METHOD AND DEVICE FOR CONVEYING FLUIDS INTO THE TREATMENT UNIT OF A MEDICAL TREATMENT APPARATUS, IN PARTICULAR INTO THE DIALYZER OF A DIALYSIS APPARATUS
    1.
    发明申请
    METHOD AND DEVICE FOR CONVEYING FLUIDS INTO THE TREATMENT UNIT OF A MEDICAL TREATMENT APPARATUS, IN PARTICULAR INTO THE DIALYZER OF A DIALYSIS APPARATUS 有权
    用于将流体输送到医疗处理装置的处理单元中的方法和装置,特别是进入DIALYSIS装置的DIALYZER

    公开(公告)号:US20130087210A1

    公开(公告)日:2013-04-11

    申请号:US13703691

    申请日:2011-06-14

    IPC分类号: A61M1/36

    摘要: The present invention relates to a device and method for conveying fluids into the treatment unit of a medical treatment apparatus. The device and method according to the present invention are based on the fact that the fluid with which the treatment unit is supplied, circulates in a fluid circuit including the treatment unit. To balance fresh and used fluid fed to the treatment unit or conveyed from the treatment unit, a balancing unit with a balancing chamber is used, which can be incorporated into the fluid circuit including the treatment unit. It is thus possible to supply the fluid circuit continuously with fresh fluid or to carry away used fluid continuously from the fluid circuit. The supply and discharge of fresh and used fluid can take place at a different flow rate from the flow rate at which the fluid circulates in the fluid circuit via the treatment unit.

    摘要翻译: 本发明涉及将流体输送到医疗处理装置的处理单元中的装置和方法。 根据本发明的装置和方法基于以下事实:供应处理单元的流体在包括处理单元的流体回路中循环。 为了平衡进料到处理单元或从处理单元输送的新鲜和使用的流体,使用具有平衡室的平衡单元,其可以并入包括处理单元的流体回路中。 因此,可以连续地向新鲜流体供应流体回路,或者从流体回路连续输送用过的流体。 新鲜和使用的流体的供应和排出可以以与流体在流体回路中经由处理单元循环的流速不同的流速进行。

    Method for determining concentration; a dialyser
    6.
    发明申请
    Method for determining concentration; a dialyser 有权
    浓度测定方法 透析器

    公开(公告)号:US20050236330A1

    公开(公告)日:2005-10-27

    申请号:US11148172

    申请日:2005-06-09

    摘要: A dialyser having a haemo-dialyser and/or a haemo-filter and an extra-corporal blood circulation with which a device for the adding of citrate to the blood is connected upstream and a device for the adding of a substitution solution containing ions to the blood is connected downstream of the haemo-dialyser and/or of the haemo-filter. Ion concentration in the dialysate downstream of the haemo-dialyser and/or of the haemo-filter is detected with respect to the direction of flow of the dialysate. The concentration of the ion, atom or molecule to be determined is reliably ascertained by preventing the complexing of the ion, atom or molecule, at least during the determination of the concentration, by the addition or withdrawal of a substance.

    摘要翻译: 具有血液透析器和/或血液过滤器和体外血液循环的透析器,用于向血液中加入柠檬酸盐的装置与上游连接,以及用于将含有离子的置换溶液添加到 血液连接在血液透析器和/或血液过滤器的下游。 相对于透析液的流动方向检测透析器和/或血液滤过器下游的透析液中的离子浓度。 要确定的离子,原子或分子的浓度通过至少在浓度测定期间通过物质的添加或取出来防止离子,原子或分子的络合而被可靠地确定。

    Method for the direct diagnostic detection of genetically caused pathogenic point mutations
    7.
    发明授权
    Method for the direct diagnostic detection of genetically caused pathogenic point mutations 失效
    直接诊断检测遗传性病原点突变的方法

    公开(公告)号:US06326163B1

    公开(公告)日:2001-12-04

    申请号:US09147404

    申请日:1999-04-06

    IPC分类号: C12Q100

    摘要: The present invention relates to a quick method for the qualitative and quantitative medical-diagnostic analysis on the protein level of the substitution of single amino acids with pathogenic and non-pathogenic effects on the organism. The medical-diagnostic analysis is performed by a combination of enzymatic or chemical cleavage of the isolated peptide, chromatographical separation of the fragments and analysis by mass spectrometry, both direct LC/MS and indirect MALDI-MS, and analysis by capillary electrophoresis. By comparing protein samples from healthy humans with those of ill humans, the method described is suitable for establishing new, as yet unknown mutations and quantifying the expression and incorporation of wild type to mutant.

    摘要翻译: 本发明涉及一种用于对单个氨基酸取代的蛋白质水平进行定性和定量医学诊断分析的快速方法,其对生物具有致病和非致病作用。 医学诊断分析通过分离的肽的酶或化学切割,片段的色谱分离和质谱分析,直接LC / MS和间接MALDI-MS的分析以及毛细管电泳分析来进行。 通过比较来自健康人类的蛋白质样品与不良人类的蛋白质样品,所述方法适用于建立新的尚未知的突变并定量野生型与突变体的表达和结合。