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公开(公告)号：US20190177182A1
公开(公告)日：2019-06-13
申请号：US16154624
申请日：2018-10-08
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee
CPC classification number: C02F1/288 , B01J20/262 , B01J20/28016 , B01J20/28019 , B01J20/3204 , B01J20/3206 , B01J20/3208 , B01J20/3272 , B01J20/3293 , B01J20/345 , B01J20/3475 , C02F1/285 , C02F1/286 , C02F2101/006 , C02F2101/20 , C02F2101/22 , C02F2101/30 , C02F2101/38 , C02F2303/16
Abstract: A bio-inspired method for detoxifying contaminated water is disclosed. In the method, polydopamine, a mussel-inspired adhesive catecholamine was used as an adsorbent to effectively remove from contaminated water three major classes of toxic agents: heavy metal ions (e.g., Cr, Hg, Pb, Cu, and Cd), toxic organic species (e.g., 4-aminopyridine), and radioisotopes (e.g., Lutetium-177). Furthermore, the polydopamine adsorbent was regenerated by treatment with acid or hydrogen peroxide.
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公开(公告)号：US09296843B2
公开(公告)日：2016-03-29
申请号：US14294640
申请日：2014-06-03
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee , Yuhan Lee , Zhongqiang Liu , Lesley Hamming
IPC: C08F26/02 , C08F126/02 , B05D7/00 , C08B37/08 , C08G69/48 , C08G83/00 , C08G85/00 , C08G73/02 , B05D3/00 , C08G63/66 , C08G65/48 , C08G73/04
CPC classification number: C08F126/02 , B05D7/52 , C08B37/0072 , C08F26/02 , C08G69/48 , C08G73/0206 , C08G83/00 , C08G85/004
Abstract: The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.
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公开(公告)号：US10093557B2
公开(公告)日：2018-10-09
申请号：US15090222
申请日：2016-04-04
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee
IPC: C02F1/28 , B01J20/26 , B01J20/32 , B01J20/34 , B01J20/28 , C02F101/22 , C02F101/00 , C02F101/20 , C02F101/30 , C02F101/38
Abstract: A bio-inspired method for detoxifying contaminated water is disclosed. In the method, polydopamine, a mussel-inspired adhesive catecholamine was used as an adsorbent to effectively remove from contaminated water three major classes of toxic agents: heavy metal ions (e.g., Cr, Hg, Pb, Cu, and Cd), toxic organic species (e.g., 4-aminopyridine), and radioisotopes (e.g., Lutetium-177). Furthermore, the polydopamine adsorbent was regenerated by treatment with acid or hydrogen peroxide.
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公开(公告)号：US20160318774A1
公开(公告)日：2016-11-03
申请号：US15090222
申请日：2016-04-04
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee
CPC classification number: C02F1/288 , B01J20/262 , B01J20/28016 , B01J20/28019 , B01J20/3204 , B01J20/3206 , B01J20/3208 , B01J20/3272 , B01J20/3293 , B01J20/345 , B01J20/3475 , C02F1/285 , C02F1/286 , C02F2101/006 , C02F2101/20 , C02F2101/22 , C02F2101/30 , C02F2101/38 , C02F2303/16
Abstract: A bio-inspired method for detoxifying contaminated water is disclosed. In the method, polydopamine, a mussel-inspired adhesive catecholamine was used as an adsorbent to effectively remove from contaminated water three major classes of toxic agents: heavy metal ions (e.g., Cr, Hg, Pb, Cu, and Cd), toxic organic species (e.g., 4-aminopyridine), and radioisotopes (e.g., Lutetium-177). Furthermore, the polydopamine adsorbent was regenerated by treatment with acid or hydrogen peroxide.
Abstract translation: 公开了一种用于解毒污染水的生物启发方法。 在这种方法中，使用了聚多巴胺，一种采用贻贝的粘合剂儿茶酚胺作为吸附剂，有效地从受污染的水中去除了三种主要的毒素：重金属离子（如Cr，Hg，Pb，Cu和Cd），有毒有机物 物种（例如4-氨基吡啶）和放射性同位素（例如，镥-177）。 此外，通过用酸或过氧化氢处理再生聚多巴胺吸附剂。
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5.发明申请Surface-Independent, Surface-Modifying, Multifunctional Coatings and Applications Thereof 有权表面独立，表面改性，多功能涂料及其应用公开(公告)号：US20160046815A1
公开(公告)日：2016-02-18
申请号：US14638303
申请日：2015-03-04
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee
CPC classification number: C09D5/1662 , A61L2420/00 , A61L2420/08 , B05D1/185 , B05D5/00 , B05D7/5483 , C02F1/281 , C02F1/285 , C02F1/288 , C02F2101/20 , C08J7/123 , C09D5/1681 , C09D179/04 , C23C18/1608 , C23C18/1803 , C23C18/1834 , C23C18/1844 , C23C18/2006 , C23C18/2066 , C23C18/31 , C23C18/40 , C23C18/42
Abstract: The present invention provides a surface-independent surface-modifying multifunctional biocoating and methods of application thereof. The method comprises contacting at least a portion of a substrate with an alkaline solution comprising a surface-modifying agent (SMA) such as dopamine so as to modify the substrate surface to include at least one reactive moiety. In another version of the invention, a secondary reactive moiety is applied to the SMA-treated substrate to yield a surface-modified substrate having a specific functionality.
Abstract translation: 本发明提供了一种与表面无关的表面改性多功能生物涂层及其应用方法。 该方法包括使至少一部分底物与包含表面改性剂（SMA）如多巴胺的碱性溶液接触，以便改变底物表面以包括至少一个反应性部分。 在本发明的另一个方案中，将第二反应性部分施加到经SMA处理的基底上以产生具有特定官能度的表面改性底物。
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Patent Agency Ranking
公开(公告)号：US20140329967A1
公开(公告)日：2014-11-06
申请号：US14294640
申请日：2014-06-03
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee , Yuhan Lee , Zhongqiang Liu , Lesley Hamming
IPC: C08F126/02 , C08G73/02
CPC classification number: C08F126/02 , B05D7/52 , C08B37/0072 , C08F26/02 , C08G69/48 , C08G73/0206 , C08G83/00 , C08G85/004
Abstract: The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.
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公开(公告)号：US10829393B2
公开(公告)日：2020-11-10
申请号：US16154624
申请日：2018-10-08
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee
IPC: C02F1/28 , B01J20/26 , B01J20/32 , B01J20/34 , B01J20/28 , C02F101/22 , C02F101/00 , C02F101/20 , C02F101/30 , C02F101/38
Abstract: A bio-inspired method for detoxifying contaminated water is disclosed. In the method, polydopamine, a mussel-inspired adhesive catecholamine was used as an adsorbent to effectively remove from contaminated water three major classes of toxic agents: heavy metal ions (e.g., Cr, Hg, Pb, Cu, and Cd), toxic organic species (e.g., 4-aminopyridine), and radioisotopes (e.g., Lutetium-177). Furthermore, the polydopamine adsorbent was regenerated by treatment with acid or hydrogen peroxide.
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8.发明申请公开(公告)号：US20170166756A1
公开(公告)日：2017-06-15
申请号：US15178255
申请日：2016-06-09
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee
IPC: C09D5/16 , C09D179/04
CPC classification number: C09D5/1662 , A61L2420/00 , A61L2420/08 , B05D1/185 , B05D5/00 , B05D7/5483 , C02F1/281 , C02F1/285 , C02F1/288 , C02F2101/20 , C08J7/123 , C09D5/1681 , C09D179/04 , C23C18/1608 , C23C18/1803 , C23C18/1834 , C23C18/1844 , C23C18/2006 , C23C18/2066 , C23C18/31 , C23C18/40 , C23C18/42
Abstract: The present invention provides a surface-independent surface-modifying multifunctional biocoating and methods of application thereof. The method comprises contacting at least a portion of a substrate with an alkaline solution comprising a surface-modifying agent (SMA) such as dopamine so as to modify the substrate surface to include at least one reactive moiety. In another version of the invention, a secondary reactive moiety is applied to the SMA-treated substrate to yield a surface-modified substrate having a specific functionality.
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9.发明授权Method of coating 3,4-dihydroxyphenylalanine-based (DOPA) coatings onto substrates for adhering metal from fluids onto the substrate 有权将3,4-二羟基苯丙氨酸（DOPA）涂层涂覆在基材上以将金属从流体粘附到基材上的方法公开(公告)号：US09371455B2
公开(公告)日：2016-06-21
申请号：US14638303
申请日：2015-03-04
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee
IPC: B05D5/00 , C02F1/28 , C09D5/16 , B05D7/00 , C02F101/20
CPC classification number: C09D5/1662 , A61L2420/00 , A61L2420/08 , B05D1/185 , B05D5/00 , B05D7/5483 , C02F1/281 , C02F1/285 , C02F1/288 , C02F2101/20 , C08J7/123 , C09D5/1681 , C09D179/04 , C23C18/1608 , C23C18/1803 , C23C18/1834 , C23C18/1844 , C23C18/2006 , C23C18/2066 , C23C18/31 , C23C18/40 , C23C18/42
Abstract: The present invention provides a surface-independent surface-modifying multifunctional biocoating and methods of application thereof. The method comprises contacting at least a portion of a substrate with an alkaline solution comprising a surface-modifying agent (SMA) such as dopamine so as to modify the substrate surface to include at least one reactive moiety. In another version of the invention, a secondary reactive moiety is applied to the SMA-treated substrate to yield a surface-modified substrate having a specific functionality.
Abstract translation: 本发明提供了一种与表面无关的表面改性多功能生物涂层及其应用方法。 该方法包括使至少一部分底物与包含表面改性剂（SMA）如多巴胺的碱性溶液接触，以便改变底物表面以包括至少一个反应性部分。 在本发明的另一个方案中，将第二反应性部分施加到经SMA处理的基底上以产生具有特定官能度的表面改性底物。
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10.发明申请SUBSTRATE-INDEPENDENT LAYER-BY-LAYER ASSEMBLY USING CATECHOL-FUNCTIONALIZED POLYMERS 有权使用CATECHOL官能化聚合物的基板独立层叠组件公开(公告)号：US20130017332A1
公开(公告)日：2013-01-17
申请号：US13622136
申请日：2012-09-18
Applicant: Northwestern University
Inventor： Phillip B. Messersmith , Haeshin Lee , Yuhan Lee , Zhongqiang Liu , Lesley Hamming
CPC classification number: C08F126/02 , B05D7/52 , C08B37/0072 , C08F26/02 , C08G69/48 , C08G73/0206 , C08G83/00 , C08G85/004
Abstract: The present invention provides a simple, non-destructive and versatile method that enables layer-by-layer (LbL) assembly to be performed on virtually any substrate. A novel catechol-functionalized polymer which adsorbs to virtually all surfaces and can serve as a platform for LbL assembly in a surface-independent fashion is also provided.
Abstract translation: 本发明提供了一种简单的，非破坏性和通用的方法，其能够在几乎任何基底上执行逐层（LbL）组件。 还提供了一种新颖的儿茶酚官能化聚合物，其吸附到几乎所有表面并且可以作为以表面无关的方式用于LbL组装的平台。
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