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公开(公告)号：US20130098780A1
公开(公告)日：2013-04-25
申请号：US13576561
申请日：2011-01-28
IPC分类号： G01N27/416
CPC分类号： G01N27/4163 , G01N27/4145 , G01N33/4836
摘要： A sensor system comprising a substrate and integrated onto the substrate an array (7) of sensor elements (1), each sensor element comprising one or more inductors (3), one or more electrochemical sensors (4), and one or more optical sensors (2). The system further comprising a controller configured in use to separately address each of the sensor elements (1) to drive the respective inductors and receive outputs of the respective sensors.
摘要翻译： 一种传感器系统，包括基板并将传感器元件（1）的阵列（7）集成到所述基板上，每个传感器元件包括一个或多个电感器（3），一个或多个电化学传感器（4）和一个或多个光学传感器 （2）。 所述系统还包括控制器，其被配置为用于单独地寻址每个所述传感器元件（1）以驱动相应的电感器并接收各个传感器的输出。
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公开(公告)号：US20130087755A1
公开(公告)日：2013-04-11
申请号：US13520930
申请日：2011-01-06
IPC分类号： H01L45/00
CPC分类号： H01L45/1633 , H01L45/08 , H01L45/1233 , H01L45/146 , H01L45/1625 , H01L45/1641 , H01L45/1666 , H01L45/1675
摘要： A method of manufacturing an electrically actuable switch and comprising: depositing a first electrode on a surface; depositing an active layer or layers on top of said first electrode; and depositing a second electrode on top of said active layer(s), wherein said step of depositing an active layer or layers is performed in an atmosphere into which a reactive gas is introduced, the partial pressure of the reactive gas being varied during the process so as to introduce dopants into the active layer in a concentration which varies across the active layer.
摘要翻译： 一种制造电致动开关的方法，包括：在表面上沉积第一电极; 在所述第一电极的顶部上沉积有源层; 以及在所述有源层的顶部上沉积第二电极，其中沉积有源层的步骤在引入反应气体的气氛中进行，反应气体的分压在该过程中变化 从而以有效层的变化浓度将有源层引入有源层。
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公开(公告)号：US20130130261A1
公开(公告)日：2013-05-23
申请号：US13813770
申请日：2011-09-06
IPC分类号： G01N27/60
CPC分类号： G01N27/60 , G01N27/127 , G01N27/3278 , G01N33/5438
摘要： A sensor comprising a memory device having a first electrode and a first chemical-sensing layer coupled to the first electrode. The chemical-sensing layer, in the presence of an analyte, is arranged to change a property of the Memristive device. The sensor can detect an analyte by providing a sample to be detected proximate the chemical sensing layer, observing the state of the memory element; and determining a property of the sample by comparing the observed state of the memory element with a previous state. The sensor is manufactured by depositing a second electrode on a surface, depositing an active layer or layers onto said second electrode, depositing a first electrode onto said active layer(s), and coupling a chemically sensitive layer to the first electrode.
摘要翻译： 传感器，包括具有第一电极和耦合到第一电极的第一化学感测层的存储器件。 在分析物存在下的化学感测层被布置成改变记忆装置的性质。 传感器可以通过在化学感测层附近提供要检测的样本来检测分析物，观察存储元件的状态; 以及通过将所述存储元件的观察状态与先前状态进行比较来确定所述样本的属性。 通过在表面上沉积第二电极来制造传感器，将活性层沉积到所述第二电极上，在第一电极上沉积第一电极，以及将化学敏感层耦合到第一电极。
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公开(公告)号：US09656020B2
公开(公告)日：2017-05-23
申请号：US13377358
申请日：2010-06-09
CPC分类号： A61M5/1723 , A61M2005/14208 , G06F19/00 , G06F19/3468
摘要： According to a first aspect of the present invention there is provided a controller for controlling a glucagon pump. The controller comprises an input 8 for receiving an input signal indicative of a measured blood glucose concentration, an output 9 for providing a pulsed glucagon pump drive signal, each pulse being arranged to cause a glucagon pump to deliver a volume of glucagon, and a processing unit 10 for setting the pulse frequency of the pump drive signal in dependence upon the input signal, such that when the input signal indicates that the measured blood glucose concentration is above a threshold concentration the pulse frequency is zero and when the input signal indicates that the measured blood glucose concentration is below the threshold concentration the pulse frequency is increased as the measured blood glucose concentration decreases.
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公开(公告)号：US09283323B2
公开(公告)日：2016-03-15
申请号：US13570525
申请日：2012-08-09
CPC分类号： A61M5/1723 , A61M5/142 , A61M2005/14208 , A61M2005/1726 , A61M2205/52 , A61M2230/201 , G06F19/00 , G06F19/3468
摘要： The present invention relates to a controller unit and methods for controlling an insulin pump. The controller unit includes a user input that receives a gain factor. The gain factor has been calculated based on historical data in relation to a patient. The controller unit includes a measurement input for receiving data representative of a measured blood glucose level for the patient. Processing logic of the controller unit is configured to apply the measured blood glucose level to a pancreatic beta-cell insulin secretion computational model to predict an insulin output level, apply the gain factor to the predicted insulin output level to determine a patient insulin deficiency level, and calculate a control signal for controlling the insulin output level of the insulin pump based on the patient insulin deficiency level. Methods are provided for optimizing the gain factor based on the historical data in relation to the patient.
摘要翻译： 本发明涉及一种用于控制胰岛素泵的控制器单元和方法。 控制器单元包括接收增益因子的用户输入。 增益因子是根据与患者相关的历史数据计算的。 控制器单元包括测量输入，用于接收表示患者的测量血糖水平的数据。 控制器单元的处理逻辑被配置为将测量的血糖水平应用于胰腺β细胞胰岛素分泌计算模型以预测胰岛素输出水平，将增益因子应用于预测的胰岛素输出水平以确定患者胰岛素缺乏水平， 并且基于患者胰岛素缺乏水平计算用于控制胰岛素泵的胰岛素输出水平的控制信号。 提供了基于与患者相关的历史数据来优化增益因子的方法。
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公开(公告)号：US20120232519A1
公开(公告)日：2012-09-13
申请号：US13377358
申请日：2010-06-09
IPC分类号： A61M5/168
CPC分类号： A61M5/1723 , A61M2005/14208 , G06F19/00 , G06F19/3468
摘要： According to a first aspect of the present invention there is provided a controller for controlling a glucagon pump. The controller comprises an input 8 for receiving an input signal indicative of a measured blood glucose concentration, an output 9 for providing a pulsed glucagon pump drive signal, each pulse being arranged to cause a glucagon pump to deliver a volume of glucagon, and a processing unit 10 for setting the pulse frequency of the pump drive signal in dependence upon the input signal, such that when the input signal indicates that the measured blood glucose concentration is above a threshold concentration the pulse frequency is zero and when the input signal indicates that the measured blood glucose concentration is below the threshold concentration the pulse frequency is increased as the measured blood glucose concentration decreases.
摘要翻译： 根据本发明的第一方面，提供了一种用于控制胰高血糖素泵的控制器。 控制器包括用于接收指示测量的血糖浓度的输入信号的输入8，用于提供脉冲胰高血糖素泵驱动信号的输出9，每个脉冲被布置成使胰高血糖素泵输送一定量的胰高血糖素，以及处理 单元10，用于根据输入信号设置泵驱动信号的脉冲频率，使得当输入信号指示所测量的血糖浓度高于阈值浓度时，脉冲频率为零，并且当输入信号指示 测量血糖浓度低于阈值浓度，脉搏频率随着测量血糖浓度的降低而增加。
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公开(公告)号：US09683260B2
公开(公告)日：2017-06-20
申请号：US13881986
申请日：2011-10-28
申请人： Pantelis Georgiou , Sam Reed , Yan Liu , Christofer Toumazou , Chung-Pei Ou
发明人： Pantelis Georgiou , Sam Reed , Yan Liu , Christofer Toumazou , Chung-Pei Ou
CPC分类号： C12Q1/6874 , C12Q1/6825 , C12Q1/6858 , G01N27/4145 , G01N27/44 , C12Q2533/101 , C12Q2565/301 , C12Q2565/607 , C12Q2565/501
摘要： An apparatus with a transducer having a first output signal and arranged to receive an electrical input. The transducer switches the first output signal between an ON and OFF state. The apparatus has a chemical sensing surface coupled to the transducer arranged to receive a chemical input. A signal generator oscillates one or more of said inputs to vary the switching point of the transducer. The oscillating input may be the chemical input and/or the electrical input. The output signal may be a pulse whose period ON or OFF is determined by the oscillating input modulated by the chemical input.
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公开(公告)号：US20130252828A1
公开(公告)日：2013-09-26
申请号：US13881986
申请日：2011-10-28
申请人： Pantelis Georgiou , Sam Reed , Yan Liu , Christofer Toumazou , Chung-Pei Ou
发明人： Pantelis Georgiou , Sam Reed , Yan Liu , Christofer Toumazou , Chung-Pei Ou
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6874 , C12Q1/6825 , C12Q1/6858 , G01N27/4145 , G01N27/44 , C12Q2533/101 , C12Q2565/301 , C12Q2565/607 , C12Q2565/501
摘要： An apparatus with a transducer having a first output signal and arranged to receive an electrical input. The transducer switches the first output signal between an ON and OFF state. The apparatus has a chemical sensing surface coupled to the transducer arranged to receive a chemical input. A signal generator oscillates one or more of said inputs to vary the switching point of the transducer. The oscillating input may be the chemical input and/or the electrical input. The output signal may be a pulse whose period ON or OFF is determined by the oscillating input modulated by the chemical input.
摘要翻译： 一种具有换能器的装置，具有第一输出信号并被布置成接收电输入。 传感器在ON和OFF状态之间切换第一个输出信号。 该装置具有耦合到换能器的化学感测表面，其布置成接收化学输入。 信号发生器振荡一个或多个所述输入以改变换能器的切换点。 振荡输入可以是化学输入和/或电输入。 输出信号可以是其周期ON或OFF由通过化学输入调制的振荡输入确定的脉冲。
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9.发明申请METHOD AND APPARATUS FOR OPTICALLY OUTPUTTING INFORMATION FROM A SEMICONDUCTOR DEVICE 审中-公开用于从半导体器件的光输出信息的方法和装置公开(公告)号：US20130077965A1
公开(公告)日：2013-03-28
申请号：US13576216
申请日：2011-02-01
IPC分类号： H04B10/08
CPC分类号： H04B10/501 , G02F1/015 , G02F2001/0156 , G02F2201/17 , G02F2202/105
摘要： A method of optically outputting information (e.g. digital data) from a semiconductor device, the method comprising: providing a semiconductor device having a semiconducting p-n junction, the p-n junction having a region of reduced free charge carrier density; applying an electrical signal to modulate the extent of the said region, the electrical signal being representative of the information to be outputted; arranging incident light to pass through at least part of the said region, such that the light is at least partially absorbed in dependence upon the modulated extent of the said region, thereby producing intensity-modulated output light; and detecting the intensity of the output light and thereby determining the outputted information. Also provided is an electro-optical assembly, a package module for mounting a semiconductor device on a printed circuit board, and an integrated circuit chip.
摘要翻译： 一种从半导体器件光学输出信息（例如数字数据）的方法，所述方法包括：提供具有半导体p-n结的半导体器件，所述p-n结具有减小的自由电荷载流子密度的区域; 施加电信号来调制所述区域的范围，所述电信号表示要输出的信息; 使入射光穿过所述区域的至少一部分，使得光根据所述区域的调制范围至少部分地被吸收，由此产生强度调制的输出光; 并检测输出光的强度，从而确定输出的信息。 还提供了一种电光学组件，用于将半导体器件安装在印刷电路板上的封装模块和集成电路芯片。
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公开(公告)号：US08114591B2
公开(公告)日：2012-02-14
申请号：US11625844
申请日：2007-01-23
CPC分类号： C12Q1/6825 , C12Q2565/607 , G01N27/4145
摘要： A method of observing reaction intermediaries during a chemical reaction and comprising detecting an electrical signal output from an ion sensitive field effect transistor exposed to said reaction, and monitoring the detected electrical signal to discriminate discrete fluctuations in the electrical signal, the discrete fluctuations indicating reaction intermediaries occurring during a chemical reaction.
摘要翻译： 一种在化学反应期间观察反应中间体的方法，包括检测暴露于所述反应的离子敏感场效应晶体管的电信号输出，并监测检测到的电信号以区分电信号中的离散波动，指示反应中间体的离散波动 在化学反应期间发生。
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