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公开(公告)号：US4519973A
公开(公告)日：1985-05-28
申请号：US519937
申请日：1983-08-03
申请人： Patrick T. Cahalan , Allan H. Jevne , Eric J. Fogt
发明人： Patrick T. Cahalan , Allan H. Jevne , Eric J. Fogt
IPC分类号： G01N27/333 , G01N27/40 , B29D3/00 , A61B5/00 , G01N27/46
CPC分类号： G01N27/40 , G01N27/3335 , Y10T29/49117
摘要： An improved method for producing ion-selective membranes having a desired shape and of a desired plastic, for incorporation in ion-sensing electrodes, and the electrodes incorporating these membranes. This method allows the use of preformed polymeric members having the desired shape to produce ion-selective membranes, allowing simplified production of ion-sensing electrodes, as well as combination ion-sensing and reference electrodes.
摘要翻译： 一种用于生产具有所需形状和期望塑料的离子选择性膜的改进方法，用于结合到离子感测电极中，以及掺入这些膜的电极。 该方法允许使用具有所需形状的预成型聚合物构件来产生离子选择膜，从而允许简化离子感测电极的生产，以及组合的离子感测和参比电极。
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公开(公告)号：US4694834A
公开(公告)日：1987-09-22
申请号：US846388
申请日：1986-03-31
IPC分类号： G01N27/414 , A61B5/00
CPC分类号： G01N27/4141
摘要： A simplified gas sensor which includes a pH sensitive transducer having a gate-insulated field effect transistor (FET) structure. The gas sensor is particularly adapted to detect carbon dioxide in fluids.
摘要翻译： 一种简化的气体传感器，其包括具有栅极绝缘场效应晶体管（FET）结构的pH敏感传感器。 气体传感器特别适用于检测流体中的二氧化碳。
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公开(公告)号：US08529525B2
公开(公告)日：2013-09-10
申请号：US13357594
申请日：2012-01-24
申请人： Martin T. Gerber , Eric J. Fogt
发明人： Martin T. Gerber , Eric J. Fogt
IPC分类号： A61M37/00
CPC分类号： A61M39/0208 , A61M2039/0229 , A61M2039/0235
摘要： The invention relates to implantable vascular access ports that can release agents such as antibiotics, anti-thrombogenics and anti-proliferatives. The invention also relates to ports having locking mechanisms that prevent accidental disengagement, and structures that facilitate surgical implantation and provide for long-term stability and use of the port.
摘要翻译： 本发明涉及可以释放诸如抗生素，抗血栓形成剂和抗增殖剂的药剂的可植入血管进入口。 本发明还涉及具有防止意外分离的锁定机构的端口以及便于手术植入并提供端口的长期稳定性和使用的结构。
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公开(公告)号：US4600495A
公开(公告)日：1986-07-15
申请号：US765757
申请日：1985-08-15
申请人： Eric J. Fogt
发明人： Eric J. Fogt
IPC分类号： B29D23/00 , B29D99/00 , G01N27/28 , G01N27/333 , G01N27/46
CPC分类号： G01N27/3335 , B29D23/00 , B29D99/005 , B29K2021/00 , B29K2027/06 , B29K2075/00 , B29L2031/755
摘要： An improved flow through ion sensing electrode and a method for producing it. The electrode is formed of bilumen plastic tubing using one lumen as the sample path and the other lumen as a sensing chamber. By permeating a portion of the tubing with an ion selective material, an ion selective membrane integral with the chamber wall is produced. A preferred embodiment also incorporates a reference electrode.
摘要翻译： 通过离子感测电极的改进的流动及其制造方法。 电极由使用一个腔作为样品路径和另一个腔作为感测室的柏油塑料管形成。 通过用离子选择性材料渗透管道的一部分，产生与室壁一体的离子选择膜。 优选实施例还包括参考电极。
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公开(公告)号：US5282466A
公开(公告)日：1994-02-01
申请号：US770672
申请日：1991-10-03
CPC分类号： A61B5/14535 , A61B5/14557 , A61B5/1495 , G01N21/274 , A61B2560/0233 , G01N2201/1244 , G01N2201/1281
摘要： A system for disabling an oximetric device when radiation-carrying channels are exposed to excess ambient radiation is disclosed. It includes a transmitter channel adjacent the sample to be measured, means for isolating the channel from the sample so that it does not carry radiation reflected from or transmitted through the sample, a detector for receiving the transmitted signal, if any, and means for disabling the output in response to the transmitted signal. Preferably, the transmitter channel runs parallel to other transmitter channels in the device, and is isolated from undue ambient light. The system preferably includes means for determining when the second transmitted signal exceeds background noise and the output is disabled when the second transmitted signal exceeds background noise. In general, the sample is a fluid, usually blood, passing through a cuvette adjacent the fiber-optic channels, the cuvette defining an area of radiation absorption adjacent the transmitter channel so that the transmitter does not carry reflected or transmitted radiation from the sample. Also disclosed is a fiber-optic sensor for measuring components of a composition by detecting transmitted or reflected, usually reflected, radiation including such a system, and the cuvette therefore. Finally, a method of disabling the output of an oximetric device when the fiber-optic channels are exposed to undue ambient radiation is disclosed.
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公开(公告)号：US4444193A
公开(公告)日：1984-04-24
申请号：US338274
申请日：1982-01-11
CPC分类号： G01N33/84 , A61B5/4266 , G01N33/526 , Y10T436/193333
摘要： An absorbent quantitative test device in the form of a flat patch. When placed on the skin of a subject; the device collects a fixed volume of sweat. It is particularly intended to be used in screen testing for cystic fibrosis by measuring the chloride level in sweat and providing a visual indication when the level is in excess of a predetermined concentration. A fill tab indicator undergoes a color change when the fixed volume of sweat has been collected signifying completion of the test. The device includes two concentric circular reaction areas of chemically treated absorbent paper or the like. The sweat sample is introduced into the device at the center of the first or inner circular reaction area which contains a chemical composition capable of reacting with all chloride in the sweat sample below a predetermined concentration value to screen out that amount of chloride. A second or outer ring-shaped reaction area contains a chemical composition which indicates a color change for any chloride reaching it in excess of the predetermined concentration value. The color change in the outer ring-shaped portion thereby provides a quantitative indication of the presence of a concentration of chloride in the subject' s sweat in excess of the predetermined concentration level.
摘要翻译： 呈贴片形式的吸收性定量测试装置。 当放置在受试者的皮肤上时; 该装置收集固定体积的汗水。 特别旨在通过测量汗液中的氯化物含量并在水平超过预定浓度时提供视觉指示来用于囊性纤维化的屏幕测试。 当收集的固定体积的汗水表示测试完成时，填充标签指示器会发生颜色变化。 该装置包括化学处理的吸收纸等的两个同心圆形反应区域。 汗液样品在第一或内部圆形反应区域的中心被引入到装置中，该区域包含能够使低于预定浓度值的汗液样品中的所有氯化物反应的化学组成，以筛除该量的氯化物。 第二个或外部环形反应区域包含化学组成，其指示任何达到超过预定浓度值的氯化物的颜色变化。 外环形部分中的颜色变化由此提供了在受试者的汗中超过预定浓度水平的氯化物浓度的定量指示。
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公开(公告)号：US5341804A
公开(公告)日：1994-08-30
申请号：US977978
申请日：1992-11-18
CPC分类号： A61B5/14535 , A61B5/14557 , A61B5/1495 , G01N21/274 , A61B2560/0233 , G01N2201/1244 , G01N2201/1281
摘要： A system for disabling an oximetric device when radiation-carrying channels are exposed to excess ambient radiation is disclosed. It includes a transmitter channel adjacent the sample to be measured, means for isolating the channel from the sample so that it does not carry radiation reflected from or transmitted through the sample, a detector for receiving the transmitted signal, if any, and means for disabling the output in response to the transmitted signal. Preferably, the transmitter channel runs parallel to other transmitter channels in the device, and is isolated from undue ambient light. The system preferably includes means for determining when the second transmitted signal exceeds background noise and the output is disabled when the second transmitted signal exceeds background noise. In general, the sample is a fluid, usually blood, passing through a cuvette adjacent the fiber-optic channels, the cuvette defining an area of radiation absorption adjacent the transmitter channel so that the transmitter does not carry reflected or transmitted radiation from the sample. Also disclosed is a fiber-optic sensor for measuring components of a composition by detecting transmitted or reflected, usually reflected, radiation including such a system, and the cuvette therefore. Finally, a method of disabling the output of an oximetric device when the fiber-optic channels are exposed to undue ambient radiation is disclosed.
摘要翻译： 公开了一种当辐射承载通道暴露于过量环境辐射时使得血压测定装置失效的系统。 它包括与要测量的样本相邻的发射机信道，用于将信道与样本隔离的装置，使得其不携带从样本反射或透射的辐射，用于接收发射信号的检测器（如果有的话）以及用于禁用的装置 响应于所发送的信号的输出。 优选地，发射机信道平行于设备中的其他发射机信道，并且与不适当的环境光隔离。 系统优选地包括用于确定第二发射信号何时超过背景噪声的装置，并且当第二发射信号超过背景噪声时输出被禁用。 通常，样品是流体，通常为血液，通过与光纤通道相邻的比色杯，比色皿限定了邻近发射器通道的辐射吸收区域，使得发射器不携带来自样品的反射或透射的辐射。 还公开了一种用于通过检测包括这种系统的透射或反射的，通常被反射的辐射来测量组合物的组分的光纤传感器，以及因此的比色皿。 最后，公开了当光纤通道暴露于不适当的环境辐射时禁用血压计的输出的方法。
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公开(公告)号：US4565665A
公开(公告)日：1986-01-21
申请号：US519934
申请日：1983-08-03
申请人： Eric J. Fogt
发明人： Eric J. Fogt
IPC分类号： B29D23/00 , B29D99/00 , G01N27/28 , G01N27/333 , G01N27/46
CPC分类号： B29D23/00 , B29D99/005 , G01N27/28 , G01N27/3335 , B29K2021/00 , B29K2027/06 , B29K2075/00 , B29L2031/755
摘要： An improved flow through ion sensing electrode and a method for producing it. The electrode is formed of bilumen plastic tubing using one lumen as the sample path and the other lumen as a sensing chamber. By permeating a portion of the tubing with an ion selective material, an ion selective membrane integral with the chamber wall is produced. A preferred embodiment also incorporates a reference electrode.
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公开(公告)号：US20120245536A1
公开(公告)日：2012-09-27
申请号：US13357594
申请日：2012-01-24
申请人： Martin T. Gerber , Eric J. Fogt
发明人： Martin T. Gerber , Eric J. Fogt
IPC分类号： A61M5/00
CPC分类号： A61M39/0208 , A61M2039/0229 , A61M2039/0235
摘要： The invention relates to implantable vascular access ports that can release agents such as antibiotics, anti-thrombogenics and anti-proliferatives. The invention also relates to ports having locking mechanisms that prevent accidental disengagement, and structures that facilitate surgical implantation and provide for long-term stability and use of the port.
摘要翻译： 本发明涉及可以释放诸如抗生素，抗血栓形成剂和抗增殖剂的药剂的可植入血管进入口。 本发明还涉及具有防止意外分离的锁定机构的端口以及便于手术植入并提供端口的长期稳定性和使用的结构。
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公开(公告)号：US20100196439A1
公开(公告)日：2010-08-05
申请号：US12520035
申请日：2007-12-20
申请人： Michael Theodore Beck , Deon Bezuidenhout , Kelvin Bonnema , Kimberly A. Chaffin , Neil Davies , Brian C.A. Fernandes , Eric J. Fogt , Eric A. Grovender , Robert Cushing Hamlen , Matthew Jolly , Eamonn J. McAndrew , Syamasundar V. Pakala , William P. VanAntwerp , Peter P. Zilla , Edouard A. Koullick
发明人： Michael Theodore Beck , Deon Bezuidenhout , Kelvin Bonnema , Kimberly A. Chaffin , Neil Davies , Brian C.A. Fernandes , Eric J. Fogt , Eric A. Grovender , Robert Cushing Hamlen , Matthew Jolly , Eamonn J. McAndrew , Syamasundar V. Pakala , William P. VanAntwerp , Peter P. Zilla , Edouard A. Koullick
CPC分类号： A61L27/38 , A61F2/022 , A61L27/3616 , A61L27/54 , A61L2300/414 , A61L2300/416 , A61L2300/426 , A61L2300/434
摘要： Various methods and devices are provided for providing therapy to a living body. In one embodiment, an implanted permeable container has living cells provided therein, and various nutrients and/or agents are provided into the container to promote cell life.
摘要翻译： 提供用于向生物体提供治疗的各种方法和装置。 在一个实施例中，植入的可渗透容器具有设置在其中的活细胞，并且向容器提供各种营养物和/或试剂以促进细胞寿命。
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