions according to a preferred embodiment is that singly charged ions which may, for example, comprise unwanted background ions are substantially lost from the trap whereas multiply charged analyte ions are maintained within the ion trap and can then be released for subsequent mass analysis.

    摘要翻译: 公开了一种质谱法,其中在产品PxT至少为1毫巴的压力下,在保持在压力P的AC或RF离子导向器内捕获离子一段时间T。 捕获根据优选实施方案的离子的效果是,可以例如包含不想要的背景离子的单电荷离子从捕获阱基本上丢失,而多电荷分析物离子保持在离子阱内,然后可以释放以用于随后的 质量分析。