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公开(公告)号：US20060199816A1
公开(公告)日：2006-09-07
申请号：US11365053
申请日：2006-03-01
IPC分类号： A61K31/538 , A61K31/4709 , A61K31/453 , A61K31/445
CPC分类号： C07D211/96 , A61K31/445 , A61K31/453 , A61K31/4709 , A61K31/538 , C07D401/06 , C07D401/12 , C07D409/12 , C07D409/14 , C07D487/08
摘要： Provided herein are compounds of the formula (1): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要翻译： 本文提供了式（1）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病，例如II型糖尿病和代谢综合征。
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公开(公告)号：US20070167622A1
公开(公告)日：2007-07-19
申请号：US11650645
申请日：2007-01-08
IPC分类号： C07D417/02
CPC分类号： C07D277/56 , C07D417/06 , C07D417/14
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病，例如II型糖尿病和代谢综合征。
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公开(公告)号：US07645773B2
公开(公告)日：2010-01-12
申请号：US11650645
申请日：2007-01-08
IPC分类号： A61K31/4709 , A61K31/427 , C07D403/02 , C07D215/00 , C07D277/20
CPC分类号： C07D277/56 , C07D417/06 , C07D417/14
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病，例如II型糖尿病和代谢综合征。
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公开(公告)号：US20060223852A1
公开(公告)日：2006-10-05
申请号：US11395763
申请日：2006-03-31
申请人： Paul Gillespie , Robert Goodnow , Qiang Zhang
发明人： Paul Gillespie , Robert Goodnow , Qiang Zhang
IPC分类号： A61K31/4709 , A61K31/454 , C07D409/14
CPC分类号： C07D401/06 , C07D231/14 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/14 , C07D409/14
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病，例如II型糖尿病和代谢综合征。
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公开(公告)号：US20120230951A1
公开(公告)日：2012-09-13
申请号：US13414854
申请日：2012-03-08
申请人： Muzaffar Alam , Steven Joseph Berthel , John A. Brinkman , Ronald Charles Hawley , Hongju Li , Wylie Solang Palmer , Sherrie Pietranico-Cole , Ramakanth Sarabu , Mark Smith , Sung-Sau So , Lin Yi , Yansheng Zhai , Qiang Zhang , Shu-Hai Zhao
发明人： Muzaffar Alam , Steven Joseph Berthel , John A. Brinkman , Ronald Charles Hawley , Hongju Li , Wylie Solang Palmer , Sherrie Pietranico-Cole , Ramakanth Sarabu , Mark Smith , Sung-Sau So , Lin Yi , Yansheng Zhai , Qiang Zhang , Shu-Hai Zhao
IPC分类号： A61K31/55 , A61P37/02 , A61P31/14 , A61K38/21 , C07D487/06 , A61K31/551
CPC分类号： C07D487/06 , A61K31/55 , A61K31/551 , A61K45/06 , C07D519/00 , A61K2300/00
摘要： The present invention provides compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
摘要翻译： 本发明提供用于治疗丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 还公开了含有这些化合物的药物组合物和使用这些化合物治疗HCV感染的方法。
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公开(公告)号：US08188098B2
公开(公告)日：2012-05-29
申请号：US12433921
申请日：2009-05-01
申请人： Shawn David Erickson , Paul Gillespie , Kevin Richard Guertin , Prabha Saba Karnachi , Kyungjin Kim , Chun Ma , Warren William McComas , Sherrie Lynn Pietranico-Cole , Lida Qi , Jefferson Wright Tilley , Qiang Zhang
发明人： Shawn David Erickson , Paul Gillespie , Kevin Richard Guertin , Prabha Saba Karnachi , Kyungjin Kim , Chun Ma , Warren William McComas , Sherrie Lynn Pietranico-Cole , Lida Qi , Jefferson Wright Tilley , Qiang Zhang
IPC分类号： A01N43/90 , A61K31/519 , C07D487/00
CPC分类号： C07D487/04
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗代谢疾病和病症，例如II型糖尿病。
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7.发明授权Adamantyl-pyrazole carboxamides as inhibitors of 11β-hdroxysteroid dehydrogenase 有权金刚烷基 - 吡唑甲酰胺作为11＆amp; - 类固醇脱氢酶的抑制剂公开(公告)号：US07728029B2
公开(公告)日：2010-06-01
申请号：US11717996
申请日：2007-03-14
申请人： Kevin William Anderson , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow, Jr. , Kevin Richard Guertin , Nancy-Ellen Haynes , Michael Paul Myers , Sherrie Lynn Pietranico-Cole , Lida Qi , Pamela Loreen Rossman , Nathan Robert Scott , Kshitij Chhabilbhai Thakkar , Jefferson Wright Tilley , Qiang Zhang
发明人： Kevin William Anderson , Nader Fotouhi , Paul Gillespie , Robert Alan Goodnow, Jr. , Kevin Richard Guertin , Nancy-Ellen Haynes , Michael Paul Myers , Sherrie Lynn Pietranico-Cole , Lida Qi , Pamela Loreen Rossman , Nathan Robert Scott , Kshitij Chhabilbhai Thakkar , Jefferson Wright Tilley , Qiang Zhang
IPC分类号： A61K31/4155 , A61K31/415 , A61K31/454 , A61K31/5377 , C07D231/14 , C07D401/04 , C07D413/04 , C07D403/04
CPC分类号： C07D403/04 , C07D231/12 , C07D231/16 , C07D231/38 , C07D401/04 , C07D403/02 , C07D407/14 , C07D413/04 , C07D417/04
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病，例如II型糖尿病和代谢综合征。
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公开(公告)号：US20090286812A1
公开(公告)日：2009-11-19
申请号：US12433921
申请日：2009-05-01
申请人： Shawn David Erickson , Paul Gillespie , Kevin Richard Guertin , Prabha Saba Karnachi , Kyungjin Kim , Chun Ma , Warren William McComas , Sherrie Lynn Pietranico-Cole , Lida Qi , Jefferson Wright Tilley , Qiang Zhang
发明人： Shawn David Erickson , Paul Gillespie , Kevin Richard Guertin , Prabha Saba Karnachi , Kyungjin Kim , Chun Ma , Warren William McComas , Sherrie Lynn Pietranico-Cole , Lida Qi , Jefferson Wright Tilley , Qiang Zhang
IPC分类号： A61K31/519 , C07D487/04 , A61P3/10
CPC分类号： C07D487/04
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of metabolic diseases and disorders such as, for example, type II diabetes mellitus.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗代谢疾病和病症，例如II型糖尿病。
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公开(公告)号：US07345058B2
公开(公告)日：2008-03-18
申请号：US11395763
申请日：2006-03-31
IPC分类号： A61K31/4709 , A61K31/4155 , A61K31/415 , C07D215/08 , C07D231/12
CPC分类号： C07D401/06 , C07D231/14 , C07D401/14 , C07D403/04 , C07D403/06 , C07D403/14 , C07D409/14
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病，例如II型糖尿病和代谢综合征。
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公开(公告)号：US07790711B2
公开(公告)日：2010-09-07
申请号：US12172389
申请日：2008-07-14
申请人： Paul Gillespie , Kevin Richard Guertin , Lida Qi , Qiang Zhang
发明人： Paul Gillespie , Kevin Richard Guertin , Lida Qi , Qiang Zhang
IPC分类号： A61K31/55 , A61K31/4439 , A61K31/4155 , A61P3/10 , C07D231/02 , C07D401/06 , C07D413/02 , C07D401/04
CPC分类号： C07D231/38
摘要： Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.
摘要翻译： 本文提供式（I）的化合物及其药学上可接受的盐，其中取代基如说明书中公开的那些。 这些化合物和含有它们的药物组合物可用于治疗疾病，例如II型糖尿病和代谢综合征。
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