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    Methods and apparatus to treat and prevent atrial tachyarrhythmias
    6.
    发明授权
    Methods and apparatus to treat and prevent atrial tachyarrhythmias 失效
    治疗和预防房性快速性心律失常的方法和装置

    公开(公告)号：US08311620B2

    公开(公告)日：2012-11-13

    申请号：US11895025

    申请日：2007-08-22

    申请人： Jihong Qu ,  Haris J. Sih ,  Mark Schwartz ,  Prashant Sinha

    发明人： Jihong Qu ,  Haris J. Sih ,  Mark Schwartz ,  Prashant Sinha

    IPC分类号： A61B5/04 ,  A61K9/22

    CPC分类号： A61N1/3621 ,  A61M5/14276 ,  A61N1/0568 ,  A61N1/0587 ,  A61N1/3962

    摘要： The invention provides a cardiac rhythm management system which includes a tachyarrhythmia detection and classification circuit programmed to detect and classify a tachyarrhythmia, a biologic therapy delivery device configured to deliver or regulate an expression cassette suitable for terminating or preventing atrial fibrillation (AF), and a control circuit coupled to the tachyarrhythmia detection and classification circuit and the biologic therapy delivery device. Also provided is an implantable medical device for use in a body having a cardiovascular system, which includes an implantable device body including at least a cardiovascular portion configured to be in the cardiovascular system, and an expression cassette incorporated into the cardiovascular portion of the implantable device body, the expression cassette selected to express a gene product that terminates or prevents AF. Further provided are methods which employ particular expression cassettes to prevent, inhibit or treat AF.

    摘要翻译： 本发明提供一种心律管理系统，其包括程序化以检测和分类快速性心律失常的快速性心律失常检测和分类电路，构造成递送或调节适于终止或预防心房颤动（AF）的表达盒的生物治疗递送装置，以及 耦合到快速心律失常检测和分类电路的控制电路和生物治疗递送装置。 还提供了一种用于具有心血管系统的身体的可植入医疗装置，其包括可植入装置主体，该可植入装置主体至少包括构造成在心血管系统中的心血管部分，以及结合到可植入装置的心血管部分中的表达盒 身体，选择表达终止或预防AF的基因产物的表达盒。 还提供了采用特定表达盒来预防，抑制或治疗房颤的方法。

    LED light bar for optical traffic control systems
    7.
    发明授权
    LED light bar for optical traffic control systems 有权
    用于光学交通控制系统的LED灯条

    公开(公告)号：US08072346B2

    公开(公告)日：2011-12-06

    申请号：US12421210

    申请日：2009-04-09

    申请人： Timothy Hall ,  Mark Schwartz

    发明人： Timothy Hall ,  Mark Schwartz

    IPC分类号： G08B5/22

    CPC分类号： G08G1/087

    摘要： Various approaches for activating a traffic control preemption system. A light bar includes a support structure and a plurality of LED modules individually mounted on the support structure. Each LED module includes a plurality of LED groups, and in at least one of the plurality of LED modules, at least one LED group in the module is an infrared (IR) LED group, and at least one LED group in the module is a visible light LED group. A controller is coupled to each module. The controller is configured to trigger an IR light pulse pattern at a first level of IR radiant power from the at least one IR LED group. The pulse pattern and first level of IR radiant power activate preemption in a traffic control preemption system.

    摘要翻译： 用于激活流量控制抢占系统的各种方法。 灯条包括支撑结构和分别安装在支撑结构上的多个LED模块。 每个LED模块包括多个LED组，并且在所述多个LED模块中的至少一个中，所述模块中的至少一个LED组是红外（IR）LED组，并且所述模块中的至少一个LED组是 可见光LED组。 控制器耦合到每个模块。 控制器被配置为以至少一个IR LED组的IR辐射功率的第一水平触发IR光脉冲模式。 脉冲模式和红外辐射功率的第一级激活流量控制抢占系统中的抢占。

    OPTICAL TRAFFIC CONTROL SYSTEM WITH BURST MODE LIGHT EMITTER
    8.
    发明申请
    OPTICAL TRAFFIC CONTROL SYSTEM WITH BURST MODE LIGHT EMITTER 有权
    具有冲击模式光发射器的光学交通控制系统

    公开(公告)号：US20110068951A1

    公开(公告)日：2011-03-24

    申请号：US12142421

    申请日：2008-06-19

    申请人： Mark Schwartz ,  Charles Meyer

    发明人： Mark Schwartz ,  Charles Meyer

    IPC分类号： G08G1/087

    CPC分类号： G08G1/087

    摘要： Various approaches for a traffic control preemption system that includes a receiver, a light emitter, and control circuitry. The receiver includes a photodetector and circuitry that produces a number of electrical pulses in response to each detected light pulse. For each detected light pulse the number of electrical pulses represents a level of radiant power of the light pulse, and a threshold number of electrical pulses and an activation frequency at which the threshold number of electrical pulses is repeated activates preemption. The control circuitry is coupled to the light emitter and controls the light emitter to emit bursts of light pulses. Each burst includes at least two light pulses and a frequency of light pulses in each burst and a frequency of the bursts cause the receiver to produce at least the threshold number of electrical pulses at the activation frequency and activate the preemption.

    摘要翻译： 用于包括接收器，发光器和控制电路的交通控制抢占系统的各种方法。 接收器包括光电检测器和响应于每个检测到的光脉冲而产生多个电脉冲的电路。 对于每个检测到的光脉冲，电脉冲数表示光脉冲的辐射功率的水平，并且电脉冲的阈值数量和重复阈值电脉冲的激活频率激活抢占。 控制电路耦合到光发射器并且控制光发射器发射一束光脉冲。 每个脉冲串包括至少两个光脉冲和每个脉冲串中的光脉冲的频率，并且脉冲串的频率使接收器产生至少在激活频率处的阈值数量的电脉冲并激活抢占。

    Methods and apparatus to treat and prevent atrial tachyarrhythmias
    9.
    发明申请
    Methods and apparatus to treat and prevent atrial tachyarrhythmias 失效
    治疗和预防房性快速性心律失常的方法和装置

    公开(公告)号：US20090054943A1

    公开(公告)日：2009-02-26

    申请号：US11895025

    申请日：2007-08-22

    申请人： Jihong Qu ,  Haris J. Sih ,  Mark Schwartz ,  Prashant Sinha

    发明人： Jihong Qu ,  Haris J. Sih ,  Mark Schwartz ,  Prashant Sinha

    IPC分类号： A61N1/05 ,  A61N1/18 ,  A61N1/362

    CPC分类号： A61N1/3621 ,  A61M5/14276 ,  A61N1/0568 ,  A61N1/0587 ,  A61N1/3962

    摘要： The invention provides a cardiac rhythm management system which includes a tachyarrhythmia detection and classification circuit programmed to detect and classify a tachyarrhythmia, a biologic therapy delivery device configured to deliver or regulate an expression cassette suitable for terminating or preventing atrial fibrillation (AF), and a control circuit coupled to the tachyarrhythmia detection and classification circuit and the biologic therapy delivery device. Also provided is an implantable medical device for use in a body having a cardiovascular system, which includes an implantable device body including at least a cardiovascular portion configured to be in the cardiovascular system, and an expression cassette incorporated into the cardiovascular portion of the implantable device body, the expression cassette selected to express a gene product that terminates or prevents AF. Further provided are methods which employ particular expression cassettes to prevent, inhibit or treat AF.

    摘要翻译： 本发明提供一种心律管理系统，其包括程序化以检测和分类快速性心律失常的快速性心律失常检测和分类电路，构造成递送或调节适于终止或预防心房颤动（AF）的表达盒的生物治疗递送装置，以及 耦合到快速心律失常检测和分类电路的控制电路和生物治疗递送装置。 还提供了一种用于具有心血管系统的身体的可植入医疗装置，其包括可植入装置主体，该可植入装置主体至少包括构造成在心血管系统中的心血管部分，以及结合到可植入装置的心血管部分中的表达盒 身体，选择表达终止或预防AF的基因产物的表达盒。 还提供了采用特定表达盒来预防，抑制或治疗房颤的方法。