利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

50 条记录 (耗时 0.035 秒)

    Process for the preparation of glycidyl ethers
    1.
    发明授权
    Process for the preparation of glycidyl ethers 失效
    制备甘油三酯的方法

    公开(公告)号：US5162547A

    公开(公告)日：1992-11-10

    申请号：US804309

    申请日：1991-12-09

    申请人： Martin Roth ,  Heinz Wolleb ,  Marc-Andre Truffer

    发明人： Martin Roth ,  Heinz Wolleb ,  Marc-Andre Truffer

    IPC分类号： B01J27/135 ,  C07B61/00 ,  C07D301/28 ,  C07D303/22 ,  C07D303/24

    CPC分类号： C07D303/22 ,  C07D303/24

    摘要： An improved process for the preparation of glycidyl ethers of formula I ##STR1## wherein Q is an aliphatic, cycloaliphatic or araliphatic radical of a valency m, R is --H or --CH.sub.3, and m is an integer from 1 to 10,by reacting an alcohol of formula Q--(OH).sub.m with m mol of an epihalohydrin of formula II ##STR2## in the presence of a catalyst to the corresponding halohydrin ether, and dehydrohalogenating said halohydrin ether with an alkali metal hydroxide to give a compound of formula I, wherein Q, m and R are as defined above and Hal is halogen,which process comprises using as catalysta) tin difluoride orb) a divalent tin halide in conjunction with a co-catalyst.

    摘要翻译： 制备式I的缩水甘油醚的改进方法（I）其中Q是化合价m的脂族，脂环族或芳脂族基团，R是-H或-CH 3，m是1至10的整数 通过使式Q-（OH）m的醇与m摩尔式II的表卤代醇在催化剂存在下反应至相应的卤代醇醚，并用碱金属氢氧化物将所述卤代醇醚脱卤化氢 得到式I化合物，其中Q，m和R如上所定义，Hal为卤素，该方法包括使用二氯化锡或b）与助催化剂结合的二价卤化锡。

    Merocyanine derivatives
    4.
    发明授权
    Merocyanine derivatives 有权

    公开(公告)号：US07772242B2

    公开(公告)日：2010-08-10

    申请号：US11630489

    申请日：2005-06-20

    申请人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    发明人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    IPC分类号： A61K31/519 ,  A61K31/445 ,  A61K31/16 ,  A61K31/165

    CPC分类号： A61K8/498 ,  A61K8/4913 ,  A61K8/494 ,  A61Q17/04

    摘要： Disclosed is the use of the compounds of formula  wherein Q is —OH; —OR7; —NH2; —NHR7; —NR7R8; or —N═R9; T is —COR5; —CN; or —SO2—(C6-C12)aryl; R1 is hydrogen; —OR7, —SR7; —NHR7; —NR7R8; C1-C22alkyl; C2-C12Alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R2 and R3 independently from each other are C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl, C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C3-C12cycloheteroalkyl; C2-C11heteroaralkyl, C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONH2; CONHR7; CONR7R8; SO2(C6-C12)aryl, C2-C12alk-1 -enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl, C3-C5heterocycloalkyl, C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl or C1-C9heteroaryl; R6, R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; o-C6-C10aryl; or C1-C9heteroaryl; R9 is a (C1-C6)alkylidene radical; or R1 and R2, R1 and Q, R1 and R4, R1 and R6, R2 and R3, R3 and Q, R6 and Q, T and Q, each independently, are linked together, so that 1, 2, 3 or 4 carbocyclic or N, O and/or S-heterocyclic rings are formed, wherein each of them, independently from each other, may be condensed with an aromatic or heteroaromatic ring, and/or more N-, O- and/or S-heterocycic rings, and each N atom in a N-heterocyclic ring may be substituted by C1-C22alkyl; and n is a number from 1 to 4; for protecting of human hair and skin against the damaging effect of UV radiation.

    MEROCYANINE DERIVATIVES
    9.
    发明申请
    MEROCYANINE DERIVATIVES 有权
    月桂酰胺衍生物

    公开(公告)号：US20100209466A1

    公开(公告)日：2010-08-19

    申请号：US12715839

    申请日：2010-03-02

    申请人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    发明人： Barbara Wagner ,  Frank Bienewald ,  Heinz Wolleb ,  Olof Wallquist ,  Bernd Herzog ,  Thomas Ehlis ,  Jürg Haase

    IPC分类号： A61K8/41 ,  A61Q17/04 ,  A61K8/49 ,  A61K8/42 ,  A61K8/46 ,  A61K8/58 ,  A61K8/898 ,  A61K8/02

    CPC分类号： A61K8/498 ,  A61K8/4913 ,  A61K8/494 ,  A61Q17/04

    摘要： Disclosed is the use of merocyanine derivatives of formula Q is hydrogen; C1-C22alkyl; —OH; —OR7; —NR7R8; or —N═R9; R1 is hydrogen; C1-C22alkyl; —OR7, —SR7; —NR7R8; C1-C22alkyl; C2-C12 alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12heteroalkyl, C2-C11heteroaralkyl; C6-C10aryl; or C1-C9heteroaryl; R4 is cyano; COR7, COOR7; CONR7R8; SO2(C6-C12)aryl; C2-C12alk-1-enyl; C3-C12cycloalk-1-enyl; C2-C12alk-1-inyl; C2-C12heteroalkyl; C3-C5heterocycloalkyl; C6-C10aryl; or C1-C9heteroaryl; R5 is —COR7; —COOR7; —OR7; —SR7, —NHR7, —NR7R8; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; C7-C12aralkyl; C1-C12alkylphenyl; C1-C12alkoxy-C6-C10aryl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C3-C12cycloheteroalkyl; C6-C10aryl; C1-C12alkoxy-C6-C10aryl; or C1-C9heteroaryl; R6 is hydrogen; C1-C22alkyl; C1-C22alkoxy; or COR7; R7 and R8 independently from each other are hydrogen; C1-C22alkyl; C2-C12alkenyl; C2-C12alkinyl; C3-C12cycloalkyl; C3-C12cycloalkenyl; —(CH2)tCOOH; C7-C12aralkyl; C1-C12heteroalkyl; C2-C11heteroaralkyl; C6-C10aryl; C1-C9heteroaryl; Si—R10R11R12; Si(OR10)(OR11)(OR12); SiR10(OR11)(OR12); SiR10R11(OR12); —(CH2)u—O—(CH2)v—SiR10R11R12; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R9 is a (C1-C6)alkylidene radical; R10, R11, R12 independently form each other are C1-C22alkyl; X is a linker; for protecting of human hair and skin against the damaging effect of UV radiation.

    摘要翻译： 公开了使用式Q的部花青衍生物是氢; C 1 -C 22烷基; -哦; -OR7; -NR7R8; 或-N = R9; R1是氢; C 1 -C 22烷基; -OR7，-SR7; -NR7R8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12杂烷基，C 2 -C 11杂芳烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R4是氰基; COR7，COOR7; CONR7R8; SO2（C6-C12）芳基; C2-C12烷-1-烯基; C 3 -C 12环烯-1-烯基; C2-C12alk-1-inyl; C 2 -C 12杂烷基; C3-C5杂环烷基; C6-C10芳基; 或C 1 -C 9杂芳基; R5是-COR7; -COOR7; -OR7; -SR 7，-NHR 7，-NR 7 R 8; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; C7-C12芳烷基; C 1 -C 12烷基苯基; C 1 -C 12烷氧基-C 6 -C 10芳基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C 3 -C 12环杂烷基; C6-C10芳基; C 1 -C 12烷氧基-C 6 -C 10芳基; 或C 1 -C 9杂芳基; R6是氢; C 1 -C 22烷基; C1-C22烷氧基; 或COR7; R 7和R 8彼此独立地是氢; C 1 -C 22烷基; C 2 -C 12烯基; C 2 -C 12炔基; C 3 -C 12环烷基; C3-C12环烯基; - （CH 2）t COOH; C7-C12芳烷基; C 1 -C 12杂烷基; C 2 -C 11杂芳烷基; C6-C10芳基; C1-C9杂芳基; Si-R10R11R12; Si（OR10）（OR11）（OR12）; SiR10（OR11）（OR12）; SiR10R11（OR12）; - （CH 2）u -O-（CH 2）v -SiR 10 R 11 R 12; 或X-Sil基团; t，u和v彼此独立地为1至5的数; R9是（C1-C6）亚烷基; R 10，R 11，R 12彼此独立地为C 1 -C 22烷基; X是一个连接子; 用于保护人的头发和皮肤免受紫外线辐射的破坏作用。