公开(公告)号：US06710150B2

公开(公告)日：2004-03-23

申请号：US09995817

申请日：2001-11-29

申请人： Masatoshi Yoshida ,  Shigeru Tanimori ,  Yasutaka Nakatani ,  Yohei Murakami ,  Hideaki Nagano

发明人： Masatoshi Yoshida ,  Shigeru Tanimori ,  Yasutaka Nakatani ,  Yohei Murakami ,  Hideaki Nagano

IPC分类号： C08F11802

CPC分类号： G03F7/0392 ,  C08F8/12 ,  C08F212/14

摘要： The present invention provides a protolytically leaving group-containing copolymer having improved characteristics such as increased solubility in alkaline aqueous solution in the presence of a proton, thus finding application with advantage in various uses, and a process for producing the copolymer. A protolytically leaving group-containing copolymer represented by the following general formula (1): in the formula, R1, R2 and R3 are the same or different and each represents a protolytically leaving group and a, b and c represent the amounts of existence (mole %) of repeating units (A), (B) and (C), respectively, in the copolymer, which comprises the repeating unit (A) as well as the repeating unit (B) and/or the repeating unit (C) and has a weight average molecular weight of 2000˜30000, said a, b and c satisfying the condition that a is 5 to 30 mole % and (b+c) is 70 to 95 mole %.

摘要翻译： 本发明提供了一种具有改进特性的原位离去基团的共聚物，例如在质子存在下在碱性水溶液中的溶解度增加，从而在各种用途中有利地得到应用，以及制备共聚物的方法。原始离去基团 （1）表示的共聚物：在式中，R 1，R 2和R 3相同或不同，各自表示离子基团，a，b和c表示 包含重复单元（A）的共聚物中的重复单元（A），（B）和（C）的存在量（摩尔％）以及重复单元（B）和/或 重复单元（C），重均分子量为2000〜30000，a，b和c满足a为5〜30摩尔％，（b + c）为70〜95摩尔％的条件。

公开(公告)号：US5912384A

公开(公告)日：1999-06-15

申请号：US998825

申请日：1997-12-29

申请人： Hideaki Nagano

发明人： Hideaki Nagano

IPC分类号： C07C213/10 ,  C07C219/08 ,  C07C231/22 ,  C07C233/38 ,  C07C69/52

CPC分类号： C07C213/10

摘要： Color-stabilized basic monomers are provided. Said basic monomers are obtained by adding, to a basic monomer �e.g. an N,N-dialkylaminoalkyl (meth)acrylate or an N,N-dialkylaminoalkyl (meth)acrylamide!, at least one member selected from the group consisting of amido group-containing compounds, phosphorous acid esters, phosphoric acid esters and phosphines and at least one phenol compound represented by the general formula: ##STR1## wherein R.sup.5, R.sup.6, R.sup.8 and R.sup.9 are each independently a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; and R.sup.7 is a hydrogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxy group having 1 to 4 carbon atoms. The color-stabilized basic monomers are more resistant to coloration when they are handled under such conditions that the oxygen concentration in the gas phase contacting therewith is 0.01 to 10% by volume.

摘要翻译： 提供了颜色稳定的碱性单体。 所述碱性单体是通过向碱性单体[例如， N，N-二烷基氨基烷基（甲基）丙烯酸酯或N，N-二烷基氨基烷基（甲基）丙烯酰胺]，选自酰氨基化合物，亚磷酸酯，磷酸酯和膦中的至少一种， 由通式表示的至少一种酚化合物：其中R5，R6，R8和R9各自独立地为氢原子或具有1至4个碳原子的烷基; 并且R 7是氢原子，具有1至4个碳原子的烷基或具有1至4个碳原子的烷氧基。 当在与其接触的气相中的氧浓度为0.01至10体积％的条件下处理时，颜色稳定的碱性单体更易于着色。

公开(公告)号：US06417392B1

公开(公告)日：2002-07-09

申请号：US09164796

申请日：1998-10-01

申请人： Hideaki Nagano ,  Tadayoshi Kawashima ,  Tetsuya Kajihara ,  Kaoru Iwasaki ,  Sumio Nakashima

发明人： Hideaki Nagano ,  Tadayoshi Kawashima ,  Tetsuya Kajihara ,  Kaoru Iwasaki ,  Sumio Nakashima

IPC分类号： C07C6952

CPC分类号： B01D3/009 ,  C07C213/06 ,  Y02P20/127 ,  C07C219/20

摘要： In the operation of producing an alkylamino(meth)acrylate by the reaction of transesterification of an alkyl(meth)acrylate with an alkylamino alcohol, the alkyl alcohol by-produced during the transesterification is distilled in the form of an azeotropic mixture with the alkyl(meth)acrylate, the resultant distillate is purified with an ion-exchange resin and handled, on the other hand, the reaction solution is distilled to allow separation of the catalyst wherein is provided a method and apparatus for effecting, in the production of the alkylamino(meth)acrylate, the distillation under such a condition as represses the amount of in crease of the Michael adduct below 2%.

摘要翻译： 在通过（甲基）丙烯酸烷基酯与烷基氨基醇的酯交换反应制备烷基氨基（甲基）丙烯酸酯的操作中，在酯交换期间副产生的烷基醇与烷基（ 甲基）丙烯酸酯，所得馏出物用离子交换树脂纯化，另一方面，蒸馏反应溶液以允许分离催化剂，其中提供了在制备烷基氨基中实现的方法和装置 （甲基）丙烯酸酯，在抑制迈克尔加合物的折痕量低于2％的条件下进行蒸馏。

公开(公告)号：US5834576A

公开(公告)日：1998-11-10

申请号：US607605

申请日：1996-02-27

申请人： Hideaki Nagano ,  Koichi Nakagawa ,  Keiji Yurugi ,  Mitsuaki Makino ,  Tsuyoshi Hirata ,  Koichiro Nagare ,  Yuichi Kita

发明人： Hideaki Nagano ,  Koichi Nakagawa ,  Keiji Yurugi ,  Mitsuaki Makino ,  Tsuyoshi Hirata ,  Koichiro Nagare ,  Yuichi Kita

IPC分类号： C04B24/26 ,  C07C59/58 ,  C07C67/31 ,  C07C69/734 ,  C07H15/04 ,  C08F220/64

CPC分类号： C07H15/04 ,  C04B24/2641 ,  C07C59/58 ,  C07C67/31 ,  C07C69/734

摘要： A novel acrylic ester which is represented by general formula (2) ##STR1## wherein R.sub.1 and R.sub.2 independently represent a hydrogen atom or an organic residue, R.sub.3 represents an organic residue, n is a positive number among 1 to 3, and m is a positive number among 1 to 100 and which is applicable to various uses, is obtained by reacting an acrylic ester of general formula (3) ##STR2## wherein R.sub.1 represents a hydrogen atom or an organic residue, and R.sub.3 represents an organic residue, with a cyclic ether compound of general formula (4) ##STR3## wherein R.sub.2 represents a hydrogen atom or an organic residue, and n is a positive number among 1 to 3. Moreover, a novel acrylic acid derivative whose use is even wider is obtained by hydrolyzing the acrylic acid derivative.

摘要翻译： 一种由通式（2）表示的新型丙烯酸酯其中R1和R2独立地表示氢原子或有机残基，R3表示有机残基，n为1〜3的正数， m为1〜100的正数，适用于各种用途，通过使通式（3）的丙烯酸酯与其中R 1表示氢原子或有机残基反应而得到，其中R 3表示 具有通式（4）的环状醚化合物或有机残基的有机残基，n为1〜3的正数。此外，使用更宽的新型丙烯酸衍生物通过水解丙烯酸 酸衍生物。

公开(公告)号：US20100130793A1

公开(公告)日：2010-05-27

申请号：US12594397

申请日：2008-04-04

申请人： Tsutomu Yuasa ,  Yuko Matsuda ,  Naohiko Itayama ,  Hideaki Nagano

发明人： Tsutomu Yuasa ,  Yuko Matsuda ,  Naohiko Itayama ,  Hideaki Nagano

IPC分类号： C07C41/03

CPC分类号： C08F216/125 ,  C08F216/1416 ,  C08F220/06 ,  C08G65/2609

摘要： To provide a production method of a (poly)alkylene glycol chain-containing polymer which can be preferably used in various applications such as an admixture for cement and which can exhibit extremely high dispersibility to a cement composition. The unsaturated (poly)alkylene glycol ether monomer of the present invention is an unsaturated (poly)alkylene glycol ether monomer production method for producing an unsaturated (poly)alkylene glycol ether monomer by addition reaction of an alkylene oxide on an unsaturated alcohol, wherein the production method includes a step of carrying out addition reaction under condition of existence of 0.01 to 25 parts by mass of an unsaturated (poly)alkylene glycol diether monomer to 100 parts by mass of the unsaturated alcohol, and a (poly)alkylene glycol chain-containing polymer production method, wherein a monomer component including an unsaturated (poly)alkylene glycol ether monomer produced by the production method.

摘要翻译： 提供一种（聚）亚烷基二醇链聚合物的制造方法，其可以优选用于各种用途，例如水泥混合物，并且可以显示出对水泥组合物极高的分散性。 本发明的不饱和（聚）亚烷基二醇醚单体是通过烯化氧在不饱和醇上的加成反应制备不饱和（聚）亚烷基二醇醚单体的不饱和（聚）亚烷基二醇醚单体制备方法，其中 制造方法包括在不饱和（聚）亚烷基二醇二醚单体的存在下，在存在0.01〜25质量份的不饱和醇的情况下进行加成反应的工序，和（聚） 其中含有通过该制造方法制造的不饱和（聚）亚烷基二醇醚单体的单体成分。

公开(公告)号：US20090325247A1

公开(公告)日：2009-12-31

申请号：US12096153

申请日：2006-12-01

申请人： Yukiko Kodama ,  Hideaki Nagano ,  Koichi Funato

发明人： Yukiko Kodama ,  Hideaki Nagano ,  Koichi Funato

IPC分类号： C12P7/64

CPC分类号： C12P13/02

摘要： The present invention provides methods for producing human ceramide in a yeast cell.The methods of the present invention comprise: 1) introducing the sphingoid Δ4-desaturase gene (DES1) by transformation of the yeast cell; and 2) abolishing the expression of the yeast sphinganine C4-hydroxylase gene (SUR2) by transformation of the yeast cell.

摘要翻译： 本发明提供了在酵母细胞中生产人神经酰胺的方法。 本发明的方法包括：1）通过转化酵母细胞引入鞘氨醇类脱氢酶脱氢酶基因（DES1）; 和2）通过酵母细胞的转化来消除酵母胞浆素C4-羟化酶基因（SUR2）的表达。

公开(公告)号：US20070037962A1

公开(公告)日：2007-02-15

申请号：US11502355

申请日：2006-08-11

申请人： Ken-ichi Ueda ,  Shigeo Otome ,  Nobuhiro Maeda ,  Hidetaka Nakanishi ,  Hiroko Izumi ,  Hideaki Nagano

发明人： Ken-ichi Ueda ,  Shigeo Otome ,  Nobuhiro Maeda ,  Hidetaka Nakanishi ,  Hiroko Izumi ,  Hideaki Nagano

IPC分类号： C08G63/08

CPC分类号： C08F8/16 ,  C07C67/60 ,  C08F220/18 ,  C08F220/26 ,  C07C69/732

摘要： The lactone ring-containing polymer of the present invention meets the following conditions that: (1) the content of polymer gels of 50 μm or greater in average particle diameter is lower than or equal to 100 pieces/100 g, and the weight average molecular weight of the polymer is 50,000 to 170,000; and/or (2) an increasing rate of viscosity after heated at 280° C. for 30 minutes is 2.0 times or smaller. The lactone ring-containing polymer of the present invention contains very few foreign matters and does not easily cause gelation, in addition to being excellent in transparency and heat resistance as well as having the desired properties such as mechanical strength and forming and processing properties. The forming material obtained by heating and granulating such a polymer are suitable for use in, for example, optical components such as light guide materials, optical lenses, and optical films.

摘要翻译： 本发明的含内酯环的聚合物满足以下条件：（1）平均粒径为50μm以上的聚合物凝胶的含量为100个/ 100g以下，重均分子量 聚合物的重量为50,000至170,000; 和/或（2）在280℃下加热30分钟后的粘度增加率为2.0倍以下。 本发明的含内酯环的聚合物除了具有优异的透明性和耐热性以及具有期望的性能如机械强度和成型加工性能外，还含有极少量的异物并且不容易引起凝胶化。 通过加热造粒这种聚合物而获得的成形材料适用于例如导光材料，光学透镜和光学膜等光学部件。

公开(公告)号：US5574121A

公开(公告)日：1996-11-12

申请号：US262065

申请日：1994-06-17

申请人： Yoshio Irie ,  Nobuyuki Harada ,  Kinya Nagasuna ,  Kohichi Hirota ,  Yoshihiko Masuda ,  Hideaki Nagano ,  Hideyuki Kubo

发明人： Yoshio Irie ,  Nobuyuki Harada ,  Kinya Nagasuna ,  Kohichi Hirota ,  Yoshihiko Masuda ,  Hideaki Nagano ,  Hideyuki Kubo

IPC分类号： A61L15/24 ,  C08F220/04 ,  C08F236/22

CPC分类号： C08F220/04 ,  A61L15/24 ,  Y10S526/93

摘要： A process for preparing an absorbent resin includes the steps of: preparing a first crosslinking agent (A) including at least two polymerizable unsaturated bonds; preparing a second crosslinking agent (B) including at least two polymerizable unsaturated bonds and hydroxyl groups; preparing a crosslinking agent including (A) and (B) with a ratio of (A) to (B) ranging from 95/5 to 50/50; and polymerizing a hydrophilic unsaturated monomer having at least one carboxyl group using the crosslinking agent. The crosslinking agent includes a crosslinking agent which includes a main component at least 90 percent by weight, the main component being an ester having at least two polymerizable unsaturated bonds, wherein the ester is composed of a polyhydroxy alcohol (C) having not more than six carbon atoms and at least three hydroxy groups, and an unsaturated carboxylic acid (D); and a molecular weight ratio of the main component to a standard compound (E) is in the range of from 0.7/1 to less than 1.3/1, (E) being an ester composed of (C) that composes the main component, and (D) that composes the main component, in which all the hydroxy groups in (C) are ester-linked with (D).

摘要翻译： 制备吸收性树脂的方法包括以下步骤：制备包含至少两个可聚合不饱和键的第一交联剂（A）; 制备包含至少两个可聚合不饱和键和羟基的第二交联剂（B）; 制备包含（A）和（B）的交联剂，比例为（A）至（B）为95/5至50/50; 并使用交联剂聚合具有至少一个羧基的亲水性不饱和单体。 交联剂包括交联剂，其包含至少90重量％的主要组分，主要组分是具有至少两个可聚合不饱和键的酯，其中该酯由不超过六个的多羟基醇（C）组成 碳原子和至少三个羟基，和不饱和羧酸（D）; 并且主成分与标准化合物（E）的分子量比在0.7 / 1〜小于1.3 / 1的范围内，（E）是由构成主成分的（C）构成的酯，和 （D）构成其中（C）中的所有羟基与（D）酯连接的主要组分。

公开(公告)号：US08754264B2

公开(公告)日：2014-06-17

申请号：US12594397

申请日：2008-04-04

申请人： Tsutomu Yuasa ,  Yuko Matsuda ,  Naohiko Itayama ,  Hideaki Nagano

发明人： Tsutomu Yuasa ,  Yuko Matsuda ,  Naohiko Itayama ,  Hideaki Nagano

IPC分类号： C07C41/03 ,  C08G65/26 ,  C08F216/14 ,  C08F220/06 ,  C08F216/12

CPC分类号： C08F216/125 ,  C08F216/1416 ,  C08F220/06 ,  C08G65/2609

摘要： To provide a production method of a (poly)alkylene glycol chain-containing polymer which can be preferably used in various applications such as an admixture for cement and which can exhibit extremely high dispersibility to a cement composition. The unsaturated (poly)alkylene glycol ether monomer of the present invention is an unsaturated (poly)alkylene glycol ether monomer production method for producing an unsaturated (poly)alkylene glycol ether monomer by addition reaction of an alkylene oxide on an unsaturated alcohol, wherein the production method includes a step of carrying out addition reaction under condition of existence of 0.01 to 25 parts by mass of an unsaturated (poly)alkylene glycol diether monomer to 100 parts by mass of the unsaturated alcohol, and a (poly)alkylene glycol chain-containing polymer production method, wherein a monomer component including an unsaturated (poly)alkylene glycol ether monomer produced by the production method.

摘要翻译： 提供一种（聚）亚烷基二醇链聚合物的制造方法，其可以优选用于各种用途，例如水泥混合物，并且可以显示出对水泥组合物极高的分散性。 本发明的不饱和（聚）亚烷基二醇醚单体是通过烯化氧在不饱和醇上的加成反应制备不饱和（聚）亚烷基二醇醚单体的不饱和（聚）亚烷基二醇醚单体制备方法，其中 制造方法包括在不饱和（聚）亚烷基二醇二醚单体的存在下，在存在0.01〜25质量份的不饱和醇的情况下进行加成反应的工序，和（聚） 其中含有通过该制造方法制造的不饱和（聚）亚烷基二醇醚单体的单体成分。

公开(公告)号：US06376703B1

公开(公告)日：2002-04-23

申请号：US09379068

申请日：1999-08-23

申请人： Hideaki Nagano

发明人： Hideaki Nagano

IPC分类号： C07C6952

CPC分类号： C07C213/10 ,  C07C219/08

摘要： The storage of alkylaminoalkyl (meth)acrylate is made in a container made of stainless steel whose wall surface has not more than 1.6 &mgr;m for the Ra defined in JIS B 0601. And the compound is stored in a container having a water concentration of not more than 0.1 vol. % and a molecular oxygen concentration exceeding 0 to 10 vol. % in the gas phase part of the container. When the compound is handled under these conditions, it is enabled to retain the (meth)acrylic acid concentration therein below 0.1 wt. %, prevented from producing a polymer or a precipitate, and precluded from coloration.

摘要翻译： （甲基）丙烯酸烷基氨基烷基酯的储存在JIS B 0601中定义的Ra的壁面不超过1.6μm的不锈钢容器中制备。将化合物储存在水分浓度不大的容器中 大于0.1体积 ％，分子氧浓度超过0〜10体积％。 容器的气相部分的％。当化合物在这些条件下处理时，能够将其中的（甲基）丙烯酸浓度保持在0.1重量％以下。 ％，防止产生聚合物或沉淀，并防止着色。