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23 条记录 (耗时 0.026 秒)

    Process for producing epoxycyclododecadiene
    6.
    发明授权
    Process for producing epoxycyclododecadiene 失效
    环氧环十二烷生产方法

    公开(公告)号：US06172243B2

    公开(公告)日：2001-01-09

    申请号：US09523392

    申请日：2000-03-10

    申请人： Nobuyuki Kuroda ,  Mitsuo Yamanaka ,  Hirofumi Takemoto ,  Kohei Ninomiya ,  Junichi Kugimoto

    发明人： Nobuyuki Kuroda ,  Mitsuo Yamanaka ,  Hirofumi Takemoto ,  Kohei Ninomiya ,  Junichi Kugimoto

    IPC分类号： C07D30112

    CPC分类号： C07D301/16 ,  C07D303/04

    摘要： Described is a process for producing 1,2-epoxy-5,9-cyclododecadiene, which comprises bringing 1,5,9-cyclododecatriene into contact with hydrogen peroxide in the presence of a carboxylic acid having an acid dissociation constant K at 25° C. of 5.0×10−6≦K≦1.0×10−4. The present invention makes it possible to provide an industrially desirable process which permits the production of 1,2-epoxy-5,9-cyclododecadiene with good selectivity and facilitates control of reaction including shortening of the reaction time.

    摘要翻译： 描述了一种生产1,2-环氧-5,9-环十二碳烯的方法，其包括在25℃下酸解离常数K的羧酸存在下使1,5,9-环十二碳三烯与过氧化氢接触 5.0×10-6 <= K <= 1.0×10 -4。 本发明使得可以提供工业上期望的方法，其允许以良好的选择性生产1,2-环氧-5,9-环十二烷，并且有助于控制反应，包括缩短反应时间。

    Process for producing 1,2-epoxy-5,9-cyclododecadiene
    7.
    发明授权
    Process for producing 1,2-epoxy-5,9-cyclododecadiene 有权
    1,2-环氧-5,9-环十二烯的生产方法

    公开(公告)号：US6043383A

    公开(公告)日：2000-03-28

    申请号：US290500

    申请日：1999-04-12

    申请人： Nobuyuki Kuroda ,  Mitsuo Yamanaka ,  Osamu Yamazaki ,  Hirofumi Takemoto ,  Kohei Ninomiya ,  Junichi Kugimoto ,  Koji Kaiso ,  Hideo Shimomura

    发明人： Nobuyuki Kuroda ,  Mitsuo Yamanaka ,  Osamu Yamazaki ,  Hirofumi Takemoto ,  Kohei Ninomiya ,  Junichi Kugimoto ,  Koji Kaiso ,  Hideo Shimomura

    IPC分类号： C07D303/04 ,  C07D303/06 ,  C07D301/12 ,  C07D301/16

    CPC分类号： C07D303/04

    摘要： 1,2-epoxy-5,9-cyclododecadiene is produced with a high selectivity thereto by epoxidizing 1,5,9-cyclododecatriene in a continuous multi-stage oxidation apparatus having a plurality of reactors connected to each other in series in such a manner that (1) in a first reactor, 1,5,9-cyclododecatriene, hydrogen peroxide, catalyst components and optionally a mineral acid are subjected to an epoxidation reaction; (2) the resultant reaction mixture delivered from the first reactor is passed through one or more succeeding reactors to further epoxidize the non-reacted 1,5,9-cyclododecatriene with the non-reacted hydrogen peroxide; and (3) the final reaction mixture produced in a rearend reactor is delivered from the oxidation apparatus, and optionally subjected to an isolation-refining procedure wherein the target 1,2-epoxy-5,9-cyclododecadiene is refined and collected and the non-reacted 1,5,9-cyclododecatriene is recovered and recycled to the epoxidation procedure.

    摘要翻译： 通过在连续的多级氧化装置中环氧化1,5,9-环十二碳三烯以高选择性制备1,2-环氧-5,9-环十二烯，其中多个反应器以这种方式相互串联连接 （1）在第一反应器，1,5,9-环十二碳三烯，过氧化氢，催化剂组分和任选的无机酸中进行环氧化反应; （2）将从第一反应器输送的所得反应混合物通过一个或多个后续反应器，以用未反应的过氧化氢进一步环氧化未反应的1,5,9-环十二碳三烯; 和（3）在再循环反应器中产生的最终反应混合物从氧化装置输送，并任选地进行分离精制程序，其中精制和收集目标1,2-环氧-5,9-环十二烷二烯， - 回收的1,5,9-环十二碳三烯被回收并再循环至环氧化方法。

    Process for producing laurolactam
    8.
    发明授权
    Process for producing laurolactam 有权
    生产月桂内酰胺的方法

    公开(公告)号：US08309714B2

    公开(公告)日：2012-11-13

    申请号：US12744675

    申请日：2008-11-19

    申请人： Junichi Kugimoto ,  Joji Kawai ,  Hideo Shimomura ,  Ryouta Yasumatsu ,  Nobuhiro Ii

    发明人： Junichi Kugimoto ,  Joji Kawai ,  Hideo Shimomura ,  Ryouta Yasumatsu ,  Nobuhiro Ii

    IPC分类号： C07D201/04 ,  C07D225/02

    CPC分类号： C07D201/04 ,  C07D225/02 ,  Y02P20/582

    摘要： Provided is a process for efficiently producing laurolactam by simple steps from cyclododecanone and hydroxylamine. This production process comprises the steps of: (a) reacting cyclododecanone with hydroxylamine in an aqueous solution in the presence of an oxime-formation solvent to produce cyclododecanone oxime; (b) separating the reaction mixture obtained after the oxime-forming step into an oil and an aqueous phases and collecting a solution of cyclododecanone oxime of the oil phase; (c) removing a part or all of the oxime-formation solvent and dissolved water from the solution of cyclododecanone oxime which is collected as an oil phase in the oil/aqueous phase separation step, whereby preparing a solution containing a rearrangement solvent to be used in a rearrangement reaction in a later step and the cyclododecanone oxime; (d) producing laurolactam from cyclododecanone oxime by rearrangement reaction using an aromatic-ring containing compound as a rearrangement catalyst; and (e) separating and removing the rearrangement solvent and the rearrangement catalyst from the reaction mixture after the rearrangement step, and purifying the laurolactam.

    摘要翻译： 提供一种通过简单的步骤从环十二酮和羟胺有效地生产十二内酰胺的方法。 该制备方法包括以下步骤：（a）在肟形成溶剂存在下，使环十二酮与羟胺在水溶液中反应，生成环十二烷酮肟; （b）将在肟形成步骤后获得的反应混合物分离成油相和水相，并收集油相的环十二烷酮肟溶液; （c）从油/水相分离步骤中以油相收集的环十二烷酮肟溶液中除去部分或全部肟形成溶剂和溶解的水，由此制备含有使用的重排溶剂的溶液 在后续步骤中的重排反应和环十二酮肟; （d）使用含芳环的化合物作为重排催化剂，通过重排反应从环十二酮肟生产月桂内酰胺; 和（e）在重排步骤之后从反应混合物中分离和除去重排溶剂和重排催化剂，并纯化月桂内酰胺。

    PROCESS FOR PRODUCING LAUROLACTAM
    10.
    发明申请
    PROCESS FOR PRODUCING LAUROLACTAM 有权
    生产乳酸菌的方法

    公开(公告)号：US20100267944A1

    公开(公告)日：2010-10-21

    申请号：US12744675

    申请日：2008-11-19

    申请人： Junichi Kugimoto ,  Joji Kawai ,  Hideo Shimomura ,  Ryouta Yasumatsu ,  Nobuhiro II

    发明人： Junichi Kugimoto ,  Joji Kawai ,  Hideo Shimomura ,  Ryouta Yasumatsu ,  Nobuhiro II

    IPC分类号： C07D225/02

    CPC分类号： C07D201/04 ,  C07D225/02 ,  Y02P20/582

    摘要： Provided is a process for efficiently producing laurolactam by simple steps from cyclododecanone and hydroxylamine. This production process comprises the steps of: (a) reacting cyclododecanone with hydroxylamine in an aqueous solution in the presence of an oxime-formation solvent to produce cyclododecanone oxime; (b) separating the reaction mixture obtained after the oxime-forming step into an oil and an aqueous phases and collecting a solution of cyclododecanone oxime of the oil phase; (c) removing a part or all of the oxime-formation solvent and dissolved water from the solution of cyclododecanone oxime which is collected as an oil phase in the oil/aqueous phase separation step, whereby preparing a solution containing a rearrangement solvent to be used in a rearrangement reaction in a later step and the cyclododecanone oxime; (d) producing laurolactam from cyclododecanone oxime by rearrangement reaction using an aromatic-ring containing compound as a rearrangement catalyst; and (e) separating and removing the rearrangement solvent and the rearrangement catalyst from the reaction mixture after the rearrangement step, and purifying the laurolactam.

    摘要翻译： 提供一种通过简单的步骤从环十二酮和羟胺有效地生产十二内酰胺的方法。 该制备方法包括以下步骤：（a）在肟形成溶剂存在下，使环十二酮与羟胺在水溶液中反应，生成环十二酮肟; （b）将在肟形成步骤后获得的反应混合物分离成油相和水相，并收集油相的环十二烷酮肟溶液; （c）从油/水相分离步骤中以油相收集的环十二酮肟溶液中除去部分或全部肟形成溶剂和溶解的水，由此制备含有使用的重排溶剂的溶液 在后续步骤中的重排反应和环十二酮肟; （d）使用含芳环的化合物作为重排催化剂，通过重排反应从环十二酮肟生产月桂内酰胺; 和（e）在重排步骤之后从反应混合物中分离和除去重排溶剂和重排催化剂，并纯化月桂内酰胺。