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公开(公告)号:US06524299B1
公开(公告)日:2003-02-25
申请号:US08838685
申请日:1997-04-09
申请人: Quang Q. Tran , Marlowe Patterson , Henry Nita , Paul C. Slaikeu
发明人: Quang Q. Tran , Marlowe Patterson , Henry Nita , Paul C. Slaikeu
IPC分类号: A61M2500
CPC分类号: A61M25/0054 , A61M25/0009 , A61M25/0125
摘要: This invention is to a minimally invasive surgical device. In particular, the invention relates to an infusion catheter which may be used in cardiovascular and endovascular procedures to deliver diagnostic, therapeutic, or vasoocclusive agents to a target site accessible through the vasculature. The device is a flow-directed infusion catheter having a variety of sections of different flexibilities with tapered junctions between those sections. The inventive catheter is directed to that target site by a flow of blood to the site.
摘要翻译: 本发明涉及一种微创外科手术装置。 特别地,本发明涉及可用于心血管和血管内程序以将诊断,治疗性或血管收容剂递送至可通过脉管系统接近的靶位点的输注导管。 该装置是具有不同灵活性的各种部分的流动性输注导管,其中这些部分之间具有锥形接头。 本发明的导管通过血液流向该部位被引导到该靶位点。
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公开(公告)号:US06299627B1
公开(公告)日:2001-10-09
申请号:US09414616
申请日:1999-10-08
IPC分类号: A61M2900
CPC分类号: A61B17/12022 , A61B17/12145 , A61B17/1215
摘要: A vaso-occlusive device having an inner coating and a water-soluble outer coating. Methods of preparing the devices are also provided.
摘要翻译: 一种具有内涂层和水溶性外涂层的血管闭塞装置。 还提供了制备装置的方法。
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公开(公告)号:US5693034A
公开(公告)日:1997-12-02
申请号:US458557
申请日:1995-06-02
申请人: Paul J. Buscemi , Paul C. Slaikeu
发明人: Paul J. Buscemi , Paul C. Slaikeu
IPC分类号: A61K9/06 , A61K47/32 , A61L29/08 , A61M25/08 , C08F2/44 , C08L33/06 , C09D4/00 , C09D133/06 , A61K9/14 , A61M25/00 , A61M25/10
CPC分类号: C08L33/06 , A61L29/085 , C09D133/06 , C08L2205/04
摘要: A polymer network useful as a lubricous coating, the polymer network comprising a reaction product of a vinyl prepolymer and an uncrosslinked hydrogel retained within the reaction product such that the network exhibits a greater lubricity when wet.
摘要翻译: 用作润滑涂层的聚合物网络,聚合物网络包含保留在反应产物内的乙烯基预聚物和未交联的水凝胶的反应产物,使得当湿润时网络表现出更大的润滑性。
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公开(公告)号:US06663607B2
公开(公告)日:2003-12-16
申请号:US09352187
申请日:1999-07-12
IPC分类号: A61M2500
CPC分类号: A61F2/82 , A61B17/12022 , A61B17/12118 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61F2/90 , A61F2002/823 , A61L31/043
摘要: This is an implantable medical device assembly for use in surgical procedures. It is most preferably an implantable structure having stenting properties but only partially coated with or partially associated with a material causing a localized angiogenic response. One variation of is an artificial occlusion kit having the inventive implantable stenting structure situatable and vaso-occlusive devices. The implantable stenting structure is typically situated so to prevent migration of artificial occlusion devices or implants from an occlusion site, such as an aneurysm, and into an adjacent body space, such as a blood vessel.
摘要翻译: 这是用于外科手术的植入式医疗装置组件。 最优选的是具有支架特性的植入式结构,但仅部分涂覆或部分地与导致局部血管生成应答的材料相关联。 一种变体是具有本发明的可植入支架结构可置换和血管闭塞装置的人造闭塞试剂盒。 植入式支架结构通常被设置为防止人工闭塞装置或植入物从诸如动脉瘤的闭塞部位移动到相邻的身体空间(例如血管)中。
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公开(公告)号:US06187024B1
公开(公告)日:2001-02-13
申请号:US09189540
申请日:1998-11-10
IPC分类号: A61M2900
CPC分类号: A61L31/16 , A61B17/12022 , A61B17/1215 , A61B17/12177 , A61L31/022 , A61L31/044 , A61L31/06 , A61L31/10 , A61L2300/418 , A61L2300/608 , A61L2400/18 , A61L2430/36 , C08L65/04 , C08L67/04
摘要: This is a medical device for forming an embolism within the vasculature of a patient. More particularly, it is a vaso-occlusion device at least partially coated with a bioactive agent, a collagenous material, or a collagenous coating optionally containing or coated with other bioactive agents. A coated vaso-occlusive device which is highly flexible is also a variation.
摘要翻译: 这是用于在患者的脉管系统内形成栓塞的医疗装置。 更具体地,其是至少部分地涂覆有生物活性剂,胶原材料或任选地含有或涂覆有其它生物活性剂的胶原涂层的血管闭塞装置。 高度灵活的涂层血管闭塞装置也是一种变体。
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公开(公告)号:US5375609A
公开(公告)日:1994-12-27
申请号:US33529
申请日:1993-03-22
申请人: Richard L. Molacek , Kenneth E. Cobian , Michael J. Ebert , Allan H. Jevne , James R. Keogh , Paul C. Slaikeu
发明人: Richard L. Molacek , Kenneth E. Cobian , Michael J. Ebert , Allan H. Jevne , James R. Keogh , Paul C. Slaikeu
摘要: The present invention provides resistance to degradation from environmental stress cracking (ESC) and metal ion induced oxidation (MIO) for implantable, flexible pacing lead insulators having a body of polyether polyurethane elastomer material. A thin layer of a second polyurethane elastomer is applied as an overcoat to the lead insulator body. The second polyurethane is more resistant to ESC and MIO than the elastomer comprising the body of the insulator. Because ESC and MIO are surface phenomina, only a thin layer of the second material is required and the mechanical properties of the base material will determine the overall mechanical properties of the lead insulator.
摘要翻译: 本发明提供对具有聚醚聚氨酯弹性体材料体的可植入,柔性起搏引线绝缘子的环境应力开裂(ESC)和金属离子诱导氧化(MIO)的降解性。 将第二聚氨酯弹性体的薄层作为外涂层施加到引线绝缘体主体。 第二聚氨酯比包含绝缘体主体的弹性体更耐ESC和MIO。 因为ESC和MIO是表面的,所以仅需要第二材料的薄层,并且基材的机械性能将决定铅绝缘体的整体机械性能。
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公开(公告)号:US06231590B1
公开(公告)日:2001-05-15
申请号:US09352188
申请日:1999-07-12
IPC分类号: A61B1700
CPC分类号: A61L31/16 , A61B17/12022 , A61B17/1215 , A61B17/12177 , A61L31/022 , A61L31/044 , A61L31/06 , A61L31/10 , A61L2300/418 , A61L2300/608 , A61L2400/18 , A61L2430/36 , C08L65/04 , C08L67/04
摘要: This is a medical device for forming an embolism within the vasculature of a patient. More particularly, it is a vaso-occlusion device at least partially coated with a bioactive agent, a collagenous material, or a collagenous coating optionally containing or coated with other bioactive agents. A highly flexible vaso-occlusive device coated with such materials also forms a variation of the invention.
摘要翻译: 这是用于在患者的脉管系统内形成栓塞的医疗装置。 更具体地,其是至少部分地涂覆有生物活性剂,胶原材料或任选地含有或涂覆有其它生物活性剂的胶原涂层的血管闭塞装置。 用这种材料涂覆的高度柔性的血管闭塞装置也形成本发明的变型。
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公开(公告)号:US6160025A
公开(公告)日:2000-12-12
申请号:US291853
申请日:1999-04-14
申请人: Paul C. Slaikeu , Sangsoo Park
发明人: Paul C. Slaikeu , Sangsoo Park
CPC分类号: A61L24/06 , A61L31/048 , A61L2430/36 , C08L29/04
摘要: This relates to a composition of matter comprising partially hydrolyzed polyvinyl acetate solutions suitable for use as embolic agent precursors. In addition, a procedure for introducing the solutions into the human body to form precipitated embolic occlusion masses is shown. Finally, a procedure for treatment of hepatic tumors using portal vein embolism is described.
摘要翻译: 这涉及包含适合用作栓塞剂前体的部分水解的聚乙酸乙烯酯溶液的物质组合物。 此外,示出了将溶液引入人体以形成沉淀栓塞阻塞块的步骤。 最后,描述了使用门静脉栓塞治疗肝肿瘤的方法。
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公开(公告)号:US5980550A
公开(公告)日:1999-11-09
申请号:US100426
申请日:1998-06-18
CPC分类号: A61B17/12022 , A61B17/12145 , A61B17/1215
摘要: A vaso-occlusive device having a bioactive inner coating and a water-soluble outer coating. Methods of preparing the devices are also provided.
摘要翻译: 一种具有生物活性内涂层和水溶性外涂层的血管闭塞装置。 还提供了制备装置的方法。
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10.
公开(公告)号:US08016852B2
公开(公告)日:2011-09-13
申请号:US10409796
申请日:2003-04-09
申请人: Hanh Ho , Kenneth W. Quan, Jr. , Clifford Teoh , Robert M. Abrams , Joseph C. Eder , Paul C. Slaikeu , Michael P. Wallace , James Barry
发明人: Hanh Ho , Kenneth W. Quan, Jr. , Clifford Teoh , Robert M. Abrams , Joseph C. Eder , Paul C. Slaikeu , Michael P. Wallace , James Barry
IPC分类号: A61M29/00
CPC分类号: A61B17/12022 , A61B17/12113 , A61B17/12145 , A61B17/1215 , A61B17/12172 , A61B17/12177 , A61B90/39 , A61B2017/00004 , A61B2017/12063 , A61F2/0077 , A61L31/044 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2430/36 , C08L67/04 , C08L65/04
摘要: A vaso-occlusive device is disclosed. The device includes a vaso-occlusive member having a coating disposed thereon. In accordance with one embodiment, the coating comprises a polyacrylic material. In accordance with another embodiment, the coating comprises a polyvinyl alcohol-based material. In accordance with other embodiments, various other materials and coatings are applied to at least a portion of a vaso-occlusive device.
摘要翻译: 公开了一种血管闭塞装置。 该装置包括其上设置有涂层的血管闭塞构件。 根据一个实施方案,涂层包含聚丙烯酸材料。 根据另一个实施方案,涂层包含聚乙烯醇基材料。 根据其他实施例,各种其它材料和涂层被应用于血管闭塞装置的至少一部分。
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