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    Imino sugar derivatives demonstrate potent antiviral activity and reduced toxicity
    3.
    发明授权
    Imino sugar derivatives demonstrate potent antiviral activity and reduced toxicity 有权
    亚氨基糖衍生物表现出强大的抗病毒活性和降低的毒性

    公开(公告)号：US09040488B2

    公开(公告)日：2015-05-26

    申请号：US13061734

    申请日：2009-09-02

    申请人： Timothy M. Block ,  Jinhong Chang ,  Xiaodong Xu

    发明人： Timothy M. Block ,  Jinhong Chang ,  Xiaodong Xu

    IPC分类号： C07D211/46 ,  A61K31/445 ,  A61K31/47 ,  A61K31/7056

    CPC分类号： A61K31/47 ,  A61K31/7056 ,  C07D211/46 ,  Y02A50/393 ,  A61K2300/00

    摘要： Imino sugars, such as deoxynojirimycin (DNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II (enzymes that process N-linked glycans in glycoprotein) and exhibit broad spectrum antiviral activities against many enveloped viruses. Previously we have reported a novel DNJ derivative, OSL-95II, with antiviral activity and reduced cytotoxicity. In order to develop imino sugars with more potent antiviral activity as well as improved toxicity profile, OSL-95II was modified by diversifying the nitrogen linked alkylated side chain. The antiviral activities were initially tested in bovine viral diarrhea virus (BVDV) infected MDBK cells, yielding several imino sugar derivatives with novel structure and superior antiviral activity and toxicity profile. Furthermore, these new compounds were shown to be active against Dengue virus (DV) and West Nile virus (WNV) infection in BHK cells where potent anti-DV activity having submicromolar EC50 values and SI of greater than 900. These compounds represent a new generation of iminio sugars and their analogues, having application in the clinical treatment of infection of DV and other members of flaviviridae.

    摘要翻译： 诸如脱氧野尻霉素（DNJ）的亚氨基糖是选择性抑制细胞α-葡萄糖苷酶I和II（在糖蛋白中加工N-连接聚糖的酶）并且对许多包膜病毒展现广谱抗病毒活性的葡萄糖类似物。 以前我们已经报道了具有抗病毒活性和降低的细胞毒性的新型DNJ衍生物OSL-95II。 为了开发具有更强的抗病毒活性和改善的毒性特征的亚氨基糖，OSL-95II通过使氮连接的烷基化侧链多样化而被修饰。 首先在牛病毒性腹泻病毒（BVDV）感染的MDBK细胞中测试抗病毒活性，产生几种具有新结构和优良抗病毒活性和毒性特征的亚氨基糖衍生物。 此外，这些新化合物被证明对BHK细胞中登革热病毒（DV）和西尼罗病毒（WNV）感染具有活性，其中具有亚微摩尔EC 50值和SI大于900的有效抗DV活性。这些化合物代表新一代 的亚氨基糖及其类似物，可用于临床治疗DV和其他黄病毒成分的感染。

    Connecting device for multifunctional box and vehicle comprising the same
    4.
    发明授权
    Connecting device for multifunctional box and vehicle comprising the same 有权
    用于多功能盒和车辆的连接装置

    公开(公告)号：US08807618B2

    公开(公告)日：2014-08-19

    申请号：US13580035

    申请日：2011-02-14

    申请人： Yishi Dou ,  Minqing Yao ,  Xiaodong Xu ,  Jinjiang Liu

    发明人： Yishi Dou ,  Minqing Yao ,  Xiaodong Xu ,  Jinjiang Liu

    IPC分类号： B60R11/02

    CPC分类号： B60R11/02 ,  B60K2350/00 ,  B60K2350/941 ,  B60K2350/945 ,  B60K2350/946 ,  B60K2350/948 ,  B60R2011/0047

    摘要： A connecting device adapted for connecting a multifunctional box with a vehicle multimedia system may be provided. The connecting device may comprise a shell for holding the multifunctional box having a first open end portion and a second end portion configured with an interface, via which the multifunctional box is electrically connected with the vehicle multimedia system in a releasable manner; a locking unit formed on at least a lateral side between the first open portion and the second end portion for releasably locking the multifunctional box; and a release unit formed on the shell to release the inserted multifunctional box when pressed. A vehicle comprising the connecting device may also be provided.

    摘要翻译： 可以提供适于将多功能盒与车载机多媒体系统连接的连接装置。 连接装置可以包括用于保持具有第一开口端部的多功能盒和配置有接口的第二端部的壳体，多功能盒通过该接口以可释放的方式与车辆多媒体系统电连接; 形成在所述第一开口部和所述第二端部之间的至少一侧的锁定单元，用于可释放地锁定所述多功能盒; 以及形成在外壳上的释放单元，以在按压时释放插入的多功能盒。 还可以提供包括连接装置的车辆。

    METHOD FOR FREQUENCY REUSE IN CELLULAR NETWORK
    5.
    发明申请
    METHOD FOR FREQUENCY REUSE IN CELLULAR NETWORK 有权
    蜂窝网络频率重用方法

    公开(公告)号：US20130308571A1

    公开(公告)日：2013-11-21

    申请号：US13896454

    申请日：2013-05-17

    申请人： Xiaofeng Tao ,  Ping Zhang ,  Xiaona Li ,  Qimei Cui ,  Xiaodong Xu ,  Yingyue Xu ,  Waheed ur Rehman

    发明人： Xiaofeng Tao ,  Ping Zhang ,  Xiaona Li ,  Qimei Cui ,  Xiaodong Xu ,  Yingyue Xu ,  Waheed ur Rehman

    IPC分类号： H04W16/02

    CPC分类号： H04W16/02 ,  H04W16/12 ,  H04W16/30

    摘要： The present invention relates to the technical field of wireless communication, and discloses a method for frequency reuse based on cellular network. The method comprises the following steps: dividing the whole cellular network into a plurality of different cell clusters, wherein each cell cluster comprises three cells, every two of them being adjacent to each other; for each cell in a cell cluster, dividing the cell into a central area and an edge area according to the coverage of the cell; dividing the whole available frequency band of the network according to the user distribution and service distribution in the cell cluster; allocating divided frequency bands to the central area and the edge area in the cell cluster respectively according to preset rule; and applying the method for frequency reuse to other cell clusters, thus achieving the frequency reuse of the whole network. With the method, the average spectrum frequency efficiency of the cellular network can be improved, and interference among cells can be effectively suppressed.

    摘要翻译： 本发明涉及无线通信的技术领域，并且公开了一种基于蜂窝网络的频率复用方法。 该方法包括以下步骤：将整个蜂窝网络划分成多个不同的小区簇，其中每个小区簇包括三个小区，每个小区彼此相邻; 对于小区簇中的每个小区，根据小区的覆盖范围将小区划分成中心区域和边缘区域; 根据用户分布和服务分布对网络的整个可用频带进行划分; 根据预设规则分别将细分簇的频带分配给小区簇中的中心区域和边缘区域; 并将频率重用方法应用于其他小区集群，从而实现整个网络的频率重用。 利用该方法，可以提高蜂窝网络的平均频谱频率效率，并且可以有效地抑制小区之间的干扰。

    CSI-RI TRANSMISSION METHOD AND DETECTION METHOD AND APPARATUSES THEREOF
    7.
    发明申请
    CSI-RI TRANSMISSION METHOD AND DETECTION METHOD AND APPARATUSES THEREOF 有权
    CSI-RI传输方法及其检测方法及装置

    公开(公告)号：US20130114560A1

    公开(公告)日：2013-05-09

    申请号：US13810207

    申请日：2011-07-04

    申请人： Jianjun Liu ,  Qixing Wang ,  Zhihua Shi ,  Chengkang Pan ,  Xiaodong Xu ,  Guangyi Liu

    发明人： Jianjun Liu ,  Qixing Wang ,  Zhihua Shi ,  Chengkang Pan ,  Xiaodong Xu ,  Guangyi Liu

    IPC分类号： H04W72/04

    CPC分类号： H04W72/042 ,  H04L1/0026 ,  H04L1/0027 ,  H04L5/0057 ,  H04W72/1273

    摘要： Disclosed in embodiments of the present invention are a CSI-RS transmission method, an inspection method and a device thereof The transmission method comprises: transmitting a CSI-RS via any downlink subframe other than a special subframe, a downlink subframe transmitting a control message, or a downlink subframe transmitting a system message. Embodiments of the present invention enable the CSI-RS to be prevented from conflicting with the control message, the system message, and a message carried by the special subframe.

    摘要翻译： 本发明的实施例中公开了一种CSI-RS传输方法，检查方法及其装置。传输方法包括：经由除特殊子帧以外的下行链路子帧，发送控制消息的下行链路子帧， 或发送系统消息的下行链路子帧。 本发明的实施例使得可以防止CSI-RS与控制消息，系统消息和特殊子帧承载的消息相冲突。

    Community antenna system in the closed loop mode and the method thereof
    8.
    发明授权
    Community antenna system in the closed loop mode and the method thereof 有权
    社区天线系统在闭环模式及其方法

    公开(公告)号：US08134504B2

    公开(公告)日：2012-03-13

    申请号：US12629003

    申请日：2009-12-01

    申请人： Xiaodong Xu ,  Guangyi Liu ,  Chunfeng Cui ,  Zhigang Yan ,  Yuhong Huang

    发明人： Xiaodong Xu ,  Guangyi Liu ,  Chunfeng Cui ,  Zhigang Yan ,  Yuhong Huang

    IPC分类号： H01Q3/01

    CPC分类号： H04B7/10 ,  H04B7/0469 ,  H04B7/0617 ,  H04B7/0626

    摘要： A community antenna system in a closed loop mode and a method thereof are provided, the system includes two groups of pre-weighting processing modules, beamforming modules and antenna arrays connected in turn. The method includes the following processes: performing the pre-weighting processing on a transmission signal respectively according to the channel information corresponding to each of two antenna arrays; determining beamforming weight vectors according to two groups of steering vectors corresponding to the two antenna arrays, and performing weighting processing on the two pre-weighting processed transmission signals respectively to form two directional beams directed to the receiving antenna of a target mobile terminal; and transmitting the two directional beams via two antenna arrays with orthogonal polarization modes respectively.

    摘要翻译： 提供了一种闭环模式的社区天线系统及其方法，该系统包括依次连接的两组预加权处理模块，波束形成模块和天线阵列。 该方法包括以下处理：根据与两个天线阵列中的每一个相对应的信道信息分别对传输信号执行预加权处理; 根据与两个天线阵列相对应的两组导向矢量来确定波束成形权重向量，并且分别对两个预加权处理的传输信号执行加权处理，以形成指向目标移动终端的接收天线的两个定向波束; 并且分别经由具有正交偏振模式的两个天线阵列发送两个定向波束。

    Method for transmitting physical downlink control channel (PDCCH) information, method for determining PDCCH search space and devices thereof
    9.
    发明授权
    Method for transmitting physical downlink control channel (PDCCH) information, method for determining PDCCH search space and devices thereof 有权
    用于发送物理下行链路控制信道（PDCCH）信息的方法，用于确定PDCCH搜索空间的方法及其装置

    公开(公告)号：US08824426B2

    公开(公告)日：2014-09-02

    申请号：US13501549

    申请日：2010-10-12

    申请人： Jun Wang ,  Xiaodong Xu

    发明人： Jun Wang ,  Xiaodong Xu

    IPC分类号： H04J3/00 ,  H04L5/00 ,  H04W48/08 ,  H04W72/04 ,  H04W24/00

    CPC分类号： H04W48/08 ,  H04L5/0007 ,  H04L5/001 ,  H04L5/0053 ,  H04W24/00 ,  H04W72/042

    摘要： A method for transmitting Physical Downlink Control Channel (PDCCH) information, a method for determining PDCCH search space and devices thereof are disclosed in the present embodiments. The method for determining PDCCH search space includes the following step: Node B (NB) determines the different search spaces corresponding to different PDCCHs according to Carrier Indicator (CI) information. By applying the technical solution provided in the embodiments of the present invention, the CI information is introduced in the search space determining process, so that different search spaces can be allocated to the cross-carrier PDCCHs of one User Equipment (UE) and the NB and UE are able to exactly determine the search spaces of PDCCHs in each downlink carrier, therefore reducing the blocking probability during PDCCH scheduling process and improving the reliability of PDCCH transmission.

    摘要翻译： 在本实施例中公开了用于发送物理下行链路控制信道（PDCCH）信息的方法，用于确定PDCCH搜索空间的方法及其装置。 确定PDCCH搜索空间的方法包括以下步骤：节点B（NB）根据载波指示符（CI）信息确定与不同PDCCH相对应的不同搜索空间。 通过应用本发明实施例提供的技术方案，在搜索空间确定过程中引入了CI信息，从而可以将不同的搜索空间分配给一个用户设备（UE）和NB的跨载波PDCCH UE能够精确地确定每个下行链路载波中的PDCCH的搜索空间，因此降低了PDCCH调度过程中的阻塞概率，提高了PDCCH传输的可靠性。

    METHOD FOR ESTABLISHING COMP COOPERATING SET IN COORDINATED MULTI-POINT COMMUNICATION
    10.
    发明申请
    METHOD FOR ESTABLISHING COMP COOPERATING SET IN COORDINATED MULTI-POINT COMMUNICATION 有权
    在协调多点通信中建立合作伙伴关系的方法

    公开(公告)号：US20130223272A1

    公开(公告)日：2013-08-29

    申请号：US13884368

    申请日：2011-10-27

    申请人： Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

    发明人： Xiaofeng Tao ,  Xiaodong Xu ,  Qimei Cui ,  Ping Zhang ,  Xin Chen ,  Hongjia Li ,  Qiang Wang ,  Jie Ni

    IPC分类号： H04W24/10

    CPC分类号： H04W24/10 ,  H04B7/024 ,  H04B7/0626 ,  H04W72/0426 ,  H04W92/20

    摘要： Disclosed is a method for establishing a CoMP cooperating set in coordinated multi-point communication, the method comprising the steps of: triggering and starting a coordinated multi-point communication process; according to channel state information of all cells in a measurement cell set measured by a UE, determining a candidate CoMP cooperating set; sending a CoMP cooperating set establishment request to eNodeBs of the cooperating cells in the determined candidate CoMP cooperating set; the eNodeBs being of the cooperating cell and receiving the CoMP cooperating set establishment request responding to the CoMP cooperating set establishment request to the eNodeB of the serving cell of the UE, and sending a CoMP cooperating set establishment response to the eNodeB of the serving cell of the UE; the eNodeB of the serving cell of the UE determining a CoMP cooperating set of the UE according to information of the CoMP cooperating set establishment response; and according to a coordinated multi-point communication mode, sharing data information and service bearer information of the UE of the CoMP cooperating set. The present invention guarantees coordinated multi-point joint transmission/reception, decreases the overhead and complexity of the communication system and furthermore reduces the time delay in the information exchange.

    摘要翻译： 公开了一种在协调多点通信中建立CoMP协作集的方法，所述方法包括以下步骤：触发并启动协调的多点通信过程; 根据由UE测量的测量小区集中的所有小区的信道状态信息，确定候选的CoMP协作组; 向确定的候选CoMP协作集中的协作小区的eNodeB发送CoMP协作组建立请求; 所述eNodeB是协作小区，并且将响应于所述CoMP协作组建立请求的所述CoMP协作组建立请求接收到所述UE的所述服务小区的eNodeB，并且向所述服务小区的eNodeB发送CoMP协作集合建立响应 UE; UE的服务小区的eNodeB根据CoMP合作组建立响应的信息确定UE的CoMP协作组; 并且根据协调的多点通信模式，共享CoMP协作组的UE的数据信息和业务承载信息。 本发明保证了协调的多点联合发送/接收，降低了通信系统的开销和复杂性，进而减少了信息交换中的时延。