公开(公告)号：US10426383B2

公开(公告)日：2019-10-01

申请号：US13779584

申请日：2013-02-27

Applicant: Medtronic MiniMed, Inc.

Inventor： Ting Huang ,  Ashwin K. Rao ,  Rajiv Shah ,  Qingling Yang

IPC: A61B5/145 ,  A61B5/1477

Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.

公开(公告)号：US11998330B2

公开(公告)日：2024-06-04

申请号：US17162885

申请日：2021-01-29

Applicant: Medtronic MiniMed, Inc.

Inventor： Ashwin K. Rao ,  Qingling Yang ,  Ellis Garai ,  Daniel E. Pesantez

IPC: A61B5/1486 ,  A61B5/145 ,  A61B5/00

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/7246 ,  A61B2562/125

Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

公开(公告)号：US11266332B2

公开(公告)日：2022-03-08

申请号：US16552780

申请日：2019-08-27

Applicant: Medtronic MiniMed, Inc.

Inventor： Ting Huang ,  Ashwin K. Rao ,  Rajiv Shah ,  Qingling Yang

IPC: A61B5/145 ,  A61B5/1477 ,  C25D5/18 ,  A61B5/1486 ,  C12Q1/00 ,  C25D5/00 ,  C25D3/50

Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.

公开(公告)号：US20170311858A1

公开(公告)日：2017-11-02

申请号：US15140129

申请日：2016-04-27

Applicant: Medtronic MiniMed, Inc.

Inventor： Qingling Yang ,  Robert C. Mucic

IPC: A61B5/1486 ,  A61B5/145 ,  C12Q1/00

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/14735 ,  A61B2562/125 ,  C12Q1/006 ,  G01N27/3271

Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes as well as methods for making and using such sensors. The amperometric analyte sensor apparatus comprises: a base layer; a conductive layer disposed on the base layer and comprising a working electrode; an interference rejection membrane disposed on an electroactive surface of the working electrode, wherein the interference rejection membrane comprises poly(vinyl alcohol) (PVA) polymers crosslinked by an acid crosslinker, wherein the crosslinker is a dicarboxylic acid type monomer or a polymer comprising a carboxylic acid group; and an analyte sensing layer. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

公开(公告)号：US20240158827A1

公开(公告)日：2024-05-16

申请号：US18480790

申请日：2023-10-04

Applicant: Medtronic MiniMed, Inc.

Inventor： Qingling Yang ,  Ashwin K. Rao ,  Hanieh Ghadimi

IPC: C12Q1/00

CPC classification number: C12Q1/006 ,  C12Q1/004

Abstract: Embodiments of the invention provide amperometric analyte sensors having elements selected to optimize enzymatic activities associated with such sensors including polymers functionalized with enzymatic mediators as well as methods for making and using such sensors. While embodiments of the invention can be used in a variety of contexts, typical embodiments of the invention include glucose or ketone sensors used in the management of diabetes.

公开(公告)号：US20220240823A1

公开(公告)日：2022-08-04

申请号：US17162885

申请日：2021-01-29

Applicant: Medtronic MiniMed, Inc.

Inventor： Ashwin K. Rao ,  Qingling Yang ,  Ellis Garai ,  Daniel E. Pesantez

IPC: A61B5/1486 ,  A61B5/145

Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

公开(公告)号：US20190094169A1

公开(公告)日：2019-03-28

申请号：US16200337

申请日：2018-11-26

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Rajiv Shah ,  Qingling Yang ,  Robert C. Mucic ,  Jenn-Hann Larry Wang

IPC: G01N27/327 ,  C12Q1/00

Abstract: The invention pertains to analyte sensors designed to include layered compositions that provide these sensors with enhanced functional and/or material properties including, for example, resistance to damage caused by ethylene oxide during sterilization processes. Embodiments of the invention include polyvinyl alcohol N-methyl-4(4′-formylstyryl)pyridinium (SbQ) polymer materials and methods for employing such materials during the ethylene oxide sterilization of glucose sensors.

公开(公告)号：US20140243634A1

公开(公告)日：2014-08-28

申请号：US13779584

申请日：2013-02-27

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Ting Huang ,  Ashwin K. Rao ,  Rajiv Shah ,  Qingling Yang

IPC: A61B5/145 ,  A61B5/1477

CPC classification number: A61B5/14532 ,  A61B5/1477

Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.

Abstract translation: 本文公开的本发明包括电流葡萄糖传感器，其具有由以下方式形成的电极：电沉积铂黑以产生相对平滑的三维金属结构的方式，这些结构有助于传感器的可靠性和稳定性。 本发明的实施例提供具有这种均匀电极结构的分析物传感器以及用于制造和使用这些传感器电极的方法。 本发明的多个实施方案被证明可用于由糖尿病患者佩戴的电流葡萄糖传感器。

公开(公告)号：US20240298941A1

公开(公告)日：2024-09-12

申请号：US18666596

申请日：2024-05-16

Applicant: Medtronic MiniMed, Inc.

Inventor： Ashwin K. Rao ,  Qingling Yang ,  Ellis Garai ,  Daniel E. Pesantez

IPC: A61B5/1486 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/14865 ,  A61B5/14532 ,  A61B5/7246 ,  A61B2562/125

Abstract: Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes, and associated architectures, as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

公开(公告)号：US20200060586A1

公开(公告)日：2020-02-27

申请号：US16552780

申请日：2019-08-27

Applicant: Medtronic MiniMed, Inc.

Inventor： Ting Huang ,  Ashwin K. Rao ,  Rajiv Shah ,  Qingling Yang

IPC: A61B5/145 ,  C12Q1/00 ,  A61B5/1486 ,  C25D5/18 ,  A61B5/1477

Abstract: The invention disclosed herein includes amperometric glucose sensors having electrodes formed from processes that electrodeposit platinum black in a manner that produces relatively smooth three dimensional metal architectures, ones that contribute to sensor reliability and stability. Embodiments of the invention provide analyte sensors having such uniform electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals.