摘要:
The present invention provides an immunoassay for phthalic acid esters, which comprises measuring the phthalic acid esters contained in a sample using an antibody produced with a conjugate of a carrier protein and a phthalic acid ester derivative represented by the formula wherein R1 and R2 may be the same or different and are hydrogen, alkyl, cycloalkyl or phenylalkyl, with the proviso that both of R1 and R2 are not hydrogen; m is an integer from 1 to 5; and Y is amino or carboxyl.
摘要:
Provided is an irinotecan formulation capable of supporting irinotecan and/or a salt thereof in a closed vesicle carrier at a high concentration and existing in blood for a long period of time by dramatically improved retentivity in blood compared to a conventionally known irinotecan liposome formulation. That is, an irinotecan formulation including a closed vesicle formed by a lipid membrane, in which irinotecan and/or a salt thereof is encapsulated at a concentration of at least 0.07 mol/mol (drug mol/membrane total lipid mol). There is an ion gradient between an inner aqueous phase and an outer aqueous phase in the irinotecan formulation. The closed vesicle is preferably liposome, in which only the outer surface of the liposome is preferably modified with a surface-modifying agent containing a hydrophilic polymer.
摘要:
A rim (10) is produced by a production process including a step (A) of bending a workpiece (11) to bring end faces of the workpiece into contact with each other, a step (B) of forming a circular cylinder body (12) by joining the end faces brought to be in contact with each other, a step (C) of inspecting a joint portion (13) of the circular cylinder body (12), a step (D) of forming a drop portion (16), subsiding toward the inner peripheral wall (15) side, in an outer peripheral wall (14) of the circular cylinder body (12), a by bending both end portions of the circular cylinder body (12), a step (F) of forming hump portions (20) by pressing the circular cylinder body (12) from the inner peripheral wall (15) side to raise the outer peripheral wall (14), and a step (G) for forming a valve hole (22) and water drain holes (24) in the drop portion (16) and the curl portions (18). The rim (10) and a disk (102) that is separately produced are welded to form a wheel (122).
摘要:
Provided is an irinotecan formulation capable of supporting irinotecan and/or a salt thereof in a closed vesicle carrier at a high concentration and existing in blood for a long period of time by dramatically improved retentivity in blood compared to a conventionally known irinotecan liposome formulation. That is, an irinotecan formulation including a closed vesicle formed by a lipid membrane, in which irinotecan and/or a salt thereof is encapsulated at a concentration of at least 0.07 mol/mol (drug mol/membrane total lipid mol). There is an ion gradient between an inner aqueous phase and an outer aqueous phase in the irinotecan formulation. The closed vesicle is preferably liposome, in which only the outer surface of the liposome is preferably modified with a surface-modifying agent containing a hydrophilic polymer.
摘要:
A method for manufacturing a drink made from beans as a raw material and a solid fermented food. It is characterized in that it comprises the steps of: preparing a stabilized suspension by homogenization-treating an aqueous slurry of whole grain-mash of beans once or a plurality of times using a homogenizer; denaturing protein by adding a coagulant and/or a pH adjustor to the stabilized suspension; and performing the dispersing treatment for making the relevant protein denaturation raw material dispersed by a physical dispersing means. In a solid fermented food, it comprises a step of fermenting for fermenting/solidifying by adding a lactic bacterium starter following the step of performing a homogenization treatment, and manufactures it via the step of maturating it if it is necessary.
摘要:
The present invention provides a highly sensitive immunoassay system for estrogens, which utilizes as a labeled compound a biotinylated estradiol derivative of the formula (1) wherein one of R1 and R2 is hydrogen and the other is a group represented by wherein R3s are the same or different and represent an arginine residue or a lysine residue, x is 0 or 1, y is an integer from 1 to 5, and z is an integer from 1 to 3.
摘要:
The present invention relates to a Lactobacillus pentosus strain FERM BP-10958, a method for producing fermented food or drink with a fermentation process using the lactic acid bacteria, and fermented food or drink produced by fermentations using the lactic acid bacteria.
摘要:
A method of forming a hollow curled portion on a hollow body, the curled portion being oriented from one end to the other end of the hollow body. The method includes a bending step of curving an end of the hollow body toward another end of the hollow body, thereby forming a curled portion, an ironing step of ironing the curled portion with a die, and a recurving step of stopping the die from ironing the curled portion and allowing the curled portion to recurve under its own resiliency in a direction opposite to the direction in which the end of the hollow body has been curved. The ironing step and the recurving step are repeated.
摘要:
Electronic parts, such as an inductor, of improved connectivity between magnetic and conductive materials are made by sintering magnetic material under a condition in which no accumulation is developed, by forming a hollow-core of a shape different from an external shape of said conductive material through said magnetic material to be molded by an extrusion-molding means while inserting said magnetic material into said hollow-core, or by providing an erasable means to be removed by a heat treatment in said conductive material and conducting extrusion molding so as to embed said conductive material into said magnetic material, said erasable means being removed during a sintering treatment to form a space between said conductive material and said magnetic material, and a method for making same.