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1.发明授权Devices, therapeutic compositions and corresponding percutaneous treatment methods for aortic dissection 有权用于主动脉夹层的装置，治疗组合物和相应的经皮治疗方法公开(公告)号：US08911468B2
公开(公告)日：2014-12-16
申请号：US13362492
申请日：2012-01-31
CPC分类号： A61B17/12109 , A61B17/00491 , A61B17/12036 , A61B17/12181 , A61B17/12195 , A61B2017/22067
摘要： The methods and devices disclosed herein pertain to the percutaneous treatment of various forms of aortic dissection by at least partially filling the false lumen of the aortic dissection with a stabilization agent percutaneously and steps to decrease the size of the false lumen using the devices. Fluid maybe aspirated from the false lumen to decrease the volume of the false lumen. And the entrance opening between the true lumen and the false lumen may be sealed with a sealing agent such as a biocompatible adhesive. The medical devices disclosed herein generally comprise an extendable sealing element that is used in conjunction with a catheter to expand the true lumen while reducing the size of the false lumen. The device has the ability to aspirate and/or deliver fluid containing the stabilization agent into the false lumen.
摘要翻译： 本文公开的方法和装置涉及通过至少部分地用稳定剂经皮肤填充主动脉夹层的假腔以及使用该装置减少假腔的尺寸的步骤来经皮治疗各种形式的主动脉夹层。 流体可能从假腔吸出，以减少假腔的体积。 并且真空腔和假腔之间的入口可以用诸如生物相容性粘合剂的密封剂密封。 本文公开的医疗装置通常包括可延伸的密封元件，其与导管结合使用以在减少假腔的尺寸的同时扩张真腔。 该装置具有将含有稳定剂的流体吸入和/或输送到假腔中的能力。
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2.发明申请DEVICES, THERAPEUTIC COMPOSITIONS AND CORRESPONDING PERCUTANEOUS TREATMENT METHODS FOR AORTIC DISSECTION 有权装置，治疗组合物和相应的治疗方法进行动态切除公开(公告)号：US20120197284A1
公开(公告)日：2012-08-02
申请号：US13362492
申请日：2012-01-31
CPC分类号： A61B17/12109 , A61B17/00491 , A61B17/12036 , A61B17/12181 , A61B17/12195 , A61B2017/22067
摘要： The methods and devices disclosed herein pertain to the percutaneous treatment of various forms of aortic dissection by at least partially filling the false lumen of the aortic dissection with a stabilization agent percutaneously and steps to decrease the size of the false lumen using the devices. Fluid maybe aspirated from the false lumen to decrease the volume of the false lumen. And the entrance opening between the true lumen and the false lumen may be sealed with a sealing agent such as a biocompatible adhesive. The medical devices disclosed herein generally comprise an extendable sealing element that is used in conjunction with a catheter to expand the true lumen while reducing the size of the false lumen. The device has the ability to aspirate and/or deliver fluid containing the stabilization agent into the false lumen.
摘要翻译： 本文公开的方法和装置涉及通过至少部分地用稳定剂经皮肤填充主动脉夹层的假腔以及使用该装置减少假腔的尺寸的步骤来经皮治疗各种形式的主动脉夹层。 流体可能从假腔吸出，以减少假腔的体积。 并且真空腔和假腔之间的入口可以用诸如生物相容性粘合剂的密封剂密封。 本文公开的医疗装置通常包括可延伸的密封元件，其与导管结合使用以在减少假腔的尺寸的同时扩张真腔。 该装置具有将含有稳定剂的流体吸入和/或输送到假腔中的能力。
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公开(公告)号：US20120323211A1
公开(公告)日：2012-12-20
申请号：US13474342
申请日：2012-05-17
CPC分类号： A61K47/32 , A61K31/11 , A61K31/7024 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/16 , A61L2300/102 , A61M25/1011 , A61M25/104 , A61M2025/105 , A61M2025/1052 , A61M2025/1075 , A61M2025/1086 , A61M2025/1097 , F04C2270/0421 , A61K2300/00 , C08L75/04 , C08L29/04
摘要： A coated balloon device for stabilizing a section of a blood vessel in a living subject is disclosed. The coating layer of the coated balloon comprises a phenolic compound having a plurality of phenolic groups connected to form a hydrophobic core with peripheral phenolic hydroxyl groups. The coating layer of the coated balloon may contain a hydrophilic polymer to facilitate the release of the phenolic compound. The balloon in general is made of a compliant polymer for atraumatic contact with the blood vessel. In some embodiments, the coating of the coated balloon device further comprises a hydrophilic undercoat layer between the balloon and the coating layer. In some embodiments, the coated balloon device further comprises a sacrificial top coating that dissolves upon delivery into the section of the blood vessel and comprises a hydrophilic composition including sugar, sugar derivatives, or a combination thereof.
摘要翻译： 公开了一种用于稳定活体中的血管的一部分的涂覆球囊装置。 涂覆球囊的涂层包含具有连接以形成具有外部酚羟基的疏水性核心的多个酚基的酚类化合物。 涂覆的球囊的涂层可以含有亲水性聚合物以促进酚类化合物的释放。 气囊通常由与血管无创接触的顺应性聚合物制成。 在一些实施方案中，涂覆的球囊装置的涂层还包括在球囊和涂层之间的亲水性底涂层。 在一些实施例中，涂覆的球囊装置还包括牺牲顶部涂层，其在递送到血管的部分中时溶解，并且包括包含糖，糖衍生物或其组合的亲水性组合物。
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公开(公告)号：US09937255B2
公开(公告)日：2018-04-10
申请号：US13474342
申请日：2012-05-17
IPC分类号： A61L29/08 , A61K47/32 , A61K31/11 , A61K31/7024 , A61L29/06 , A61L29/14 , A61L29/16 , A61M25/10
CPC分类号： A61K47/32 , A61K31/11 , A61K31/7024 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/16 , A61L2300/102 , A61M25/1011 , A61M25/104 , A61M2025/105 , A61M2025/1052 , A61M2025/1075 , A61M2025/1086 , A61M2025/1097 , F04C2270/0421 , A61K2300/00 , C08L75/04 , C08L29/04
摘要： A coated balloon device for stabilizing a section of a blood vessel in a living subject is disclosed. The coating layer of the coated balloon comprises a phenolic compound having a plurality of phenolic groups connected to form a hydrophobic core with peripheral phenolic hydroxyl groups. The coating layer of the coated balloon may contain a hydrophilic polymer to facilitate the release of the phenolic compound. The balloon in general is made of a compliant polymer for atraumatic contact with the blood vessel. In some embodiments, the coating of the coated balloon device further comprises a hydrophilic undercoat layer between the balloon and the coating layer. In some embodiments, the coated balloon device further comprises a sacrificial top coating that dissolves upon delivery into the section of the blood vessel and comprises a hydrophilic composition including sugar, sugar derivatives, or a combination thereof.
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公开(公告)号：US08382796B2
公开(公告)日：2013-02-26
申请号：US12626175
申请日：2009-11-25
申请人： David J. Blaeser , Jerome K. Grudem, Jr. , Scott A. Olson , Mark R. Christianson , Scott M. Hanson , Edward J. Anderson , Patrick P. Russo , Dennis W. Wahr
发明人： David J. Blaeser , Jerome K. Grudem, Jr. , Scott A. Olson , Mark R. Christianson , Scott M. Hanson , Edward J. Anderson , Patrick P. Russo , Dennis W. Wahr
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： A device for sealing a patent foramen ovale (PFO) in the heart is provided. The device includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and an elongate member adapted to extend through the passageway and connect the left and right atrial anchors. The right atrial anchor preferably includes a plurality of arms and a cover attached to the arms. The left atrial anchor preferably also includes a plurality of arms and preferably does not include a cover. Preferably, the elongate member has a first end fixedly connected to the left atrial anchor and a portion, proximal to the first end, passing through the right atrial anchor. Preferably, the elongate member is flexible.
摘要翻译： 提供了一种用于密封心脏中卵圆孔（PFO）的装置。 该装置包括适于放置在心脏的左心房的左心房锚，适于放置在心脏右心房的右心房锚，以及适于延伸通过该通道并连接左心室和/ 右心房锚 右心房锚优选地包括多个臂和附接到臂的盖。 左心房锚固件优选地还包括多个臂，并且优选地不包括盖。 优选地，细长构件具有固定地连接到左心房锚的第一端和靠近第一端的部分，穿过右心房锚。 优选地，细长构件是柔性的。
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公开(公告)号：US07261950B2
公开(公告)日：2007-08-28
申请号：US10521827
申请日：2003-08-15
IPC分类号： B32B15/04 , B32B15/08 , B32B15/082 , H05K9/00
CPC分类号： H05K9/0094 , Y10T428/12396 , Y10T428/12569 , Y10T428/12896 , Y10T428/13 , Y10T428/24967 , Y10T428/24975 , Y10T428/26 , Y10T428/265 , Y10T428/31678 , Y10T428/31688 , Y10T428/31692
摘要： Electrically conductive films comprising a flexible support, an extensible metal or metal alloy layer, and a crosslinked polymeric protective layer have at least one permanently deformed curved region. The films can be light transmissive and can have regions of compound curvature, and the metal or metal alloy layer can be substantially continuous. The films have reduced susceptibility to fracture or corrosion compared to commercially available electromagnetic interference (EMI) shielding films.
摘要翻译： 包括柔性支撑体，可延展金属或金属合金层以及交联聚合物保护层的导电膜具有至少一个永久变形的弯曲区域。 膜可以是透光的并且可以具有复合曲率的区域，并且金属或金属合金层可以是基本上连续的。 与市售的电磁干扰（EMI）屏蔽膜相比，这些膜具有降低的断裂或腐蚀敏感性。
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公开(公告)号：US5482548A
公开(公告)日：1996-01-09
申请号：US328227
申请日：1994-10-25
IPC分类号： C01B13/14 , C01G23/04 , C09B67/18 , C09B67/20 , C09B67/22 , C09B67/36 , C09D11/00 , C09D11/02 , C09B41/00
CPC分类号： C09D11/037 , C09B67/002 , C09B67/0033
摘要： The present invention provides a pigment composition comprising a diarylide pigment, a monoprimary amine, a diprimary amine and an inorganic compound having active oxide or hydroxide surfaces.
摘要翻译： 本发明提供一种颜料组合物，其包含二芳基颜料，单原子胺，二原子胺和具有活性氧化物或氢氧化物表面的无机化合物。
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公开(公告)号：US3940959A
公开(公告)日：1976-03-02
申请号：US525292
申请日：1974-11-20
CPC分类号： E05B73/00 , B62D43/007 , B62D43/02 , Y10T70/5987
摘要： A locking device for spare tires which includes a specially formed mounting post for the tire, a base plate for the post, a locking disk engaging the tire and a lock fitted on the post to hold the disc and tire securely.
摘要翻译： 用于备用轮胎的锁定装置，其包括用于轮胎的特殊形成的安装柱，用于柱的基板，与轮胎接合的锁定盘和安装在柱上以锁定盘和轮胎的锁定。
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9.发明授权公开(公告)号：US08372112B2
公开(公告)日：2013-02-12
申请号：US10934735
申请日：2004-09-07
申请人： Mark R. Christianson , Scott A. Olson , Edward J. Anderson , Philip J. Haarstad , Douglas J. Krone , Dennis W. Wahr , David J. Blaeser
发明人： Mark R. Christianson , Scott A. Olson , Edward J. Anderson , Philip J. Haarstad , Douglas J. Krone , Dennis W. Wahr , David J. Blaeser
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/22032 , A61B17/221 , A61B90/39 , A61B2017/00243 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623 , A61B2017/2215 , A61F2002/011
摘要： A closure device for sealing a patent foramen ovale (PFO) in the heart includes a left atrial anchor adapted to be placed in a left atrium of the heart, a right atrial anchor adapted to be placed in a right atrium of the heart, and a flexible elongate member adapted to extend through the passageway and connect the left and right atrial anchors. A delivery system for delivering the closure device includes a lock push tube for moving a lock along the elongate member and a wire release tube surrounding a wire for controlling movement of the right atrial anchor along the elongate member. The lock push tube and the wire release tube extend in a side-by-side relationship. A handle includes knobs for controlling the lock push tube and the wire. A device for retrieving a mis-deployed closure device includes a shaft portion and an expandable retrieval portion.
摘要翻译： 用于密封心脏中卵圆孔（PFO）的闭合装置包括适于放置在心脏左心房的左心房锚，适于置于心脏右心房的右心房锚， 柔性细长构件适于延伸穿过通道并连接左心房和右心房。 用于输送闭合装置的输送系统包括用于沿着细长构件移动锁的锁定推动管和围绕线的线释放管，用于控制沿着细长构件的右心房锚的运动。 锁定推动管和导线释放管以并排的关系延伸。 手柄包括用于控制锁定推动管和线的旋钮。 用于检索错误展开的闭合装置的装置包括轴部分和可扩张的回缩部分。
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公开(公告)号：US20090178365A1
公开(公告)日：2009-07-16
申请号：US12408502
申请日：2009-03-20
摘要： A precast concrete meter pit consisting of an elongated hollow pipe having a beveled support ledge at one end and notches at the opposite end is fabricated by utilizing a slip form packerhead apparatus in which the beveled support ledge is formed by a radially inwardly inclined trowel edge bearing against a pallet member which is caused to vibrate when concrete is injected into the slip form apparatus.
摘要翻译： 一个预制混凝土仪表坑由一个细长的中空管组成，该中空管在一端具有一个倾斜的支撑凸缘，在另一端具有凹口，通过使用一种滑动式打包头装置来制造，其中斜面支撑凸缘由径向向内倾斜的t刀边缘轴承 抵靠当混凝土注入到滑动装置中时使其振动的托盘构件。
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