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公开(公告)号:US12048791B2
公开(公告)日:2024-07-30
申请号:US16621824
申请日:2018-06-24
发明人: Mark T. Wyeth , Gregory Yantz , James Ian Johnson , James M. Brugger , Dennis M. Treu , Dritan Kurshumi , Jeffrey H. Burbank , William J. Schnell , Robert Paul McCarty
CPC分类号: A61M1/1672 , A61M1/154 , A61M1/155 , A61M1/156 , A61M1/1565 , A61M1/159 , A61M1/1668 , A61M1/287 , A61M39/22 , A61M2205/3331
摘要: Peritoneal dialysis admixing and/or treatment devices, methods, and systems are disclosed. The systems, methods, and devices provide high-level guarantees of sterility and employs relatively inexpensive disposable components to provide pumping. Disclosed systems, methods, and devices and features thereof are adapted for point of use generation of medicament. In particular admixing systems that employ independently-replaceable long term concentrate are disclosed. Features are directed to assurance of sterility and accurate admixing of water and concentrate to generate ready-to-use medicaments and other benefits.
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公开(公告)号:US11865243B2
公开(公告)日:2024-01-09
申请号:US16328443
申请日:2017-08-30
发明人: Mark T. Wyeth , Robert Paul McCarty , Gregory Yantz , James Ian Johnson , Joseph E. Turk, Jr. , James M. Brugger , Jeffrey H. Burbank
CPC分类号: A61M1/3639 , A61M1/1611 , A61M1/1621 , A61M1/3623 , A61M2205/3344 , A61M2205/52 , A61M2230/207
摘要: A blood treatment system with pressure sensors may be configured to control blood flow to and from the patient and use readings of the pressure sensors to determine a change in a pressure drop across a flow restriction in the blood circuit to estimate a condition of the machine or the patient, or outputting data responsive to the estimation. Further embodiments employ measurement of pressure drop to detect abnormal viscosity or viscosity variations in order to detect possible infection.
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公开(公告)号:US11865240B2
公开(公告)日:2024-01-09
申请号:US17189879
申请日:2021-03-02
IPC分类号: A61M1/16 , C02F1/28 , C02F1/42 , C02F1/00 , C02F1/44 , C02F103/02 , C02F1/32 , C02F101/12
CPC分类号: A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/1672 , C02F1/283 , C02F1/42 , C02F1/001 , C02F1/32 , C02F1/441 , C02F2001/427 , C02F2101/12 , C02F2103/026 , C02F2209/003 , C02F2209/02 , C02F2209/05 , C02F2209/29 , C02F2209/445
摘要: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.
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公开(公告)号:US11717601B2
公开(公告)日:2023-08-08
申请号:US17412846
申请日:2021-08-26
CPC分类号: A61M1/282 , A61M1/166 , A61M1/167 , A61M1/1656 , A61M1/1664 , A61M1/1668 , A61M1/1672 , A61M1/1674 , A61M1/28 , A61M1/281 , A61M1/285 , A61M1/287 , A61M1/288 , A61M2025/0002 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/14 , A61M2205/18 , A61M2205/33 , A61M2205/3331 , A61M2205/3334 , A61M2205/3351 , A61M2205/3355 , A61M2205/52 , A61M2230/005
摘要: A treatment device system includes a treatment machine for performing a therapy on a patient, the treatment machine including at least one fluid conveyor and a controller, the controller having a first memory, to cause the at least one fluid conveyor to produce a therapeutic fluid by mixing purified water and at least one concentrate. The system also includes and a water purifier in fluid communication with and providing the purified water to the treatment machine. A wired or wireless control line provides two way communication between the controller of the treatment machine and the internal central controller of the water purifier, wherein the controller of the treatment machine transmits data via the control line to the internal central controller of the water purifier for control of the water purifier, the data provided based on at least one of the operator inputs received via the user interface.
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公开(公告)号:US11529448B2
公开(公告)日:2022-12-20
申请号:US16420249
申请日:2019-05-23
发明人: James M. Brugger , Dennis M. Treu , Jeffrey H. Burbank , Scott W. Newell , William J. Schnell , Kenneth E. Buckler
摘要: A pressure measurement pod for use in blood circuits includes a pressure sensing pod defining a chamber and having a rigid wall portion and an integral flexible wall portion forming a flexible, moveable, fluid-impermeable diaphragm with a first major side thereof facing an interior of the chamber and a second major side opposite the first major side. The second major side faces outwardly away from the chamber, and the pod has ports on sides of the chamber. The internal surfaces of the chamber and ports are shaped such that any contour following the internal surfaces to the outside of one of the ports traces only surfaces characterized by positive or neutral draft angles such that invasive mold portions may be withdrawn through the ports thereby permitting the pressure measurement pod to be molded in a single shot molding process.
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公开(公告)号:US11135348B2
公开(公告)日:2021-10-05
申请号:US15820672
申请日:2017-11-22
申请人: NXSTAGE MEDICAL INC.
摘要: An automated peritoneal dialysis system provides both cycler-assisted peritoneal dialysis treatment and also continuous ambulatory peritoneal dialysis (CAPD). The system includes a fluid preparation and treatment device with a concentrate dilution components connected to a source of purified water and medicament concentrate. The treatment device has at least one mixing container connected via a pump and valves to the sources, the valves and the pump mixing and diluting the concentrate to form a medicament. An auxiliary port is provided for attaching a CAPD container and for receiving medicament. A controller is programmed to control the fluid preparation and treatment device to implement one or more cycler-assisted peritoneal dialysis treatment cycles using medicament from the mixing container and also to control the preparation of additional dialysate at the end of the cycler-assisted peritoneal dialysis treatment cycles to dispense additional dialysate through the auxiliary port for use in CAPD.
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公开(公告)号:US10960121B2
公开(公告)日:2021-03-30
申请号:US15924425
申请日:2018-03-19
IPC分类号: A61M1/16 , C02F1/28 , C02F1/42 , C02F1/00 , C02F1/44 , C02F103/02 , C02F1/32 , C02F101/12
摘要: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.
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公开(公告)号:US10525182B2
公开(公告)日:2020-01-07
申请号:US15517928
申请日:2015-10-09
发明人: Jeffrey H. Burbank , Dennis M. Treu , Daniel J. Rubery, Jr. , Scott W. Newell , James M. Brugger , William J. Schnell , William K. Weigel , Steve A. White , Mark T. Wyeth , Jerome James , David Desouza , Joseph E. Turk, Jr. , Garrett Casey
摘要: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.
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公开(公告)号:US11896750B2
公开(公告)日:2024-02-13
申请号:US17212866
申请日:2021-03-25
发明人: Jeffrey H. Burbank , Dennis M. Treu , Goetz Friederichs , Brian C. Green , Christopher S. Mcdowell , James M. Brugger
CPC分类号: A61M1/1656 , A61M1/14 , A61M1/166 , A61M1/167 , A61M1/1668 , A61M1/1672 , A61M1/1674 , A61M1/288 , A61M1/3462 , C02F1/44 , A61M1/28 , A61M2205/12
摘要: A fluid treatment plant has a filter module including at least a first filter and a second filter connected in series and connectable to a supply of fluid. A pump is fluidly connected to the filter module and a controller with a fluid quality sensor is connected to detect a quality of the fluid between the first filter and the second filter. A filter module detector is connected to the controller configured to uniquely detect a filter module connected to the pump, and the controller is controls the pump responsively to a signal from the fluid quality sensor and the module detector. The controller is configured to continue pumping based on output of the quality sensor and/or based on output from the filter module detector.
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公开(公告)号:US20230338635A1
公开(公告)日:2023-10-26
申请号:US18218272
申请日:2023-07-05
CPC分类号: A61M1/3656 , A61M1/367 , G01M3/04 , Y10T137/5762 , A61M2205/15
摘要: Features for protecting against leaks in a fluid circuit are disclosed. In an embodiment, a first indicator of a leak is used to trigger confirmation by blood flow reversal and air detection in the blood circuit. A method for performing a blood treatment includes, at blood treatment machine, pumping blood to a patient through a first blood line. Further, at a controller of the blood treatment machine, a first signal is received, indicating a probability of a leak in the first blood line. Responsively to the first signal, the controller commands a leak verification operation and receives a second signal indicating whether a leak in the first blood line is verified. Further, a leak indicating signal is generated if the second signal indicates a leak is verified.
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