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1.发明授权公开(公告)号：US08389435B2
公开(公告)日：2013-03-05
申请号：US12295454
申请日：2007-03-30
申请人： Masahide Miura , Nobuyuki Takagi , Shinichi Matsumoto , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Yasuo Ikeda
发明人： Masahide Miura , Nobuyuki Takagi , Shinichi Matsumoto , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Yasuo Ikeda
IPC分类号： B01J23/00 , B01J23/10 , B01J23/42 , B01J23/44 , B01J23/08 , B01J8/02 , B01J8/00 , B01D53/56 , B01D53/86 , B01D53/94 , C01B21/00 , C01B23/00 , C01B25/00 , C01B31/00 , C01B33/00 , C01B35/00 , C01G28/00 , C01G30/00 , B32B5/16 , B32B9/00 , B32B15/02 , B32B17/02 , B32B19/00 , B32B21/02 , B32B23/02 , B32B27/02
CPC分类号： B01J37/0221 , B01D53/945 , B01D2255/206 , B01J23/63 , B01J35/008 , B01J35/026 , B01J35/10 , B01J35/1014 , B01J37/0234 , Y02T10/22 , Y10T428/2991
摘要： A metal oxide catalyst carrier particle has a center portion and an outer skin portion each containing a first metal oxide and a second metal oxide. The center portion and the outer skin portion are different in composition. The mole fraction of the metal of the first metal oxide is higher in the center portion than in the outer skin portion and the mole fraction of the metal of the second metal oxide is higher in the outer skin portion than in the center portion. The second metal oxide is selected from the group consisting of rare earth oxides, except for ceria, and alkali earth metal oxides. In addition, platinum is supported on the metal oxide catalyst carrier particle, thus forming an exhaust gas purification catalyst.
摘要翻译： 金属氧化物催化剂载体颗粒具有分别含有第一金属氧化物和第二金属氧化物的中心部分和外皮部分。 中心部分和外皮部分的组成不同。 第一金属氧化物的金属的摩尔分数在中心部分高于外皮部分，并且第二金属氧化物的金属的摩尔分数在外皮部分中比在中心部分高。 第二金属氧化物选自除二氧化铈以外的稀土氧化物和碱土金属氧化物。 此外，铂负载在金属氧化物催化剂载体颗粒上，从而形成废气净化催化剂。
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公开(公告)号：US4256753A
公开(公告)日：1981-03-17
申请号：US95572
申请日：1979-11-19
申请人： Hitoshi Uno , Yasutaka Nagai , Katsuhiko Hino , Hideo Nakamura
发明人： Hitoshi Uno , Yasutaka Nagai , Katsuhiko Hino , Hideo Nakamura
IPC分类号： A61K31/44 , A61K31/4402 , A61K31/4418 , A61P25/04 , A61P29/00 , C07D213/74
CPC分类号： C07D213/74
摘要： Novel 4-(2'-pyridylamino)phenylacetic acid derivatives of the formula: ##STR1## wherein R.sub.1 is hydrogen, a halogen, a lower alkyl having 1 to 3 carbon atoms, or nitro, R.sub.2 is hydrogen, a halogen, or a lower alkyl having 1 to 3 carbon atoms, R.sub.3 is hydrogen, a halogen, or a lower alkyl having 1 to 3 carbon atoms, R.sub.4 is hydrogen or a lower alkyl having 1 to 3 carbon atoms, R.sub.5 is hydrogen or --CH.sub.2 CH.sub.2 OR.sub.6 wherein R.sub.6 is a lower alkyl having 2 or 3 carbon atoms and being substituted with 1 or 2 hydroxy groups, provided that R.sub.1 or R.sub.2 is not 4-halogen, or pharmaceutically acceptable salts thereof, and a process for the preparation thereof, pharmaceutical composition of said compounds, and a method of using said compounds as anti-inflammatory and analgesic agents. They have excellent anti-inflammatory and analgesic activities with an extremely weak ulcerogenicity in the gastrointestinal tract. Some of the compounds have superior inhibitory activity against chronic inflammation mediated by cellular immunity.
摘要翻译： 下式的新型4-（2'-吡啶基氨基）苯乙酸衍生物：其中R 1是氢，卤素，具有1至3个碳原子的低级烷基或硝基，R 2是氢，卤素或低级 具有1至3个碳原子的烷基，R 3是氢，卤素或具有1至3个碳原子的低级烷基，R 4是氢或具有1至3个碳原子的低级烷基，R 5是氢或-CH 2 CH 2 OR 6，其中R 6是 具有2或3个碳原子并且被1或2个羟基取代的低级烷基，条件是R1或R2不是4-卤素，或其药学上可接受的盐，及其制备方法，所述化合物的药物组合物和 使用所述化合物作为抗炎和止痛剂的方法。 它们具有优异的抗炎和止痛活性，在胃肠道中具有非常弱的溃疡形成能力。 一些化合物对由细胞免疫介导的慢性炎症具有优异的抑制活性。
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3.发明授权Dibenz[b,f]oxepin and dibenzo[b,f]thiepin derivatives, process for preparation thereof, method of using the same, and compositions thereof 失效二苯并[b，f]氧杂七环素和二苯并[b，f]硫蛋白衍生物，其制备方法，使用该方法及其组合物
公开(公告)号：US4238620A
公开(公告)日：1980-12-09
申请号：US13477
申请日：1979-02-21
申请人： Hitoshi Uno , Yasutaka Nagai , Hideo Nakamura
发明人： Hitoshi Uno , Yasutaka Nagai , Hideo Nakamura
IPC分类号： A61K31/335 , A61P25/04 , A61P29/00 , C07C41/26 , C07C43/295 , C07C59/68 , C07C65/34 , C07D295/194 , C07D313/14 , C07D337/14
CPC分类号： C07D295/194 , C07C323/00 , C07C41/22 , C07C41/26 , C07C59/68 , C07C65/34 , C07D313/14 , C07D337/14 , Y10S514/916
摘要： Novel dibenz[b,f]oxepin and dibenzo[b,f]thiepin derivatives of the formula ##STR1## wherein X is an oxygen or sulfur atom, each of R.sub.1 and R.sub.2 is a hydrogen atom or a methyl group, and R.sub.3 is a hydrogen atom or a 2-(2-hydroxyethoxy)ethyl group; provided that when R.sub.1 is a hydrogen atom, the group ##STR2## is a group other than a 1-carboxyethyl group; and when X is a sulfur atom, both R.sub.1 and R.sub.2 are methyl groups;and pharmaceutically acceptable salts of said compounds in which R.sub.3 is a hydrogen atom. Compositions of said compounds, processes for the preparation of said compounds, and a method of using said compounds are also provided. These novel compounds have excellent anti-inflammatory, analgesic and antipyretic activities.
摘要翻译： 新颖的二苯并[b，f]氧杂七环和二苯并[b，f]硫酮衍生物，其中X是氧或硫原子，R1和R2各自为氢原子或甲基，R3为 氢原子或2-（2-羟基乙氧基）乙基; 条件是当R1是氢原子时，基团
是除1-羧乙基以外的基团; 当X为硫原子时，R1和R2均为甲基; 和所述化合物的药学上可接受的盐，其中R 3是氢原子。 还提供了所述化合物的组合物，所述化合物的制备方法和使用所述化合物的方法。 这些新化合物具有优异的抗炎，止痛和解热活性。 -
4.发明授权公开(公告)号：US08601794B2
公开(公告)日：2013-12-10
申请号：US12599079
申请日：2008-05-09
申请人： Masanori Yamato , Takeru Yoshida , Nobuyuki Takagi , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Naoki Takahashi
发明人： Masanori Yamato , Takeru Yoshida , Nobuyuki Takagi , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Naoki Takahashi
CPC分类号： B01J38/10 , B01D53/9445 , B01D2255/1021 , B01D2255/206 , B01J23/42 , B01J23/63 , B01J23/96 , B01J38/12 , F01N3/2013 , F01N3/206 , F01N3/22 , F01N2240/16 , F01N2240/28 , F01N2610/04 , Y02A50/2324 , Y02T10/22 , Y02T10/26
摘要： A regeneration apparatus comprises a heater 2 which heats a catalyst 1 at the time of stopping fuel supply to an engine, a pump 4 which supplies an oxidizing gas or a reducing gas to the heated catalyst 1 and a switching valve 3. In the oxidizing step, catalytic poisons, for example hydrocarbon, which are absorbed on a noble metal are oxidized and removed. The particles of the noble metal become oxidized particles as pure oxide and the like. After the oxidizing step, the reducing step is carried out. In the reducing step, particles of the noble metal are reduced and re-dispersed on the support simultaneously and as a result, the particles of the noble metal become fine. Thus, a deteriorated catalyst can be regenerated without interrupting the use of catalyst and also without deteriorating the drivability.
摘要翻译： 再生装置包括加热器2，其在停止对发动机的燃料供给时加热催化剂1，向加热的催化剂1供给氧化气体或还原气体的泵4和切换阀3.在氧化步骤 吸附在贵金属上的催化毒物（例如烃）被氧化和去除。 贵金属的粒子成为纯氧化物等的氧化粒子。 在氧化步骤之后，进行还原步骤。 在还原步骤中，贵金属的颗粒同时还原并再分散在载体上，结果，贵金属的颗粒变细。 因此，可以在不中断催化剂的使用的情况下再生劣化的催化剂，并且也不会降低驱动性。
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5.发明申请公开(公告)号：US20100293921A1
公开(公告)日：2010-11-25
申请号：US12599079
申请日：2008-05-09
申请人： Masanori Yamato , Takeru Yoshida , Nobuyuki Takagi , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Naoki Takahashi
发明人： Masanori Yamato , Takeru Yoshida , Nobuyuki Takagi , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Naoki Takahashi
CPC分类号： B01J38/10 , B01D53/9445 , B01D2255/1021 , B01D2255/206 , B01J23/42 , B01J23/63 , B01J23/96 , B01J38/12 , F01N3/2013 , F01N3/206 , F01N3/22 , F01N2240/16 , F01N2240/28 , F01N2610/04 , Y02A50/2324 , Y02T10/22 , Y02T10/26
摘要： A regeneration apparatus comprises a heater 2 which heats a catalyst 1 at the time of stopping fuel supply to an engine, a pump 4 which supplies an oxidizing gas or a reducing gas to the heated catalyst 1 and a switching valve 3. In the oxidizing step, catalytic poisons, for example hydrocarbon, which are absorbed on a noble metal are oxidized and removed. The particles of the noble metal become oxidized particles as pure oxide and the like. After the oxidizing step, the reducing step is carried out. In the reducing step, particles of the noble metal are reduced and re-dispersed on the support simultaneously and as a result, the particles of the noble metal become fine. Thus, a deteriorated catalyst can be regenerated without interrupting the use of catalyst and also without deteriorating the drivability.
摘要翻译： 再生装置包括加热器2，其在停止对发动机的燃料供给时加热催化剂1，向加热的催化剂1供给氧化气体或还原气体的泵4和切换阀3.在氧化步骤 吸附在贵金属上的催化毒物（例如烃）被氧化和去除。 贵金属的粒子成为纯氧化物等的氧化粒子。 在氧化步骤之后，进行还原步骤。 在还原步骤中，贵金属的颗粒同时还原并再分散在载体上，结果，贵金属的颗粒变细。 因此，可以在不中断催化剂的使用的情况下再生劣化的催化剂，并且也不会降低驱动性。
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6.发明申请公开(公告)号：US20100004117A1
公开(公告)日：2010-01-07
申请号：US12295454
申请日：2007-03-30
申请人： Masahide Miura , Nobuyuki Takagi , Shinichi Matsumoto , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Yasuo Ikeda
发明人： Masahide Miura , Nobuyuki Takagi , Shinichi Matsumoto , Toshitaka Tanabe , Yasutaka Nagai , Kazuhiko Dohmae , Yasuo Ikeda
CPC分类号： B01J37/0221 , B01D53/945 , B01D2255/206 , B01J23/63 , B01J35/008 , B01J35/026 , B01J35/10 , B01J35/1014 , B01J37/0234 , Y02T10/22 , Y10T428/2991
摘要： A metal oxide catalyst carrier particle has a center portion and an outer skin portion each containing a first metal oxide and a second metal oxide. The center portion and the outer skin portion are different in composition. The mole fraction of the metal of the first metal oxide is higher in the center portion than in the outer skin portion and the mole fraction of the metal of the second metal oxide is higher in the outer skin portion than in the center portion. The second metal oxide is selected from the group consisting of rare earth oxides, except for ceria, and alkali earth metal oxides. In addition, platinum is supported on the metal oxide catalyst carrier particle, thus forming an exhaust gas purification catalyst.
摘要翻译： 金属氧化物催化剂载体颗粒具有分别含有第一金属氧化物和第二金属氧化物的中心部分和外皮部分。 中心部分和外皮部分的组成不同。 第一金属氧化物的金属的摩尔分数在中心部分高于外皮部分，并且第二金属氧化物的金属的摩尔分数在外皮部分比在中心部分高。 第二金属氧化物选自除二氧化铈以外的稀土氧化物和碱土金属氧化物。 此外，铂负载在金属氧化物催化剂载体颗粒上，从而形成废气净化催化剂。
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公开(公告)号：US5300355A
公开(公告)日：1994-04-05
申请号：US886424
申请日：1992-05-20
申请人： Naoto Mifune , Yasutaka Nagai , Masaaki Ashizawa , Kazuo Nishimoto , Takahiro Niwa , Shuji Ito , Masanori Hansaka
发明人： Naoto Mifune , Yasutaka Nagai , Masaaki Ashizawa , Kazuo Nishimoto , Takahiro Niwa , Shuji Ito , Masanori Hansaka
CPC分类号： F16F9/306 , B32B27/06 , Y10S428/90 , Y10T428/2495 , Y10T428/24967 , Y10T428/257 , Y10T428/26 , Y10T428/266 , Y10T428/31692 , Y10T428/31696 , Y10T428/31699 , Y10T428/31826 , Y10T428/31833
摘要： In order to provide a damping material exhibiting an excellent vibration damping property in a wide temperature range, according to the present invention, in a magnetic composite type damping material constructed by bonding an adhesive elastic sheet containing magnetic powder to a constraining plate such as a metal plate by using an adhesive, the adhesive elastic sheet is made of a composite material consisting of rubber elastomer, adhesive resin, plasticizer, magnetic powder, etc.Since not only is the damping material having a construction described above attracted by magnetic force against a vibration source, it also is provided with a superficial adhesiveness, and the excellent vibration damping property is exhibited in a wide temperature range by a synergistic effect of the magnetic force and the adhering force.
摘要翻译： 为了提供根据本发明的在宽温度范围内具有优异的振动阻尼特性的阻尼材料，在通过将包含磁性粉末的粘合弹性片粘合到诸如金属的约束板上而构成的磁性复合型阻尼材料中 通过使用粘合剂将粘合弹性片材用橡胶弹性体，粘合剂树脂，增塑剂，磁性粉末等组成的复合材料制成。由于不仅具有上述结构的阻尼材料被磁力抵抗振动吸收 来源，也具有表面粘合性，并且通过磁力和粘附力的协同效应，在宽温度范围内显示出优异的振动阻尼特性。
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8.发明授权公开(公告)号：US09005558B2
公开(公告)日：2015-04-14
申请号：US14122765
申请日：2012-05-30
申请人： Masao Watanabe , Shigeharu Takagi , Keisuke Kishita , Noboru Otake , Akira Morikawa , Takuto Hirose , Yasutaka Nagai
发明人： Masao Watanabe , Shigeharu Takagi , Keisuke Kishita , Noboru Otake , Akira Morikawa , Takuto Hirose , Yasutaka Nagai
CPC分类号： F01N3/225 , B01D53/9431 , B01D53/9459 , F01N9/002 , F01N13/011 , F02D41/027 , F02D2200/0802 , Y02T10/47
摘要： An exhaust gas control apparatus for an internal combustion engine includes: a NOx purification catalyst arranged in an exhaust passage of the internal combustion engine; a degradation degree estimating unit estimating a degradation degree of the NOx purification catalyst; and an air-fuel ratio control unit adjusting an air-fuel ratio of exhaust gas flowing into the NOx purification catalyst, wherein, until the estimated degradation degree of the NOx purification catalyst reaches a predetermined degradation degree, the air-fuel ratio control unit adjusts the air-fuel ratio of the exhaust gas to a rich air-fuel ratio, and, when the estimated degradation degree of the NOx purification catalyst exceeds the predetermined degradation degree, the air-fuel ratio control unit changes the air-fuel ratio of the exhaust gas from the rich air-fuel ratio to a lean air-fuel ratio so that the NOx purification catalyst is regenerated.
摘要翻译： 一种用于内燃机的排气控制装置，包括：排出在内燃机的排气通道中的NOx净化催化剂; 劣化度估计单元，估计所述NOx净化催化剂的劣化程度; 以及调节流入所述NOx净化催化剂的废气的空燃比的空燃比控制部，其中，在所述NOx净化催化剂的所述劣化程度的估计值达到预定的劣化程度之前，所述空燃比控制部调整 所述排气的空燃比为浓空燃比，并且当所述NOx净化催化剂的所述劣化程度的估计值超过所述规定的劣化程度时，所述空燃比控制部将所述空燃比的空燃比变更为 从富空燃比排出的废气为稀空燃比，使得NOx净化催化剂再生。
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9.发明申请公开(公告)号：US20140134087A1
公开(公告)日：2014-05-15
申请号：US14122765
申请日：2012-05-30
申请人： Masao Watanabe , Shigeharu Takagi , Keisuke Kishita , Noboru Otake , Akira Morikawa , Takuto Hirose , Yasutaka Nagai
发明人： Masao Watanabe , Shigeharu Takagi , Keisuke Kishita , Noboru Otake , Akira Morikawa , Takuto Hirose , Yasutaka Nagai
CPC分类号： F01N3/225 , B01D53/9431 , B01D53/9459 , F01N9/002 , F01N13/011 , F02D41/027 , F02D2200/0802 , Y02T10/47
摘要： An exhaust gas control apparatus for an internal combustion engine includes: a NOx purification catalyst arranged in an exhaust passage of the internal combustion engine; a degradation degree estimating unit estimating a degradation degree of the NOx purification catalyst; and an air-fuel ratio control unit adjusting an air-fuel ratio of exhaust gas flowing into the NOx purification catalyst, wherein, until the estimated degradation degree of the NOx purification catalyst reaches a predetermined degradation degree, the air-fuel ratio control unit adjusts the air-fuel ratio of the exhaust gas to a rich air-fuel ratio, and, when the estimated degradation degree of the NOx purification catalyst exceeds the predetermined degradation degree, the air-fuel ratio control unit changes the air-fuel ratio of the exhaust gas from the rich air-fuel ratio to a lean air-fuel ratio so that the NOx purification catalyst is regenerated.
摘要翻译： 一种用于内燃机的排气控制装置，包括：排出在内燃机的排气通道中的NOx净化催化剂; 劣化度估计单元，估计所述NOx净化催化剂的劣化程度; 以及调节流入所述NOx净化催化剂的废气的空燃比的空燃比控制部，其中，在所述NOx净化催化剂的所述劣化程度的估计值达到预定的劣化程度之前，所述空燃比控制部调整 所述排气的空燃比为浓空燃比，并且当所述NOx净化催化剂的所述劣化程度的估计值超过所述规定的劣化程度时，所述空燃比控制部将所述空燃比的空燃比变更为 从富空燃比排出的废气为稀空燃比，使得NOx净化催化剂再生。
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10.发明授权Catalyst for purification of exhaust gas, regeneration method for the catalyst, and apparatus and method for purification of exhaust gas using the catalyst 失效用于净化废气的催化剂，催化剂的再生方法，以及使用该催化剂净化废气的装置和方法公开(公告)号：US08105561B2
公开(公告)日：2012-01-31
申请号：US12225692
申请日：2006-12-01
申请人： Miho Hatanaka , Toshitaka Tanabe , Yasutaka Nagai , Toshio Yamamoto , Kazuhiko Dohmae , Nobuyuki Takagi , Masahide Miura , Yasuo Ikeda
发明人： Miho Hatanaka , Toshitaka Tanabe , Yasutaka Nagai , Toshio Yamamoto , Kazuhiko Dohmae , Nobuyuki Takagi , Masahide Miura , Yasuo Ikeda
CPC分类号： B01D53/945 , B01D2255/102 , B01J23/002 , B01J23/63 , B01J23/894 , B01J23/8946 , B01J23/96 , B01J35/006 , B01J35/0066 , B01J35/1014 , B01J37/0201 , B01J37/0205 , B01J37/0207 , B01J37/03 , B01J38/10 , B01J38/12 , B01J2523/00 , F01N3/2006 , F01N11/002 , F01N2550/02 , Y02T10/22 , Y02T10/47 , B01J2523/3706 , B01J2523/48 , B01J2523/3712 , B01J2523/3718 , B01J2523/36
摘要： A catalyst for purification of exhaust gas in which a noble metal is supported on a metal-oxide support wherein, in a oxidation atmosphere, the noble metal exists on the surface of the support in high oxidation state, and the noble metal binds with a cation of the support via an oxygen atom on the surface of the support to form a surface oxide layer and, in a reduction atmosphere, the noble metal exists on the surface of the support in a metal state, and an amount of noble metal exposed at the surface of the support, measured by CO chemisorption, is 10% or more in atomic ratio to a whole amount of the noble metal supported on the support.
摘要翻译： 一种用于净化废气的催化剂，其中贵金属负载在金属氧化物载体上，其中在氧化气氛中贵金属以高氧化态存在于载体的表面上，贵金属与阳离子结合 的载体上的氧原子形成表面氧化物层，并且在还原气氛中，贵金属以金属状态存在于载体的表面上，并且贵金属的量在 通过CO化学吸附测定的载体表面与支撑在载体上的贵金属的全部量的原子比为10％以上。
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