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1.发明申请PROCESSES, ARRANGEMENTS AND SYSTEMS FOR PROVIDING A FIBER LAYER THICKNESS MAP BASED ON OPTICAL COHERENCE TOMOGRAPHY IMAGES 有权基于光学相干图像图像提供光纤层厚度图的方法，布置和系统公开(公告)号：US20070263227A1
公开(公告)日：2007-11-15
申请号：US11744412
申请日：2007-05-04
申请人： Mircea Mujat , Raymond Chan , Johannes De Boer
发明人： Mircea Mujat , Raymond Chan , Johannes De Boer
IPC分类号： G01B11/02
CPC分类号： A61B3/102 , G06T7/12 , G06T7/149 , G06T2207/10101 , G06T2207/20116 , G06T2207/30041
摘要： A system, arrangement, computer-accessible medium and process are provided for determining information associated with at least one portion of an anatomical structure. For example, an interference between at least one first radiation associated with a radiation directed to the anatomical structure and at least one second radiation associated with a radiation directed to a reference can be detected. Three-dimensional volumetric data can be generated for the at least one portion as a function of the interference. Further, the information can be determined which is at least one geometrical characteristic and/or at least one intensity characteristic of the portion based on the volumetric data.
摘要翻译： 提供了一种用于确定与解剖结构的至少一部分相关联的信息的系统，布置，计算机可访问介质和过程。 例如，可以检测到与指向解剖结构的辐射相关联的至少一个第一辐射与定向到参考的辐射相关联的至少一个第二辐射之间的干扰。 作为干扰的函数，可以针对至少一个部分生成三维体积数据。 此外，可以基于体积数据来确定哪个是该部分的至少一个几何特征和/或至少一个强度特性。
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公开(公告)号：US08911144B2
公开(公告)日：2014-12-16
申请号：US13454720
申请日：2012-04-24
申请人： Mircea Mujat , William J. Kessler
发明人： Mircea Mujat , William J. Kessler
CPC分类号： G01N25/12 , G01B9/02091 , G01B11/24 , G01N21/4795
摘要： A product critical temperature during freeze drying is determined. The product is imaged using optical coherence tomography (“OCT”). The product is freeze dried while the temperature of the product is measured. The product critical temperature is the temperature at which a product structure event occurs during freeze drying.
摘要翻译： 确定冷冻干燥期间的产品临界温度。 使用光学相干断层扫描（“OCT”）对产品进行成像。 产品在测量产品的温度时冷冻干燥。 产品临界温度是冷冻干燥期间产品结构事件发生的温度。
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公开(公告)号：US08696122B2
公开(公告)日：2014-04-15
申请号：US13011404
申请日：2011-01-21
申请人： Daniel X. Hammer , R. Daniel Ferguson , Mircea Mujat , Anket H. Patel , Nicusor V. Iftimia , Stephen Burns
发明人： Daniel X. Hammer , R. Daniel Ferguson , Mircea Mujat , Anket H. Patel , Nicusor V. Iftimia , Stephen Burns
CPC分类号： A61B3/1015 , A61B3/102 , A61B3/1025 , A61B3/1225 , A61B3/14
摘要： An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image.
摘要翻译： 光学装置包括能够以扫描激光检眼镜（SLO）模式和光学相干断层摄影（OCT）模式操作的光学部件的系统。 光学部件的系统包括用于SLO模式的第一光学模块，用于OCT模式的第二光学模块和第一扫描装置。 用于SLO模式的第一光学模块包括适于为SLO模式提供第一成像光束的第一光源和被配置为接收与眼睛的视网膜的第一图像相关联的第一信号的第一检测装置。 用于OCT模式的第二光学模块包括适于为OCT模式提供第二成像光束的第二光源和被配置为接收与视网膜的第二图像相关联的第二信号的第二检测装置。 第一扫描装置被配置成沿着SLO模式的慢轴沿着视网膜移动第一成像光束以获取第一图像，并且（ii）将第二成像光束沿着OCT模式的快轴中的视网膜移动到 获取第二个图像。
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公开(公告)号：US20130229620A1
公开(公告)日：2013-09-05
申请号：US13411826
申请日：2012-03-05
IPC分类号： A61B3/14
CPC分类号： A61B3/1025
摘要： A retinal imaging device includes an optical system configured to (i) scan a portion of the retina of the eye with a line of light, (ii) descan reflected light from the scanned portion of the retina, and (iii) provide output light in a line focus configuration. The device includes a detection device including a linear array of asymmetric pixels having at least a 2:1 ratio of length to width, a detection device with multiple adjacent linear arrays, and/or a detection device using a time delay and integration (TDI) architecture.
摘要翻译： 视网膜成像装置包括光学系统，其被配置为（i）用一条光线扫描眼睛的视网膜的一部分，（ii）从所述视网膜的被扫描部分引出的反射光，以及（iii） 线对焦配置。 该装置包括检测装置，该检测装置包括具有至少2比1长度与宽度的不对称像素的线性阵列，具有多个相邻线性阵列的检测装置和/或使用时间延迟和积分（TDI）的检测装置， 建筑。
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公开(公告)号：US20100195048A1
公开(公告)日：2010-08-05
申请号：US12688217
申请日：2010-01-15
IPC分类号： A61B3/14
CPC分类号： A61B3/1025
摘要： A first optical module scans a portion of an eye with a line of light, descans reflected light from the scanned portion of the eye and confocally provides output light in a line focus configuration. A detection device detects the output light and images the portion of the eye. A second optical module detects an optical distortion and corrects the optical distortion in the line of light scanned on the portion of the eye.
摘要翻译： 第一光学模块用一条光线扫描眼睛的一部分，从而扫描来自眼睛的扫描部分的反射光，并且以线对焦配置共同提供输出光。 检测装置检测输出光并对眼睛的部分进行成像。 第二光学模块检测光学失真并校正在眼睛部分上扫描的光线中的光学失真。
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公开(公告)号：US20120294328A1
公开(公告)日：2012-11-22
申请号：US13454720
申请日：2012-04-24
申请人： Mircea Mujat , William J. Kessler
发明人： Mircea Mujat , William J. Kessler
CPC分类号： G01N25/12 , G01B9/02091 , G01B11/24 , G01N21/4795
摘要： A product critical temperature during freeze drying is determined. The product is imaged using optical coherence tomography (“OCT”). The product is freeze dried while the temperature of the product is measured. The product critical temperature is the temperature at which a product structure event occurs during freeze drying.
摘要翻译： 确定冷冻干燥期间的产品临界温度。 使用光学相干断层扫描（OCT）对产品进行成像。 产品在测量产品的温度时冷冻干燥。 产品临界温度是冷冻干燥期间产品结构事件发生的温度。
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公开(公告)号：US08201943B2
公开(公告)日：2012-06-19
申请号：US12688217
申请日：2010-01-15
CPC分类号： A61B3/1025
摘要： A first optical module scans a portion of an eye with a line of light, descans reflected light from the scanned portion of the eye and confocally provides output light in a line focus configuration. A detection device detects the output light and images the portion of the eye. A second optical module detects an optical distortion and corrects the optical distortion in the line of light scanned on the portion of the eye.
摘要翻译： 第一光学模块用一条光线扫描眼睛的一部分，从而扫描来自眼睛的扫描部分的反射光，并且以线对焦配置共同提供输出光。 检测装置检测输出光并对眼睛的部分进行成像。 第二光学模块检测光学失真并校正在眼睛部分上扫描的光线中的光学失真。
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公开(公告)号：US20120101390A1
公开(公告)日：2012-04-26
申请号：US13277481
申请日：2011-10-20
CPC分类号： A61K49/0093 , A61B5/0035 , A61B5/0066 , A61B5/0071 , A61B5/0084 , A61B2560/0406 , A61K49/0056 , A61K49/0091 , B82Y5/00 , B82Y30/00
摘要： Epithelial cancer screening can include a staining tissue with a cancer targeting agent, identifying a potentially cancerous lesion using fluorescence imaging, and imaging the potentially cancerous lesion for a cancer diagnosis using optical coherence tomography.
摘要翻译： 上皮癌筛选可以包括具有癌症靶向剂的染色组织，使用荧光成像识别潜在的癌性病变，并使用光学相干断层扫描来成像癌症诊断的潜在癌性病变。
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公开(公告)号：US20110234978A1
公开(公告)日：2011-09-29
申请号：US13011404
申请日：2011-01-21
申请人： Daniel X. Hammer , R. Daniel Ferguson , Mircea Mujat , Anket H. Patel , Nicusor V. Iftimia , Stephen Burns
发明人： Daniel X. Hammer , R. Daniel Ferguson , Mircea Mujat , Anket H. Patel , Nicusor V. Iftimia , Stephen Burns
CPC分类号： A61B3/1015 , A61B3/102 , A61B3/1025 , A61B3/1225 , A61B3/14
摘要： An optical apparatus includes a system of optical components capable of operating in a scanning laser ophthalmoscope (SLO) mode and an optical coherence tomography (OCT) mode. The system of optical components includes a first optical module for the SLO mode, a second optical module for the OCT mode, and a first scanning device. The first optical module for the SLO mode includes a first source adapted to provide a first imaging beam for the SLO mode and a first detection device configured to receive a first signal associated with a first image of a retina of an eye. The second optical module for the OCT mode includes a second source adapted to provide a second imaging beam for the OCT mode and a second detection device configured to receive a second signal associated with a second image of the retina. The first scanning device is configured to move the first imaging beam along the retina in the slow axis of the SLO mode to acquire the first image and (ii) to move the second imaging beam along the retina in the fast axis of the OCT mode to acquire the second image.
摘要翻译： 光学装置包括能够以扫描激光检眼镜（SLO）模式和光学相干断层摄影（OCT）模式操作的光学部件的系统。 光学部件的系统包括用于SLO模式的第一光学模块，用于OCT模式的第二光学模块和第一扫描装置。 用于SLO模式的第一光学模块包括适于为SLO模式提供第一成像光束的第一光源和被配置为接收与眼睛的视网膜的第一图像相关联的第一信号的第一检测装置。 用于OCT模式的第二光学模块包括适于为OCT模式提供第二成像光束的第二光源和被配置为接收与视网膜的第二图像相关联的第二信号的第二检测装置。 第一扫描装置被配置成沿着SLO模式的慢轴沿着视网膜移动第一成像光束以获取第一图像，并且（ii）将第二成像光束沿着OCT模式的快轴中的视网膜移动到 获取第二个图像。
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10.发明授权Processes, arrangements and systems for providing a fiber layer thickness map based on optical coherence tomography images 有权基于光学相干断层图像提供纤维层厚度图的方法，布置和系统公开(公告)号：US07782464B2
公开(公告)日：2010-08-24
申请号：US11744412
申请日：2007-05-04
IPC分类号： G01B9/02
CPC分类号： A61B3/102 , G06T7/12 , G06T7/149 , G06T2207/10101 , G06T2207/20116 , G06T2207/30041
摘要： A system, arrangement, computer-accessible medium and process are provided for determining information associated with at least one portion of an anatomical structure. For example, an interference between at least one first radiation associated with a radiation directed to the anatomical structure and at least one second radiation associated with a radiation directed to a reference can be detected. Three-dimensional volumetric data can be generated for the at least one portion as a function of the interference. Further, the information can be determined which is at least one geometrical characteristic and/or at least one intensity characteristic of the portion based on the volumetric data.
摘要翻译： 提供了一种用于确定与解剖结构的至少一部分相关联的信息的系统，布置，计算机可访问介质和过程。 例如，可以检测到与指向解剖结构的辐射相关联的至少一个第一辐射与定向到参考的辐射相关联的至少一个第二辐射之间的干扰。 作为干扰的函数，可以针对至少一个部分生成三维体积数据。 此外，可以基于体积数据来确定哪个是该部分的至少一个几何特征和/或至少一个强度特性。
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