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    Liquid interferon-beta formulations
    2.
    发明授权
    Liquid interferon-beta formulations 有权
    液体干扰素-β制剂

    公开(公告)号：US08337826B2

    公开(公告)日：2012-12-25

    申请号：US11102723

    申请日：2005-04-11

    申请人： Michael Tschope ,  Thomas Siklosi ,  Peter Schroeder ,  Hans Hofer

    发明人： Michael Tschope ,  Thomas Siklosi ,  Peter Schroeder ,  Hans Hofer

    IPC分类号： A61K38/21 ,  A61K38/00 ,  C07K17/00

    CPC分类号： A61K38/215

    摘要： The present invention relates to liquid formulations of human interferon-β. The formulations are characterized in that they have a buffer with a pH in the weakly acidic to neutral range of between 5 and 8, preferably between over 5.5 and 8, and that they exhibit high stability of the interferon-β in solution while retaining the molecular integrity.

    摘要翻译： 本发明涉及人类干扰素的液体制剂。 制剂的特征在于它们具有pH在5至8之间，优选在5.5至8之间的弱酸性至中性范围内的缓冲液，并且它们表现出高度稳定的干扰素-bgr; 同时保持分子完整性。

    Installation for harnessing thermal energy
    3.
    发明授权
    Installation for harnessing thermal energy 失效
    安装用于利用热能

    公开(公告)号：US4819432A

    公开(公告)日：1989-04-11

    申请号：US111788

    申请日：1987-08-21

    申请人： Christian Schneider ,  Hans P. Doetsch ,  Helmut Krauss ,  Hans Hofer

    发明人： Christian Schneider ,  Hans P. Doetsch ,  Helmut Krauss ,  Hans Hofer

    IPC分类号： F02G1/04 ,  F02G1/044 ,  F25B9/00 ,  F25B9/14 ,  F25B27/00

    CPC分类号： F02G1/04 ,  F02G1/0445 ,  F25B9/14 ,  F02G2250/18

    摘要： In an installation for harnessing thermal energy, in which in a first part of an operating cycle the working fluid is positively displaced out of a first chamber into a second chamber, in which a higher temperature prevails than in the first, and in a second part of the operating cycle working fluid is positively displaced from the second chamber back into the first chamber, wherein thermal energy is supplied to the working fluid on its passage from the first to the second chamber and removed from the working fluid on its passage from the second to the first chamber, the chambers are formed by variable-volume working chambers of piston machine units (10, 12, 14, 16) coupled with one another and operating out of phase with one another, which communicate with one another by fluid ducts (18, 20, 22, 24) in such a way that the working fluid is positively displaced out of a shrinking work chamber having a relatively high temperature through a first duct, into an expanding work chamber having a lower temperature, and at the same time, working fluid from a shrinking work chamber having a lower temperature is positively displaced through a second duct into an expanding work chamber having a higher temperature. The piston engine units each operate as an entity at a predetermined temperature level, so that problems with respect to the thermal insulation cannot arise.

    摘要翻译： PCT No.PCT / EP86 / 00777 Sec。 371日期1987年8月21日 102（e）日期1987年8月21日PCT PCT日期：1986年12月23日PCT公布。 出版物WO87 / 03932 日期1987年7月2日。在用于利用热能的装置中，其中在操作循环的第一部分中，工作流体被主动地从第一室转移到第二室中，其中较高的温度比 首先，并且在操作循环的第二部分中，工作流体从第二室向后偏移到第一室中，其中热能在其从第一室到第二室的通道上被供应到工作流体，并从工作 流体在其从第二腔室到第一腔室的通道中，腔室由活塞机械单元（10,12,14,16）的可变容积的工作室形成，所述活塞机械单元彼此耦合并且彼此不同相地运动， 彼此通过流体管道（18,20,22,24），使得工作流体通过第一管道从具有相对较高温度的收缩工作室中被正确地移出到膨胀 具有较低温度的工作室，同时来自具有较低温度的收缩工作室的工作流体通过第二管道被积极地移位到具有较高温度的膨胀工作室中。 活塞发动机单元各自作为实体处于预定的温度水平，从而不能产生关于隔热的问题。

    Method for contactless measurement of three dimensional flow velocities
    4.
    发明授权
    Method for contactless measurement of three dimensional flow velocities 失效
    三维流速非接触式测量方法

    公开(公告)号：US5610703A

    公开(公告)日：1997-03-11

    申请号：US380966

    申请日：1995-01-31

    申请人： Markus Raffel ,  Jurgen Kompenhans ,  Hans Hofer

    发明人： Markus Raffel ,  Jurgen Kompenhans ,  Hans Hofer

    IPC分类号： G01P5/18 ,  H04N5/225 ,  H04N5/30 ,  G01P3/36 ,  G01F1/712

    CPC分类号： H04N5/30 ,  G01P5/18 ,  H04N5/2254

    摘要： A digital particle image velovimetry (DPIV) method for contactless measurement of three dimensional flow velocities comprising the steps of seeding a flow with tracer particles; repeatedly illuminating a plane-like interrogation volume of the seeded flow; projecting the repeatedly illuminated interrogation volume onto at least a photo sensor in a projection direction for recording pictures of the illuminated interrogation volume; and determining the three dimensional flow velocities from the pictures of the repeatedly illuminated interrogation volume recorded by the photo sensor. The plane-like interrogation volume of the invention comprises at least two partial volumes positioned parallelly parallel to each other with regard to the projection direction. The step of repeatedly illuminating the interrogation volume comprises the step of illuminating the partial volumes in such a way that the pictures of different partial volumes are distinguishable from each other. The step of determing the three dimensional flow velocities of the flow comprises the steps of calculating a local autocorrelation function of a double exposed picture of the same partial volume, or calculating a local cross-correlation function between two separate pictures of the same partial volume, calculating a local cross-correlation function between two pictures of two different partial volumes, determining the sign of the out-of-plane component of the local flow velocities by using the location of a peak of the local cross-correlation function between the two pictures of the two different partial volumes, and determining the magnitude of the out-of-plane component of the local flow velocities by using the peak heights of peaks of both local correlation functions.

    摘要翻译： 一种用于三维流速非接触式测量的数字粒子图像测速法（DPIV）方法，包括以下步骤：用示踪粒子接种流; 重复照亮种子流的平面状询问体积; 将所述重复照明的询问音量投影到投影方向上的至少一个光传感器上，用于记录所述照明询问音量的图像; 以及根据由光传感器记录的反复照明的询问量的图片确定三维流速。 本发明的平面状询问体积包括相对于投影方向彼此平行平行地定位的至少两个部分体积。 反复照亮询问体积的步骤包括以不同部分体积的图像彼此区分的方式照亮部分体积的步骤。 确定流的三维流速的步骤包括以下步骤：计算相同部分体积的双曝光图像的局部自相关函数，或计算相同部分体积的两个单独图像之间的局部互相关函数， 计算两个不同部分体积的两个图像之间的局部互相关函数，通过使用两个图像之间的局部互相关函数的峰值的位置来确定局部流速的平面外分量的符号 并且通过使用两个局部相关函数的峰的峰值高度来确定局部流速的平面外分量的大小。

    Apparatus for the three-dimensional determination of flows
    6.
    发明授权
    Apparatus for the three-dimensional determination of flows 失效
    流量三维测定装置

    公开(公告)号：US5440144A

    公开(公告)日：1995-08-08

    申请号：US142607

    申请日：1993-10-25

    申请人： Markus Raffel ,  Jurgen Kompenhans ,  Hans Hofer

    发明人： Markus Raffel ,  Jurgen Kompenhans ,  Hans Hofer

    IPC分类号： G01P5/00 ,  G01P5/18 ,  H04N13/00 ,  G01N15/06

    CPC分类号： H04N13/0207 ,  G01P5/001 ,  G01P5/18 ,  H04N13/0253 ,  H04N13/0003 ,  H04N13/0051 ,  H04N19/597 ,  H04N2013/0081

    摘要： An apparatus for the three-dimensional determination of flows has a light source for briefly illuminating a light section (3) and a stereoscopic recording device (10). The stereoscopic recording device (10) comprises two equivalent objectives (11, 12) aligned parallel to each other as well as perpendicular to the plane (22) of the light section (3), and behind the objectives (11, 12) two optical sensor fields (15, 16) aligned parallel to the plane (22). A forward displacement device for the synchronized forward displacement of the projections of the light source (3) onto the two sensor fields (15, 16) has two revolving mirrors (13, 14) aligned parallel and rotating in synchronization about a common axis of rotation (23) as well as in synchronization with the light source, whereby the axis of rotation (23) runs parallel to an imaginary line joining the two objectives (11, 12).

    摘要翻译： 用于三维流动确定的装置具有用于短暂地照亮光部分（3）和立体声记录装置（10）的光源。 立体录像装置（10）包括两个彼此平行排列并且垂直于光部分（3）的平面（22）并且在物镜（11,12）之后的两个等效物镜（11,12），两个光学 平行于平面（22）排列的传感器区域（15,16）。 用于将光源（3）的突起同步向前移位到两个传感器区域（15,16）上的向前位移装置具有两个平行对齐的旋转反射镜（13,14），并且围绕公共旋转轴线同步旋转 （23），并且与光源同步，由此旋转轴线（23）平行于连接两个物镜（11,12）的假想线延伸。

    Single crystal emitter with heater wire embedded therein
    7.
    发明授权
    Single crystal emitter with heater wire embedded therein 失效
    单晶发射器，加热线嵌入其中

    公开(公告)号：US4843277A

    公开(公告)日：1989-06-27

    申请号：US101575

    申请日：1987-09-28

    申请人： Otto Winkler ,  Hans Hofer

    发明人： Otto Winkler ,  Hans Hofer

    IPC分类号： C30B29/10 ,  H01J1/15 ,  H01J1/20

    CPC分类号： H01J1/20

    摘要： Improved anchoring of heating elements of a resistance heater to thermally stressed single crystals is achieved by embedding the individual heating element in a recess in the single crystal and permanently joining this to the heating element by a porous sintered composition. The sintered composition is formed by the heat treatment of a suspension that in addition to other components, contains material with the same chemical composition in powdered form as that of the single crystal.

    摘要翻译： 通过将单独的加热元件嵌入在单晶体的凹槽中并通过多孔烧结组合物将其永久地连接到加热元件上来实现电阻加热器的加热元件对热应力单晶的改进的锚定。 烧结组合物通过热处理悬浮液而形成，该悬浮液除了其它组分外还含有与单晶粉末形式相同的化学成分的材料。

    Adsorbing material comprised of porous functional solid incorporated in a polymer matrix
    9.
    发明申请
    Adsorbing material comprised of porous functional solid incorporated in a polymer matrix 审中-公开
    吸收材料由多孔功能固体掺入聚合物基质中组成

    公开(公告)号：US20060105158A1

    公开(公告)日：2006-05-18

    申请号：US10500349

    申请日：2002-12-20

    申请人： Hans Fritz ,  Hans Hofer ,  Jochen Hammer

    发明人： Hans Fritz ,  Hans Hofer ,  Jochen Hammer

    IPC分类号： B32B5/22

    CPC分类号： B01J20/28026 ,  B01D53/02 ,  B01D2253/202 ,  B01J20/183 ,  B01J20/26 ,  B01J20/28042 ,  B01J20/28045 ,  B01J20/28069 ,  C02F1/42 ,  Y02C10/08 ,  Y10T428/249955 ,  Y10T428/249958 ,  Y10T428/249969 ,  Y10T428/249986

    摘要： The present invention relates to an adsorbing material which comprises at least one porous functional solid, e.g. a zeolite, incorporated in a polymer matrix. The adsorbing material contains the porous functional solid in an amount of 45 to 80 wt. %. The polymer matrix comprises at least one organic polymer, particularly selected from thermoplastics, and has a secondary pore volume in addition to the primary pore volume of the porous functional solid. Further, the present invention is directed to a shaped article, which comprises or consists of the afore-mentioned adsorbing material, to a method for its preparation and to its use. The present invention is finally conerned with the use of specific rheological additives, in particular waxy components, which function as pore-forming agents in the preparation of shaped articles.

    摘要翻译： 本发明涉及一种吸附材料，其包含至少一种多孔功能固体，例如， 掺入聚合物基质中的沸石。 吸附材料含有45〜80重量％的多孔功能性固体。 ％。 聚合物基质包含至少一种有机聚合物，特别是选自热塑性塑料，除了多孔功能固体的主孔体积之外，还具有二次孔体积。 此外，本发明涉及一种成形制品，其包含或由上述吸附材料组成，涉及其制备方法及其用途。 本发明最终结合使用特定的流变添加剂，特别是在成型制品的制备中用作成孔剂的蜡质组分。

    Bimetal multiple cylinder for extruders in plastics processing machinery
    10.
    发明授权
    Bimetal multiple cylinder for extruders in plastics processing machinery 失效
    双金属多缸挤出机在塑料加工机械

    公开(公告)号：US3970113A

    公开(公告)日：1976-07-20

    申请号：US473896

    申请日：1974-05-28

    申请人： Urs Guttinger ,  Hans Hofer

    发明人： Urs Guttinger ,  Hans Hofer

    IPC分类号： F16J10/00 ,  B29B7/00 ,  B29C47/00 ,  B29C47/08 ,  B29C47/40 ,  B29C47/66 ,  F04C2/08 ,  F16L9/00 ,  F16L9/02 ,  F16L9/22 ,  B29B1/04 ,  B29F3/02

    CPC分类号： B29C47/0847 ,  F04C2/086 ,  F16L9/006 ,  F16L9/02 ,  B29C47/0009

    摘要： A bimetal multiple cylinder for extruders in plastics processing machinery is formed of a plurality of cut-away bimetal tubes having each a base material supporting an internal lining. The bimetal tubes are each cut-away by a pair of longitudinal cuts extending from the tube exterior to the tube interior to expose a pair of cut faces, and the cut faces are each arranged to face a respective cut face of an adjacent cut-away bimetal tube. Adjacent cut-away bimetal tubes are joined to one another by welding at their facing cut faces.

    摘要翻译： 用于塑料加工机械的挤出机的双金属多缸由多个切割的双金属管形成，每个双金属管具有支撑内衬的基材。 双金属管各自被从管外部延伸到管内部的一对纵向切口切割，以暴露一对切割面，并且切割面各自布置成面向相邻切口的相应切割面 双金属管。 相邻的切割双金属管通过在其相对的切割面处焊接而相互连接。