公开(公告)号：US20060154337A1

公开(公告)日：2006-07-13

申请号：US11313169

申请日：2005-12-20

申请人： Nobuyuki Sato ,  Masahiko Shimada ,  Hiroshi Oda

发明人： Nobuyuki Sato ,  Masahiko Shimada ,  Hiroshi Oda

IPC分类号： C12N9/24 ,  C07H21/04 ,  C12P21/06

CPC分类号： C12Y402/02004 ,  A61K38/00 ,  C12N9/88 ,  G01N33/573

摘要： Nucleic acid sequences coding for the chondroitinase ABC gene and isolated chondroitinase ABC protein produced in a host cell transformed with a nucleic acid vector directing the expression of a nucleotide sequence coding for chondroitinase ABC protein are described. Chondroitinase ABC prepared by chemical synthesis is also described. Monoclonal and polyclonal antibodies which are specifically reactive with chondroitinase ABC protein are disclosed. The isolated chondroitinase ABC can be used in methods of treating intervertebral disc displacement, promoting neurite regeneration, and detecting galactosaminoglycans.

摘要翻译： 描述了编码软骨素酶ABC基因的核酸序列和在用指导编码软骨素酶ABC蛋白的核苷酸序列的表达的核酸载体转化的宿主细胞中产生的分离的软骨素酶ABC蛋白。 还描述了通过化学合成制备的软骨素酶ABC。 公开了与软骨素酶ABC蛋白特异性反应的单克隆和多克隆抗体。 分离的软骨素酶ABC可用于治疗椎间盘置换，促进神经突再生和检测半乳糖胺聚糖的方法。

公开(公告)号：USRE43166E1

公开(公告)日：2012-02-07

申请号：US12613119

申请日：2009-11-05

申请人： Nobuyuki Sato ,  Masahiko Shimada ,  Hiroshi Oda

发明人： Nobuyuki Sato ,  Masahiko Shimada ,  Hiroshi Oda

IPC分类号： C12N15/60 ,  C12N15/63 ,  C12N5/10 ,  C12N1/00 ,  C12N1/21 ,  C12N9/88

CPC分类号： C12Y402/02004 ,  C12N9/88

摘要： Nucleic acid sequences coding for the chondroitinase ABC gene and isolated chondroitinase ABE protein produced in a host cell transformed with a nucleic acid vector directing the expression of a nucleotide sequence coding for chondroitinase ABE protein described. Chondroitinase ABC prepared by chemical synthesis also described. Monoclonal and polyclonal antibodies which are specifically reactive with chondroitinase ABC protein are disclosed. The isolated chondroitinase ABC can be used in methods of treating intervertebral disc replacement, promoting neurite regeneration, and detecting galactosaminoglycans.

摘要翻译： 编码软骨素酶ABC基因的核酸序列和分离的软骨素酶ABE蛋白质在用指导编码软骨素酶ABE蛋白质的核苷酸序列的表达的核酸载体转化的宿主细胞中产生。 通过化学合成制备的软骨素酶ABC也有描述。 公开了与软骨素酶ABC蛋白特异性反应的单克隆和多克隆抗体。 分离的软骨素酶ABC可用于治疗椎间盘置换，促进神经突再生和检测半乳糖胺聚糖的方法。

公开(公告)号：US07008783B1

公开(公告)日：2006-03-07

申请号：US08488960

申请日：1995-06-07

申请人： Nobuyuki Sato ,  Masahiko Shimada ,  Hiroshi Oda

发明人： Nobuyuki Sato ,  Masahiko Shimada ,  Hiroshi Oda

IPC分类号： C12N9/88 ,  C12N15/60 ,  C12N15/63 ,  C12N5/10 ,  C12N1/00 ,  C12N1/21

CPC分类号： C12Y402/02004 ,  C12N9/88

摘要： Nucleic acid sequences coding for the chondroitinase ABC gene and isolated chondroitinase ABE protein produced in a host cell transformed with a nucleic acid vector directing the expression of a nucleotide sequence coding for chondroitinase ABE protein described. Chondroitinase ABC prepared by chemical synthesis also described. Monoclonal and polyclonal antibodies which are specifically reactive with chondroitinase ABC protein are disclosed. The isolated chondroitinase ABC can be used in methods of treating intervertebral disc replacement, promoting neurite regeneration, and detecting galactosaminoglycans.

摘要翻译： 编码软骨素酶ABC基因的核酸序列和分离的软骨素酶ABE蛋白质在用指导编码软骨素酶ABE蛋白质的核苷酸序列的表达的核酸载体转化的宿主细胞中产生。 通过化学合成制备的软骨素酶ABC也有描述。 公开了与软骨素酶ABC蛋白特异性反应的单克隆和多克隆抗体。 分离的软骨素酶ABC可用于治疗椎间盘置换，促进神经突再生和检测半乳糖胺聚糖的方法。

公开(公告)号：US09507258B2

公开(公告)日：2016-11-29

申请号：US13290558

申请日：2011-11-07

申请人： Koji Ichikawa ,  Masahiko Shimada ,  Takashi Nishimura

发明人： Koji Ichikawa ,  Masahiko Shimada ,  Takashi Nishimura

IPC分类号： G03F7/004 ,  C08F220/38 ,  G03F7/039 ,  G03F7/20 ,  C08F220/28

CPC分类号： G03F7/004 ,  C08F220/28 ,  C08F220/38 ,  G03F7/0045 ,  G03F7/0392 ,  G03F7/0397 ,  G03F7/2041

摘要： The present invention provides a resin comprising a structural unit represented by the formula (aa): wherein T1 represents a C4-C34 sultone ring group optionally having one or more substituents, X1 represents —O— or —N(Rc)—, Rc represents a hydrogen atom or a C1-C6 alkyl group, Z1 represents *-X2—, *-X2—X4—CO—X3—, or *-X2—CO—X4—X3—, X2 and X3 independently each represent a C1-C6 alkanediyl group, X4 represents —O— or —N(Rc)—, * represents a binding position to X1, and R1 represents a C1-C6 alkyl group optionally having one or more halogen atoms, a hydrogen atom or a halogen atom.

公开(公告)号：US09221391B2

公开(公告)日：2015-12-29

申请号：US14344090

申请日：2012-07-09

申请人： Masahiko Shimada ,  Masatsugu Urakawa

发明人： Masahiko Shimada ,  Masatsugu Urakawa

IPC分类号： B60Q1/40 ,  B60Q1/42 ,  B60Q1/00 ,  H01H3/42

CPC分类号： B60Q1/42 ,  B60Q1/0076 ,  B60Q1/425 ,  H01H3/42

摘要： A vehicle turn signal switch device whereby the production of knocking sounds by a cancellation pin when a steering wheel is turned in the direction of a turn signal is suppressed. A turn signal switch includes a fixed member and a movable plate. The cancellation pin, which is supported by the fixed member and the movable plate such that the cancellation pin can swing and move forward and backward relative to a cancellation cam, includes a sliding-contact surface that is in sliding contact with the fixed member. The cancellation pin is biased by a return spring in the direction of the cancellation cam and in the direction of the sliding contact of the sliding-contact surface with the fixed member.

摘要翻译： 一种车辆转向信号开关装置，其中当方向盘沿转向信号的方向转动时，由消除销产生爆震声音被抑制。 转向信号开关包括固定部件和可动板。 由固定构件和可动板支撑的抵销销相对于取消凸轮可以摆动并向前和向后移动，包括与固定构件滑动接触的滑动接触表面。 消除销通过复位弹簧沿着取消凸轮的方向和滑动接触表面与固定构件的滑动接触的方向偏置。

公开(公告)号：US20140044970A1

公开(公告)日：2014-02-13

申请号：US14057690

申请日：2013-10-18

申请人： Seiji Sarayama ,  Masahiko Shimada ,  Hisanori Yamane ,  Hirokazu Iwata

发明人： Seiji Sarayama ,  Masahiko Shimada ,  Hisanori Yamane ,  Hirokazu Iwata

IPC分类号： C09K11/62 ,  C30B29/40

CPC分类号： C30B7/105 ,  C09K11/62 ,  C30B7/00 ,  C30B9/00 ,  C30B11/00 ,  C30B15/00 ,  C30B29/403 ,  C30B29/406 ,  H01L29/2003 ,  H01L29/7783 ,  Y10T117/1092 ,  Y10T117/1096 ,  Y10T428/2982

摘要： A crystal has a diameter of 1 cm or more and shows a strongest peak in cathode luminescent spectrum at a wavelength of 360 nm in correspondence to a band edge.

摘要翻译： 晶体具有1cm或更大的直径，并且对应于带边缘，在360nm波长处的阴极发光光谱中显示出最强峰。

公开(公告)号：US08562737B2

公开(公告)日：2013-10-22

申请号：US12139230

申请日：2008-06-13

申请人： Seiji Sarayama ,  Masahiko Shimada ,  Hisanori Yamane ,  Masato Aoki

发明人： Seiji Sarayama ,  Masahiko Shimada ,  Hisanori Yamane ,  Masato Aoki

IPC分类号： C30B13/02

CPC分类号： C01B21/06 ,  C30B11/002 ,  C30B29/403 ,  C30B29/406

摘要： A crystal growth method, comprising the steps of: a) bringing a nitrogen material into a reaction vessel in which a mixed molten liquid comprising an alkaline metal and a group-III metal; and b) growing a crystal of a group-III nitride using the mixed molten liquid and the nitrogen material brought in by the step a) in the reaction vessel, wherein a provision is made such as to prevent a vapor of the alkaline metal from dispersing out of the reaction vessel.

摘要翻译： 一种晶体生长方法，包括以下步骤：a）将氮材料送入其中包含碱金属和III族金属的混合熔融液体的反应容器中; 以及b）使用混合的熔融液体和由步骤a）引入的氮材料在III族氮化物中生长晶体，其中设置如防止碱金属的蒸气分散 离开反应容器。

公开(公告)号：US20100035180A1

公开(公告)日：2010-02-11

申请号：US12536239

申请日：2009-08-05

申请人： Masahiko Shimada ,  Kazuhiko Hashimoto ,  Satoshi Yamaguchi ,  Soon Shin Kim ,  Yoshiyuki Takata ,  Takashi Hiraoka

发明人： Masahiko Shimada ,  Kazuhiko Hashimoto ,  Satoshi Yamaguchi ,  Soon Shin Kim ,  Yoshiyuki Takata ,  Takashi Hiraoka

IPC分类号： G03F7/004

CPC分类号： G03F7/0397 ,  G03F7/0045 ,  G03F7/0046 ,  Y10S430/108 ,  Y10S430/111

摘要： The present invention provides a chemically amplified positive composition comprising: a resin comprising a structural unit represented by the formula (I): wherein R1 represents a hydrogen atom, a halogen atom, a C1-C4 alkyl group or a C1-C4 perfluoroalkyl group, Z represents a single bond or —(CH2)k—CO—X4—, k represents an integer of 1 to 4, X1, X2, X3 and X4 each independently represents an oxygen atom or a sulfur atom, m represents an integer of 1 to 3 and n represents an integer of 0 to 3, and an acid generator.

摘要翻译： 本发明提供一种化学放大阳性组合物，其包含：包含由式（I）表示的结构单元的树脂：其中R1表示氢原子，卤素原子，C1-C4烷基或C1-C4全氟烷基， Z表示单键或 - （CH 2）k -CO-X 4 - ，k表示1〜4的整数，X 1，X 2，X 3，X 4各自独立地表示氧原子或硫原子，m表示1的整数 3，n表示0〜3的整数，酸产生剂。

公开(公告)号：US07261775B2

公开(公告)日：2007-08-28

申请号：US10765502

申请日：2004-01-28

申请人： Hirokazu Iwata ,  Seiji Sarayama ,  Hisanori Yamane ,  Masahiko Shimada ,  Masato Aoki

发明人： Hirokazu Iwata ,  Seiji Sarayama ,  Hisanori Yamane ,  Masahiko Shimada ,  Masato Aoki

IPC分类号： C30B11/04

CPC分类号： H01L29/7787 ,  C30B11/00 ,  C30B29/403 ,  C30B29/406 ,  H01L29/2003 ,  Y10T428/2982

摘要： A method of growing a group III nitride crystal grows a group III nitride crystal from a solution in which an alkaline metal, a group III metal and nitrogen are dissolved, and includes, in the solution, a material which increases solubility of the nitrogen into the solution.

摘要翻译： 生长III族氮化物晶体的方法从溶解有碱金属，III族金属和氮的溶液中生长III族氮化物晶体，并且在该溶液中包含增加氮的溶解度的材料 解。

公开(公告)号：US4447362A

公开(公告)日：1984-05-08

申请号：US831426

申请日：1977-09-08

申请人： Kiyoshi Watanabe ,  Satoshi Ideguchi ,  Masahiro Ogura ,  Masahiko Shimada ,  Hajime Kawaharada

发明人： Kiyoshi Watanabe ,  Satoshi Ideguchi ,  Masahiro Ogura ,  Masahiko Shimada ,  Hajime Kawaharada

IPC分类号： A61K31/12 ,  C12P7/66 ,  C07C46/10 ,  C07C50/06

CPC分类号： C12P7/66 ,  A61K31/12

摘要： A process is disclosed wherein coenzyme Q is prepared from tissues of animals and plants or microbial cells by treating a water suspension of said materials with an alkali, or with an acid and then an alkali, and by extracting the treated suspension with at least one water-immiscible organic solvent followed by recovery of coenzyme Q from the extract.

摘要翻译： 公开了一种方法，其中辅酶Q由动物和植物或微生物细胞的组织制备，通过用碱或用酸碱化处理所述材料的水悬浮液，并用至少一种水提取处理的悬浮液 可混溶的有机溶剂，然后从提取物中回收辅酶Q。