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    Strain-Promoted Crosslinking of PEG-based Hydrogels via Copper-Free Cycloaddition
    3.
    发明申请
    Strain-Promoted Crosslinking of PEG-based Hydrogels via Copper-Free Cycloaddition 审中-公开
    通过无铜环加成的PEG基水凝胶的应变促进交联

    公开(公告)号：US20150183988A1

    公开(公告)日：2015-07-02

    申请号：US14418507

    申请日：2013-07-31

    申请人： Matthew Becker ,  Robert A. Weiss

    发明人： Matthew Becker ,  Robert A. Weiss

    IPC分类号： C08L71/00 ,  C08L89/00

    CPC分类号： C08L71/00 ,  A61K9/06 ,  A61K47/34 ,  C08G65/325 ,  C08G65/33389 ,  C08L71/02 ,  C08L89/00 ,  C08L2205/02

    摘要： The present invention is directed to a covalently crosslinked hydrogel comprising the strain-promoted reaction product of an 8-member cycloalkyne functionalized polyalkylene glycol and a multi-arm glycerol exytholate triazide and methods for making them. Because the precursor materials can be manipulated without causing crosslinking, provided the strain threshold is not reached, these hydrogels permit mechanical control over when (and where) cross linking occurs and are easier to use than prior strain-activated or temperature-activated systems. These novel hydrogels do not require a catalyst to cross link, thus avoiding the biocompatibility problems common to many catalysts. Nor is the crosslinking process affected by the presence of catalysts or other substances, which have interfered with crosslinking in known strain induced hydrogels. Because of their crosslinking reaction kinetics, these novel hydrogels can encapsulate and transport highly sensitive cells and other biological additives and have no known toxic byproducts.

    摘要翻译： 本发明涉及一种共价交联的水凝胶，其包含8-元环炔官能化聚亚烷基二醇和多臂甘油异戊酸三叠氮化物的应变促进反应产物及其制备方法。 因为前体材料可以在不引起交联的情况下被操纵，只要未达到应变阈值，这些水凝胶允许机械控制何时发生交联（并且在何处发生），并且比以前的应变活化或温度激活的系统更容易使用。 这些新颖的水凝胶不需要催化剂交联，从而避免许多催化剂常见的生物相容性问题。 交联过程也不受催化剂或其他物质的存在的影响，这些物质干扰已知应变诱导的水凝胶中的交联。 由于它们的交联反应动力学，这些新颖的水凝胶可以包封和输送高敏感性细胞和其他生物添加剂，并且没有已知的有毒副产物。

    Methods For Advertising
    6.
    发明申请
    Methods For Advertising 审中-公开
    广告方法

    公开(公告)号：US20110166938A1

    公开(公告)日：2011-07-07

    申请号：US12984756

    申请日：2011-01-05

    申请人： Alexander Deridder ,  Matthew Becker ,  Stephen Moore

    发明人： Alexander Deridder ,  Matthew Becker ,  Stephen Moore

    IPC分类号： G06Q30/00

    CPC分类号： G06Q30/0261 ,  G06Q30/02

    摘要： A web conversion method based on phone calls is disclosed. Some embodiments comprise distributing a multiplicity of ads across a multiplicity of online media channels, displaying a unique advertiser phone number on each ad for a limited time every time a prospect visits a webpage hosting the ad, determining that the prospect called the advertiser phone number within the limited time, determining that the geographical zone of the prospect at the time of the call encompasses the geographical location of the IP address at where the unique phone number is displayed, and charging an advertiser for the ad that displayed the advertiser phone number.

    摘要翻译： 公开了一种基于电话呼叫的网页转换方法。 一些实施例包括在多个在线媒体频道上分配多个广告，每当潜在客户访问托管广告的网页时，在有限的时间内在每个广告上显示唯一的广告商电话号码，确定潜在客户称广告主电话号码在 在有限的时间内，确定呼叫时的潜在客户的地理区域包含显示唯一电话号码所在IP地址的地理位置，并向广告商收取显示广告主电话号码的广告。

    Signal modulation
    7.
    发明申请
    Signal modulation 失效
    信号调制

    公开(公告)号：US20050068885A1

    公开(公告)日：2005-03-31

    申请号：US10676565

    申请日：2003-09-30

    申请人： Matthew Becker ,  Karl Wyatt

    发明人： Matthew Becker ,  Karl Wyatt

    IPC分类号： H04J7/00 ,  H04L25/49 ,  H04L25/493 ,  H03C1/52 ,  H04J3/02

    CPC分类号： H04L25/4917 ,  H04J7/00 ,  H04L25/493

    摘要： According to an embodiment of the invention, a method and apparatus for signal modulation are described. According to an embodiment of the invention, a method comprises producing and transferring a modulated signal. The modulation of the signal is over a plurality of amplitude levels, including at least a first amplitude level, a second amplitude level and a third amplitude level, and over a plurality of time slots, including at least a first time slot, a second time slot, and a third time slot. The modulated signal transitions from the first amplitude level to the second amplitude level in the first phase slot, remains at the second amplitude level in the second time slot, and transitions from the second amplitude level to the third amplitude level in a third time slot.

    摘要翻译： 根据本发明的实施例，描述了用于信号调制的方法和装置。 根据本发明的实施例，一种方法包括产生和传送调制信号。 信号的调制在多个幅度水平上，包括至少第一幅度电平，第二幅度电平和第三幅度电平以及多个时隙，包括至少第一时隙，第二时间 插槽和第三个时隙。 调制信号从第一相位时隙中的第一幅度电平转换到第二幅度电平在第二时隙中保持在第二幅度电平，并且在第三时隙中从第二幅度电平转变到第三幅度电平。

    Black box timing model for latch-based systems
    8.
    发明授权
    Black box timing model for latch-based systems 失效
    基于闩锁的系统的黑盒时序模型

    公开(公告)号：US06701498B2

    公开(公告)日：2004-03-02

    申请号：US10008930

    申请日：2001-11-08

    申请人： Matthew Becker ,  Chen Li Lin

    发明人： Matthew Becker ,  Chen Li Lin

    IPC分类号： G06F1750

    CPC分类号： G06F17/5031

    摘要： A method of creating a black box timing model for a digital circuit. The digital circuit is characterized by a block model having at least one input and at least one output. The method determines a delay statement for the output of the block model. The method also determines an input set-up constraint for the input of the block model. The input set-up constraint is based upon the delay statement. The model is then used with a static timing analyzer to accurately model a flow-through circuit.

    摘要翻译： 一种为数字电路创建黑匣子时序模型的方法。 数字电路的特征在于具有至少一个输入和至少一个输出的块模型。 该方法确定块模型的输出的延迟语句。 该方法还确定块模型的输入的输入设置约束。 输入设置约束基于delay语句。 然后将该模型与静态定时分析仪一起使用以精确地建模流通电路。

    Path filtering for latch-based systems
    9.
    发明授权
    Path filtering for latch-based systems 有权
    基于锁存器的系统的路径过滤

    公开(公告)号：US06611949B2

    公开(公告)日：2003-08-26

    申请号：US10007560

    申请日：2001-11-08

    申请人： Matthew Becker ,  Eileen You

    发明人： Matthew Becker ,  Eileen You

    IPC分类号： G06F945

    CPC分类号： G06F17/5031

    摘要： A method and a system for static timing analysis of a latch-based circuit. A netlist data structure represents the latch-based circuit. The method statically analyzes the netlist data structure and produces timing information for signal paths within the latch-based circuit. The signal paths are filtered using path termination information, which specifies where paths end. The path termination information distinguishes a first signal path that terminates at a latch from a second signal path that flows through that same latch.

    摘要翻译： 一种用于基于锁存器电路的静态时序分析的方法和系统。 网表数据结构表示基于锁存器的电路。 该方法静态分析网表数据结构，并为基于锁存器的电路中的信号路径产生定时信息。 使用路径终止信息来过滤信号路径，该信息指定路径在哪里结束。 路径终止信息区分在锁存器处终止的第一信号路径与流过同一锁存器的第二信号路径。