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公开(公告)号:US06346608B1
公开(公告)日:2002-02-12
申请号:US09621855
申请日:2000-07-24
申请人: Martin Karl Russel Burnham , Andrew Fosberry , John Hodgson , Deborah Jaworski , Elizabeth Lawlor , Martin Rosenberg , Lisa Kathleen Shilling , Min Wang , Judith Ward
发明人: Martin Karl Russel Burnham , Andrew Fosberry , John Hodgson , Deborah Jaworski , Elizabeth Lawlor , Martin Rosenberg , Lisa Kathleen Shilling , Min Wang , Judith Ward
IPC分类号: C07K100
CPC分类号: C12N9/14 , A61K38/00 , A61K48/00 , Y10S530/82 , Y10S530/825
摘要: The invention provides mecB polypeptides and polynucleotides encoding mecB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing mecB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了mecB多肽和编码mecB多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用mecB多肽筛选抗菌化合物的方法。
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公开(公告)号:US6124119A
公开(公告)日:2000-09-26
申请号:US40843
申请日:1998-03-18
申请人: Deborah Jaworski , Elizabeth Lawlor , Martin Rosenberg , Lisa Kathleen Shilling , Min Wang , Judith Ward , Martin Karl Russel Burnham , Andrew Fosberry , John Hodgson
发明人: Deborah Jaworski , Elizabeth Lawlor , Martin Rosenberg , Lisa Kathleen Shilling , Min Wang , Judith Ward , Martin Karl Russel Burnham , Andrew Fosberry , John Hodgson
IPC分类号: G01N33/50 , A61K31/00 , A61K35/76 , A61K38/00 , A61K38/45 , A61K38/46 , A61K39/085 , A61K39/395 , A61K45/00 , A61K48/00 , A61P1/00 , A61P1/04 , A61P9/00 , A61P11/00 , A61P13/00 , A61P13/02 , A61P13/12 , A61P17/00 , A61P19/00 , A61P19/02 , A61P27/00 , A61P27/02 , A61P31/00 , A61P31/04 , C07K14/195 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/14 , C12N9/16 , C12N15/00 , C12N15/09 , C12N15/55 , C12Q1/42 , C12Q1/68 , C12R1/445 , G01N33/15 , G01N33/53 , G01N33/566 , G01N33/569 , G01N33/68 , C12P21/06 , C07H21/04 , C12N1/20 , C12N5/00
CPC分类号: C12N9/14 , A61K38/00 , A61K48/00 , Y10S530/82 , Y10S530/825
摘要: The invention provides mecB polypeptides and polynucleotides encoding mecB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing mecB polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了mecB多肽和编码mecB多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用mecB多肽筛选抗菌化合物的方法。
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公开(公告)号:US06524813B1
公开(公告)日:2003-02-25
申请号:US09040796
申请日:1998-03-18
申请人: Martin Karl Russel Burnham , Andrew Fosberry , John Hodgson , Deborah Jaworski , Elizabeth Lawlor , Martin Rosenberg , Lisa Kathleen Shilling , Min Wang , Judith Ward
发明人: Martin Karl Russel Burnham , Andrew Fosberry , John Hodgson , Deborah Jaworski , Elizabeth Lawlor , Martin Rosenberg , Lisa Kathleen Shilling , Min Wang , Judith Ward
IPC分类号: C12N1531
CPC分类号: C07K14/31 , A61K38/00 , A61K39/00 , A61K2039/51
摘要: The invention provides spo0J1 polypeptides and polynucleotides encoding spo0J1 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing spo0J1 polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了spo0J1多肽和编码spo0J1多肽的多核苷酸以及通过重组技术产生此类多肽的方法。 还提供了利用spo0J1多肽筛选抗菌化合物的方法。
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公开(公告)号:US20060083752A1
公开(公告)日:2006-04-20
申请号:US11166905
申请日:2005-06-23
申请人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
发明人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
IPC分类号: A61K39/02 , C07H21/04 , C12N15/74 , C07K14/195 , C12N1/21
CPC分类号: C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
摘要: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
摘要翻译: 本发明涉及新鉴定的葡萄球菌多核苷酸,由这种多核苷酸编码的多肽,这种多核苷酸和多肽的用途,以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号:US20080076709A1
公开(公告)日:2008-03-27
申请号:US11698250
申请日:2007-01-25
申请人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
发明人: Michael Black , Martin Burnham , Jason Fedon , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Leslie Palmer , Julie Pratt , Raymond Reichard , Martin Rosenberg , Christopher Traini , Judith Ward , Richard Warren
CPC分类号: C12N9/0036 , A61K38/00 , A61K39/00 , C07K14/31 , C07K16/1275 , C07K2319/00 , C12N9/78 , C12N15/52 , C12Q1/689 , C12Q2600/158 , C12Y105/0103 , C12Y305/04025
摘要: This invention relates to newly identified Staphylococcal polynucleotides, polypeptides encoded by such polynucleotides, the uses of such polynucleotides and polypeptides, as well as the production of such polynucleotides and polypeptides and recombinant host cells transformed with the polynucleotides. This invention also relates to inhibiting the biosynthesis or action of such polynucleotides or polypeptides and to the use of such inhibitors in therapy.
摘要翻译: 本发明涉及新鉴定的葡萄球菌多核苷酸,由这种多核苷酸编码的多肽,这种多核苷酸和多肽的用途,以及这些多核苷酸和多肽的产生以及用多核苷酸转化的重组宿主细胞。 本发明还涉及抑制这些多核苷酸或多肽的生物合成或作用以及这种抑制剂在治疗中的用途。
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公开(公告)号:US20060239991A1
公开(公告)日:2006-10-26
申请号:US11338098
申请日:2006-01-24
申请人: John Hodgson , Elizabeth Lawlor
发明人: John Hodgson , Elizabeth Lawlor
CPC分类号: C12N9/93 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/51 , G01N33/573 , G01N2333/9015 , G01N2500/04
摘要: The invention provides tRNA synthetase polypeptides and DNA (RNA) encoding tRNA synthetase polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tRNA synthetase polypeptide for the protection against infection, particularly bacterial infections.
摘要翻译: 本发明提供了tRNA合成酶多肽和编码tRNA合成酶多肽的DNA(RNA),以及通过重组技术产生此类多肽的方法。 还提供了利用tRNA合成酶多肽来保护免受感染,特别是细菌感染的方法。
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公开(公告)号:US06364239B1
公开(公告)日:2002-04-02
申请号:US09458256
申请日:1999-12-09
申请人: Frederick Jallot , Paul Slack , John Hodgson
发明人: Frederick Jallot , Paul Slack , John Hodgson
IPC分类号: B60R2240
CPC分类号: B60R22/40 , B60R2022/401
摘要: A seat belt retractor has a frame, a spool rotatably mounted to the frame, a spool locking device for preventing rotation of the spool. An actuator actuates the spool locking device and has a support carrying an inertia mass and a pawl. The inertia mass is designed to move from an initial position to an actuating position to bring the pawl into engagement with a ratchet on the spool. Engagement of the pawl with the ratchet actuates the spool locking device. The support is arranged to pivot so as to adjust the distance between the pawl and the ratchet. In that way the position of the pawl can be adjusted to provide an optimum gap between the pawl tip and the ratchet on the spool.
摘要翻译: 安全带卷收器具有框架,可旋转地安装在框架上的卷轴,用于防止卷轴旋转的卷轴锁定装置。 致动器致动卷轴锁定装置并具有承载惯性质量块和棘爪的支撑件。 惯性质量被设计成从初始位置移动到致动位置,以使棘爪与阀芯上的棘轮接合。 棘爪与棘轮的接合致动阀芯锁定装置。 支撑件布置成枢转以便调节棘爪和棘轮之间的距离。 以这种方式,可以调节棘爪的位置,以在棘爪头和滑阀上的棘轮之间提供最佳的间隙。
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公开(公告)号:US4097342A
公开(公告)日:1978-06-27
申请号:US750352
申请日:1976-12-14
CPC分类号: C25D5/44 , C25D7/0614
摘要: A process for the production of electroplated aluminium stock, such as strip or wire, comprises passing the stock continuously through a bath having a high dissolving power for aluminium oxide, such as strong aqueous sulphuric acid and phosphoric acid and subsequently through an electroplating bath, the first bath having a cathode electrode and the electroplating bath having an anode electrode so that the stock is anodic in the first bath. The stock may pass through one or more intermediate non-electrolytic treatment stages, such as immersion tinning or zincating. It may also pass through one or more electrolytic pretreatment stages during its passage between the first bath and the electroplating bath. In such pretreatment stages, such as the application of a bronze strike, there may be an anode electrode at the same potential as the anode in the electroplating bath.
摘要翻译: 用于生产电镀铝原料(例如带材或线材)的方法包括将原料连续地通过具有高溶解力的浴,其中氧化铝例如强硫酸水溶液和磷酸,然后通过电镀浴, 具有阴极电极的第一浴和具有阳极电极的电镀浴使得第一浴中的原料是阳极的。 原料可以通过一个或多个中间非电解处理阶段,例如浸渍镀锡或镀锌。 它也可以在其在第一浴和电镀浴之间通过期间通过一个或多个电解预处理阶段。 在这样的预处理阶段,例如施加青铜冲击,可能存在与电镀浴中的阳极相同的电位的阳极电极。
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公开(公告)号:US20070140400A1
公开(公告)日:2007-06-21
申请号:US11583546
申请日:2006-10-19
申请人: John Hodgson
发明人: John Hodgson
IPC分类号: H05H1/22
摘要: In accordance with the present invention, this invention creates the process of cold fusion with the creation of electromagnetic scalar waves and the deuterium loading of cathode in the invention. This process of combining the deuterium loading and current flow of the cathode with the electromagnetic scalar waves are used to allow temporary changes of the columbic barrier and the van der walls forces to lower levels that will allow fusion of the deuterium atoms in the helium atoms and the release of energy that is involved. Once all these conditions are met cold fusion will occur.
摘要翻译: 根据本发明,本发明在本发明中产生了产生电磁标量波和阴极的氘负载的冷熔融过程。 将阴极的氘负载和电流流动与电磁标量波组合的过程被用于允许临时阻挡层和范德华力的暂时变化,以降低能够使氦原子中氘原子熔化的水平, 释放所涉及的能量。 一旦满足这些条件,就会发生冷融合。
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公开(公告)号:US20070009546A1
公开(公告)日:2007-01-11
申请号:US11403784
申请日:2006-04-13
申请人: Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
发明人: Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
IPC分类号: A61K39/02 , C07H21/04 , C12P21/06 , C12N1/21 , C07K14/315
CPC分类号: C12N9/1077 , A61K38/00 , A61K39/00 , C07K14/3156 , C07K2319/00 , C12N9/1205 , C12N9/78 , C12N9/80 , C12Y207/01002
摘要: The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.
摘要翻译: 本发明提供了编码这种多肽的新型多肽和多核苷酸以及通过重组技术产生这种多肽的方法。 还提供了利用这些多肽筛选抗菌化合物的方法。
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