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    Strain-Promoted Crosslinking of PEG-based Hydrogels via Copper-Free Cycloaddition
    3.
    发明申请
    Strain-Promoted Crosslinking of PEG-based Hydrogels via Copper-Free Cycloaddition 审中-公开
    通过无铜环加成的PEG基水凝胶的应变促进交联

    公开(公告)号：US20150183988A1

    公开(公告)日：2015-07-02

    申请号：US14418507

    申请日：2013-07-31

    申请人： Matthew Becker ,  Robert A. Weiss

    发明人： Matthew Becker ,  Robert A. Weiss

    IPC分类号： C08L71/00 ,  C08L89/00

    CPC分类号： C08L71/00 ,  A61K9/06 ,  A61K47/34 ,  C08G65/325 ,  C08G65/33389 ,  C08L71/02 ,  C08L89/00 ,  C08L2205/02

    摘要： The present invention is directed to a covalently crosslinked hydrogel comprising the strain-promoted reaction product of an 8-member cycloalkyne functionalized polyalkylene glycol and a multi-arm glycerol exytholate triazide and methods for making them. Because the precursor materials can be manipulated without causing crosslinking, provided the strain threshold is not reached, these hydrogels permit mechanical control over when (and where) cross linking occurs and are easier to use than prior strain-activated or temperature-activated systems. These novel hydrogels do not require a catalyst to cross link, thus avoiding the biocompatibility problems common to many catalysts. Nor is the crosslinking process affected by the presence of catalysts or other substances, which have interfered with crosslinking in known strain induced hydrogels. Because of their crosslinking reaction kinetics, these novel hydrogels can encapsulate and transport highly sensitive cells and other biological additives and have no known toxic byproducts.

    摘要翻译： 本发明涉及一种共价交联的水凝胶，其包含8-元环炔官能化聚亚烷基二醇和多臂甘油异戊酸三叠氮化物的应变促进反应产物及其制备方法。 因为前体材料可以在不引起交联的情况下被操纵，只要未达到应变阈值，这些水凝胶允许机械控制何时发生交联（并且在何处发生），并且比以前的应变活化或温度激活的系统更容易使用。 这些新颖的水凝胶不需要催化剂交联，从而避免许多催化剂常见的生物相容性问题。 交联过程也不受催化剂或其他物质的存在的影响，这些物质干扰已知应变诱导的水凝胶中的交联。 由于它们的交联反应动力学，这些新颖的水凝胶可以包封和输送高敏感性细胞和其他生物添加剂，并且没有已知的有毒副产物。

    Endovenous closure of varicose veins with mid infrared laser
    5.
    发明授权
    Endovenous closure of varicose veins with mid infrared laser 有权
    用中红外激光静脉闭合静脉曲张

    公开(公告)号：US07524316B2

    公开(公告)日：2009-04-28

    申请号：US10982504

    申请日：2004-11-04

    申请人： David R. Hennings ,  Mitchel P. Goldman ,  Robert A. Weiss ,  Eric B. Taylor ,  Don Johnson ,  Ignacio Cespedes

    发明人： David R. Hennings ,  Mitchel P. Goldman ,  Robert A. Weiss ,  Eric B. Taylor ,  Don Johnson ,  Ignacio Cespedes

    IPC分类号： A61B18/18

    CPC分类号： A61B18/24 ,  A61B2017/00084 ,  A61B2018/00005 ,  A61B2018/00196 ,  A61B2018/2261 ,  A61B2090/036

    摘要： This invention is an improved method and device for treating varicose veins 200 or the greater saphenous vein 202. The method comprises the use of infrared laser radiation in the region of 1.2 to 2.2 um in a manner from inside the vessel 200 or 202 such that the endothelial cells of the vessel wall 704 are damaged and collagen fibers in the vessel wall 704 are heated to the point where they permanently contract, the vessel 200 or 202 is occluded and ultimately resorbed. The device includes a laser 102 delivered via a fiber optic catheter 300 that may have frosted or diffusing fiber tips 308, or that may be provided with a protective spacer. A motorized pull back device 104 may be used, and a thermal sensor 600 may be used to help control the power required to maintain the proper treatment temperature.

    摘要翻译： 本发明是用于治疗静脉曲张200或较大隐静脉202的改进方法和装置。该方法包括以1.2至2.2μm的范围使用红外激光辐射，从容器200或202内部的方式使得 血管壁704的内皮细胞被破坏，血管壁704中的胶原纤维被加热到它们永久收缩的位置，血管200或202被封闭并最终吸收。 该装置包括通过可以具有磨砂或漫射纤维尖端308的光纤导管300传送的激光器102，或者可以设置有保护隔离物的激光器102。 可以使用电动拉回装置104，并且可以使用热传感器600来帮助控制维持适当处理温度所需的功率。

    SHAPE MEMORY POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND USES THEREOF
    6.
    发明申请
    SHAPE MEMORY POLYMER COMPOSITIONS, METHOD OF MANUFACTURE, AND USES THEREOF 审中-公开
    形状记忆聚合物组合物，制造方法及其用途

    公开(公告)号：US20080287582A1

    公开(公告)日：2008-11-20

    申请号：US12112067

    申请日：2008-04-30

    申请人： Robert A. Weiss

    发明人： Robert A. Weiss

    IPC分类号： C08K5/09

    CPC分类号： C08K5/09 ,  C08K5/0091 ,  C08L23/32

    摘要： A shape memory composition includes an ionomeric elastomer and a low molecular weight additive that forms crystalline domains in the elastomeric ionomer. The amount of additive is effective to provide crystalline domains of a size and distribution effective to provide shape memory to the composition.

    摘要翻译： 形状记忆组合物包括离聚物弹性体和在弹性体离聚物中形成结晶域的低分子量添加剂。 添加剂的量有效地提供尺寸和分布的结晶域，以有效地为组合物提供形状记忆。

    Golf ball cover compositions
    8.
    发明授权
    Golf ball cover compositions 失效
    高尔夫球罩组合物

    公开(公告)号：US06350815B1

    公开(公告)日：2002-02-26

    申请号：US09634412

    申请日：2000-08-08

    申请人： Michael J. Sullivan ,  Robert A. Weiss

    发明人： Michael J. Sullivan ,  Robert A. Weiss

    IPC分类号： C08L3302

    CPC分类号： C08L23/08 ,  A63B37/0003 ,  A63B37/0024 ,  C08L23/0869 ,  C08L23/0876 ,  C08L51/00 ,  C08L2205/02 ,  Y10S273/04 ,  Y10S273/22 ,  C08L2666/02 ,  C08L2666/06 ,  C08L2666/04

    摘要： The present invention is directed to golf ball cover compositions containing blends of high or low carboxylic acid based copolymers and ethylene copolymers such as ethylene alkyl acrylates. The carboxylic acid groups of the blends are neutralized with metal cations. Golf balls produced with the cover molded thereon exhibit desired properties of distance and high coefficient of restitution without substantially sacrificing and/or improving characteristics like playability and durability when compared to existing covers comprising ionomeric resin blends.

    摘要翻译： 本发明涉及包含高或低羧酸基共聚物和乙烯共聚物如丙烯酸烷基酯的共混物的高尔夫球覆盖物组合物。 共混物的羧酸基团被金属阳离子中和。 与现有的包含离聚物树脂混合物的覆盖物相比，用其上模塑的覆盖物制成的高尔夫球具有所需的距离性​​能和高恢复系数，而基本上不会牺牲和/或改善诸如可玩性和耐久性的特性。

    Conductive elastomeric foams by in-situ vapor phase polymerization of pyrroles
    9.
    发明授权
    Conductive elastomeric foams by in-situ vapor phase polymerization of pyrroles 失效
    导电弹性泡沫通过原位气相聚合的吡咯

    公开(公告)号：US6156235A

    公开(公告)日：2000-12-05

    申请号：US188513

    申请日：1998-11-09

    申请人： Michael D. Bessette ,  Robert A. Weiss ,  Poh Poh Gan ,  Can Erkey ,  Yueping Fu

    发明人： Michael D. Bessette ,  Robert A. Weiss ,  Poh Poh Gan ,  Can Erkey ,  Yueping Fu

    IPC分类号： C08J9/42 ,  H01B1/12 ,  H01B1/06 ,  C08J9/36

    CPC分类号： C08J9/42 ,  H01B1/127 ,  H01B1/128 ,  C08J2203/08 ,  C08J2323/02 ,  C08J2327/06 ,  C08J2375/04 ,  C08J2439/00

    摘要： A conductive elastomeric foam composite is presented, comprising an elastomer foam and polypyrrole, thiophene, or aniline and derivatives thereof. The foam is manufactured by first diffusing an oxidant into the dense polymer phase of a solvent-swollen foam and then diffusing pyrrole or pyrrole derivative vapor or solution into the dried foam, resulting in an in situ chemical oxidative polymerization of pyrrole at the oxidant site. Only about 5 wt % of conductive polymer is required for observing an insulator to conductor transition. The conductivity of the composite foam can be effectively controlled between 10.sup.-7 and 10.sup.-1 S/cm by varying either the amount of oxidant used and/or the copolymer composition.

    摘要翻译： 提出了一种导电弹性体泡沫复合材料，其包含弹性体泡沫和聚吡咯，噻吩或苯胺及其衍生物。 通过首先将氧化剂扩散到溶剂溶胀泡沫的致密聚合物相中，然后将吡咯或吡咯衍生物蒸气或溶液扩散到干燥的泡沫中，从而在氧化剂位置进行吡咯的原位化学氧化聚合来制造泡沫体。 只有约5重量％的导电聚合物才能观察绝缘体到导体的转变。 通过改变所使用的氧化剂的量和/或共聚物组成，复合泡沫体的电导率可以有效地控制在10-7和10-1S / cm之间。