Mass spectrometer and method of mass spectrometry
    1.
    发明申请
    Mass spectrometer and method of mass spectrometry 审中-公开
    质谱仪和质谱法

    公开(公告)号:US20070023635A1

    公开(公告)日:2007-02-01

    申请号:US11513185

    申请日:2006-08-31

    IPC分类号: B01D59/44

    摘要: A mass spectrometer is disclosed comprising an ion mobility spectrometer in combination with a quadrupole mass filter which is scanned in synchronisation with the pulsing of ions into the ion mobility spectrometer thereby enabling ions having a particular charge state to be preferentially transmitted. Another embodiment replaces the quadrupole mass filter with an axial time of flight mass filter and an injection electrode.

    摘要翻译: 公开了一种质谱仪,其包括与四极质量过滤器组合的离子迁移谱仪,其与离子脉冲离子扫描到离子迁移谱仪中,从而使具有特定电荷状态的离子能够被优先传输。 另一实施例用轴向飞行时间质量过滤器和注入电极取代四极质量过滤器。

    Method of mass spectrometry
    2.
    发明申请
    Method of mass spectrometry 有权
    质谱法

    公开(公告)号:US20050118724A1

    公开(公告)日:2005-06-02

    申请号:US10498046

    申请日:2002-12-12

    IPC分类号: G01N24/00 H01J49/04

    CPC分类号: H01J49/062 Y10T436/24

    摘要: A method of mass spectrometry is disclosed wherein ions are trapped for a period of time T within an AC or RF ion guide maintained at a pressure P wherein the product P×T is at least 1 mbar-ms. The effect of trapping the ions according to a preferred embodiment is that singly charged ions which may, for example, comprise unwanted background ions are substantially lost from the trap whereas multiply charged analyte ions are maintained within the ion trap and can then be released for subsequent mass analysis.

    摘要翻译: 公开了一种质谱法,其中在产品PxT至少为1毫巴的压力下,在保持在压力P的AC或RF离子导向器内捕获离子一段时间T。 捕获根据优选实施方案的离子的效果是,可以例如包含不想要的背景离子的单电荷离子从捕获阱基本上丢失,而多电荷分析物离子保持在离子阱内,然后可以释放以用于随后的 质量分析。

    Mass Spectrometer
    3.
    发明申请
    Mass Spectrometer 有权
    质谱仪

    公开(公告)号:US20070278397A1

    公开(公告)日:2007-12-06

    申请号:US11718213

    申请日:2005-11-03

    IPC分类号: H01J49/34 H01J49/42

    摘要: A mass spectrometer is disclosed comprising an ion mobility spectrometer or separator (4) and an ion guide (6) arranged downstream of the ion mobility spectrometer or separator (4). A plurality of axial potential wells are created in the ion guide (6) so that ions received from the ion mobility spectrometer or separator (4) become confined in separate axial potential wells. The potential wells maintain the fidelity and/or composition of ions received from the ion mobility spectrometer or separator (4). The potential wells are translated along the length of the ion guide (6).

    摘要翻译: 公开了一种质谱仪,其包括离子迁移谱仪或分离器(4)和布置在离子迁移谱仪或分离器(4)的下游的离子导向器(6)。 在离子导向器(6)中产生多个轴向势阱,使得从离子迁移谱仪或分离器(4)接收的离子被限制在单独的轴向势阱中。 潜在的孔维持从离子迁移谱仪或分离器(4)接收的离子的保真度和/或组成。 潜在的井沿离子导向件(6)的长度平移。

    Mass spectrometer
    4.
    发明申请
    Mass spectrometer 有权
    质谱仪

    公开(公告)号:US20070023638A1

    公开(公告)日:2007-02-01

    申请号:US11472278

    申请日:2006-06-22

    IPC分类号: H01J49/00

    CPC分类号: H01J49/4225

    摘要: A mass spectrometer is disclosed comprising an ion trap wherein ions which have been temporally separated according to their mass to charge ratio or ion mobility enter the ion trap. Once at least some of the ions have entered the ion trap, a plurality of ion trapping regions are created along the length of the ion trap in order to fractionate the ions. Alternatively, the ions may be received within one or more axial trapping regions which are translated along the ion trap with a velocity which is progressively reduced to zero.

    摘要翻译: 公开了一种质谱仪,其包括离子阱,其中根据其质荷比或离子迁移率暂时分离的离子进入离子阱。 一旦至少一些离子已经进入离子阱,沿着离子阱的长度产生多个离子捕获区域,以分离离子。 或者,离子可以被接收在一个或多个沿着离子阱平移的轴向捕获区域中,其速度逐渐减小到零。

    Mass spectrometer
    5.
    发明申请
    Mass spectrometer 有权
    质谱仪

    公开(公告)号:US20050023453A1

    公开(公告)日:2005-02-03

    申请号:US10633702

    申请日:2003-08-05

    IPC分类号: H01J49/00 H01J49/42

    CPC分类号: H01J49/4225

    摘要: A mass spectrometer is disclosed comprising an ion trap wherein ions which have been temporally separated according to their mass to charge ratio or ion mobility enter the ion trap. Once at least some of the ions have entered the ion trap, a plurality of ion trapping regions are created along the length of the ion trap in order to fractionate the ions. Alternatively, the ions may be received within one or more axial trapping regions which are translated along the ion trap with a velocity which is progressively reduced to zero.

    摘要翻译: 公开了一种质谱仪,其包括离子阱,其中根据其质荷比或离子迁移率暂时分离的离子进入离子阱。 一旦至少一些离子已经进入离子阱,沿着离子阱的长度产生多个离子捕获区域,以分离离子。 或者,离子可以被接收在一个或多个沿着离子阱平移的轴向捕获区域中,其速度逐渐减小到零。

    Method and apparatus for non-destructive detection of defects in composite laminate structures
    6.
    发明申请
    Method and apparatus for non-destructive detection of defects in composite laminate structures 审中-公开
    用于复合层压结构中缺陷的非破坏性检测的方法和装置

    公开(公告)号:US20100171518A1

    公开(公告)日:2010-07-08

    申请号:US12654313

    申请日:2009-12-16

    IPC分类号: G01R27/08

    CPC分类号: G01N25/18

    摘要: The present invention provides a probe apparatus and method as described below for use as a non-destructive testing (NDT) device to detect and locate structural flaws in a composite laminate. In preferred embodiments, the method includes measuring effective thermal conductivity (Ke) of the laminate using one contact surface, non-invasively. The device is preferably portable and battery-operated. The thermal conductivity method on which the device is based is much simpler to use than the known devices for NDT and allows the utilization of a direct correlation between thermal conductivity and mechanical strength in the case of polymer composites. The device may also be used for process control in manufacturing and monitoring materials in service.

    摘要翻译: 本发明提供如下所述的探针装置和方法,用于无损检测(NDT)装置,用于检测和定位复合层压板中的结构缺陷。 在优选实施例中,该方法包括使用一个接触表面非侵入地测量层压体的有效热导率(Ke)。 该装置优选是便携式和电池供电的。 器件所基于的导热方法比已知的NDT器件要简单得多,并且在聚合物复合材料的情况下允许利用热导率和机械强度之间的直接相关性。 该设备还可用于制造和监控服务中的材料的过程控制。

    Mass spectrometer
    7.
    发明申请
    Mass spectrometer 审中-公开
    质谱仪

    公开(公告)号:US20060138320A1

    公开(公告)日:2006-06-29

    申请号:US11286262

    申请日:2005-11-23

    申请人: Robert Bateman

    发明人: Robert Bateman

    IPC分类号: H01J49/00 B01D59/44

    摘要: A method of mass spectrometry is disclosed wherein a collision, fragmentation or reaction device is repeatedly switched between a high fragmentation or reaction mode and a low fragmentation or reaction mode. Parent ions from a first sample are passed through the device and parent ion mass spectra and fragmentation ion mass spectra are obtained. Parent ions from a second sample are then passed through the device and a second set of parent ion mass spectra and fragmentation ion mass spectra are obtained. The mass spectra are then compared and if either certain parent ions or certain fragmentation ions in the two samples are expressed differently then further analysis is performed to seek to identify the ions which are expressed differently in the two different samples.

    摘要翻译: 公开了一种质谱法,其中碰撞,碎裂或反应装置在高碎裂或反应模式与低碎裂或反应模式之间重复切换。 来自第一个样品的亲本离子通过器件,并获得亲本离子质谱和碎片离子质谱。 然后将来自第二个样品的母离子通过该装置,并获得第二组母离子质谱和碎裂离子质谱。 然后比较质谱,并且如果两个样品中的某些亲本离子或某些断裂离子不同地表达,则进行进一步分析以寻找在两个不同样品中不同表达的离子。

    Coach seat locking mechanism
    8.
    发明授权
    Coach seat locking mechanism 失效
    教练座椅锁定机构

    公开(公告)号:US4925227A

    公开(公告)日:1990-05-15

    申请号:US402795

    申请日:1989-09-05

    申请人: Robert Bateman

    发明人: Robert Bateman

    IPC分类号: B61D33/00

    CPC分类号: B61D33/00

    摘要: A coach seat locking mechanism is disclosed which is compatible for use with existing revolving type coach seats. A metallic body having a vertical bore is affixed to one end of the seat lower frame and a locking rod is vertically reciprocal within the bore between an upper, locking position and a lower, unlocked position. A pedal arm having a cam is pivotally affixed to the body and is designed for foot operation form an upper, locking position to a lower, unlocked position. Upon depressing the pedal arm, the locking rod is lowered to its unlocked position and simultaneously, the pedal cam contacts a body affixed extraction arm to transversely move the seat upper frame away from the coach sidewall. A detent is pivotally secured to the body to maintain the pedal arm in its unlocked position. Upon rotating the seat upper frame through one hundred and eighty degrees, the parts are automatically returned to their initial, unlocked positions to thereby prevent seat upper frame rotation even under the most severe or stressed conditions.

    摘要翻译: 公开了一种与现有的旋转式长途客车座椅兼容的长途客车座椅锁定机构。 具有垂直孔的金属体固定在座椅下部框架的一端,并且锁定杆在上部锁定位置和下部解锁位置之间在孔内垂直往复。 具有凸轮的踏板臂枢转地固定到主体上,并且被设计成用于脚操作,从而形成上部锁定位置到较低的解锁位置。 在按下踏板臂时,锁定杆下降到其解锁位置,同时踏板凸轮接触主体固定的提取臂,以将座椅上部框架横向移动离开教练侧壁。 棘爪被枢转地固定到身体以将踏板臂保持在其解锁位置。 当座椅上框架旋转了一百八十度时,这些部件自动地返回到其初始的解锁位置,从而即使在最严重或受压条件下也能防止座椅上框架旋转。

    Mass spectrometer
    9.
    发明申请
    Mass spectrometer 有权
    质谱仪

    公开(公告)号:US20070114439A1

    公开(公告)日:2007-05-24

    申请号:US10893427

    申请日:2004-07-16

    IPC分类号: H01J27/00

    CPC分类号: H01J49/168 H01J49/145

    摘要: An Atmospheric Pressure Chemical Ionisation (“APCI”) ion source is disclosed comprising a housing 14 having a corona discharge chamber 1, a reaction chamber 2 and a passage 6 connecting the corona discharge chamber 1 to the reaction chamber 2. Reagent ions are formed in the corona discharge chamber 1 and pass to the reaction chamber 2 via the passage 6. Analyte is sprayed into a heated tube 3. Low to moderately polar analyte molecules pass from the heated tube 3 into the reaction chamber 2 whereupon the analyte molecules are ionised by interacting with reagent ions. In contrast, highly polar analytes are ionised by thermal ionisation processes within the heated tube 3 and hence highly polar analyte ions pass into the reaction chamber 2. Analyte ions entering the reaction chamber 2 are substantially shielded from the effects of an electric field generated in the corona discharge chamber 1 as part of the process of generating reagent ions. The APCI ion source according to the preferred embodiment is able to optimally ionise a sample containing both low to moderately polar analytes and also highly polar analytes.

    摘要翻译: 公开了一种大气压化学电离(“APCI”)离子源,其包括具有电晕放电室1,反应室2和将电晕放电室1连接到反应室2的通道6的壳体14。 在电晕放电室1中形成试剂离子,并通过通道6进入反应室2。 将分析物喷入加热管3中。 低至中等极性的分析物分子从加热管3进入反应室2,于是分析物分子通过与试剂离子相互作用而离子化。 相比之下,高极性分析物通过加热管3内的热离子化过程进行电离,因此高极性分析物离子进入反应室2。 作为产生试剂离子的过程的一部分,进入反应室2的分析物离子基本上不受电晕放电室1中产生的电场的影响的影响。 根据优选实施方案的APCI离子源能够最佳地离子化含有低至中等极性的分析物和高极性分析物的样品。

    Mass spectrometer
    10.
    发明申请
    Mass spectrometer 有权
    质谱仪

    公开(公告)号:US20070034796A1

    公开(公告)日:2007-02-15

    申请号:US10535053

    申请日:2003-10-28

    IPC分类号: H01J49/30 H01J49/32

    CPC分类号: H01J49/30

    摘要: A magnetic sector mass spectrometer is disclosed comprising an ion detector (11) wherein a reflecting electrode (13) is used to divide an ion beam in the direction of mass dispersion into two separate ion beams. The two ion beams are directed onto two detectors which preferably comprise two or more conversion dynodes (15a, 15b) and two or more corresponding microchannel plate detectors (14a, 14b) to detect electrons produced by the conversion dynodes (15a, 15b). If the signal from the two detectors differs substantially then the ion beam can be determined to include interference ions. Conversely, if the signal from the two detectors is substantially the same then the ion beam can be determined to be substantially free from interference ions.

    摘要翻译: 公开了一种磁性扇形质谱仪,其包括离子检测器(11),其中使用反射电极(13)将质谱分散的离子束分成两个分离的离子束。 两个离子束被引导到两个检测器上,优选地包括两个或更多个转换倍增极(15a,15b)和两个或更多个相应的微通道板检测器(14a,14b),以检测由转换倍增电极(15a)产生的电子 ,15 b)。 如果来自两个检测器的信号基本相差,则可以确定离子束包括干涉离子。 相反,如果来自两个检测器的信号基本相同,则可以确定离子束基本上不含干扰离子。