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公开(公告)号:US11028368B2
公开(公告)日:2021-06-08
申请号:US14385471
申请日:2013-03-11
Applicant: Membrane Protective Technologies, Inc.
Inventor: Lisa A. Herickhoff , Patrick D. Burns , Nicole R. White , James A. Herickhoff
IPC: C12N1/04 , C12N5/09 , A01N1/02 , C12N5/04 , C12N5/073 , C12N5/0735 , C12N5/075 , C12N5/076 , C12N5/0797 , C12N5/071 , C12N5/077 , C12N5/0775
Abstract: An improved cryopreservation process and substances can involve a cellular collection (1) in a cryopreservation fluid (4) that has been conditioned or treated (7) to enhance the cryopreservation process by adding (18) energy (19) such as in the surface energy of a substance in the cryopreservation fluid (4) prior to reducing energy for that same cryopreservation media for freezing. This can offer enhanced-post-cryogenic viability of the cryopreserved structures or a more optimum cooling curve (22) for a specific cell type.
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公开(公告)号:US20180207214A1
公开(公告)日:2018-07-26
申请号:US15924961
申请日:2018-03-19
Applicant: Membrane Protective Technologies, Inc.
Inventor: Lisa A. Herickhoff , James A. Herickhoff
IPC: A61K36/185
CPC classification number: A61K36/185 , A01N1/021 , A01N1/0226 , A61K31/724 , A61K36/45 , A61K36/48 , A61K36/63 , A61K36/73 , A61K36/736 , A61K36/87 , A61P15/08
Abstract: Extracts obtained from the genus Hippophae or other plant sources or compositions produced by chemical or molecular biological techniques each having in common certain moieties in amounts effective when combined with reproductive cells to reduce the loss of function.
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公开(公告)号:US11570982B2
公开(公告)日:2023-02-07
申请号:US16339258
申请日:2017-10-04
Applicant: Membrane Protective Technologies, Inc.
Inventor: Lisa A. Herickhoff , Myles Shepherd
IPC: A01N1/02 , C12N5/073 , C12N5/0735 , C12N5/075 , C12N5/076 , A61K36/73 , A61K36/185 , A61K36/48 , A61K36/45 , A61K36/63 , A61K36/87
Abstract: Embodiments of the present invention provide plant-derived extracts as a replacement for traditional cryoprotectants used to freeze tissue and cells providing a method to decrease post-thaw damage as created by the cryoprotectant. For example, extracts from the genus Hippophae or other plant sources or compositions may be used as a cryoprotectant or may even be used to replace at least some of a traditional cryoprotectant.
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公开(公告)号:US11857588B2
公开(公告)日:2024-01-02
申请号:US15924961
申请日:2018-03-19
Applicant: Membrane Protective Technologies, Inc.
Inventor: Lisa A. Herickhoff , James A. Herickhoff
IPC: A61K36/185 , A61K36/45 , A61K36/736 , A61K36/48 , A61K36/63 , A61K36/73 , A61K36/87 , A61K31/724 , A01N1/02 , A61P15/08
CPC classification number: A61K36/185 , A01N1/02 , A61K31/724 , A61K36/45 , A61K36/48 , A61K36/63 , A61K36/73 , A61K36/736 , A61K36/87 , A61P15/08
Abstract: Extracts obtained from the genus Hippophae or other plant sources or compositions produced by chemical or molecular biological techniques each having in common certain moieties in amounts effective when combined with reproductive cells to reduce the loss of function.
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5.
公开(公告)号:US20220367064A1
公开(公告)日:2022-11-17
申请号:US17765741
申请日:2020-09-30
Inventor: Clint Schwab , Lisa A. Herickhoff , Amanda Minton , Christopher Bennett , Caleb Schull
Abstract: Embodiments of the present invention provide predictions from semen qualities (7) embryo characteristics (9), qualities (11), intracellular qualities (13), extracellular qualities (14), or the like of which a computational device prediction models automated computational transformation algorithm (3) may be applied to create a prediction model transformed data (4) perhaps to generate a prediction models completed prediction output which may be used to predict parameters (6) such as fertility-related parameters, fertility of an animal, embryo success rate, or the like.
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公开(公告)号:US11166455B2
公开(公告)日:2021-11-09
申请号:US17111030
申请日:2020-12-03
Applicant: Membrane Protective Technologies, Inc.
Inventor: Lisa A. Herickhoff , Myles J. Shepherd , Raul Gonzalez-Castro , Robert F. Anders , James A. Herickhoff
IPC: A01N1/02
Abstract: Embodiments of the present invention may provide effective processing of materials through phase transitions with a mobile phase transition device which may have a frozen storage area and a thawing area and which can be used to thaw biological materials near a recipient of the materials. A mobile phase transition device may be automated so that the thawing of materials can precisely follow thawing protocols.
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7.
公开(公告)号:US20150037783A1
公开(公告)日:2015-02-05
申请号:US14385471
申请日:2013-03-11
Applicant: Membrane Protective Technologies, Inc.
Inventor: Lisa A. Herickhoff , Patrick D. Burns , Nicole R. White , James A. Herickhoff
IPC: C12N5/09 , C12N1/04 , C12N5/0735 , C12N5/075 , C12N5/073 , C12N5/077 , C12N5/0775 , C12N5/0797 , C12N5/071 , C12N5/04 , C12N5/076
CPC classification number: C12N5/0693 , A01N1/0221 , A01N1/0278 , C12N1/04 , C12N5/04 , C12N5/0603 , C12N5/0606 , C12N5/0609 , C12N5/061 , C12N5/0623 , C12N5/0626 , C12N5/0629 , C12N5/0652 , C12N5/0661 , C12N5/0665 , C12N5/067 , C12N5/0682 , C12N5/0683 , C12N2500/36
Abstract: An improved cryopreservation process and substances can involve a cellular collection (1) in a cryopreservation fluid (4) that has been conditioned or treated (7) to enhance the cryopreservation process by adding (18) energy (19) such as in the surface energy of a substance in the cryopreservation fluid (4) prior to reducing energy for that same cryopreservation media for freezing. This can offer enhanced-post-cryogenic viability of the cryopreserved structures or a more optimum cooling curve (22) for a specific cell type.
Abstract translation: 改进的冷冻保存过程和物质可以包括在经过调理或处理的冷冻保存流体(4)中的细胞收集(1)(7)以通过加入(18)能量(19)来增强冷冻保存过程,例如在表面能 的物质在冷冻保存液体(4)中,然后还原相同的冷冻保存介质用于冷冻的能量。 这可以提供冷冻保存结构的增强的低温后存活力或针对特定细胞类型的更优化的冷却曲线(22)。
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公开(公告)号:US20220183271A1
公开(公告)日:2022-06-16
申请号:US17438830
申请日:2020-03-13
Applicant: MEMBRANE PROTECTIVE TECHNOLOGIES, INC.
Inventor: Amy Scharf , Lisa A. Herickhoff , James Herickhoff , Myles Shepherd
IPC: A01N1/02
Abstract: Embodiments of the present invention provide ways to reduce detrimental impacts to in vitro and in vivo specimens (8) from temperature depression with certain medium (9) and may include providing a protective layer (7) around a droplet (12) which may contain a medium and a specimen before subjecting to temperature depression. Other embodiments may provide treatment to a recipient environment (41) before implantation of a specimen (40) which has been subjected to a temperature depression.
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公开(公告)号:US20210161127A1
公开(公告)日:2021-06-03
申请号:US17111030
申请日:2020-12-03
Applicant: Membrane Protective Technologies, Inc.
Inventor: Lisa A. Herickhoff , Myles J. Shepherd , Raul Gonzalez-Castro , Robert F. Anders , James A. Herickhoff
IPC: A01N1/02
Abstract: Embodiments of the present invention may provide effective processing of materials through phase transitions with a mobile phase transition device which may have a frozen storage area and a thawing area and which can be used to thaw biological materials near a recipient of the materials. A mobile phase transition device may be automated so that the thawing of materials can precisely follow thawing protocols.
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