公开(公告)号：US20240318132A1

公开(公告)日：2024-09-26

申请号：US18733979

申请日：2024-06-05

申请人： Miyaka Ogihara ,  Natsuko Hemmi ,  Naoki Satoh ,  Hidekazu Yaginuma ,  Masayuki Yumoto ,  Toshihiko Hosoya

发明人： Miyaka Ogihara ,  Natsuko Hemmi ,  Naoki Satoh ,  Hidekazu Yaginuma ,  Masayuki Yumoto ,  Toshihiko Hosoya

IPC分类号： C12N5/00 ,  B33Y70/10 ,  C08J3/075 ,  C12N5/0793

CPC分类号： C12N5/0062 ,  B33Y70/10 ,  C08J3/075 ,  C12N5/0619 ,  C08J2389/00

摘要： An object of the present invention is to provide a hydrogel that has both gel shapeability and cell adhesiveness, and enables a long-time cell culture. Provided is a hydrogel (1) including: a tetra-armed polymer (2) containing polyethylene glycol as a backbone, and containing one or more electrophilic functional groups or nucleophilic functional groups in at least one of a side chain and a terminal; and a linear polymer (3) containing two or more nucleophilic functional groups or electrophilic functional groups in at least one of a side chain and a terminal; the tetra-armed polymer (2) and the linear polymer (3) being cross-linked with each other; wherein the hydrogel is characterized in that the linear polymer (3) is protein, peptide, or polysaccharide, that the electrophilic functional group(s) is/are one or more selected from the group consisting of maleimidyl, N-hydroxy-succinimidyl (NHS), sulfosuccinimidyl, phthalimidyl, imidazoyl, acryloyl, and nitrophenyl, and that the nucleophilic functional group(s) is/are one or more selected from the group consisting of thiol, amino, and —CO2PhNO2.

公开(公告)号：US20240269344A1

公开(公告)日：2024-08-15

申请号：US18434544

申请日：2024-02-06

申请人： Chihiro KUBO ,  Naoki Satoh ,  Hidekazu Yaginuma

发明人： Chihiro KUBO ,  Naoki Satoh ,  Hidekazu Yaginuma

IPC分类号： A61L27/26 ,  A61L26/00

CPC分类号： A61L27/26 ,  A61L26/0052 ,  A61L26/0066 ,  A61L2300/414 ,  A61L2300/64

摘要： A method for producing porous carrier having high porosity that is excellent in shape retention can be performed. A porous structure is formed by: preparing a liquid mixture that has at least a first polypeptide and a second polypeptide; and adding transglutaminase to the liquid mixture, and allowing the resulting mixture to react to form a gel.

公开(公告)号：US20220002704A1

公开(公告)日：2022-01-06

申请号：US17479037

申请日：2021-09-20

申请人： Naoki Satoh ,  Hidekazu Yaginuma ,  Tomoyuki Aratani ,  Momoko Shionoiri ,  Natsuko Iwashita ,  Tatsuya Sameshima ,  Takehiro Yamazaki

发明人： Naoki Satoh ,  Hidekazu Yaginuma ,  Tomoyuki Aratani ,  Momoko Shionoiri ,  Natsuko Iwashita ,  Tatsuya Sameshima ,  Takehiro Yamazaki

IPC分类号： C12N11/04

摘要： This invention is to develop a production method for a cell culture carrier comprising a hydrogel having high shape retainability, and cell culture carrier production device, and to provide a structure composed of a cell culture carrier produced using the same.
The production method comprises a retention step of retaining on a support material a first solution containing a multiple branching polymer comprising polyethylene glycol as the backbone, and having at least one functional group which is one of a nucleophilic functional group and an electrophilic functional group at a side chain(s) and/or a terminal(s), and a gel formation step of forming one or more dot-shaped hydrogels in which a second solution containing a multiple branching polymer comprising polyethylene glycol as the backbone, and having at least one functional group which is the other one of a nucleophilic functional group and an electrophilic functional group at a side chain and/or a terminal, is discharged by a droplet discharge device to land in contact with the first solution retained on the support material.

公开(公告)号：US20190309257A1

公开(公告)日：2019-10-10

申请号：US16375490

申请日：2019-04-04

申请人： Tomoyuki Aratani ,  Chihiro Kubo ,  Hidekazu Yaginuma ,  Naoki Satoh

发明人： Tomoyuki Aratani ,  Chihiro Kubo ,  Hidekazu Yaginuma ,  Naoki Satoh

IPC分类号： C12N5/00 ,  C12M1/12 ,  C12N5/071

摘要： Provided is a method for producing a cell locating plate, including: a step of laminating a structural layer over a plane of a base material, the structural layer being a layer that is formed of a cell non-adhesive material and in which a plurality of holes are formed; a step of coating a coating liquid in the holes and over the plane of the base material exposed through the holes; and a step of discharging a cell suspension onto the plane coated with the coating liquid.

公开(公告)号：US10509290B2

公开(公告)日：2019-12-17

申请号：US15885915

申请日：2018-02-01

申请人： Sukchan Kim ,  Tohru Yashiro ,  Hidekazu Yaginuma ,  Yoshihisa Naijo ,  Kohji Takeuchi ,  Yasuhiro Takahashi ,  Atsushi Ohshima

发明人： Sukchan Kim ,  Tohru Yashiro ,  Hidekazu Yaginuma ,  Yoshihisa Naijo ,  Kohji Takeuchi ,  Yasuhiro Takahashi ,  Atsushi Ohshima

IPC分类号： G02F1/155 ,  G02F1/1523 ,  G02F1/153 ,  G02F1/1524 ,  G02F1/161 ,  G02C7/02 ,  C09K9/02

摘要： An electrochromic apparatus includes a first substrate, a first electrode layer, an electrochromic layer, an electrolyte layer, a second substrate, a second electrode layer, a first extraction electrode layer, a second extraction electrode layer, and a partition wall. The first extraction electrode layer contacts the first electrode layer and is isolated from the second electrode layer and the electrochromic layer. The second extraction electrode layer contacts the second electrode layer and is isolated from the first electrode layer and the electrolyte layer. The partition wall is electrically insulative and sandwiched between the first extraction electrode layer and the electrolyte layer and between the second extraction electrode layer and the electrolyte layer.

公开(公告)号：US08693939B2

公开(公告)日：2014-04-08

申请号：US12929249

申请日：2011-01-11

申请人： Hidenori Tomono ,  Yasuo Katano ,  Yukimichi Someya ,  Tsuneo Kurotori ,  Yuko Arizumi ,  Shigenobu Hirano ,  Hidekazu Yaginuma ,  Shigeo Takeuchi ,  Fuminari Kaneko

发明人： Hidenori Tomono ,  Yasuo Katano ,  Yukimichi Someya ,  Tsuneo Kurotori ,  Yuko Arizumi ,  Shigenobu Hirano ,  Hidekazu Yaginuma ,  Shigeo Takeuchi ,  Fuminari Kaneko

IPC分类号： G03G15/20

CPC分类号： G03G15/2096

摘要： A disclosed fixing device includes a fixer application unit configured to apply a fixer containing a softener, capable of softening resin by dissolving or swelling at least a part of the resin, and water to resin particles formed on a recording medium such that the resin particles are fixed on the recording medium. The fixing unit may further include an anti-tack agent application unit configured to apply a liquid anti-tack agent immiscible with the softener to surfaces of the resin particles that are mixed with the softener by the application of the fixer containing the softener.

摘要翻译： 所公开的定影装置包括定影剂施加单元，其被配置为施加含有柔软剂的定影剂，其能够通过将至少一部分树脂溶解或溶胀而使树脂软化，并将水施加到形成在记录介质上的树脂颗粒，使得树脂颗粒为 固定在记录介质上。 定影单元还可以包括抗粘剂施用单元，其构造成通过施加含有软化剂的定影剂，将与软化剂不混溶的液体防粘剂施加到与软化剂混合的树脂颗粒的表面。

公开(公告)号：US08445628B2

公开(公告)日：2013-05-21

申请号：US12827079

申请日：2010-06-30

申请人： Yasuo Yamanaka ,  Tadakatsu Harada ,  Hidekazu Yaginuma ,  Masanobu Munekata ,  Kenji Tajima ,  Yasuharu Satoh ,  Tokuo Matsushima

发明人： Yasuo Yamanaka ,  Tadakatsu Harada ,  Hidekazu Yaginuma ,  Masanobu Munekata ,  Kenji Tajima ,  Yasuharu Satoh ,  Tokuo Matsushima

IPC分类号： C08G63/08

CPC分类号： C08G63/06

摘要： Disclosed is a copolymer resin composition including a lactic acid copolymer, the lactic acid copolymer containing monomer units represented by the following chemical formulas [1], [2], and [3], wherein a content of a monomer unit represented by the chemical formula [3] is 50 mol % or more and 95 mol % or less, a weight-average molecular weight of the lactic acid copolymer is 20,000 or more and 1,000,000 or less, and a deflection temperature of the lactic acid copolymer under load is 65° C. or higher and 100° C. or lower at a bending stress of 1.80 MPa.

摘要翻译： 公开了包含乳酸共聚物的共聚物树脂组合物，所述乳酸共聚物含有由以下化学式[1]，[2]和[3]表示的单体单元，其中由化学式 [3]为50摩尔％以上且95摩尔％以下，乳酸共聚物的重均分子量为20,000以上且1,000,000以下，负载时的乳酸共聚物的挠曲温度为65度 ℃以上且弯曲应力为1.80MPa时为100℃以下。

公开(公告)号：US11097544B2

公开(公告)日：2021-08-24

申请号：US16672572

申请日：2019-11-04

申请人： Koichi Muramatsu ,  Takahiko Matsumoto ,  Shinnosuke Koshizuka ,  Satoshi Okano ,  Satoshi Nakazawa ,  Yuzuru Kuramochi ,  Ryuya Mashiko ,  Takeshi Akai ,  Daisuke Takagi ,  Tomoaki Nakayama ,  Hidekazu Yaginuma ,  Hiroshi Fujie ,  Manabu Yamanaka

发明人： Koichi Muramatsu ,  Takahiko Matsumoto ,  Shinnosuke Koshizuka ,  Satoshi Okano ,  Satoshi Nakazawa ,  Yuzuru Kuramochi ,  Ryuya Mashiko ,  Takeshi Akai ,  Daisuke Takagi ,  Tomoaki Nakayama ,  Hidekazu Yaginuma ,  Hiroshi Fujie ,  Manabu Yamanaka

IPC分类号： B41J2/14

摘要： Provided is a liquid discharging head including: a membranous member including a discharging port through which a liquid is discharged; and a displacement member disposed at membranous member's one side at which the liquid to be discharged through the discharging port is provided and configured to displace a position of the membranous member to cause the liquid to be discharged through the discharging port.

公开(公告)号：US20180231857A1

公开(公告)日：2018-08-16

申请号：US15885915

申请日：2018-02-01

申请人： Sukchan KIM ,  Tohru Yashiro ,  Hidekazu Yaginuma ,  Yoshihisa Naijo ,  Kohji Takeuchi ,  Yasuhiro Takahashi ,  Atsushi Ohshima

发明人： Sukchan KIM ,  Tohru Yashiro ,  Hidekazu Yaginuma ,  Yoshihisa Naijo ,  Kohji Takeuchi ,  Yasuhiro Takahashi ,  Atsushi Ohshima

IPC分类号： G02F1/155 ,  G02F1/15 ,  G02F1/153

CPC分类号： G02F1/155 ,  C09K9/02 ,  C09K2211/1029 ,  G02C7/02 ,  G02F1/15245 ,  G02F1/1525 ,  G02F1/1533 ,  G02F1/161

摘要： An electrochromic apparatus includes a first substrate, a first electrode layer, an electrochromic layer, an electrolyte layer, a second substrate, a second electrode layer, a first extraction electrode layer, a second extraction electrode layer, and a partition wall. The first extraction electrode layer contacts the first electrode layer and is isolated from the second electrode layer and the electrochromic layer. The second extraction electrode layer contacts the second electrode layer and is isolated from the first electrode layer and the electrolyte layer. The partition wall is electrically insulative and sandwiched between the first extraction electrode layer and the electrolyte layer and between the second extraction electrode layer and the electrolyte layer.

公开(公告)号：US20110002718A1

公开(公告)日：2011-01-06

申请号：US12825683

申请日：2010-06-29

申请人： Yasuo Katano ,  Tsuneo Kurotori ,  Yuko Arizumi ,  Shigeo Takeuchi ,  Hidekazu Yaginuma ,  Fuminari Kaneko ,  Yukimichi Someya ,  Shigenobu Hirano ,  Hidenori Tomono

发明人： Yasuo Katano ,  Tsuneo Kurotori ,  Yuko Arizumi ,  Shigeo Takeuchi ,  Hidekazu Yaginuma ,  Fuminari Kaneko ,  Yukimichi Someya ,  Shigenobu Hirano ,  Hidenori Tomono

IPC分类号： G03G15/20 ,  G03G9/12 ,  G03G9/13 ,  G03G13/20

CPC分类号： G03G11/00

摘要： To provide a fixing solution for fixing fine resin particles to a recording medium, the fixing solution including: a diluent which contains water; a foaming agent which allows the fixing solution to be in the form of foam; and a solid plasticizer which is solid at normal temperature and soluble in the diluent, and which softens or swells at least part of the fine resin particles while dissolved in the diluent.

摘要翻译： 为了提供将树脂微粒固定在记录介质上的定影液，定影液包括：含有水的稀释剂; 使定影液成泡沫状的发泡剂; 和固体增塑剂，其在常温下为固体且可溶于稀释剂，并且在溶解在稀释剂中时使至少部分细小树脂颗粒软化或溶胀。