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公开(公告)号:US20130004460A1
公开(公告)日:2013-01-03
申请号:US13574970
申请日:2011-01-25
申请人: Pierre Weiss , Jerome Guicheux , Gildas Rethore , Emile Rederstorff , Samia Laib
发明人: Pierre Weiss , Jerome Guicheux , Gildas Rethore , Emile Rederstorff , Samia Laib
IPC分类号: A61K35/00 , A61K38/16 , A61K31/7088 , A61K31/732 , A61K31/722 , A61K31/728 , A61K31/70 , A61K38/39 , A61K38/17 , A61K38/07 , A61K31/715 , A61K31/717 , A61P19/04 , A61P19/08 , A61P9/00 , A61P17/00 , A61K38/02
CPC分类号: G01N33/54353 , A61K9/06 , A61K47/36 , C07F7/1804 , C08B15/05 , C08B37/003 , C08B37/0045 , C08B37/0072 , C08G18/10 , C08G18/12 , C08G18/6446 , C08G18/718 , C08G2210/00 , C08H1/00 , C08H1/06 , C08J3/075 , C08J3/246 , C08J2300/108 , C08J2305/06 , C08J2305/08 , C08L1/08 , C08L1/28 , C08L5/06 , C08L5/08 , C08L89/00 , C08L89/06 , C08L2203/02 , C08G18/3275 , C08L2666/26
摘要: The invention concerns: a silylated biomolecule having the following formula (I): the process for the preparation of a silylated biomolecule of formula (I), the use of a silylated biomolecule of formula (I) to functionalize the surface of a support, a process for the preparation of a hydrogel by use of a silylated biomolecule of formula (I), the hydrogel obtainable by said process, said hydrogel as a biological tissue substitute, a composition comprising said hydrogel in a pharmaceutically acceptable vehicle, said composition for the release of active principle.
摘要翻译: 本发明涉及:具有下式(I)的甲硅烷基化生物分子:制备式(I)的甲硅烷基化生物分子的方法,使用式(I)的甲硅烷基化生物分子将载体的表面官能化, 用于通过使用式(I)的甲硅烷基化生物分子制备水凝胶的方法,可通过所述方法获得的水凝胶,所述水凝胶作为生物组织替代物,在药学上可接受的载体中包含所述水凝胶的组合物,所述用于释放的组合物 的积极原则。
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公开(公告)号:US09285360B2
公开(公告)日:2016-03-15
申请号:US13574970
申请日:2011-01-25
申请人: Pierre Weiss , Jerome Guicheux , Gildas Rethore , Emile Rederstorff , Samia Laib
发明人: Pierre Weiss , Jerome Guicheux , Gildas Rethore , Emile Rederstorff , Samia Laib
IPC分类号: C07F7/18 , G01N33/543 , A61K9/06 , A61K47/36 , C08B15/05 , C08B37/08 , C08B37/00 , C08G18/10 , C08G18/12 , C08G18/64 , C08G18/71 , C08J3/075 , C08J3/24 , C08L5/06 , C08L5/08 , C08L89/00 , C08L89/06 , C08H1/00 , C08H1/06 , C08L1/28 , C08L1/08
CPC分类号: G01N33/54353 , A61K9/06 , A61K47/36 , C07F7/1804 , C08B15/05 , C08B37/003 , C08B37/0045 , C08B37/0072 , C08G18/10 , C08G18/12 , C08G18/6446 , C08G18/718 , C08G2210/00 , C08H1/00 , C08H1/06 , C08J3/075 , C08J3/246 , C08J2300/108 , C08J2305/06 , C08J2305/08 , C08L1/08 , C08L1/28 , C08L5/06 , C08L5/08 , C08L89/00 , C08L89/06 , C08L2203/02 , C08G18/3275 , C08L2666/26
摘要: The invention concerns: —a silylated biomolecule having the following formula (I): —the process for the preparation of a silylated biomolecule of formula (I), —the use of a silylated biomolecule of formula (I) to functionalize the surface of a support, —a process for the preparation of a hydrogel by use of a silylated biomolecule of formula (I), the hydrogel obtainable by said process, —said hydrogel as a biological tissue substitute, —a composition comprising said hydrogel in a pharmaceutically acceptable vehicle, —said composition for the release of active principle.
摘要翻译: 本发明涉及:具有下式(I)的甲硅烷基化生物分子: - 制备式(I)的甲硅烷基化生物分子的方法, - 使用式(I)的甲硅烷基化生物分子将 支持物, - 通过使用式(I)的甲硅烷基化生物分子制备水凝胶的方法,通过所述方法可获得的水凝胶作为生物组织替代物,包含所述水凝胶在药学上可接受的载体中的组合物 , - 组合释放活性成分。
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