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    High efficiency balanced detection interferometer
    5.
    发明申请
    High efficiency balanced detection interferometer 有权
    高效平衡检测干涉仪

    公开(公告)号：US20060109477A1

    公开(公告)日：2006-05-25

    申请号：US11264871

    申请日：2005-11-02

    申请人： Yan Zhou ,  Matthew Everett ,  Martin Hacker

    发明人： Yan Zhou ,  Matthew Everett ,  Martin Hacker

    IPC分类号： G01B9/02

    CPC分类号： G01B9/02091 ,  G01B2290/40

    摘要： An interferometer configured for use in optical coherence domain (OCT) reflectometry systems is disclosed. In the preferred embodiments, efficient routing of light and a balanced detection arrangement provide a high signal to noise ratio. In a first set of embodiments, a 3×3 coupler is used to split light along separate sample and reference paths and also for combining light returning from those paths and supplying the interfered collected light to the detection system. In an alternate set of embodiments, a pair of cascaded 2×2 couplers provides a similar function. The interferometer can be used with various OCT modalities including time-domain and frequency domain approaches.

    摘要翻译： 公开了一种配置用于光学相干域（OCT）反射系统的干涉仪。 在优选实施例中，光的有效路由和平衡检测装置提供高的信噪比。 在第一组实施例中，使用3x3耦合器沿独立的采样和参考路径分离光，并且还用于组合从那些路径返回的光并将受干扰的收集的光提供给检测系统。 在另一组实施例中，一对级联的2x2耦合器提供类似的功能。 干涉仪可以与各种OCT模式一起使用，包括时域和频域方法。

    Patterned spinning disk based optical phase shifter for spectral domain optical coherence tomography
    6.
    发明申请
    Patterned spinning disk based optical phase shifter for spectral domain optical coherence tomography 失效
    用于光谱相干层析成像的基于旋转圆盘的光学移相器

    公开(公告)号：US20060072424A1

    公开(公告)日：2006-04-06

    申请号：US10933795

    申请日：2004-09-03

    申请人： Matthew Everett ,  Scott Meyer ,  Yan Zhou

    发明人： Matthew Everett ,  Scott Meyer ,  Yan Zhou

    IPC分类号： G11B7/135

    CPC分类号： A61B3/102 ,  A61B3/1005 ,  G01B9/02012 ,  G01B9/02044 ,  G01B9/02049 ,  G01B9/02069 ,  G01B9/02091 ,  G01B2290/35

    摘要： A low cost patterned spinning disk is disclosed for achieving relatively rapid discrete optical phase shifts for an optical beam. The invention is particularly useful in a spectral domain optical coherence tomography system. The disk contains stepped patterns of different heights and/or refractive index distribution such that as it spins, an optical beam passing through or being reflected by the disk will experience different discrete optical phase delays. The disk can be operated as a phase shifter or it can be operated in synchronization with an intensity modulating chopper disk or a direct intensity modulation of the light source. The disk can also contain intensity modulating patterns such that both phase shifting and intensity modulation can be achieved at the same time. Various possible methods are also disclosed for the fabrication of the disk.

    摘要翻译： 公开了一种低成本图案旋转盘，用于实现光束的相对快速的离散光学相移。 本发明在频域光学相干断层摄影系统中特别有用。 盘包含不同高度和/或折射率分布的阶梯图案，使得当其旋转时，通过或被盘反射的光束将经历不同的离散光学相位延迟。 磁盘可以作为移相器来操作，或者可以与强度调制斩波盘同步操作，也可以与光源进行直接强度调制。 磁盘还可以包含强度调制模式，使得可以同时实现相移和强度调制。 还公开了用于制造盘的各种可能的方法。

    Method of bioimage data processing for revealing more meaningful anatomic features of diseased tissues
    7.
    发明申请
    Method of bioimage data processing for revealing more meaningful anatomic features of diseased tissues 有权
    生物图像数据处理方法，用于揭示病变组织的更有意义的解剖特征

    公开(公告)号：US20070103693A1

    公开(公告)日：2007-05-10

    申请号：US11223549

    申请日：2005-09-09

    申请人： Matthew Everett ,  Scott Meyer ,  Paul Stetson ,  Yan Zhou

    发明人： Matthew Everett ,  Scott Meyer ,  Paul Stetson ,  Yan Zhou

    IPC分类号： G01B9/02 ,  G06K9/00 ,  A61B5/05 ,  A61B5/103

    CPC分类号： A61B5/0066 ,  G06T7/0014 ,  G06T19/00 ,  G06T2200/24 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2210/41

    摘要： The present invention discloses a method for generating elevation maps or images of a tissue layer/boundary with respect to a fitted reference surface, comprising the steps of finding and segmenting a desired tissue layer/boundary; fitting a smooth reference surface to the segmented tissue layer/boundary; calculating elevations of the same or other tissue layer/boundary relative to the fitted reference surface; and generating maps of elevation relative to the fitted surface. The elevation can be displayed in various ways including three-dimensional surface renderings, topographical contour maps, contour maps, en-face color maps, and en-face grayscale maps. The elevation can also be combined and simultaneously displayed with another tissue layer/boundary dependent set of image data to provide additional information for diagnostics.

    摘要翻译： 本发明公开了一种用于产生相对于拟合的参考表面的组织层/边界的仰角图或图像的方法，包括以下步骤：找到并分割所需的组织层/边界; 将平滑的参考表面拟合到分段的组织层/边界; 计算相对于拟合参考表面的相同或其它组织层/边界的高度; 并产生相对于拟合表面的高程图。 高程可以以各种方式显示，包括三维表面效果图，地形轮廓图，轮廓图，面孔颜色图和面对灰度图。 也可以将高程组合并同时显示另一个组织层/边界依赖的图像数据集，以提供用于诊断的附加信息。

    Optical coherence tomography for eye-length measurement
    8.
    发明申请
    Optical coherence tomography for eye-length measurement 有权
    光学相干断层扫描用于眼睛测量

    公开(公告)号：US20070076217A1

    公开(公告)日：2007-04-05

    申请号：US11243665

    申请日：2005-10-05

    申请人： Chris Baker ,  Matthew Everett ,  Yan Zhou ,  Keith O'Hara

    发明人： Chris Baker ,  Matthew Everett ,  Yan Zhou ,  Keith O'Hara

    IPC分类号： G01B11/02

    CPC分类号： A61B3/102 ,  A61B3/1005 ,  A61B5/0066

    摘要： An accurate measure of eye length can be obtained using concurrent OCT measurements. A position OCT device can be used to continually monitor the position of the front surface of the cornea, while a distance OCT device can determine the apparent distance between the front surface of the cornea and the front surface of the retina. Since the eye is likely to move during the period of time between measurements of the cornea and retina, the monitored position of the cornea can be used to correct the apparent length measurement by the amount of eye movement over that period of time, in order to obtain an accurate measure of eye length. In some embodiments a single OCT device can serve the dual role of monitoring eye position while making eye length measurements

    摘要翻译： 使用并行OCT测量可以获得眼睛长度的精确测量。 位置OCT装置可以用于连续监视角膜前表面的位置，而距离OCT装置可以确定角膜前表面和视网膜的前表面之间的表观距离。 由于眼睛可能在角膜和视网膜的测量之间的时间段期间移动，所以可以使用角膜的监视位置来校正视力长度测量量在该时间段内的眼睛移动量，以便 获得眼睛长度的准确度量。 在一些实施例中，单个OCT设备可以起到监视眼睛位置的双重作用，同时进行眼睛长度测量

    Optical coherence domain reflectometry guidewire
    9.
    发明授权
    Optical coherence domain reflectometry guidewire 失效
    光学相干畴反射导丝

    公开(公告)号：US06175669B1

    公开(公告)日：2001-01-16

    申请号：US09050571

    申请日：1998-03-30

    申请人： Billy W. Colston ,  Matthew Everett ,  Luiz B. Da Silva ,  Dennis Matthews

    发明人： Billy W. Colston ,  Matthew Everett ,  Luiz B. Da Silva ,  Dennis Matthews

    IPC分类号： G02B600

    CPC分类号： A61B5/6852 ,  A61B1/00177 ,  A61B1/00181 ,  A61B5/0066 ,  A61B5/0084

    摘要： A guidewire with optical sensing capabilities is based on a multiplexed optical coherence domain reflectometer (OCDR), which allows it to sense location, thickness, and structure of the arterial walls or other intra-cavity regions as it travels through the body during minimally invasive medical procedures. This information will be used both to direct the guidewire through the body by detecting vascular junctions and to evaluate the nearby tissue. The guidewire contains multiple optical fibers which couple light from the proximal to distal end. Light from the fibers at the distal end of the guidewire is directed onto interior cavity walls via small diameter optics such as gradient index lenses and mirrored corner cubes. Both forward viewing and side viewing fibers can be included. The light reflected or scattered from the cavity walls is then collected by the fibers, which are multiplexed at the proximal end to the sample arm of an optical low coherence reflectometer. The guidewire can also be used in nonmedical applications.

    摘要翻译： 具有光学感测能力的导丝基于多路复用光学相干域反射计（OCDR），其允许其在微创医疗中穿过身体时感测动脉壁或其他腔内区域的位置，厚度和结构 程序。 该信息将用于通过检测血管结点引导导线穿过身体并评估附近的组织。 导丝包含多个光纤，其将光从近端耦合到远端。 来自导线远端的纤维的光通过诸如梯度折射率透镜和镜像角立方体的小直径光学器件引导到内腔壁上。 可以包括前视和侧视纤维。 然后从空腔壁反射或散射的光被纤维收集，纤维在近端被多路复用到光学低相干反射计的样品臂。 导丝也可用于非医疗应用。

    Methods and apparatus for management and analysis of costs and savings
    10.
    发明申请
    Methods and apparatus for management and analysis of costs and savings 有权
    用于管理和分析成本和储蓄的方法和设备

    公开(公告)号：US20060259310A1

    公开(公告)日：2006-11-16

    申请号：US11128640

    申请日：2005-05-13

    申请人： Matthew Everett ,  Supriya Mandava

    发明人： Matthew Everett ,  Supriya Mandava

    IPC分类号： G06Q99/00 ,  G07G1/00 ,  H04M3/51 ,  G06F17/30

    CPC分类号： G06Q30/02 ,  G06Q30/0206 ,  G06Q30/0283

    摘要： Systems and techniques for management and analysis of cost and savings information. Products sold by an enterprise, and the components used in the creation of those products are identified. Transaction data relating to purchases of components by the enterprise is gathered from various sources and used to generate cost information for the components. The cost information is compared to baseline cost information to compute savings information for the components. Specifications of components used in products, information relating to the number of products created and sold and information categorizing components and products is used to generate cost and savings information for components, products and categories of products.

    摘要翻译： 用于管理和分析成本和储蓄信息的系统和技术。 确定企业销售的产品，以及用于创建这些产品的组件。 与企业采购组件相关的交易数据从各种来源收集，用于生成组件的成本信息。 将成本信息与基准成本信息进行比较，以计算组件的储蓄信息。 产品中使用的部件规格，与创建和销售的产品数量相关的信息以及组件和产品分类信息用于生成组件，产品和产品类别的成本和储蓄信息。