Peptides and therapeutic agent for autoimmune diseases containing the
same
    1.
    发明授权
    Peptides and therapeutic agent for autoimmune diseases containing the same 失效
    肽及其含有该自身免疫性疾病的治疗剂

    公开(公告)号:US6034064A

    公开(公告)日:2000-03-07

    申请号:US930741

    申请日:1998-01-08

    IPC分类号: A61K38/00 C07K7/06 A61K38/08

    CPC分类号: C07K7/06 A61K38/00

    摘要: The present invention relates to a peptide having the following amino acid sequence:Ala-Xaa1-Leu-Xaa2-Phe-Xaa3-Xaa4-Xaa5-(Xaa6)n(wherein Xaa1 and Xaa4 each independently represents an amino acid residue which may have an alkyl or heteroalkyl side chain which may be substituted by a hydroxy, amino or guanidyl group;Xaa2 and Xaa6 each independently represents an amino acid residue which may have an alkyl or heteroalkyl side chain which may be substituted by a hydroxyl group;Xaa3 and Xaa5 each independently represents an amino acid residue which may have a hydrophobic side chain; andn stands for 1 or 0), or derivatives thereof; and a modification thereof.The peptide or derivatives thereof according to the present invention is useful as a pharmaceutical composition for the prevention and treatment of autoimmune diseases, rejection reaction attendant on the organ transplantation, inflammation or the like.

    摘要翻译: PCT No.PCT / JP96 / 00917 Sec。 371日期1998年1月8日 102(e)日期1998年1月8日PCT提交1996年4月3日PCT公布。 出版物WO96 / 31529 日期:1996年10月10日本发明涉及具有以下氨基酸序列的肽:Ala-Xaa1-Leu-Xaa2-Phe-Xaa3-Xaa4-Xaa5-(Xaa6)n(其中Xaa1和Xaa4各自独立地表示氨基酸 可以具有可以被羟基,氨基或胍基取代的烷基或杂烷基侧链的残基; Xaa2和Xaa6各自独立地表示可以具有可被羟基取代的烷基或杂烷基侧链的氨基酸残基 ; Xaa3和Xaa5各自独立地表示可具有疏水性侧链的氨基酸残基,n表示1或0)或其衍生物; 及其修改。 根据本发明的肽或其衍生物可用作预防和治疗自身免疫疾病,伴随器官移植排斥反应,炎症等的药物组合物。

    Surge protection circuit in three-phase four-wire circuit
    2.
    发明授权
    Surge protection circuit in three-phase four-wire circuit 有权
    三相四线电路中的浪涌保护电路

    公开(公告)号:US09025297B2

    公开(公告)日:2015-05-05

    申请号:US13391870

    申请日:2010-08-17

    IPC分类号: H02H3/22 H02H9/04

    CPC分类号: H02H9/042

    摘要: In a surge protection circuit in a three-phase four-wire circuit, a first three-phase three-wire surge module includes terminals respectively coupled to a first phase R, a second phase S, a third phase T, and a fifth phase E. A single-phase two-wire surge module includes terminals respectively coupled to one phase R among the first phase R, the second phase S, and the third phase T, to a fourth phase N, and to the fifth phase E. The second three-phase three-wire surge module includes terminals respectively coupled to the two phases S and T among the first phase R, the second phase S, and the third phase T, to the fourth phase N, and to the fifth phase E. The two phases S and T are not coupled to the single-phase two-wire surge module.

    摘要翻译: 在三相四线电路中的浪涌保护电路中,第一三相三线浪涌模块包括分别耦合到第一相R,第二相S,第三相T和第五相E的端子 单相双线浪涌模块包括分别耦合到第一相R,第二相S和第三相T中的一相R到第四相N和第五相E的端子。第二相 三相三线浪涌模块包括分别耦合到第一相R,第二相S和第三相T,第四相N和第五相E中的两相S和T的端子。 两相S和T不耦合到单相二线浪涌模块。

    SURGE PROTECTION CIRCUIT IN THREE-PHASE FOUR-WIRE CIRCUIT
    3.
    发明申请
    SURGE PROTECTION CIRCUIT IN THREE-PHASE FOUR-WIRE CIRCUIT 有权
    三相四线电路中的保护电路

    公开(公告)号:US20120147512A1

    公开(公告)日:2012-06-14

    申请号:US13391870

    申请日:2010-08-17

    IPC分类号: H02H3/22

    CPC分类号: H02H9/042

    摘要: In a surge protection circuit in a three-phase four-wire circuit, a first three-phase three-wire surge module includes terminals respectively coupled to a first phase R, a second phase S, a third phase T, and a fifth phase E. A single-phase two-wire surge module includes terminals respectively coupled to one phase R among the first phase R, the second phase S, and the third phase T, to a fourth phase N, and to the fifth phase E. The second three-phase three-wire surge module includes terminals respectively coupled to the two phases S and T among the first phase R, the second phase S, and the third phase T, to the fourth phase N, and to the fifth phase E. The two phases S and T are not coupled to the single-phase two-wire surge module.

    摘要翻译: 在三相四线电路中的浪涌保护电路中,第一三相三线浪涌模块包括分别耦合到第一相R,第二相S,第三相T和第五相E的端子 单相双线浪涌模块包括分别耦合到第一相R,第二相S和第三相T中的一相R到第四相N和第五相E的端子。第二相 三相三线浪涌模块包括分别耦合到第一相R,第二相S和第三相T,第四相N和第五相E中的两相S和T的端子。 两相S和T不耦合到单相二线浪涌模块。

    Gas Engine System with Detection Function of Abnormality Occurrence of Gas Pressure Detection Mechanism
    5.
    发明申请
    Gas Engine System with Detection Function of Abnormality Occurrence of Gas Pressure Detection Mechanism 有权
    具有气体压力检测机构异常检测功能的气体发动机系统

    公开(公告)号:US20130327295A1

    公开(公告)日:2013-12-12

    申请号:US13979543

    申请日:2012-01-13

    IPC分类号: F02M69/00

    摘要: A gas engine system has a control unit including: a first determination section for determining, as a first determination, whether the gas pressure is a low pressure less than a predetermined pressure, while the control device recognizes the gas valve is closed; a second determination section for determining, as a second determination, whether the gas pressure is a high pressure equal to or more than the predetermined pressure, while the control device recognizes that the gas valve is open, if the first determination determines the gas pressure is the low pressure; a start-up section for performing the first and second determinations before start of engine operation when receiving a start-up command; and an operation start section for opening the valve and starting the engine, if the first determination determines the gas pressure is the low pressure, and if the second determination determines the pressure is the high pressure.

    摘要翻译: 燃气发动机系统具有控制单元,该控制单元包括:第一确定部,用于当控制装置识别出气阀关闭时,确定气体压力是否小于预定压力的低压,作为第一确定; 第二确定部分,用于当控制装置识别出气阀打开时,确定气体压力是否为等于或大于预定压力的高压,作为第二确定,如果第一确定确定气体压力为 低压; 启动部,用于在接收到启动命令时,在发动机运转开始之前执行第一和第二确定; 以及如果第一确定确定气体压力是低压,并且如果第二确定确定压力是高压,则操作开始部分用于打开阀并启动发动机。

    Resin sealing apparatus and resin sealing method
    6.
    发明授权
    Resin sealing apparatus and resin sealing method 失效
    树脂密封装置和树脂密封方法

    公开(公告)号:US08029720B2

    公开(公告)日:2011-10-04

    申请号:US12091159

    申请日:2006-11-17

    IPC分类号: B29C70/72 H01L21/56

    摘要: A resin molten in a pot portion 59 is molded by being loaded via a gate 48 into a cavity, which has a rectangular parallelepiped shape in plan view and is formed of both molds 1 and 2, which are a second mold 2 and a first mold 1 that can make or release contact with the second mold 2. The pot portion 59 is provided at either one of the molds 1 and 2 and constituted of recess portions 54c located at prescribed intervals at the cavity. The recess portions 54c have a bottom surface constituted of part of a moving member 60 movable toward an opening portion. The gate 48 is structured so that one side of the cavity and the long side of the pot portion 59 are connected with each other.

    摘要翻译: 在锅部分59中熔融的树脂通过门48装入空腔中,该空腔在平面图中具有长方体形状,并且由模具1和2形成,它们是第二模具2和第一模具 罐部分59设置在模具1和2中的任何一个上,并且由在凹腔处以规定间隔设置的凹部54c构成。 凹部54c具有由朝向开口部移动的移动部件60的一部分构成的底面。 门48的结构使得空腔的一侧和锅部分59的长边彼此连接。

    RESIN SEALING APPARATUS
    7.
    发明申请
    RESIN SEALING APPARATUS 有权
    树脂密封装置

    公开(公告)号:US20100247697A1

    公开(公告)日:2010-09-30

    申请号:US12438535

    申请日:2007-09-13

    IPC分类号: B29C33/30

    摘要: There are provided a first mold 2 and a second mold 1 that can be brought into and released from contact with the first mold 2. A substrate 70 provided in both the molds 1, 2 and mounted with electronic components is subjected to resin sealing and molding by filling with resin of cavities formed by both the molds 1, 2. The second mold 1 is placed on a base plate 9 so as to be capable of horizontally reciprocating, and has a cavity block 7 that can be brought into and released from contact with the first mold 2 and a mold clamping mechanism 16 that supports the cavity block 7 and that brings and releases the cavity block 7 into and from contact with the first mold 2 so as to perform mold clamping. On the base plate 9 is provided a horizontal actuation mechanism 11 for moving the second mold 1 to a facing position where the second mold 1 faces the first mold 2 and to a non-facing position where the second mold 1 has been moved sideways from the facing position.

    摘要翻译: 设置有第一模具2和第二模具1,该第一模具2和第二模具1可以与第一模具2接触并脱离接触。设置在两个模具1,2中并安装有电子部件的基板70经受树脂密封和模制 通过填充由两个模具1,2形成的空腔的树脂。第二模具1被放置在基板9上以便能够水平往复运动,并且具有可以被引入和释放的空腔模块7 第一模具2和模具夹持机构16,其支撑空腔模块7,并且使空腔模块7与第一模具2接触和脱离接触,从而进行模具夹紧。 在基板9上设置有水平致动机构11,用于将第二模具1移动到第二模具1面向第一模具2的面对位置和第二模具1已经从第二模具1侧向移动的非对置位置 面对位置

    OPTICAL TRANSMISSION/RECEPTION MODULE
    8.
    发明申请
    OPTICAL TRANSMISSION/RECEPTION MODULE 有权
    光传输/接收模块

    公开(公告)号:US20110311229A1

    公开(公告)日:2011-12-22

    申请号:US13203761

    申请日:2009-06-01

    IPC分类号: H04J14/02

    摘要: An optical transmission/reception module including a filter holder on which filter mount surfaces for mounting wavelength division multiplexing filters and light wavelength band limiting filters are formed and in which a hole for guiding a light signal is formed in each of the filter mount surfaces incorporated into a housing. The wavelength division multiplexing filters and the light wavelength band limiting filters are mounted to the filter mount surfaces formed on the filter holder, respectively.

    摘要翻译: 一种光发送/接收模块,包括滤光器保持器,其上形成有用于安装波分复用滤光器的滤光片安装表面和光波长带限制滤光器,并且其中在每个滤光器安装表面中形成用于引导光信号的孔, 一个住房。 波分复用滤波器和光波长带限制滤波器分别安装到形成在滤波器支架上的滤波器安装表面。

    Collision detection system
    10.
    发明授权
    Collision detection system 失效
    碰撞检测系统

    公开(公告)号:US5392024A

    公开(公告)日:1995-02-21

    申请号:US897750

    申请日:1992-06-12

    IPC分类号: B60R21/01 B60Q1/00

    CPC分类号: B60R21/0136

    摘要: A collision detection system utilizing a set of primary sensors and a secondary sensor. When a sufficient collision load is applied to the sensors, the sensors output a signal. The primary sensors are constructed to be more sensitive than the secondary sensor. Based on the outputs of the primary and secondary sensors, a control unit detects the collision. Upon detecting the collision, the control unit outputs a collision detection signal which activates a protection device, such as an air bag.

    摘要翻译: 利用一组主传感器和二次传感器的碰撞检测系统。 当传感器施加足够的碰撞载荷时,传感器输出信号。 主传感器被构造成比次传感器更敏感。 基于主传感器和次传感器的输出,控制单元检测到碰撞。 在检测到碰撞时,控制单元输出激活诸如安全气囊的保护装置的碰撞检测信号。