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公开(公告)号：US11167069B2
公开(公告)日：2021-11-09
申请号：US16575482
申请日：2019-09-19
发明人： Goetz Friederichs , William K. Weigel , Dennis M. Treu , Jeffrey H. Burbank , James M. Brugger , Keith David J. Wheeler , Scott W. Newell
IPC分类号： A61M1/16 , A61K31/191 , B01F1/00 , C02F9/00 , F15B1/04 , C02F1/20 , C02F1/28 , C02F1/42 , C02F1/44 , C02F103/02 , C02F103/04
摘要： A medicament preparation system, according to an embodiment, includes a water purification module and a medicament proportioning module. The system is configured to allow convenient and safe use in a home environment or a critical care environment as well as others affording safety, reliability, and a compact form factor.
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公开(公告)号：US10130746B2
公开(公告)日：2018-11-20
申请号：US15195801
申请日：2016-06-28
IPC分类号： A61M1/16 , B01D61/22 , C02F1/44 , B01D61/14 , B01D61/32 , B01D61/06 , B01D61/24 , B01D61/28 , C02F1/42 , C02F1/28 , A61M3/00 , C02F1/32 , C02F103/02
摘要： Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed through a first filtration step which is effective for creating purified water and a pair of ultrafilters placed at the outlet. The ultrafilters are separated by an intervening flow path to prevent grow-through from the outlet end upstream. In embodiments, a recirculation path with an air removing filter helps to eliminate air from the ultimate product water.
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公开(公告)号：US09388059B2
公开(公告)日：2016-07-12
申请号：US13968430
申请日：2013-08-16
CPC分类号： A61M1/1656 , A61M1/14 , A61M1/166 , A61M1/167 , A61M1/1672 , A61M1/1674 , A61M1/28 , A61M1/288 , A61M1/3462 , A61M2205/12 , C02F1/44
摘要： Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed through a first filtration step which is effective for creating purified water and a pair of ultrafilters placed at the outlet. The ultrafilters are separated by an intervening flow path to prevent grow-through from the outlet end upstream. In embodiments, a recirculation path with an air removing filter helps to eliminate air from the ultimate product water.
摘要翻译： 描述了用于制备包括血液处理在内的各种用途的水的系统，方法和装置。 在实施例中，流体通过第一过滤步骤，其有效地用于产生净化水和放置在出口处的一对超滤器。 超滤器由中间流动路径隔开，以防止从上游的出口端伸出。 在实施例中，具有空气去除过滤器的再循环路径有助于消除来自最终产品水的空气。
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公开(公告)号：US10960121B2
公开(公告)日：2021-03-30
申请号：US15924425
申请日：2018-03-19
IPC分类号： A61M1/16 , C02F1/28 , C02F1/42 , C02F1/00 , C02F1/44 , C02F103/02 , C02F1/32 , C02F101/12
摘要： A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.
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公开(公告)号：US10189728B2
公开(公告)日：2019-01-29
申请号：US15214438
申请日：2016-07-19
摘要： A fluid purification system has cells whose purifying capability can be regenerated. Some of the cells are arranged in series to reach a high level of purification. An automatic valve network is controlled to cycle the cells in a way that levels the loads on each, thereby maximizing the service interval for replacing expired cells, enabling all of the cells to be replaced at the same time after having each contributing approximately equally to the purification load, and operated such that at any one time, at least one cell is regenerated so as to enable continuous up-time.
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公开(公告)号：US20130146541A1
公开(公告)日：2013-06-13
申请号：US13713767
申请日：2012-12-13
IPC分类号： C02F1/44
CPC分类号： C02F1/4695 , B01D61/42 , B01D61/52 , B01D61/54 , B01D65/02 , B01D2317/02 , B01D2321/04 , B01D2321/12 , C02F1/006 , C02F1/008 , C02F1/32 , C02F1/441 , C02F1/444 , C02F2201/46115 , C02F2201/4613 , C02F2201/46145 , C02F2209/003 , C02F2209/005 , C02F2209/40 , C02F2301/08 , C02F2303/16 , Y10T137/8593
摘要： A fluid purification system has cells whose purifying capability can be regenerated. Some of the cells are arranged in series to reach a high level of purification. An automatic valve network is controlled to cycle the cells in a way that levels the loads on each, thereby maximizing the service interval for replacing expired cells, enabling all of the cells to be replaced at the same time after having each contributing approximately equally to the purification load, and operated such that at any one time, at least one cell is regenerated so as to enable continuous up-time.
摘要翻译： 流体净化系统具有能够再生净化能力的细胞。 一些细胞串联排列以达到高水平的纯化。 控制自动阀网络以使每个电池的负载平衡的方式循环电池，从而最大化用于替换过期电池的服务间隔，使得所有电池在每次贡献大致相等于之后同时被更换 净化负载，并且操作使得在任何一个时间，再生至少一个电池，以便能够连续正常运行。
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公开(公告)号：US11607482B2
公开(公告)日：2023-03-21
申请号：US17122772
申请日：2020-12-15
发明人： David Desouza , Daniel Joseph Rubery, Jr. , Dennis M. Treu , Mark T. Wyeth , Jerome James , Garrett D. Casey , James M. Brugger , William J. Schnell , Jeffrey H. Burbank , Goetz Friederichs
摘要： The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.
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公开(公告)号：US11446417B2
公开(公告)日：2022-09-20
申请号：US16164047
申请日：2018-10-18
IPC分类号： A61M1/16 , B01D61/06 , B01D61/14 , B01D61/22 , B01D61/24 , B01D61/28 , C02F1/42 , C02F1/44 , B01D61/32 , C02F1/28 , A61M3/00 , C02F1/32 , C02F103/02
摘要： A treatment system for performing a treatment on a patient may include a treatment fluid preparation device having a pump connected by a fluid channel to a reservoir of a source fluid, the pump conveying the source fluid from the reservoir, through a filter, and combining the source fluid with a concentrate by pumping the source fluid with the concentrate to form a treatment fluid in a batch container. The treatment fluid preparation device may have a controller that controls a heater, the pump, and a memory. The controller starts the heater to warm the treatment fluid in the batch container at a time that is responsive to the treatment time stored in the memory. The controller also detects a pressure property of the filter to determine its integrity and outputs an indication of a failed batch if the pressure property indicates the integrity of the filter is insufficient.
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公开(公告)号：US10478544B2
公开(公告)日：2019-11-19
申请号：US15514230
申请日：2015-09-25
发明人： Goetz Friederichs , William Weigel , Dennis M. Treu , Jeffrey H. Burbank , James M. Brugger , Keith J. Wheeler , Scott W. Newell
IPC分类号： A61M1/16 , A61K31/191 , B01F1/00 , C02F9/00 , F15B1/04 , C02F1/20 , C02F1/28 , C02F1/42 , C02F1/44 , C02F103/02 , C02F103/04
摘要： A medicament preparation system, according to an embodiment, includes a water purification module and a medicament proportioning module. The system is configured to allow convenient and safe use in a home environment or a critical care environment as well as others affording safety, reliability, and a compact form factor.
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公开(公告)号：US10189727B2
公开(公告)日：2019-01-29
申请号：US15187689
申请日：2016-06-20
摘要： A fluid purification system has cells whose purifying capability can be regenerated. Some of the cells are arranged in series to reach a high level of purification. An automatic valve network is controlled to cycle the cells in a way that levels the loads on each, thereby maximizing the service interval for replacing expired cells, enabling all of the cells to be replaced at the same time after having each contributing approximately equally to the purification load, and operated such that at any one time, at least one cell is regenerated so as to enable continuous up-time.
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