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    MULTI FUNCTION PERIPHERAL AND METHOD THERFOR
    1.
    发明申请
    MULTI FUNCTION PERIPHERAL AND METHOD THERFOR 有权
    多功能外设和方法

    公开(公告)号：US20090027721A1

    公开(公告)日：2009-01-29

    申请号：US12179041

    申请日：2008-07-24

    申请人： Noriko MISUMI ,  Ayako Sakai ,  Takahiro Ikeno ,  Masaaki Wakizaka

    发明人： Noriko MISUMI ,  Ayako Sakai ,  Takahiro Ikeno ,  Masaaki Wakizaka

    IPC分类号： G06F3/12

    CPC分类号： H04N1/00413 ,  H04N1/00411 ,  H04N1/00416 ,  H04N1/00474 ,  H04N2201/0094

    摘要： A multi function peripheral with a plurality of functions includes a function selecting unit accepting therethrough an input to select a function to be executed from the plurality of functions, a display unit displaying thereon an information screen showing information on the function selected through the function selecting unit, and a display control unit controlling the display unit to, each time a function is selected through the function selecting unit, display thereon a first information screen showing information on the selected function. When a second information screen showing information on a function in execution has been displayed on the display unit, the display control unit controls the display unit to display thereon the first information screen concurrently with the second information screen.

    摘要翻译： 具有多个功能的多功能外围设备包括：功能选择单元，从其接受输入以从多个功能中选择要执行的功能;显示单元，其上显示有关通过功能选择单元选择的功能的信息的信息屏幕 以及显示控制单元，其通过功能选择单元在每次选择功能时控制显示单元，在其上显示表示关于所选功能的信息的第一信息屏幕。 当在显示单元上显示表示执行功能的信息的第二信息屏幕时，显示控制单元控制显示单元在其上显示与第二信息画面同时的第一信息画面。

    Multi function peripheral and method therfor
    2.
    发明授权
    Multi function peripheral and method therfor 有权
    多功能外围设备和方法

    公开(公告)号：US08446600B2

    公开(公告)日：2013-05-21

    申请号：US12179041

    申请日：2008-07-24

    申请人： Noriko Misumi ,  Ayako Sakai ,  Takahiro Ikeno ,  Masaaki Wakizaka

    发明人： Noriko Misumi ,  Ayako Sakai ,  Takahiro Ikeno ,  Masaaki Wakizaka

    IPC分类号： G06F3/12

    CPC分类号： H04N1/00413 ,  H04N1/00411 ,  H04N1/00416 ,  H04N1/00474 ,  H04N2201/0094

    摘要： A multi function peripheral with a plurality of functions includes a function selecting unit accepting therethrough an input to select a function to be executed from the plurality of functions, a display unit displaying thereon an information screen showing information on the function selected through the function selecting unit, and a display control unit controlling the display unit to, each time a function is selected through the function selecting unit, display thereon a first information screen showing information on the selected function. When a second information screen showing information on a function in execution has been displayed on the display unit, the display control unit controls the display unit to display thereon the first information screen concurrently with the second information screen.

    摘要翻译： 具有多个功能的多功能外围设备包括：功能选择单元，从其接受输入以从多个功能中选择要执行的功能;显示单元，其上显示有关通过功能选择单元选择的功能的信息的信息屏幕 以及显示控制单元，其通过功能选择单元在每次选择功能时控制显示单元，在其上显示表示关于所选功能的信息的第一信息屏幕。 当在显示单元上显示表示执行功能的信息的第二信息屏幕时，显示控制单元控制显示单元在其上显示与第二信息画面同时的第一信息画面。

    METHOD FOR DETERMINING PRESENCE OR ABSENCE OF EPITHELIAL CANCER-ORIGIN CELL IN BIOLOGICAL SAMPLE, AND MOLECULAR MARKER AND KIT THEREFOR
    4.
    发明申请
    METHOD FOR DETERMINING PRESENCE OR ABSENCE OF EPITHELIAL CANCER-ORIGIN CELL IN BIOLOGICAL SAMPLE, AND MOLECULAR MARKER AND KIT THEREFOR 审中-公开
    用于确定生物样品中上位癌细胞存在或不存在的方法及其分子标记和试剂盒

    公开(公告)号：US20120190024A1

    公开(公告)日：2012-07-26

    申请号：US13381620

    申请日：2010-06-30

    申请人： Kaya Tai ,  Masahiro Kajita ,  Yoshihiko Tashima ,  Ayako Sakai

    发明人： Kaya Tai ,  Masahiro Kajita ,  Yoshihiko Tashima ,  Ayako Sakai

    IPC分类号： C12Q1/68 ,  C07H21/04

    CPC分类号： C12Q1/6886 ,  C12Q2600/154

    摘要： The present invention provides a method for determination of presence or absence of an epithelial cancer-derived cell in a biological sample obtained from a subject comprising the steps of: extracting DNA from the biological sample, analyzing methylation status of a CpG site located in at least one region represented by base sequences SEQ ID NOs: 1, 2, 3 and 4 in the DNA obtained from the step of extracting, and determining presence or absence of the epithelial cancer-derived cell in the biological sample based on an analysis result obtained from the step of analyzing.

    摘要翻译： 本发明提供一种用于确定从受试者获得的生物样品中存在或不存在上皮癌衍生细胞的方法，包括以下步骤：从生物样品中提取DNA，分析至少位于至少一个CpG位点的甲基化状态 由从提取步骤获得的DNA中的碱基序列SEQ ID NO：1,2,3和4表示的一个区域，并且基于从生物样品中获得的分析结果确定生物样品中上皮癌来源的细胞的存在或不存在 分析的步骤。

    Image reading devices
    5.
    发明授权
    Image reading devices 有权
    图像读取装置

    公开(公告)号：US08300279B2

    公开(公告)日：2012-10-30

    申请号：US12410450

    申请日：2009-03-24

    申请人： Takaaki Mukai ,  Yoshinori Osakabe ,  Ayako Sakai

    发明人： Takaaki Mukai ,  Yoshinori Osakabe ,  Ayako Sakai

    IPC分类号： H04N1/04 ,  H04N1/21 ,  G06F3/12 ,  H01L27/00 ,  H01L23/62 ,  H01R13/62 ,  H03K17/00 ,  F16M11/00 ,  G03G15/00 ,  B41J2/175 ,  H05K9/00

    CPC分类号： H04N1/1017 ,  H04N1/0083 ,  H04N1/1026 ,  H04N1/103 ,  H04N1/193 ,  H04N2201/0081 ,  H04N2201/0456

    摘要： The invention describes an image reading device having a housing, a transparent panel, an image sensor, a carriage, and an electric cable. The housing has a first, second, and third surface. The transparent panel defines a portion of the first surface. The image sensor extends in a first direction, and is mounted to the carriage and optically reads a document through the transparent panel while the carriage reciprocates in a second direction. The electric cable is electrically connected to the image sensor, and includes a band surface portion having a band surface and extending in a third direction intersecting the first and second direction. The electric cable also has a first end portion attached to the carriage; and a second end portion attached to the second surface. At least a portion of the electric cable is twisted such that the band surface and the third surface are not parallel.

    摘要翻译： 本发明描述了一种具有外壳，透明面板，图像传感器，滑架和电缆的图像读取装置。 壳体具有第一，第二和第三表面。 透明面板限定第一表面的一部分。 图像传感器沿第一方向延伸，并且当滑架沿第二方向往复运动时，安装到托架并通过透明面板光学读取文件。 电缆电连接到图像传感器，并且包括具有带表面并沿与第一和第二方向相交的第三方向延伸的带表面部分。 电缆还具有附接到托架的第一端部; 以及附接到第二表面的第二端部。 电缆的至少一部分被扭曲，使得带表面和第三表面不平行。

    Method of analyzing methylated DNA
    6.
    发明授权
    Method of analyzing methylated DNA 有权
    分析甲基化DNA的方法

    公开(公告)号：US08163490B2

    公开(公告)日：2012-04-24

    申请号：US12403167

    申请日：2009-03-12

    申请人： Ayako Sakai ,  Masahiro Kajita ,  Hideki Ishihara

    发明人： Ayako Sakai ,  Masahiro Kajita ,  Hideki Ishihara

    IPC分类号： C12Q1/68 ,  C12P19/34

    CPC分类号： C12Q1/6827 ,  C12Q2521/331 ,  C12Q2531/113

    摘要： The present invention provides a method of analyzing methylated DNA, comprising steps of: (A) treating a DNA-containing sample with a restriction enzyme to obtain a sample containing a DNA fragment; (B) concentrating methylated DNA contained in the sample obtained in step (A) to obtain a methylated DNA concentrate; (C) subjecting the methylated DNA concentrate obtained in step (B) and a primer set to nucleic acid amplification reaction, wherein the primer set performs the nucleic acid amplification reaction in step (C) by using a template DNA which does not have a CpG site; (D) detecting an amplification product obtained in step (C); (E) judging whether the methylated DNA concentrate obtained in step (B) is appropriate as a sample for detection of methylated DNA, on the basis of the detection result of the amplification product in step (D); and (F) analyzing the methylated DNA contained in the methylated DNA concentrate.

    摘要翻译： 本发明提供一种分析甲基化DNA的方法，包括以下步骤：（A）用限制酶处理含有DNA的样品，得到含有DNA片段的样品; （B）浓缩步骤（A）中获得的样品中所含的甲基化DNA以获得甲基化DNA浓缩物; （C）使步骤（B）中获得的甲基化DNA浓缩物和引物组进行核酸扩增反应，其中引物组通过使用不具有CpG的模板DNA进行步骤（C）中的核酸扩增反应 现场; （D）检测步骤（C）中获得的扩增产物; （E）基于步骤（D）中的扩增产物的检测结果判断步骤（B）中获得的甲基化DNA浓缩物是否适合作为检测甲基化DNA的样品; 和（F）分析甲基化DNA浓缩物中所含的甲基化DNA。

    Hybridoma producing anti-methylated DNA antibody and utilization of same
    7.
    发明授权
    Hybridoma producing anti-methylated DNA antibody and utilization of same 有权
    产生抗甲基化DNA抗体的杂交瘤及其利用

    公开(公告)号：US09169330B2

    公开(公告)日：2015-10-27

    申请号：US13430295

    申请日：2012-03-26

    申请人： Ayako Sakai ,  Masahiro Kajita

    发明人： Ayako Sakai ,  Masahiro Kajita

    IPC分类号： C07K16/18 ,  C07H1/06 ,  C12N5/16 ,  C07K16/44 ,  G01N33/53

    CPC分类号： C07K16/44 ,  C12N5/163 ,  G01N33/5308

    摘要： The present invention relates to a hybridoma producing an anti-methylated DNA antibody, obtained by cell fusion of an antibody-producing cell obtained from an animal immunized with an antigen containing 5′-(5-methyl-2′-deoxycytidine-3′-phospho)-2′-deoxyguanosine 3′-phosphate with a myeloma cell. The present invention also relates to a monoclonal antibody produced by the hybridoma and a method for immunoprecipitation of a methylated DNA using the antibody.

    摘要翻译： 本发明涉及产生抗甲基化DNA抗体的杂交瘤，该抗体通过细胞融合获得的抗体产生细胞获得，所述抗体产生细胞由含有5' - （5-甲基-2'-脱氧胞苷-3'- 磷酸）-2'-脱氧鸟苷3'-磷酸与骨髓瘤细胞。 本发明还涉及由该杂交瘤产生的单克隆抗体以及使用该抗体对甲基化DNA进行免疫沉淀的方法。

    Method for confirming conversion treatment and nucleic acid molecule used therefor
    10.
    发明申请
    Method for confirming conversion treatment and nucleic acid molecule used therefor 审中-公开
    用于确认转化处理的方法和用于其的核酸分子

    公开(公告)号：US20080096213A1

    公开(公告)日：2008-04-24

    申请号：US11902254

    申请日：2007-09-20

    申请人： Masahiro Kajita ,  Noriaki Yamamoto ,  Ayako Sakai ,  Hideki Ishihara

    发明人： Masahiro Kajita ,  Noriaki Yamamoto ,  Ayako Sakai ,  Hideki Ishihara

    IPC分类号： C12Q1/68 ,  C07H21/00

    CPC分类号： C12Q1/6827 ,  C12Q2565/1015 ,  C12Q2545/114 ,  C12Q2545/101

    摘要： There is provided a method for confirming conversion treatment of non-methylated cytosine, including a step of mixing a DNA taken from a living body, with a nucleic acid for accuracy control having a sequence A which is not contained in a genome of the living body and contains cytosine, a step of converting non-methylated cytosine in the mixture into a base other than cytosine, a step of detecting the sequence A and/or a sequence A′ which has a sequence obtained by converting cytosine in the sequence A into the base other than cytosine, and a step of determining whether the conversion step has been properly performed or not based on the result of the detection step.

    摘要翻译： 提供了一种确认非甲基化胞嘧啶的转化处理的方法，包括将从活体取得的DNA混合的步骤与用于精确控制的核酸的步骤，所述序列A不包含在生物体的基因组中 并含有胞嘧啶，将混合物中的非甲基化胞嘧啶转化为除胞嘧啶以外的碱基的步骤，检测序列A和/或A序列的步骤，其具有通过将序列A中的胞嘧啶转化为 碱基以外的碱基，以及基于检测步骤的结果确定转化步骤是否已经被适当地进行的步骤。