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公开(公告)号：US06371675B1
公开(公告)日：2002-04-16
申请号：US09741562
申请日：2000-12-20
IPC分类号： A61M3500
CPC分类号： A45D34/04 , A45D2200/1018 , A61M35/006 , B65D47/44
摘要： The applicator for an anti-microbial prep solution of this invention includes a generally hollow handle having a closed proximal end and an open distal end, a foam pad attached to the hollow handle over the open distal end, and a slit formed in the foam pad that acts as a flow control valve.
摘要翻译： 用于本发明的抗微生物制剂溶液的施用器包括具有闭合的近端和开放的远端的通常中空的手柄，在敞开的远端附接到中空手柄的泡沫垫，以及形成在泡沫垫中的狭缝 作为流量控制阀。
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公开(公告)号：US5439681A
公开(公告)日：1995-08-08
申请号：US72658
申请日：1993-06-07
申请人： Mohammad A. Khan , Minh Q. Hoang
发明人： Mohammad A. Khan , Minh Q. Hoang
IPC分类号： A01N25/02 , A01N25/30 , A01N31/08 , A61L2/18 , C11D1/22 , C11D1/29 , C11D1/34 , C11D1/72 , C11D1/83 , C11D3/48 , A61K9/08
摘要： A unique antimicrobial composition comprising parachlorometaxylenol, nonionic surfactant, anionic surfactant, foam builder, moisturizer and/or emollient thickener and an acid to adjust to pH. The composition is useful in providing antimicrobial effectiveness in surgical scrub applications with mildness characteristics.
摘要翻译： 一种独特的抗微生物组合物，其包含对氯甲ax yl酚，非离子表面活性剂，阴离子表面活性剂，泡沫助洗剂，保湿剂和/或润肤剂增稠剂和酸以调节至pH。 该组合物可用于在具有温和特性的手术擦洗应用中提供抗微生物效果。
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公开(公告)号：US20110150958A1
公开(公告)日：2011-06-23
申请号：US12877519
申请日：2010-09-08
CPC分类号： A61K31/045 , A01N25/34 , A01N31/02 , A01N47/44 , A61K8/34 , A61K8/43 , A61K31/155 , A61K2800/592 , A61L2/0088 , A61L2/18 , A61L2/22 , A61L2/235 , A61L2/238 , A61Q17/00 , A01N25/10 , A01N31/16 , A01N2300/00 , A61K2300/00
摘要： An antiseptic cleaning agent, generally, comprising chlorhexidine acetate and a solvent, such as an alcohol and/or water. The chlorhexidine acetate acts as a highly effective biocide. Additionally, the chlorhexidine acetate allows the cleaning agent to dry without leaving a tacky residue. Where the cleaning agent comprises one or more alcohols, the alcohols may comprise any suitable alcohols, including lower alcohols having from 1 to 6 carbon atoms, such as ethanol and isopropanol. Where the ratio of ethanol to isopropanol may be from between about 1:1000 to about 1000:1. In addition to chlorhexidine acetate, the cleaning agent optionally comprises another non-alcohol biocide, such as triclosan. The cleaning agent can be used in any suitable manner. For instance, the cleaning agent may be impregnated in an absorbent material, such as a towelette, swabstick, or gauze. Additionally, the absorbent material may comprise a positively charged or a non-ionic substance, such as polypropylene or polyester.
摘要翻译： 一种防腐清洁剂，通常包括乙酸氯己定和溶剂如醇和/或水。 醋酸氯己定作为高效杀菌剂。 此外，乙酸氯己定允许清洁剂干燥而不留下粘性残留物。 当清洁剂包含一种或多种醇时，醇可以包括任何合适的醇，包括具有1至6个碳原子的低级醇，例如乙醇和异丙醇。 其中乙醇与异丙醇的比例可以在约1:1000至约1000:1之间。 除了乙酸氯己定之外，清洁剂任选地包含另一种非醇类杀生物剂，例如三氯生。 清洁剂可以任何合适的方式使用。 例如，清洁剂可以浸渍在吸收材料中，例如毛巾，拭子或纱布。 此外，吸收材料可以包括带正电荷或非离子物质，例如聚丙烯或聚酯。
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公开(公告)号：US5547662A
公开(公告)日：1996-08-20
申请号：US113445
申请日：1993-08-27
申请人： Mohammad A. Khan , Minh Q. Hoang
发明人： Mohammad A. Khan , Minh Q. Hoang
IPC分类号： A61K9/70 , A61K31/155 , A61K31/44 , A61K33/18 , A61K45/00 , A61K47/06 , A61K47/08 , A61K47/10 , A61K47/14 , A61L26/00 , A61P17/00 , A41D13/10 , A41D19/00
CPC分类号： A61L26/0066 , A61K9/7015 , A61L26/0014 , A61L26/0023 , A61L2300/404 , A61L2300/442
摘要： A film forming composition for preparation of a skin surface as a surgical site includes a film forming material and a antimicrobial agent soluble in a fugitive solvent. The composition when applied to the skin surface forms a substantially water insoluble, substantially tack-free flexible film adherent to the skin surface. The film is capable of releasably retaining the antimicrobial agent to substantially inhibit microbial growth on the skin surface. The film releases sufficient antimicrobial agent to substantially eliminate the microorganisms normally present on the skin surface to prepare the surface for the procedure and continues to release the antimicrobial agent during the procedure and subsequent wound healing. A preferred embodiment of the composition includes at least one compound for providing a first color indicative of the skin surface area covered by the composition and develops a second color upon the substantial elimination of the fugitive solvent indicating that the site is ready. A method for use of the composition to prepare a skin surface for a surgical procedure includes providing the composition, observing the first color for indicating the skin area covered and the second color indicating that the fugitive solvent has substantially evaporated. A single use kit for preparing a skin surface for a surgical procedure includes a non-resealable unit container of the film forming composition and an applicator in a non-resealable package.
摘要翻译： 用于制备作为外科手术部位的皮肤表面的成膜组合物包括成膜材料和可溶于挥发性溶剂的抗微生物剂。 当施用于皮肤表面时的组合物形成粘附于皮肤表面的基本上不溶于水的，基本上无粘性的柔性膜。 该膜能够可释放地保持抗微生物剂以基本上抑制皮肤表面上的微生物生长。 该膜释放足够的抗微生物剂以基本上消除通常存在于皮肤表面上的微生物以制备该方法的表面，并在手术和随后的伤口愈合期间继续释放抗微生物剂。 该组合物的优选实施方案包括至少一种化合物，用于提供指示由组合物覆盖的皮肤表面积的第一颜色，并且在基本上消除指示该部位准备就绪的挥发性溶剂之后产生第二种颜色。 使用该组合物来制备用于外科手术的皮肤表面的方法包括提供该组合物，观察第一种颜色以指示被覆盖的皮肤区域，以及第二种颜色，指示该挥发性溶剂基本蒸发。 用于制备用于外科手术的皮肤表面的单一用途试剂盒包括成膜组合物的不可重新密封的单位容器和不可重新密封的包装中的施用器。
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公开(公告)号：US5607699A
公开(公告)日：1997-03-04
申请号：US440288
申请日：1995-05-12
申请人： Minh Q. Hoang , Mohammad A. Khan
发明人： Minh Q. Hoang , Mohammad A. Khan
IPC分类号： A61K8/00 , A01N59/12 , A61K8/02 , A61K8/20 , A61K8/31 , A61K8/34 , A61K8/39 , A61K8/46 , A61K8/86 , A61K8/87 , A61K8/92 , A61K8/97 , A61K31/00 , A61K33/18 , A61P17/00 , A61Q17/00 , A61Q19/10 , A61K33/36 , A61K31/355
CPC分类号： A61Q17/005 , A01N59/12 , A61K33/18 , A61K8/02 , A61K8/20 , A61K8/31 , A61K8/39 , A61K8/463 , A61K8/86 , A61K8/90 , A61K8/922 , A61K8/97 , A61Q19/10 , A61K2800/31
摘要： Non-aqueous emollient iodophor formulations for use as a skin washing agents, comprising non-ionic surfactants, coconut oil, mineral oil, iodine, sodium iodide and an organic base solvent. The non-aqueous formulations substantially do not irritate the skin and will provide antimicrobial effectiveness to the skin.
摘要翻译： 用作皮肤洗涤剂的非水性柔软剂碘伏剂制剂，包括非离子表面活性剂，椰子油，矿物油，碘，碘化钠和有机碱性溶剂。 非水性制剂基本上不刺激皮肤，并且将为皮肤提供抗微生物效能。
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公开(公告)号：US5334388A
公开(公告)日：1994-08-02
申请号：US122829
申请日：1993-09-15
申请人： Minh Q. Hoang , Mohammed A. Khan
发明人： Minh Q. Hoang , Mohammed A. Khan
IPC分类号： A01N25/34
CPC分类号： A01N25/34
摘要： A dry towel or wipe comprising an absorbent paper substrate which is uniformly coated and dried with an antimicrobial formulation comprising a volatile liquid, an active antimicrobial agent, a water soluble polymer, a polyalkylene glycol an emollient and water. The treated towel is useful in providing antimicrobial effectiveness for drying skin in preparation for surgical procedures without irritating or drying the skin.
摘要翻译： 一种干毛巾或擦拭物，其包括用包含挥发性液体，活性抗微生物剂，水溶性聚合物，聚亚烷基二醇，软化剂和水的抗微生物制剂均匀地包衣和干燥的吸收纸基材。 经处理的毛巾可用于提供用于干燥皮肤的抗微生物效果以准备外科手术而不刺激或干燥皮肤。
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公开(公告)号：US5180061A
公开(公告)日：1993-01-19
申请号：US756661
申请日：1991-09-09
申请人： Mohammad A. Khan , Minh Q. Hoang
发明人： Mohammad A. Khan , Minh Q. Hoang
IPC分类号： A61B19/08 , A01N25/10 , A01N59/12 , A61B19/00 , A61L2/16 , A61L15/18 , A61L15/26 , C11D3/48 , C11D17/04
摘要： A surgical scrub includes a polyurethane foam sponge impregnated with a composition which includes iodine, iodide and a nonionic surfactant in a polar vehicle. The scrub may be attached to a plastic handle and may be supplied along with other optional scrubbing items in a package wrapped in plastic film.
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公开(公告)号：US07704935B1
公开(公告)日：2010-04-27
申请号：US12349347
申请日：2009-01-06
CPC分类号： A61K31/045 , A01N31/02 , A01N47/44 , A61K8/43 , A61K31/155 , A61K31/70 , A61K45/06 , A61L2/0088 , A61L2202/24 , A61Q17/005 , A61Q19/00 , C11D3/48 , C11D7/261 , C11D7/3272 , C11D7/5022 , C11D17/049 , A01N31/08 , A01N2300/00 , A61K2300/00
摘要： An antiseptic cleaning agent, generally, comprising chlorhexidine acetate and a solvent, such as an alcohol and/or water. The chlorhexidine acetate acts as a highly effective biocide. Additionally, the chlorhexidine acetate allows the cleaning agent to dry without leaving a tacky residue. Where the cleaning agent comprises one or more alcohols, the alcohols may comprise any suitable alcohols, including lower alcohols having from 1 to 6 carbon atoms, such as ethanol and isopropanol. In addition to chlorhexidine acetate, the cleaning agent optionally comprises another non-alcohol biocide, such as triclosan. The cleaning agent can be used in any suitable manner. For instance, the cleaning agent may be impregnated in an absorbent material, such as a towelette, swabstick, or gauze. Additionally, the absorbent material may comprise a positively charged or a non-ionic substance, such as polypropylene or polyester.
摘要翻译： 一种防腐清洁剂，通常包括乙酸氯己定和溶剂如醇和/或水。 醋酸氯己定作为高效杀菌剂。 此外，乙酸氯己定允许清洁剂干燥而不留下粘性残留物。 当清洁剂包含一种或多种醇时，醇可以包括任何合适的醇，包括具有1至6个碳原子的低级醇，例如乙醇和异丙醇。 除了乙酸氯己定之外，清洁剂任选地包含另一种非醇类杀生物剂，例如三氯生。 清洁剂可以任何合适的方式使用。 例如，清洁剂可以浸渍在吸收材料中，例如毛巾，拭子或纱布。 此外，吸收材料可以包括带正电荷或非离子物质，例如聚丙烯或聚酯。
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公开(公告)号：US5922314A
公开(公告)日：1999-07-13
申请号：US926959
申请日：1997-09-10
申请人： Minh Q. Hoang , Mohammad A. Khan
发明人： Minh Q. Hoang , Mohammad A. Khan
CPC分类号： A01N59/12
摘要： An antimicrobial film-forming composition which provides antimicrobial effectiveness to the skin, comprising ethyl alcohol, carboxylated polyacrylates, a cross linking agent, an adhesion promoting agent which can include a secondary solvent and an emollient, an active antimicrobial agent which can be either iodine or povidone iodine, a pluronic polyol and optionally, water. This composition prevents degradation of iodine in the composition and is easily removable from the skin.
摘要翻译： 一种抗微生物成膜组合物，其对皮肤提供抗微生物效能，包括乙醇，羧化聚丙烯酸酯，交联剂，可包含第二溶剂和软化剂的粘附促进剂，可以是碘或 聚维酮碘，普朗尼克多元醇和任选的水。 该组合物可防止组合物中碘的降解，并且容易从皮肤上除去。
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公开(公告)号：US5763412A
公开(公告)日：1998-06-09
申请号：US823948
申请日：1997-04-08
申请人： Mohammad A. Khan , Minh Q. Hoang
发明人： Mohammad A. Khan , Minh Q. Hoang
CPC分类号： A01N47/44 , A61L26/0023
摘要： An antimicrobial film forming surgical site preparation composition includes a film forming material and an antimicrobial agent soluble in a fugitive solvent. The composition when applied to the skin surface forms a substantially water insoluble, substantially tack-free flexible film adherent to the skin surface. The film is capable of releasably retaining the antimicrobial agent to substantially inhibit microbial growth on the skin surface. The film releases sufficient antimicrobial agent to substantially eliminate the microorganisms normally present on the skin surface to prepare the surface for the procedure and continues to release the antimicrobial agent during the procedure and subsequent wound healing. The composition can be easily washed from fabric and does not stain the fabric even where the fabric is treated with chlorine bleach. In addition, a smooth continuous film is formed without the use of a separate plasticizer.
摘要翻译： 抗微生物膜形成手术部位制备组合物包括成膜材料和可溶于挥发性溶剂的抗微生物剂。 当施用于皮肤表面时的组合物形成粘附于皮肤表面的基本上不溶于水的，基本上无粘性的柔性膜。 该膜能够可释放地保持抗微生物剂以基本上抑制皮肤表面上的微生物生长。 该膜释放足够的抗微生物剂以基本上消除通常存在于皮肤表面上的微生物以制备该方法的表面，并在手术和随后的伤口愈合期间继续释放抗微生物剂。 组合物可以容易地从织物洗涤，并且即使织物用氯漂白剂处理也不会污染织物。 此外，形成光滑的连续膜，而不使用单独的增塑剂。
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