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22 条记录 (耗时 0.031 秒)

    4-(2-Pyridylamino)phenylacetic acid derivatives
    3.
    发明授权
    4-(2-Pyridylamino)phenylacetic acid derivatives 失效
    4-（2-吡啶基氨基）苯乙酸衍生物

    公开(公告)号：US4256753A

    公开(公告)日：1981-03-17

    申请号：US95572

    申请日：1979-11-19

    申请人： Hitoshi Uno ,  Yasutaka Nagai ,  Katsuhiko Hino ,  Hideo Nakamura

    发明人： Hitoshi Uno ,  Yasutaka Nagai ,  Katsuhiko Hino ,  Hideo Nakamura

    IPC分类号： A61K31/44 ,  A61K31/4402 ,  A61K31/4418 ,  A61P25/04 ,  A61P29/00 ,  C07D213/74

    CPC分类号： C07D213/74

    摘要： Novel 4-(2'-pyridylamino)phenylacetic acid derivatives of the formula: ##STR1## wherein R.sub.1 is hydrogen, a halogen, a lower alkyl having 1 to 3 carbon atoms, or nitro, R.sub.2 is hydrogen, a halogen, or a lower alkyl having 1 to 3 carbon atoms, R.sub.3 is hydrogen, a halogen, or a lower alkyl having 1 to 3 carbon atoms, R.sub.4 is hydrogen or a lower alkyl having 1 to 3 carbon atoms, R.sub.5 is hydrogen or --CH.sub.2 CH.sub.2 OR.sub.6 wherein R.sub.6 is a lower alkyl having 2 or 3 carbon atoms and being substituted with 1 or 2 hydroxy groups, provided that R.sub.1 or R.sub.2 is not 4-halogen, or pharmaceutically acceptable salts thereof, and a process for the preparation thereof, pharmaceutical composition of said compounds, and a method of using said compounds as anti-inflammatory and analgesic agents. They have excellent anti-inflammatory and analgesic activities with an extremely weak ulcerogenicity in the gastrointestinal tract. Some of the compounds have superior inhibitory activity against chronic inflammation mediated by cellular immunity.

    摘要翻译： 下式的新型4-（2'-吡啶基氨基）苯乙酸衍生物：其中R 1是氢，卤素，具有1至3个碳原子的低级烷基或硝基，R 2是氢，卤素或低级 具有1至3个碳原子的烷基，R 3是氢，卤素或具有1至3个碳原子的低级烷基，R 4是氢或具有1至3个碳原子的低级烷基，R 5是氢或-CH 2 CH 2 OR 6，其中R 6是 具有2或3个碳原子并且被1或2个羟基取代的低级烷基，条件是R1或R2不是4-卤素，或其药学上可接受的盐，及其制备方法，所述化合物的药物组合物和 使用所述化合物作为抗炎和止痛剂的方法。 它们具有优异的抗炎和止痛活性，在胃肠道中具有非常弱的溃疡形成能力。 一些化合物对由细胞免疫介导的慢性炎症具有优异的抑制活性。

    Ultrasonic transducer
    5.
    发明授权
    Ultrasonic transducer 失效
    超声波换能器

    公开(公告)号：US4676106A

    公开(公告)日：1987-06-30

    申请号：US805608

    申请日：1985-12-06

    申请人： Yasutaka Nagai ,  Susumu Enjoji

    发明人： Yasutaka Nagai ,  Susumu Enjoji

    IPC分类号： A61B8/00 ,  B06B1/06 ,  G01N29/06

    CPC分类号： B06B1/0622 ,  A61B8/4494

    摘要： A phased-array ultrasonic transducer for an ultrasonograph is provided in which electrical signals are supplied to ultrasonic transducer elements to generate ultrasonic beams for diagnostic scanning. The ultrasonic transducer comprises a number of ultrasonic transducer elements arranged in the form of an array, a signal electrode plate coupled to the signal-supply side of the transducer elements and connected to a transmitter-receiver circuit by means of signal wires, and an earth electrode plate connected to the earth side of the transducer elements. The earth electrode plate is divided into a plurality of split earth electrode plates corresponding to ultrasonic transducer groups each including a plurality of adjacent transducer elements so that the split earth electrode plates are grounded independently. Thus, clearer and more accurate ultrasonic images can be obtained without undesired signals attributed to any other transducer elements than the transducer element in operation being produced or artifact appearing on the ultrasonic image.

    摘要翻译： 提供了一种用于超声波诊断仪的相控阵超声波换能器，其中电信号被提供给超声换能器元件以产生用于诊断扫描的超声波束。 超声波换能器包括以阵列形式布置的多个超声换能器元件，耦合到换能器元件的信号供给侧的信号电极板，并通过信号线连接到发射机 - 接收机电路，并且接地 电极板连接到换能器元件的接地侧。 接地电极板被分成多个对应于每个包括多个相邻换能器元件的超声波换能器组的分离接地电极板，使得分离接地电极板独立接地。 因此，可以获得更清晰和更准确的超声波图像，而不产生归因于任何其它换能器元件而不是产生运行中的换能器元件或在超声波图像上出现伪像的信号。

    Method and apparatus for exhaust gas control of an internal combustion engine
    10.
    发明授权
    Method and apparatus for exhaust gas control of an internal combustion engine 有权
    用于内燃机排气控制的方法和装置

    公开(公告)号：US09005558B2

    公开(公告)日：2015-04-14

    申请号：US14122765

    申请日：2012-05-30

    申请人： Masao Watanabe ,  Shigeharu Takagi ,  Keisuke Kishita ,  Noboru Otake ,  Akira Morikawa ,  Takuto Hirose ,  Yasutaka Nagai

    发明人： Masao Watanabe ,  Shigeharu Takagi ,  Keisuke Kishita ,  Noboru Otake ,  Akira Morikawa ,  Takuto Hirose ,  Yasutaka Nagai

    IPC分类号： B01D53/94 ,  F01N3/10 ,  F01N3/18 ,  F01N3/22 ,  F01N9/00 ,  F02D41/02 ,  F01N13/00

    CPC分类号： F01N3/225 ,  B01D53/9431 ,  B01D53/9459 ,  F01N9/002 ,  F01N13/011 ,  F02D41/027 ,  F02D2200/0802 ,  Y02T10/47

    摘要： An exhaust gas control apparatus for an internal combustion engine includes: a NOx purification catalyst arranged in an exhaust passage of the internal combustion engine; a degradation degree estimating unit estimating a degradation degree of the NOx purification catalyst; and an air-fuel ratio control unit adjusting an air-fuel ratio of exhaust gas flowing into the NOx purification catalyst, wherein, until the estimated degradation degree of the NOx purification catalyst reaches a predetermined degradation degree, the air-fuel ratio control unit adjusts the air-fuel ratio of the exhaust gas to a rich air-fuel ratio, and, when the estimated degradation degree of the NOx purification catalyst exceeds the predetermined degradation degree, the air-fuel ratio control unit changes the air-fuel ratio of the exhaust gas from the rich air-fuel ratio to a lean air-fuel ratio so that the NOx purification catalyst is regenerated.

    摘要翻译： 一种用于内燃机的排气控制装置，包括：排出在内燃机的排气通道中的NOx净化催化剂; 劣化度估计单元，估计所述NOx净化催化剂的劣化程度; 以及调节流入所述NOx净化催化剂的废气的空燃比的空燃比控制部，其中，在所述NOx净化催化剂的所述劣化程度的估计值达到预定的劣化程度之前，所述空燃比控制部调整 所述排气的空燃比为浓空燃比，并且当所述NOx净化催化剂的所述劣化程度的估计值超过所述规定的劣化程度时，所述空燃比控制部将所述空燃比的空燃比变更为 从富空燃比排出的废气为稀空燃比，使得NOx净化催化剂再生。