Compositions and methods for the treatment of wounds and the reduction of scar formation
    1.
    发明申请
    Compositions and methods for the treatment of wounds and the reduction of scar formation 失效
    用于治疗创伤和减少瘢痕形成的组合物和方法

    公开(公告)号:US20070059377A1

    公开(公告)日:2007-03-15

    申请号:US11476543

    申请日:2006-06-28

    摘要: The present invention relates to methods and compositions for inhibiting scar formation on wound region. In certain embodiments, the methods include administering an alkalinization agent in combination with hyaluronic acid to a wound site to reduce the formation of scars at the wound site. Suitable alkalization agents include sodium bicarbonate, sodium hydroxide and potassium hydroxide.

    摘要翻译: 本发明涉及用于抑制伤口区域上的瘢痕形成的方法和组合物。 在某些实施方案中,所述方法包括向伤口部位施用与透明质酸组合的碱化剂以减少伤口位置处的瘢痕形成。 合适的碱化剂包括碳酸氢钠,氢氧化钠和氢氧化钾。

    Composition for preventing the formation of new scar comprising bmp-7
    10.
    发明申请
    Composition for preventing the formation of new scar comprising bmp-7 审中-公开
    用于防止形成包含bmp-7的新疤痕的组合物

    公开(公告)号:US20060122109A1

    公开(公告)日:2006-06-08

    申请号:US10534590

    申请日:2003-07-04

    IPC分类号: A61K38/17

    CPC分类号: A61K38/1875

    摘要: Composition for preventing the formation of new scar, e.g. myofibroblast, having BMP-7 polypeptide is disclosed. The composition for preventing the formation of scar includes an effective amount of BMP-7 (Bone Morphogenic Protein-7) polypeptide of sequence 1. The effective amount is 50 ng/ml-50 μg/ml or 0.1 ng-1 μg/kg by weight and the scar is a corneal scar.

    摘要翻译: 用于防止形成新瘢痕的组合物,例如 公开了具有BMP-7多肽的肌成纤维细胞。 用于防止形成瘢痕的组合物包括有效量的序列1的BMP-7(骨形态发生蛋白-7)多肽。有效量为50ng / ml-50ug / ml或0.1ng-1μg/ kg, 重量和疤痕是角膜瘢痕。