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公开(公告)号：US20120310330A1
公开(公告)日：2012-12-06
申请号：US13397545
申请日：2012-02-15
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61B17/0469 , A61B17/8855 , A61B2017/0474 , A61B2018/0025 , A61F2/2433 , A61F2/2442 , A61F2/2445 , A61F2/2448 , A61F2/95 , A61F2/958 , A61F2/962 , A61F2210/0014 , A61F2210/0023 , A61F2210/0033 , A61F2210/0066 , A61F2220/0016 , A61F2220/0025 , A61F2220/0075 , A61F2230/0006 , A61F2230/0008 , A61M25/1011
摘要： Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves via a trans-apical approach to accessing the heart. A guiding sheath may be introduced into a ventricle of the heart through an access site at an apex of the heart. A distal end of the guiding sheath can be positioned retrograde through the target valve. An annuloplasty ring arranged in a compressed delivery geometry is advanced through the guiding sheath and into a distal portion of the guiding sheath positioned within the atrium of the heart. The distal end of the guiding sheath is retracted, thereby exposing the annuloplasty ring. The annuloplasty ring may be expanded from the delivery geometry to an operable geometry. Anchors on the annuloplasty ring may be deployed to press into and engage tissue of the annulus of the target valve.
摘要翻译： 提供了装置，系统和方法，用于通过经皮经导管递送修复心脏瓣膜，并通过穿过心脏的方式将瓣膜成形术环固定在心脏瓣膜上。 引导鞘可以通过心脏顶点的进入部位引入心脏的心室。 引导护套的远端可以通过目标阀逆行定位。 以压缩的输送几何形状布置的瓣环成形术环被推进穿过引导护套并进入位于心脏心房内的引导护套的远端部分。 引导护套的远端缩回，从而暴露瓣环成形术环。 瓣环成形术环可以从输送几何形状扩展到可操作的几何形状。 瓣膜成形术环上的锚点可以被部署以压入和接合目标瓣膜的环的组织。
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公开(公告)号：US20120123531A1
公开(公告)日：2012-05-17
申请号：US13198582
申请日：2011-08-04
申请人： Ross Tsukashima , Samuel M. Shaolian , Maurice Buchbinder , Brian C. Gray , Victor S. Packham , Hung H. Cao
发明人： Ross Tsukashima , Samuel M. Shaolian , Maurice Buchbinder , Brian C. Gray , Victor S. Packham , Hung H. Cao
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61F2/2442 , A61F2/2445 , A61F2/2448 , A61F2210/0014 , A61F2220/0016 , A61F2220/0033 , A61F2220/0075 , A61F2250/0004 , A61F2250/001 , A61F2250/0067 , A61F2250/0096
摘要： Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow member including a plurality of segments. Adjacent segments cooperate with one another to change the outer hollow member from an elongate insertion geometry to an annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the outer hollow member. The internal anchor member includes a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. The internal anchor member is configured to move the plurality of anchors with respect to a plurality of windows in the outer hollow member to selectively deploy the plurality of anchors through the respective windows.
摘要翻译： 提供装置，系统和方法用于通过经皮经导管递送和瓣膜成形术环固定到心脏瓣膜来修复心脏瓣膜。 瓣膜成形术环包括包括多个段的外部中空构件。 相邻的部分彼此协作以将外部空心构件从细长插入几何形状改变为环形可操作的几何形状。 瓣膜成形术环还包括至少部分地位于外部中空构件内部的内部锚定构件。 内部锚固构件包括构造成将瓣环成形术环附接到心脏瓣膜环的组织的多个锚固件。 内部锚固构件被构造成相对于外部中空构件中的多个窗口移动多个锚固件，以选择性地将多个锚定件展开通过相应的窗口。
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3.发明授权公开(公告)号：US09402721B2
公开(公告)日：2016-08-02
申请号：US13397545
申请日：2012-02-15
CPC分类号： A61F2/2466 , A61B17/0469 , A61B17/8855 , A61B2017/0474 , A61B2018/0025 , A61F2/2433 , A61F2/2442 , A61F2/2445 , A61F2/2448 , A61F2/95 , A61F2/958 , A61F2/962 , A61F2210/0014 , A61F2210/0023 , A61F2210/0033 , A61F2210/0066 , A61F2220/0016 , A61F2220/0025 , A61F2220/0075 , A61F2230/0006 , A61F2230/0008 , A61M25/1011
摘要： Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves via a trans-apical approach to accessing the heart. A guiding sheath may be introduced into a ventricle of the heart through an access site at an apex of the heart. A distal end of the guiding sheath can be positioned retrograde through the target valve. An annuloplasty ring arranged in a compressed delivery geometry is advanced through the guiding sheath and into a distal portion of the guiding sheath positioned within the atrium of the heart. The distal end of the guiding sheath is retracted, thereby exposing the annuloplasty ring. The annuloplasty ring may be expanded from the delivery geometry to an operable geometry. Anchors on the annuloplasty ring may be deployed to press into and engage tissue of the annulus of the target valve.
摘要翻译： 提供了装置，系统和方法，用于通过经皮经导管递送修复心脏瓣膜，并通过穿过心脏的方式将瓣膜成形术环固定在心脏瓣膜上。 引导鞘可以通过心脏顶点的进入部位引入心脏的心室。 引导护套的远端可以通过目标阀逆行定位。 以压缩的输送几何形状布置的瓣环成形术环被推进穿过引导护套并进入位于心脏心房内的引导护套的远端部分。 引导护套的远端缩回，从而暴露瓣环成形术环。 瓣膜成形术环可以从输送几何扩展到可操作的几何形状。 瓣膜成形术环上的锚点可以被部署以压入和接合目标瓣膜的环的组织。
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公开(公告)号：US08821570B2
公开(公告)日：2014-09-02
申请号：US13386331
申请日：2010-07-20
申请人： Jeffrey P. DuMontelle , Maurice Buchbinder , Samuel M. Shaolian , Ninh H. Dang , Paul A. Molloy , Ross Tsukashima , Brian C. Gray , Daniel C. Anderson
发明人： Jeffrey P. DuMontelle , Maurice Buchbinder , Samuel M. Shaolian , Ninh H. Dang , Paul A. Molloy , Ross Tsukashima , Brian C. Gray , Daniel C. Anderson
CPC分类号： A61L27/50 , A61F2/2445 , A61F2210/0023 , A61F2210/0033 , A61F2250/001 , A61L27/507
摘要： Annuloplasty rings are employed to treat heart valve defects, such as regurgitation. Synching the heart tissue to the ring restores the valve opening to its approximate original size and operating efficiency. Adjustable annuloplasty rings allow for a proper degree of synching both during open heart surgery and over the patient's lifetime. A subcutaneous port may be coupled to an adjustable annuloplasty ring such that an external activation energy generator can be used to heat the adjustable annuloplasty ring and thereby adjust the size of the annuloplasty ring.
摘要翻译： 使用瓣环成形术来治疗心脏瓣膜缺损，例如反流。 将心脏组织同步到环将瓣膜开口恢复到其近似的原始尺寸和操作效率。 可调环形成形术环允许在心脏开放心脏手术期间和患者生命周期内均匀适应程度的同步。 皮下端口可以联接到可调节瓣环成形术环，使得外部激活能量发生器可以用于加热可调节瓣环成形术环，从而调节瓣环成形术环的尺寸。
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公开(公告)号：US08518107B2
公开(公告)日：2013-08-27
申请号：US13198582
申请日：2011-08-04
申请人： Ross Tsukashima , Samuel M. Shaolian , Maurice Buchbinder , Brian C. Gray , Victor S. Packham , Hung H. Cao
发明人： Ross Tsukashima , Samuel M. Shaolian , Maurice Buchbinder , Brian C. Gray , Victor S. Packham , Hung H. Cao
IPC分类号： A61F2/24
CPC分类号： A61F2/2466 , A61F2/2442 , A61F2/2445 , A61F2/2448 , A61F2210/0014 , A61F2220/0016 , A61F2220/0033 , A61F2220/0075 , A61F2250/0004 , A61F2250/001 , A61F2250/0067 , A61F2250/0096
摘要： Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves. An annuloplasty ring includes an outer hollow member including a plurality of segments. Adjacent segments cooperate with one another to change the outer hollow member from an elongate insertion geometry to an annular operable geometry. The annuloplasty ring also includes an internal anchor member located at least partially within the outer hollow member. The internal anchor member includes a plurality of anchors configured to attach the annuloplasty ring to tissue of a heart valve annulus. The internal anchor member is configured to move the plurality of anchors with respect to a plurality of windows in the outer hollow member to selectively deploy the plurality of anchors through the respective windows.
摘要翻译： 提供装置，系统和方法用于通过经皮经导管递送和瓣膜成形术环固定到心脏瓣膜来修复心脏瓣膜。 瓣膜成形术环包括包括多个段的外部中空构件。 相邻的部分彼此协作以将外部空心构件从细长插入几何形状改变为环形可操作的几何形状。 瓣膜成形术环还包括至少部分地位于外部中空构件内部的内部锚定构件。 内部锚固构件包括构造成将瓣环成形术环附接到心脏瓣膜环的组织的多个锚固件。 内部锚固构件被构造成相对于外部中空构件中的多个窗口移动多个锚固件，以选择性地将多个锚定件展开通过相应的窗口。
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公开(公告)号：US20120197392A1
公开(公告)日：2012-08-02
申请号：US13386331
申请日：2010-07-20
申请人： Jeffrey P. DuMontelle , Maurice Buchbinder , Samuel M. Shaolian , Ninh H. Dang , Paul A. Molloy , Ross Tsukashima , Brian C. Gray , Daniel C. Anderson
发明人： Jeffrey P. DuMontelle , Maurice Buchbinder , Samuel M. Shaolian , Ninh H. Dang , Paul A. Molloy , Ross Tsukashima , Brian C. Gray , Daniel C. Anderson
IPC分类号： A61F2/24
CPC分类号： A61L27/50 , A61F2/2445 , A61F2210/0023 , A61F2210/0033 , A61F2250/001 , A61L27/507
摘要： Annuloplasty rings are employed to treat heart valve defects, such as regurgitation. Synching the heart tissue to the ring restores the valve opening to its approximate original size and operating efficiency. Adjustable annuloplasty rings allow for a proper degree of synching both during open heart surgery and over the patient's lifetime. A subcutaneous port may be coupled to an adjustable annuloplasty ring such that an external activation energy generator can be used to heat the adjustable annuloplasty ring and thereby adjust the size of the annuloplasty ring.
摘要翻译： 使用瓣环成形术来治疗心脏瓣膜缺损，例如反流。 将心脏组织同步到环将瓣膜开口恢复到其近似的原始尺寸和操作效率。 可调环形成形术环允许在心脏开放心脏手术期间和患者生命周期内均匀适应程度的同步。 皮下端口可以联接到可调节瓣环成形术环，使得外部激活能量发生器可以用于加热可调节瓣环成形术环，从而调节瓣环成形术环的尺寸。
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公开(公告)号：US09241735B2
公开(公告)日：2016-01-26
申请号：US10728728
申请日：2003-12-05
CPC分类号： A61B17/3423 , A61B17/3415 , A61B17/3417 , A61B17/3421 , A61B17/3439 , A61B2017/0225 , A61B2017/3486 , A61M25/0662 , A61M25/0668 , A61M31/005 , A61M2025/0024 , A61M2025/0681
摘要： Disclosed is an expandable percutaneous sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion to a second, enlarged cross-sectional configuration. The sheath is maintained in the first, low cross-sectional configuration by a tubular restraint. In one application, the sheath is utilized to provide access for a diagnostic or therapeutic procedure such as percutaneous nephrostomy or urinary bladder access.
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公开(公告)号：US08211153B2
公开(公告)日：2012-07-03
申请号：US11428269
申请日：2006-06-30
IPC分类号： A61B17/88
CPC分类号： A61B17/1671 , A61B17/1615 , A61B17/1642 , A61B17/1757 , A61B17/3468 , A61B17/3472 , A61B17/7001 , A61B17/7004 , A61B17/7005 , A61B17/7011 , A61B17/7019 , A61B17/702 , A61B17/704 , A61B17/7082 , A61B17/7083 , A61B17/7086 , A61B17/7089 , A61B17/861 , A61B17/864 , A61B17/8861 , A61B17/8897 , A61B2017/90
摘要： The present invention relates generally to systems and methods for aligning and implanting orthopedic fixation or stabilization implants within the body. In one embodiment, the system includes at least two bone anchors, at least one of which is provided with a transverse portal and a locking member. In one aspect, the system also includes at least one linkage rod, for linking two or more bone anchors through their respective locking members. The linking rod may include at least one angularly adjustable joint, which may be fixed by actuating the locking member. The bone anchors and the linkage rod may be locked into place to form a spinal fusion or fixation prosthesis.
摘要翻译： 本发明总体上涉及用于在整个身体内对准和植入矫形外科固定或稳定植入物的系统和方法。 在一个实施例中，该系统包括至少两个骨锚，其中至少一个具有横向入口和锁定构件。 在一个方面，该系统还包括至少一个连杆，用于通过其相应的锁定构件连接两个或多个骨锚。 连接杆可以包括至少一个角度可调节的接头，其可以通过致动锁定构件来固定。 骨锚和连接杆可以锁定就位以形成脊柱融合或固定假体。
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公开(公告)号：US20100318181A1
公开(公告)日：2010-12-16
申请号：US12860310
申请日：2010-08-20
申请人： Samuel M. Shaolian , Frank M. Zeng
发明人： Samuel M. Shaolian , Frank M. Zeng
IPC分类号： A61F2/82
CPC分类号： A61F2/856 , A61F2/07 , A61F2/89 , A61F2/90 , A61F2/954 , A61F2002/061 , A61F2002/065 , A61F2002/075 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2220/0075 , A61F2230/0054 , A61F2250/0039
摘要： Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The prosthesis can have a plurality of radially outwardly extending barbs. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion.
摘要翻译： 公开了一种可用于治疗例如腹主动脉瘤的管状腔内血管假体。 假体包括具有管状主体支撑件和第一和第二分支支撑件的自膨胀线材支撑结构。 假体可以具有多个径向向外延伸的倒钩。 分支支撑件可以与主体铰接，以允许分支在整个运动的主要范围内从主体的轴线横向枢转。
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公开(公告)号：US07833249B2
公开(公告)日：2010-11-16
申请号：US10854097
申请日：2004-05-26
IPC分类号： A61B17/70
CPC分类号： A61B17/1697 , A61B17/1671 , A61B17/1757 , A61B17/1796 , A61B17/60 , A61B17/7002 , A61B17/7008 , A61B17/7013 , A61B17/864 , A61B2017/00557 , A61F2/4611
摘要： An implantable inflatable orthopedic device is provided. The device comprises a flexible wall, defining an interior cavity, a reinforcing element exposed to the cavity, an inflation pathway in communication with the cavity, and a valve, for closing the pathway. A delivery catheter is also provided for removably carrying the orthopedic device to the treatment site.
摘要翻译： 提供可植入式充气矫形装置。 该装置包括限定内腔的柔性壁，暴露于空腔的加强元件，与空腔连通的充气路径，以及用于封闭路径的阀。 还提供输送导管，用于将矫形装置可移除地携带到治疗部位。
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