摘要:
A method for reducing or substantially preventing formation of a trisulfide derivative of a polypeptide in a liquid medium containing the polypeptide ijn question comprises stripping the liquid medium with a gas, suitably a chemically unreactive gas such as nitrogen or argon.
摘要:
A method for reducing or substantially preventing formation of a trisulfide derivative of a polypeptide in a liquid medium containing the polypeptide ijn question comprises stripping the liquid medium with a gas, suitably a chemically unreactive gas such as nitrogen or argon.
摘要:
A method for reducing or substantially preventing formation of a trisulfide derivative of a polypeptide in a liquid medium containing the polypeptide ijn question comprises stripping the liquid medium with a gas, suitably a chemically unreactive gas such as nitrogen or argon.
摘要:
The invention concerns a hydraulic valve arrangement (1) with a supply connection arrangement comprising a high-pressure connection (P) and a low-pressure connection (T), a working connection arrangement comprising two working connections (A, B), which can be connected to a motor (4), a directional valve arrangement (5) located between the supply connection arrangement (P, T) and the working connection arrangement (A, B), and a compensation valve (15) acted upon in a first activation direction by a pressure in a first pressure chamber (33), which is connected to a load-sensing pipe (LS), and, if required, by a spring (32), and in a second activation direction opposite to the first activation direction by a pressure downstream of the directional valve arrangement (5), said pressure acting in a second pressure chamber (34), the compensation valve (15) having an inlet (14) and an outlet (19). In connection with a post-compensated valve, it is endeavoured to adjust the load pressures at the working connections (A, B) in dependence of the direction. For this purpose, each working connection (A, B) is connected to a control system, which amplifies the effect of the pressure in the first pressure chamber (33) on the compensation valve (15) in dependence of a pressure ruling at the working connection (A, B).
摘要:
A hydraulic valve system (1) has a supply connection arrangement having a high-pressure connection (P) and a low-pressure connection (T), a working connection arrangement, having two working connections (A, B) connectable with a motor (2), with a directional valve (4), which is arranged between the supply connection arrangement (P, T) and the working connection arrangement (A, B), and with a compensation valve (8), which is acted upon in a first operation direction by a spring (22) and a pressure in a pressure chamber (23), which is connected with a load-sensing line (LS), and in a second operation direction, which is opposite to the first operation direction, by a pressure at the directional valve (4).
摘要:
A hydraulic valve arrangement includes a control valve (3), which, in a first operating position (5), connects a motor connection (21) with a pump connection, in a second operating position (6), connects a motor connection with a tank connection, and, in a locking position (4), disconnects the motor connection (21) from the pump and tank connection. A locking valve (19) is coupled between the control valve (3) and the motor connection (21), dividing the motor line (22) into a first section (23) allocated to the control valve (3) and a second section (24) allocated to the motor connection (21). For the locking valve (19), a pressure release valve (20) in the shape of a seated valve is provided that is fixed to the housing thereby improving control accuracy.
摘要:
A desired protein having the formula: A-B-C-P wherein a) A is Lys or Arg, and B and C are arbitrary amino acids, or b) A is an arbitrary amino acid different from Pro, Lys and Arg, and B and/or C is Pro, is produced from a biosynthetically formed amino acid extended protein having the formula: X-A-B-C-P wherein A, B, C and P are as defined above, and X is an amino acid sequence with an even number of amino acids, of which the first one, seen from the N-terminal end, is different from Lys and Arg, all other uneven amino acids are different from Pro, Lys and Arg, and all even amino acids are different from Pro, by reaction with the enzyme dipeptidyl aminopeptidase (DAP I). The desired protein is obtained in a pure state. Thus, e.g. hGH without content of Met-hGH may be produced by the process.
摘要翻译:具有下式的所需蛋白质:ABCP其中a)A是Lys或Arg,B和C是任意氨基酸,或b)A是不同于Pro,Lys和Arg的任意氨基酸,B和/或C是 Pro是由具有下式的生物合成形式的氨基酸延伸蛋白产生的:XABCP其中A,B,C和P如上定义,X是具有偶数氨基酸的氨基酸序列,其中第一个 从N末端看,与Lys和Arg不同,所有其他不均匀的氨基酸与Pro,Lys和Arg不同,所有偶联的氨基酸与Pro不同,通过与酶二肽基氨基肽酶(DAP I )。 在纯状态下获得所需的蛋白质。 因此,例如 可以通过该过程产生没有Met-hGH含量的hGH。
摘要:
The invention relates to a steering control unit for a bidirectional servomotor which is connectable to steerable wheels. A steering wheel controlled quantity setting unit of a known type has ports connectable to a pump and a return tank and two control ports through which metered quantities of fluid flow to opposite sides of the servomotor and to other parts of the apparatus for actuating the servomotor. A directional control valve for selectivity directing pressurized fluid from a power circuit to opposite sides of the servomotor is controlled by a control circuit containing the setting unit. A utility valve having pressure regulating and control and power valve capabilities is provided. In cases wherein the quantity setting apparatus is remotely located from the regulating valve the length of the signal channels add to the reaction time. Such reaction time is reduced herein by connecting the metering throttle as a fixed throttle between the regulating valve and quantity setting apparatus so that the regulating valve feeds a substantially constant quantity to the control cicuit, and that the quantity setting apparatus comprises a short circuit path to the tank which closes with an increase in the quantity.
摘要:
The invention relates to hydraulic control apparatus for a servomotor of the type utilized for vehicle steering systems. Such apparatus has a control circuit controlled by a manually operated device such as a steering wheel and a power circuit connected between the servomotor and a power source such as a hydraulic pump. The power circuit includes resetting apparatus for throttling the return flow branch in a manner so that forces applied to the servomotor in the same direction as actuation are absorbed with a minimum of reactionary movement by the valves on the return flow side of the apparatus.
摘要:
The invention concerns a hydraulic valve arrangement (1) with at least two valve modules (2-6), each having a supply channel arrangement with a high-pressure channel (9) and a low-pressure channel (15), a working connection arrangement with at least one working connection (A, B), one directional valve arrangement (16) between the supply channel arrangement (9, 15) and the working connection arrangement (A, B) and a compensation arrangement (19), which is acted upon by a pressure in a load-sensing arrangement. It is endeavored to increase the number of control possibilities. For this purpose, the load-sensing arrangement of at least one valve module (2-6) has a pressure influencing arrangement (25-29) that differs from a pressure influencing arrangement (25-29) of a load sensing arrangement of another valve module (2-6).