公开(公告)号：US4339590A

公开(公告)日：1982-07-13

申请号：US226834

申请日：1981-01-21

申请人： Noboru Yamazaki ,  Seiichi Nakahama ,  Kazuo Yamaguchi

发明人： Noboru Yamazaki ,  Seiichi Nakahama ,  Kazuo Yamaguchi

IPC分类号： C07D327/06 ,  C07D327/00 ,  C07D341/00

CPC分类号： C07D327/00

摘要： A cyclic sulfur compound represented by the formula, ##STR1## wherein R is --CH.sub.2 CH.sub.2 O).sub.n CH.sub.2 CH.sub.2 --, m is an integer of 2 to 4 and n is an integer of 1 to 3 is novel and can be used as a crosslinking agent instead of sulfur per se and also as a monomer for preparing polysulfide polymer. Said cyclic sulfur compound can be produced by reacting a metal sulfide represented by the formula, ##STR2## wherein R is the same as defined above, R' and R" are independently selected from alkyl groups and aryl groups and M is silicon or tin, with a halogen, sulfur dichloride or sulfur monochloride.

摘要翻译： 由下式表示的环状硫化合物，其中R为-CH 2 CH 2 O，n为CH 2 CH 2 - ，m为2〜4的整数，n为1〜3的整数，可以作为交联剂代替 的硫本身以及作为制备多硫化物聚合物的单体。 所述环状硫化合物可以通过使由式表示的金属硫化物，其中R与上述定义相同，R'和R“独立地选自烷基和芳基，M是硅或锡 与卤素，二氯化硫或一氯化硫。

公开(公告)号：US08726162B2

公开(公告)日：2014-05-13

申请号：US12837812

申请日：2010-07-16

申请人： Takeru Mishima ,  Noboru Yamazaki

发明人： Takeru Mishima ,  Noboru Yamazaki

IPC分类号： G06F13/00

CPC分类号： G06F17/30749 ,  G06F17/30775

摘要： An audio apparatus contains a plurality of playable files stored in a database and organized in folders. The folders can be listed in a manner understandable at a glance even when viewed on a small display area and when the hierarchical structure shows a minimum level of detail. A folder selection section selects a folder from a database, and a directly-under-folder detection section detects if a playable file exists directly under a folder selected. A folder-under-folder detection section detects if a playable file exists directly under any folder located under the selected folder assuming no playable file exists directly under the selected folder.

摘要翻译： 音频装置包含存储在数据库中并被组织在文件夹中的多个可播放文件。 即使在小显示区域上观看时，以及当层次结构显示最小细节时，文件夹也可以一目了然的方式列出。 文件夹选择部分从数据库中选择一个文件夹，并且直接在文件夹下的检测部分检测可直接存在于所选文件夹之下的可播放文件。 文件夹下文件夹检测部分，假定在所选择的文件夹下没有直接存在可播放文件，则检测是否可以直接存在于所选文件夹下的任何文件夹下的可播放文件。

公开(公告)号：US20100222506A1

公开(公告)日：2010-09-02

申请号：US12160958

申请日：2007-11-22

申请人： Osamu Ohama ,  Noboru Yamazaki

发明人： Osamu Ohama ,  Noboru Yamazaki

IPC分类号： C08L67/00 ,  H01L21/673 ,  B29C45/00 ,  B65D85/86

CPC分类号： H01L21/67353 ,  B29C45/0001 ,  B29K2067/006 ,  H01L21/67366

摘要： A high-quality member installed in a wafer storage case is provided in which the wafer is not contaminated by the generated sulfur gas and the injection molding process is satisfactorily carried out.A member 1 installed in a case 2 for storing a wafer 3 is formed by injection molding a polybutylene terephthalate (PBT) resin. The PBT resin has a weight-average molecular weight (Mw) of 15000 to 20000. The member 1 installed in the wafer storage case is formed by injection molding so that the weight of sulfur in a sulfur-containing secondary antioxidant added to the PBT resin is 0.1% or less of the weight of the PBT resin.

摘要翻译： 提供了安装在晶片储存盒中的高质量构件，其中晶片不被所产生的硫气污染，并且令人满意地进行注射成型工艺。 通过注塑成型聚对苯二甲酸丁二醇酯（PBT）树脂形成安装在用于存储晶片3的壳体2中的构件1。 PBT树脂的重均分子量（Mw）为15000〜20000。通过注射成型形成安装在晶片储存盒中的构件1，使得添加到PBT树脂中的含硫次级抗氧化剂中的硫的重量 为PBT树脂重量的0.1％以下。

公开(公告)号：US20090169610A1

公开(公告)日：2009-07-02

申请号：US12223517

申请日：2007-02-02

申请人： Noboru Yamazaki ,  Sei Yoshida ,  Masuo Yamaoka ,  Akira Hori ,  Shigeya Kakimoto ,  Shuichi Furuya

发明人： Noboru Yamazaki ,  Sei Yoshida ,  Masuo Yamaoka ,  Akira Hori ,  Shigeya Kakimoto ,  Shuichi Furuya

IPC分类号： A61K9/127 ,  A61K39/395

CPC分类号： A61K9/1271 ,  A61K9/1272 ,  A61K31/282 ,  A61K31/337 ,  A61K31/513 ,  A61K31/537 ,  A61K31/573 ,  A61K31/7068 ,  A61K47/6911

摘要： The present invention provides cancer treatment preparations of excellent targetability. The sugar chain-modified liposomes of the present invention, which contain an aromatase inhibitor, anti-androgenic agent, lyase inhibitor, GnRH agonist, GnRH antagonist, anti-angiogenic agent, tyrosine kinase inhibitor, serine-threonine kinase inhibitor, antibody having an anticancer activity, ansamitocin, capecitabine, celmoleukin, docetaxel hydrate, gemcitabine hydrochloride, oxaliplatin, prednisolone, tegafur-uracil mixtures, zinostatin stimalamer or arsenic trioxide may be used as cancer treatment preparations having an excellent targetability.

摘要翻译： 本发明提供了具有优异目标性的癌症治疗制剂。 含有芳香酶抑制剂，抗雄激素剂，裂解酶抑制剂，GnRH激动剂，GnRH拮抗剂，抗血管生成剂，酪氨酸激酶抑制剂，丝氨酸 - 苏氨酸激酶抑制剂，抗癌剂的本发明糖链修饰脂质体 活性，安曲霉素，卡培他滨，纤维白蛋白，多西紫杉醇水合物，盐酸吉西他滨，奥沙利铂，泼尼松龙，替加氟 - 尿嘧啶混合物，维生素D抑制素或三氧化二砷可用作具有优异靶向性的癌症治疗制剂。

公开(公告)号：US06528159B1

公开(公告)日：2003-03-04

申请号：US09623276

申请日：2000-09-01

申请人： Yasuyuki Kanada ,  Yoshihiro Kuroda ,  Noboru Yamazaki ,  Yasunobu Ogata ,  Kunihiro Tomita ,  Tetsuo Nakai ,  Makoto Abe

发明人： Yasuyuki Kanada ,  Yoshihiro Kuroda ,  Noboru Yamazaki ,  Yasunobu Ogata ,  Kunihiro Tomita ,  Tetsuo Nakai ,  Makoto Abe

IPC分类号： B32B900

CPC分类号： C04B41/009 ,  B22F2998/00 ,  C04B41/4961 ,  C04B41/5035 ,  C04B41/5059 ,  C04B41/5066 ,  C04B41/5096 ,  C04B41/52 ,  C04B41/5353 ,  C04B41/84 ,  C04B41/85 ,  C04B41/87 ,  C04B41/89 ,  C04B41/91 ,  C22C26/00 ,  C22C2204/00 ,  C23C30/005 ,  Y10T428/24975 ,  Y10T428/265 ,  Y10T428/30 ,  Y10T428/31678 ,  C04B41/4521 ,  C04B41/4545 ,  C04B41/4531 ,  C04B35/52 ,  B22F2207/03

摘要： A diamond sintered body tool (20) having superior adhesion resistance, chipping resistance and high strength includes a tool base material (22) including a diamond sintered body, and a surface layer (21) formed on a surface of the tool base material (22). The surface layer (21) includes at least one of silicon, a silicon oxide, a silicon carbide, a silicon nitride and a solid solution thereof. The tool base material (22) has an inner portion (22b) including a first content of an iron group metal, and a surface portion (22a) surrounding the inner portion (22b ) and including a second content of the iron group metal lower than the first content.

摘要翻译： 具有优异的耐粘附性，耐崩裂性和高强度的金刚石烧结体工具（20）包括：工具基材（22），其包括金刚石烧结体，以及在工具基材（22）的表面上形成的表面层 ）。 表面层（21）包括硅，氧化硅，碳化硅，氮化硅及其固溶体中的至少一种。 工具基材（22）具有包含铁族金属的第一含量的内部部分（22b）和围绕内部部分（22b）的表面部分（22a），并且包含铁族金属的第二含量低于 第一个内容。

公开(公告)号：US5378700A

公开(公告)日：1995-01-03

申请号：US839769

申请日：1992-06-09

申请人： Yasuji Sakuma ,  Masaichi Hasegawa ,  Kenichiro Kataoka ,  Kenji Hoshina ,  Noboru Yamazaki ,  Takashi Kadota ,  Hisao Yamaguchi

发明人： Yasuji Sakuma ,  Masaichi Hasegawa ,  Kenichiro Kataoka ,  Kenji Hoshina ,  Noboru Yamazaki ,  Takashi Kadota ,  Hisao Yamaguchi

IPC分类号： A61K31/505 ,  A61K31/535 ,  A61K31/54 ,  A61K31/55 ,  C07D471/04 ,  C07D487/04

CPC分类号： C07D471/04 ,  C07D487/04

摘要： Disclosed is a fused pyrimidine of the formula [I] ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are as defined in the specification, Y represents a linking group of the formula ##STR2## wherein n is an integer of from 4 to 6, ##STR3## wherein A is a hydrogen atom or alkyl group; and Z represents a hydrogen atom, or other substituents; or Y and Z together represent an unsubstituted or substituted alkyl, alkenyl or arylalkyl group; or a 5- to 7-member heterocyclic ring which has a nitrogen atom, and further, an oxygen or sulfur atom as a hetero atom other than the nitrogen atom, being bonded via the nitrogen atom therein to the 4-position of the pyrimidine ring of the formula (I), a 5- to 7-member unsaturated heterocyclic ring which has 1 to 3 nitrogen atoms being bonded via the nitrogen atom therein to the 4-position of the pyrimidine ring of the formula (I), or a fused biheterocyclic ring constructed with 5- or 6-membered aromatic or non-aromatic rings, which has 1 to 3 nitrogen atoms in any position, being bonded via the nitrogen atom therein to the 4-position of the pyrimidine ring of the formula (I); andm is an integer of from 1 to 3;and a pharmaceutically acceptable acid addition salt thereof, as well as a process for producing same and a pharmaceutical preparation useful for a treatment of hypoxemia associated with respiratory diseases.

摘要翻译： PCT No.PCT / JP90 / 01313 Sec。 371日期：1992年6月9日 102（e）日期1992年6月9日PCT提交1990年10月11日PCT公布。 出版物WO91 / 05784 日期：1991年5月2日。公开是式[I]的融合嘧啶其中R 1，R 2和R 3如说明书中所定义，Y表示式的连接基团，其中n 是4至6的整数，其中A是氢原子或烷基; O（S） Z表示氢原子或其它取代基; 或Y和Z一起表示未取代或取代的烷基，烯基或芳基烷基; 或具有氮原子的5-至7-元杂环，以及作为氮原子以外的杂原子的氧或硫原子通过氮原子键合到嘧啶环的4-位上 式（I）的通式（I）中的氮原子数为1〜3的5〜7元不饱和杂环与式（I）的嘧啶环的4-位连接， 在其中具有1至3个氮原子的5-或6-元芳族或非芳族环经由其中的氮原子键合到式（I）的嘧啶环的4-位上构成的双杂环， ; m为1〜3的整数， 和其药学上可接受的酸加成盐，以及其制备方法和用于治疗与呼吸系统疾病相关的低氧血症的药物制剂。

公开(公告)号：US08301373B2

公开(公告)日：2012-10-30

申请号：US11941413

申请日：2007-11-16

申请人： Noboru Yamazaki

发明人： Noboru Yamazaki

IPC分类号： G01C21/00

CPC分类号： G01C21/26

摘要： The invention provides a navigation device and a facility image display method, whereby a user can recognize various types of information about a facility from the image corresponding to the facility. The navigation device includes road information, etc., used for drawing map images; facility information including the nodes of the facilities and a plurality of attributes of the facilities; a buffer memory that stores data of icon images corresponding to each of the plurality of attributes of the facilities; a map drawing unit that draws a map image on the basis of the road information, etc., and draws any of the icon images corresponding to the plurality of attributes of the facilities contained in the facility information, at a position in the map image corresponding to the node identified in the facility information; and an image synthesizing unit that causes a display unit to display the drawn image.

摘要翻译： 本发明提供一种导航装置和设施图像显示方法，由此用户可以从对应于设施的图像识别关于设施的各种类型的信息。 导航装置包括用于绘制地图图像的道路信息等; 设施信息，包括设施的节点和设施的多个属性; 缓冲存储器，其存储与所述设施的所述多个属性中的每一个对应的图标图像的数据; 地图绘制单元，其基于道路信息等绘制地图图像，并且在地图图像对应的位置处绘制与设施信息中包含的设施的多个属性对应的任何图标图像 到设施信息中识别的节点; 以及使显示单元显示绘制图像的图像合成单元。

公开(公告)号：US20090198443A1

公开(公告)日：2009-08-06

申请号：US12361862

申请日：2009-01-29

申请人： Noboru Yamazaki

发明人： Noboru Yamazaki

IPC分类号： G01C21/36

CPC分类号： G01C21/3605 ,  G01C21/3685

摘要： An in-vehicle navigation device includes a display unit, a storage unit which stores detailed map data of a shopping mall, a position detection unit which detects the current position of a vehicle, and a control unit which, when the destination is set to a facility in the shopping mall, detects a parking section close to the facility as a recommended parking section, and which, when the vehicle is determined to have entered and left the recommended parking section, provides, via the display unit, guidance advising the return of the vehicle to the recommended parking section. When the vehicle is determined to have entered the shopping mall, the control unit may display a detailed map of the shopping mall on a display screen of the display unit, and may display the recommended parking section in a different manner from the manner in which the other parking sections are displayed.

摘要翻译： 车载导航装置包括显示单元，存储商场的详细地图数据的存储单元，检测车辆的当前位置的位置检测单元，以及当将目的地设定为 在购物中心的设施中，作为推荐的停车部分检测靠近设施的停车部分，并且当车辆被确定已经进入并离开推荐的停车部分时，通过显示单元提供建议返回的指导 车辆到推荐的停车场。 当车辆被确定进入商场时，控制单元可以在显示单元的显示屏幕上显示商场的详细地图，并且可以以与以下方式不同的方式显示推荐的停车区段： 显示其他停车场。

公开(公告)号：US20090022426A1

公开(公告)日：2009-01-22

申请号：US12166009

申请日：2008-07-01

申请人： Noboru Yamazaki

发明人： Noboru Yamazaki

IPC分类号： G06K9/32

CPC分类号： G06K9/3283 ,  G01C21/3673 ,  G06K9/20 ,  G06K9/32 ,  G06K9/3208 ,  G06K9/3258 ,  G06K2209/01 ,  G06T11/203 ,  G09G5/227 ,  G09G5/24 ,  G09G2340/0414 ,  G09G2340/0421 ,  G09G2340/0464 ,  G09G2340/0492

摘要： A device includes a character-data rotating section that rotates a regular-position character by a predetermined angle with respect to a reference point that is the center point of the background area of the regular-position character by using regular-position character data having a rotation angle of 0° and a center-point matching processing section that horizontally and/or vertically enlarges the background area of the rotated character data to cause the center point of the rotated character and the center point of BMP data to match each other even with respect to rotated character data. Thus, when multiple pieces of character data are arranged so that the center points thereof lie on a reference line, not only are the center points of the characters aligned along the reference line, but also bottom portions of the characters aligned with respect to the reference line.

摘要翻译： 一种装置包括字符数据旋转部，通过使用具有正常位置字符数据的常规位置字符数据，使正常位置字符相对于作为正常位置字符的背景区域的中心点的参考点旋转预定角度 旋转角度为0°的中心点和中心点匹配处理部分，其水平和/或垂直放大旋转角色数据的背景区域，以使得旋转角色的中心点和BMP数据的中心点即使用 尊重旋转字符数据。 因此，当多个字符数据被布置为使得其中心点位于参考线上时，不仅字符的中心点沿着参考线排列，而且字符的中心点也相对于参考线排列 线。

公开(公告)号：US07070801B2

公开(公告)日：2006-07-04

申请号：US10352914

申请日：2003-01-29

申请人： Noboru Yamazaki ,  Shuji Kojima

发明人： Noboru Yamazaki ,  Shuji Kojima

IPC分类号： A61K9/127

CPC分类号： A61K8/14 ,  A61K9/1271 ,  A61K9/1272 ,  A61K47/549 ,  A61K47/62 ,  A61K47/6911 ,  A61Q19/00 ,  Y10T428/2984

摘要： The present invention provides a sugar-modified liposome having a sugar chain bonded to its membrane surface, preferably through a linker protein, and having excellent absorption qualities, particularly in the intestine. The molecular structure and quantity of the sugar chain is selectively varied to allow the liposome to be delivered in a targeted manner to selected cells and tissues. The liposome is applicable to medicinal drugs, cosmetics and other various products in the medical/pharmaceutical fields, and it is especially useful in a therapeutic drug delivery system that recognizes target cells and tissues, such as cancer cells, and in the delivery of drugs or genes locally to a selected region, or in a diagnostic cell/tissue sensing probe.