公开(公告)号：US20180169068A1

公开(公告)日：2018-06-21

申请号：US15839333

申请日：2017-12-12

Applicant: NESTEC SA

Inventor： Rondo P. Middleton ,  Brian M. Zanghi ,  Serge Andre Dominique Rezzi ,  Steven S. Hannah

IPC: A61K31/4015 ,  A61K31/198 ,  A61K31/4168 ,  A61K38/05 ,  A61K31/401 ,  A61K31/522 ,  A61K31/05 ,  A61K31/047 ,  A61K31/133 ,  A61K31/7068 ,  A61K31/197 ,  A61K31/202 ,  A61K31/192 ,  A61K31/7004 ,  A61K31/216 ,  A61K31/405 ,  A61K31/404 ,  A61P19/10 ,  A61P19/08 ,  A61P25/00 ,  A61P37/00 ,  A61P9/00 ,  A61P3/10 ,  A61P35/00 ,  A61P35/02 ,  A61P17/00 ,  A61P19/00 ,  A61K9/00 ,  A23K20/174 ,  A23K20/147 ,  A23K20/158 ,  A23K20/163 ,  A23K50/40

Abstract: Bone mineral content, 25(OH) vitamin D3, or 1,25(OH)2 vitamin D3 in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the bone mineral content, 25(OH) vitamin D3, or 1,25(OH)2 vitamin D3 or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the bone mineral content, 25(OH) vitamin D3, or 1,25(OH)2 vitamin D3.

公开(公告)号：US20180168195A1

公开(公告)日：2018-06-21

申请号：US15839370

申请日：2017-12-12

Applicant: NESTEC SA

Inventor： Rondo P. Middleton ,  Brain M. Zanghi ,  Serge Andre Dominique Rezzi ,  Steven S. Hannah

IPC: A23K50/40 ,  A61K31/661 ,  A61P3/06 ,  A61P9/00 ,  A61P9/10 ,  A61P29/00 ,  A61K31/191 ,  A61K31/355 ,  A61K31/575 ,  A61K31/7068 ,  A61K31/19 ,  A61K31/16 ,  A61K31/194 ,  A61K31/708 ,  A61K31/20 ,  A61K31/202 ,  A23K20/142 ,  A23K20/147 ,  A23K20/158 ,  A23K20/163

Abstract: Cholesterol, high-density lipoproteins, and low-density lipoproteins in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the cholesterol, high-density lipoproteins, or low-density lipoproteins or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates cholesterol, high-density lipoproteins, or low-density lipoproteins.

公开(公告)号：US20180168196A1

公开(公告)日：2018-06-21

申请号：US15839384

申请日：2017-12-12

Applicant: NESTEC SA

Inventor： Rondo P. Middleton ,  Brian M. Zanghi ,  Serge Andre Dominique Rezzi ,  Steven S. Hannah

IPC: A23K50/40 ,  A61K31/575 ,  A61K31/192 ,  A61K31/197 ,  A61K31/20 ,  A61K31/047 ,  A61K31/405 ,  A61K31/202 ,  A61K31/7004 ,  A61K31/4418 ,  A61K31/198 ,  A61P1/14 ,  A61P1/00 ,  A61P17/00 ,  A61P31/00 ,  A61P37/00 ,  A23K20/142 ,  A23K20/147 ,  A23K20/163 ,  A23K20/158

Abstract: A specific bacterium in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the specific type of bacterium or to decrease the amount of a compound which positively or negatively modulates the specific type of bacterium. The specific type of bacterium can be one or more of Bifidobacterium, Lactobacillus, or Clostridium perfringens.

公开(公告)号：US09596870B2

公开(公告)日：2017-03-21

申请号：US14310359

申请日：2014-06-20

Applicant: NESTEC SA

Inventor： Brian M. Zanghi ,  Arleigh J. Reynolds ,  Rondo P. Middleton

IPC: A23K1/17 ,  A23K1/18 ,  A23K20/147 ,  A23K20/158 ,  A23K20/163 ,  A23K50/40

CPC classification number: A23K20/147 ,  A23K20/142 ,  A23K20/158 ,  A23K20/163 ,  A23K50/40

Abstract: Compositions and methods are provided for improving canine exercise performance. The compositions are pre-exercise supplements that generally comprise (a) about 35% to about 60% protein or amino acids, comprising one or more structural proteins, one or more bioavailable proteins and one or more branched chain amino acids; (b) about 20% to about 38% fat, comprising at least one source of medium chain triglycerides; and (c) about 5% to about 25% carbohydrate. The methods involve administering the supplement to the animal within about 30-60 minutes before the beginning of the exercise session. The supplements can be administered in conjunction with one or more other exercise performance-enhancing or recovery agents.

公开(公告)号：US20180169127A1

公开(公告)日：2018-06-21

申请号：US15839359

申请日：2017-12-12

Applicant: NESTEC SA

Inventor： Rondo P. Middleton ,  Brian M. Zanghi ,  Serge Andre Dominique Rezzi ,  Steven S. Hannah

IPC: A61K31/7056 ,  A61K31/194 ,  A61K31/198 ,  A61K31/23 ,  A61K31/7072 ,  A61K31/197 ,  A61K31/683 ,  A61K31/235 ,  A61K31/225 ,  A61K31/255 ,  A61K31/405 ,  G01N33/50 ,  A23K20/147 ,  A23K20/158 ,  A23K20/163 ,  A23K50/42 ,  A23K50/48

Abstract: White blood cells and/or neutrophils in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the white blood cells and/or neutrophils or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the white blood cells and/or neutrophils.

公开(公告)号：US20150004279A1

公开(公告)日：2015-01-01

申请号：US14310359

申请日：2014-06-20

Applicant: NESTEC SA

Inventor： Brian M. Zanghi ,  Arleigh J. Reynolds ,  Rondo P. Middleton

IPC: A23K1/18

CPC classification number: A23K20/147 ,  A23K20/142 ,  A23K20/158 ,  A23K20/163 ,  A23K50/40

Abstract: Compositions and methods are provided for improving canine exercise performance. The compositions are pre-exercise supplements that generally comprise (a) about 35% to about 60% protein or amino acids, comprising one or more structural proteins, one or more bioavailable proteins and one or more branched chain amino acids; (b) about 20% to about 38% fat, comprising at least one source of medium chain triglycerides; and (c) about 5% to about 25% carbohydrate. The methods involve administering the supplement to the animal within about 30-60 minutes before the beginning of the exercise session. The supplements can be administered in conjunction with one or more other exercise performance-enhancing or recovery agents.

Abstract translation: 提供了改善犬运动性能的组合和方法。 组合物是运动前补充剂，其通常包含（a）约35％至约60％的蛋白质或氨基酸，其包含一种或多种结构蛋白质，一种或多种生物可利用蛋白质和一种或多种支链氨基酸; （b）约20％至约38％的脂肪，包含至少一种中链甘油三酯源; 和（c）约5％至约25％的碳水化合物。 所述方法包括在运动开始之前约30-60分钟内对动物施用补充物。 补充剂可以与一种或多种其它锻炼性能增强或恢复剂一起施用。

公开(公告)号：US20140309137A1

公开(公告)日：2014-10-16

申请号：US14314088

申请日：2014-06-25

Applicant: NESTEC SA

Inventor： Yuanlong Pan ,  Stephen S. Hannah ,  Rondo P. Middleton

IPC: C12Q1/68

CPC classification number: C12Q1/6881 ,  C12Q1/6876 ,  C12Q1/6883 ,  C12Q2600/124 ,  C12Q2600/158 ,  G01N2800/044

Abstract: Gene expression profiles associated with improved or maintained lean body mass or reduced body fat are disclosed. The gene expression profiles were determined in adipose, liver, and muscle tissue of animals subjected to lean-promoting regimens such as consumption of a high protein diet, ingestion of conjugated linolenic acid, and/or increased exercise. Methods of using such profiles for the identification of pharmaceutical substances, nutraceutical substances, dietary substances, or treatment regimens that modulate or contribute to desired phenotypes in animals are also disclosed

Abstract translation: 公开了与改善或维持的瘦体重或减少的身体脂肪相关的基因表达谱。 在经受瘦素促进方案的动物的脂肪，肝脏和肌肉组织中测定基因表达谱，例如消耗高蛋白饮食，摄入共轭亚麻酸和/或增加运动。 还公开了使用这种简档来鉴定在动物中调节或有助于期望的表型的药物，营养药物，膳食物质或治疗方案的方法

公开(公告)号：US20180168194A1

公开(公告)日：2018-06-21

申请号：US15839347

申请日：2017-12-12

Applicant: NESTEC SA

Inventor： Rondo P. Middleton ,  Brian M. Zanghi ,  Serge Andre Dominique Rezzi ,  Steven S. Hannah

IPC: A23K50/40 ,  A61K33/42 ,  A61K38/07 ,  A61K31/198 ,  A61K31/205 ,  A61K31/047 ,  A61K31/17 ,  A61K31/19 ,  A61K31/7004 ,  A61K31/405 ,  A61K31/513 ,  A61K31/191 ,  A61K31/197 ,  A61K31/185 ,  A61K31/661 ,  A61K31/4166 ,  A61K31/7068 ,  A61K31/4425 ,  A61K31/575 ,  A61K31/194 ,  A61P1/16 ,  A61P13/12 ,  A61P19/08 ,  A61P5/00 ,  A61P1/00 ,  A61P1/18 ,  A61P9/00 ,  A61P21/00 ,  A61P7/00 ,  A61P25/00 ,  A61P1/12 ,  A23K20/142 ,  A23K20/147 ,  A23K20/163 ,  A23K20/158

Abstract: A specific type of organ health marker in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the specific type of organ health marker or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the specific type of organ health marker. The specific type of organ health marker can be one or more of phosphorus, alkaline phosphatase, aspartate aminotransferase, or gamma-glutamyltransferase.

公开(公告)号：US20170150738A1

公开(公告)日：2017-06-01

申请号：US15430729

申请日：2017-02-13

Applicant: NESTEC SA

Inventor： Brian M. Zanghi ,  Arleigh J. Reynolds ,  Rondo P. Middleton

IPC: A23K20/147 ,  A23K20/142 ,  A23K20/163 ,  A23K50/40 ,  A23K20/158

CPC classification number: A23K20/147 ,  A23K20/142 ,  A23K20/158 ,  A23K20/163 ,  A23K50/40

Abstract: Compositions and methods are provided for improving canine exercise performance. The compositions are pre-exercise supplements that generally comprise (a) about 35% to about 60% protein or amino acids, comprising one or more structural proteins, one or more bioavailable proteins and one or more branched chain amino acids; (b) about 20% to about 38% fat, comprising at least one source of medium chain triglycerides; and (c) about 5% to about 25% carbohydrate. The methods involve administering the supplement to the animal within about 30-60 minutes before the beginning of the exercise session. The supplements can be administered in conjunction with one or more other exercise performance-enhancing or recovery agents.