公开(公告)号：US20100254951A1

公开(公告)日：2010-10-07

申请号：US11884535

申请日：2006-02-22

申请人： Osamu Shido ,  Michio Hashimoto ,  Eisuke Kawakita ,  Tsuyoshi Harada

发明人： Osamu Shido ,  Michio Hashimoto ,  Eisuke Kawakita ,  Tsuyoshi Harada

IPC分类号： A61K35/30 ,  C07C57/03 ,  C07C57/12 ,  A61P25/00 ,  C12N5/0797

CPC分类号： A61K31/202 ,  A61K35/30 ,  C12N5/0619 ,  C12N2500/36 ,  C12N2500/90 ,  C12N2501/33 ,  C12N2533/32 ,  A61K2300/00

摘要： A neuronal differentiation promoting agent for neural stem cells comprising, as an active ingredient, at least one member selected from the group consisting of ω-3 unsaturated fatty acids and ω-6 unsaturated fatty acids having 18 to 22 carbon atoms, and derivatives thereof. The agent can be used for induction of differentiation of neural stem cells and is useful for treating and/or preventing a variety of neurological diseases, and in the fields of nerve transplantation and/or regenerative medicine for nerves.

摘要翻译： 作为神经干细胞的神经元分化促进剂，含有选自ω-3不饱和脂肪酸和碳原子数为18〜22的ω-6不饱和脂肪酸的至少1种成分作为有效成分及其衍生物。 该药剂可用于诱导神经干细胞的分化，并且可用于治疗和/或预防各种神经疾病，以及神经移植和/或神经再生医学领域。

公开(公告)号：US06184508B2

公开(公告)日：2001-02-06

申请号：US09352163

申请日：1999-07-12

申请人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

发明人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

IPC分类号： H05B640

CPC分类号： B21B15/0085 ,  B21B1/26 ,  B23K13/015 ,  B23K13/02 ,  B23K2101/18

摘要： An apparatus for joining metal pieces using induction heating. Preceding and succeeding metal pieces are followed by a carriage which carries an inductor. The inductor has the ability to move in the longitudinal direction of the metal pieces relative to the carriage to allow the inductor to move more or less upon the preceding or succeeding metal pieces to increase or decrease the induction heating effect, thereby taking into account any thickness variation of the metal pieces and yet still heating them evenly with regard to each other, prior to their being pressed against each other for joining before hot finishing rolling.

摘要翻译： 一种使用感应加热连接金属片的装置。 前面和后面的金属件之后是一个带有电感的托架。 电感器具有相对于托架在金属片的纵向上移动的能力，以允许电感器或多或少地前进或后续的金属片移动以增加或减少感应加热效应，从而考虑到任何厚度 金属片的变化，并且仍然在彼此相互压合之前彼此均匀加热，然后在热精轧之前彼此压合。

公开(公告)号：US06252211B1

公开(公告)日：2001-06-26

申请号：US09351463

申请日：1999-07-12

申请人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

发明人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

IPC分类号： H05B610

CPC分类号： B21B15/0085 ,  B21B1/26 ,  B23K13/015 ,  B23K13/02 ,  B23K2101/18

摘要： A method and apparatus for joining metal pieces wherein the rear end of a preceding metal piece and a front end of a metal piece are heated and then pressed together prior to hot finished rolling. The temperature the ends of the metal pieces are heated to is a temperature range between the solidus and liquidus line temperatures of the metal(s) to be joined.

摘要翻译： 一种接合金属片的方法和装置，其中先前金属片的后端和金属片的前端被加热，然后在热轧完成之前被压在一起。 金属片的端部的温度被加热到要接合的金属的固相线和液相线的温度之间的温度范围。

公开(公告)号：US06248984B1

公开(公告)日：2001-06-19

申请号：US09351372

申请日：1999-07-12

申请人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

发明人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

IPC分类号： H05B606

CPC分类号： B21B15/0085 ,  B21B1/26 ,  B23K13/015 ,  B23K13/02 ,  B23K2101/18

摘要： According to the invention, the rear end of a preceding metal piece and a front end of a succeeding metal piece are heated, pressed and joined prior to the finishing hot rolling. An alternating magnetic field running through the metal pieces in the thickness direction thereof is generated in an end region on opposed faces of the respective metal pieces to perform heating. Another alternating magnetic field whose direction is reverse with respect to that of the former alternating magnetic field is partially generated in the end region on the opposed faces of the metal pieces and in either a region where the metal pieces exist or a region outside width ends of the metal pieces. This assures a uniform heating of the end region on the opposed faces of the metal pieces over their full width to reliably join the both metal pieces to each other.

摘要翻译： 根据本发明，在精加工热轧之前，先前金属片的后端和后面的金属片的前端被加热，压制和接合。 在各个金属片的相对面上的端部区域中产生沿其厚度方向穿过金属片的交变磁场，以进行加热。 在金属片的相对面上的端部区域和金属片存在的区域或外侧宽度端部的区域中部分地产生相对于前者的交变磁场的方向相反的另一个交变磁场 金属件。 这确保了金属片的相对面上的端部区域在其全宽度上的均匀加热，以将两个金属片彼此可靠地接合。

公开(公告)号：US06354896B1

公开(公告)日：2002-03-12

申请号：US09506258

申请日：2000-02-17

申请人： Kazunori Morita ,  Michio Hashimoto

发明人： Kazunori Morita ,  Michio Hashimoto

IPC分类号： H01S400

CPC分类号： B01D46/0005 ,  B01D46/50 ,  B03C1/029 ,  B03C1/12 ,  Y10T29/49002

摘要： Before a hopper is mounted in a lower portion of a casing 12, a large number of discharge frames 14 are mounted through an open portion 39 of the hopper by a gate-shaped crane 41 arranged on the upper surface of the casing 12, followed by mounting a large number of movable electrodes 15 so as to be rotated around every other dischargeframe and finally mounting the hopper 13. The particular method permits carrying out efficiently the mounting operation of the discharge framesand the movable electrodes in assembling a movable electrode typed electric dust collecting apparatus.

摘要翻译： 在料斗安装在壳体12的下部之前，通过设置在壳体12的上表面上的门形起重机41，通过料斗的开口部分39安装大量的排出框架14，之后是 安装大量的可移动电极15，以便围绕每个其他放电架旋转，最后安装料斗13.特别的方法允许在组装可移动电极型集尘器中的放电框架和可移动电极的有效运行 仪器。

公开(公告)号：US06262402B1

公开(公告)日：2001-07-17

申请号：US09352164

申请日：1999-07-12

申请人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

发明人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

IPC分类号： H05B610

CPC分类号： B21B15/0085 ,  B21B1/26 ,  B23K13/015 ,  B23K13/02 ,  B23K2101/18

摘要： According to the invention, the rear end of a preceding metal piece and a front end of a succeeding metal piece are heated, pressed and joined prior to the finishing hot rolling. An alternating magnetic field running through the metal pieces in the thickness direction thereof is generated in an end region on opposed faces of the respective metal pieces to perform heating. Another alternating magnetic field whose direction is reverse with respect to that of the former alternating magnetic field is partially generated in the end region on the opposed faces of the metal pieces and in either a region where the metal pieces exist or a region outside width ends of the metal pieces. This assures a uniform heating of the end region on the opposed faces of the metal pieces over their full width to reliably join the both metal pieces to each other.

摘要翻译： 根据本发明，在精加工热轧之前，先前金属片的后端和后面的金属片的前端被加热，压制和接合。 在各个金属片的相对面上的端部区域中产生沿其厚度方向穿过金属片的交变磁场，以进行加热。 在金属片的相对面上的端部区域和金属片存在的区域或外侧宽度端部的区域中部分地产生相对于前者的交变磁场的方向相反的另一个交变磁场 金属件。 这确保了金属片的相对面上的端部区域在其全宽度上的均匀加热，以将两个金属片彼此可靠地接合。

公开(公告)号：US06218649B1

公开(公告)日：2001-04-17

申请号：US09352157

申请日：1999-07-12

申请人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

发明人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

IPC分类号： H05B610

CPC分类号： B21B15/0085 ,  B21B1/26 ,  B23K13/015 ,  B23K13/02 ,  B23K2101/18

摘要： Method and apparatus for joining metal pieces using induction heating. Metal pieces to be joined are placed end-to-end with a gap between them and induction heated in the thickness portion. To maximize speed and even heating edge-to-edge of the ends, members of a magnetic substance are provided in a gap between the inductor and the piece to be heated, thereby enhancing local heating effect by increasing magnetic flux density. Once heated, the ends are pressed together end-to-end for joining.

摘要翻译： 使用感应加热连接金属件的方法和装置。 要连接的金属片端对端放置，并在厚度部分进行感应加热。 为了最大化速度，甚至加热端部的边缘到边缘，磁性物质的构件设置在电感器和待加热件之间的间隙中，从而通过增加磁通密度来增强局部加热效果。 一旦被加热，端部端对端地被压在一起用于接合。

公开(公告)号：US5951903A

公开(公告)日：1999-09-14

申请号：US513789

申请日：1995-12-29

申请人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

发明人： Shigeru Isoyama ,  Takeshi Hirabayashi ,  Hideyuki Nikaido ,  Toshiaki Amagasa ,  Nozomu Tamura ,  Takahiro Yamasaki ,  Masashi Osada ,  Hirosuke Yamada ,  Toshisada Takechi ,  Norio Takashima ,  Junzo Nitta ,  Shuji Amanuma ,  Kanji Hayashi ,  Akio Kuroda ,  Yoshiki Mito ,  Kunio Miyamoto ,  Kazuo Morimoto ,  Ikuo Wakamoto ,  Kazuya Tsurusaki ,  Hideo Sakamoto ,  Michio Hashimoto ,  Hiroyuki Nakano ,  Toshinobu Eguchi ,  Fumihiro Maeda

IPC分类号： B21B1/26 ,  B21B15/00 ,  B23K13/01 ,  B23K13/02 ,  H05B6/10 ,  B21B45/00

CPC分类号： B21B15/0085 ,  B23K13/015 ,  B23K13/02 ,  B21B1/26 ,  B23K2201/18

摘要： According to the invention, the rear end of a preceding metal piece and a front end of a succeeding metal piece are heated, pressed and joined prior to the finishing hot rolling. An alternating magnetic field running through the metal pieces in the thickness direction thereof is generated in an end region on opposed faces of the respective metal pieces to perform heating. Another alternating magnetic field whose direction is reverse with respect to that of the former alternating magnetic field is partially generated in the end region on the opposed faces of the metal pieces and in either a region where the metal pieces exist or a region outside width ends of the metal pieces. This assures a uniform heating of the end region on the opposed faces of the metal pieces over their full width to reliably join the both metal pieces to each other.

摘要翻译： PCT No.PCT / JP94 / 02113 Sec。 371 1995年12月29日第 102（e）1995年12月29日PCT PCT 1994年12月15日PCT公布。 公开号WO95 / 16525 日期：1995年6月22日根据本发明，在精加工热轧之前，先前金属片的后端和后面的金属片的前端被加热，压制和接合。 在各个金属片的相对面上的端部区域中产生沿其厚度方向穿过金属片的交变磁场，以进行加热。 在金属片的相对面上的端部区域和金属片存在的区域或外侧宽度端部的区域中部分地产生相对于前者的交变磁场的方向相反的另一个交变磁场 金属件。 这确保了金属片的相对面上的端部区域在其全宽度上的均匀加热，以将两个金属片彼此可靠地接合。

公开(公告)号：US5166184A

公开(公告)日：1992-11-24

申请号：US873685

申请日：1992-04-24

申请人： Michio Hashimoto ,  Taira Harada ,  Yoshihisa Kiso ,  Isao Kaneko ,  Gorou Suzuki

发明人： Michio Hashimoto ,  Taira Harada ,  Yoshihisa Kiso ,  Isao Kaneko ,  Gorou Suzuki

IPC分类号： C08G59/06 ,  C08G59/24 ,  C08G59/62 ,  C08J9/02 ,  C08J9/08

CPC分类号： C08J9/08 ,  C08G59/063 ,  C08G59/245 ,  C08G59/621 ,  C08J9/02 ,  C08J2363/00

摘要： A normally liquid epoxy resin obtainable by reaction of a bisphenol based oligocarbonate having terminal phenolic hydroxyl groups with an epihalohydrin, followed by dehydrohalogenation. The epoxy resin is capable of forming a tough cured product having improved flexural strength and flexural modulus. A process for the production of an epoxy resin foam in which a polyepoxy compound is crosslinked and simultaneously foamed by the aid of carbonate oligomers having terminal phenolic hydroxyl groups. The product is highly flexible against compression, bending and warp.

摘要翻译： 通过具有末端酚羟基的双酚型低聚碳酸酯与表卤代醇反应得到的常规环氧树脂，然后脱卤化氢。 环氧树脂能够形成具有改善的弯曲强度和弯曲模量的韧性固化产物。 一种制备环氧树脂泡沫的方法，其中聚环氧化合物通过具有末端酚羟基的碳酸酯低聚物交联并同时发泡。 该产品对抗压缩，弯曲和翘曲具有高度的灵活性。

公开(公告)号：US5037899A

公开(公告)日：1991-08-06

申请号：US605150

申请日：1990-10-31

申请人： Hideo Nakamura ,  Masaru Wakizaka ,  Michio Hashimoto ,  Yohzoh Yamamoto

发明人： Hideo Nakamura ,  Masaru Wakizaka ,  Michio Hashimoto ,  Yohzoh Yamamoto

IPC分类号： C08G59/16 ,  C08G59/02 ,  C08G59/14 ,  C08G59/56 ,  C08G59/62 ,  C09D5/03 ,  C09D163/00

CPC分类号： C08G59/56 ,  C08G59/625

摘要： A modified epoxy resin provided with improved flexibility and curing properties is prepared by subjecting a bisphenol type epoxy resin (a) to steps (i) and (ii):(i) the step wherein the epoxy group is reacted with a primary amine (b), and(ii) the step wherein secondary hydroxyl group is at least partly esterified by a reaction with a lactone.