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1.发明授权Liquid reagent containing microchip and method of using the same, and packaged liquid reagent containing microchip 有权含有微芯片的液体试剂及其使用方法，以及含有微芯片的包装液体试剂公开(公告)号：US09259731B2
公开(公告)日：2016-02-16
申请号：US13744596
申请日：2013-01-18
Applicant: Rohm Co., Ltd.
Inventor： Shun Momose , Hidetaka Okada
CPC classification number: B01L3/50273 , B01L3/502723 , B01L2200/141 , B01L2200/16 , B01L2300/041 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2400/0409 , B65D75/5805 , Y10T436/25
Abstract: Provided is a liquid reagent containing microchip having a fluid circuit formed of a space inside thereof. Liquid present in the fluid circuit is transferred to a desired position in the fluid circuit by applying centrifugal force. The fluid circuit includes a reagent retaining portion for accommodating a liquid reagent. The microchip includes an air introduction path formed of a groove provided on an outer surface of the microchip and coupled to the reagent retaining portion for introducing air into the reagent retaining portion, and a sealing portion provided so as to be detachable from the microchip for sealing the air introduction path. A method of using the microchip and a packaged liquid reagent containing microchip using the microchip are also provided.
Abstract translation: 本发明提供一种含有微芯片的液体试剂，其具有由其内部的空间形成的流体回路。 通过施加离心力将存在于流体回路中的液体转移到流体回路中的期望位置。 流体回路包括用于容纳液体试剂的试剂保持部。 微芯片包括由设置在微芯片的外表面上的沟槽形成的空气引入路径，并连接到用于将空气引入试剂保持部分的试剂保持部分，以及密封部分，其设置成可从微芯片上拆下以用于密封 空气引入路径。 还提供了使用微芯片的方法和使用微芯片的包含微芯片的包装液体试剂。
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公开(公告)号：US20140314636A1
公开(公告)日：2014-10-23
申请号：US14251836
申请日：2014-04-14
Applicant: ROHM CO., LTD.
Inventor： Shun Momose , Kenji Hamachi , Naoyuki Usagawa , Xin Wang , Hiroki Takeuchi , Yuki Shiritani , Tetsuya Ooka
IPC: B01L3/00
CPC classification number: B01L3/502715 , A61B5/150022 , A61B5/150358 , A61B5/157 , B01L2200/027 , B01L2300/043 , B01L2300/045 , B01L2300/0816 , B01L2400/0406 , B01L2400/0409
Abstract: There is provided a microchip including a fluid circuit composed of a space formed inside, and causing a liquid present in the fluid circuit to move within the fluid circuit by application of centrifugal force, the microchip including: an opening provided in a surface of the microchip and connected to the fluid circuit; a lid portion for opening and closing the opening; and a specimen take-in portion provided at the lid portion or in the opening, for taking in a specimen.
Abstract translation: 提供了一种微芯片，其包括由内部形成的空间构成的流体回路，并且使存在于流体回路中的液体通过施加离心力在流体回路内移动，该微芯片包括：设置在微芯片表面的开口 并连接到流体回路; 用于打开和关闭开口的盖部分; 以及设置在盖部或开口部的试样取入部，用于吸取试样。
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公开(公告)号：US20140186214A1
公开(公告)日：2014-07-03
申请号：US14138513
申请日：2013-12-23
Applicant: Rohm Co., Ltd.
Inventor： Shun Momose
IPC: B01L3/00
CPC classification number: B01L3/502753 , B01L3/502738 , B01L3/502746 , B01L2200/0621 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688 , B01L2400/086 , B01L2400/088
Abstract: A microchip including a fluid circuit composed of a space formed inside is provided. The space includes a first space, a second space, and a space connecting portion connecting the first space and the second space, and the space connecting portion has a structure portion restraining liquid moving between the first space and the second space from moving due to wettability with respect to the space connecting portion surface.
Abstract translation: 提供了包括由内部形成的空间构成的流体回路的微芯片。 空间包括第一空间，第二空间和连接第一空间和第二空间的空间连接部分，空间连接部分具有在第一空间和第二空间之间移动的结构部分限制液体由于润湿性而移动 相对于空间连接部分表面。
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Patent Agency Ranking
4.发明申请Liquid Reagent Containing Microchip and Method of Using the Same, and Packaged Liquid Reagent Containing Microchip 有权包含Microchip的液体试剂及其使用方法以及包含Microchip的包装液体试剂公开(公告)号：US20130196442A1
公开(公告)日：2013-08-01
申请号：US13744596
申请日：2013-01-18
Applicant: ROHM CO., LTD.
Inventor： Shun Momose , Hidetaka Okada
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502723 , B01L2200/141 , B01L2200/16 , B01L2300/041 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2400/0409 , B65D75/5805 , Y10T436/25
Abstract: Provided is a liquid reagent containing microchip having a fluid circuit formed of a space inside thereof. Liquid present in the fluid circuit is transferred to a desired position in the fluid circuit by applying centrifugal force. The fluid circuit includes a reagent retaining portion for accommodating a liquid reagent. The microchip includes an air introduction path formed of a groove provided on an outer surface of the microchip and coupled to the reagent retaining portion for introducing air into the reagent retaining portion, and a sealing portion provided so as to be detachable from the microchip for sealing the air introduction path. A method of using the microchip and a packaged liquid reagent containing microchip using the microchip are also provided.
Abstract translation: 本发明提供一种含有微芯片的液体试剂，其具有由其内部的空间形成的流体回路。 通过施加离心力将存在于流体回路中的液体转移到流体回路中的期望位置。 流体回路包括用于容纳液体试剂的试剂保持部。 微芯片包括由设置在微芯片的外表面上的沟槽形成的空气引入路径，并连接到用于将空气引入试剂保持部分的试剂保持部分，以及密封部分，其设置成可从微芯片上拆下以用于密封 空气引入路径。 还提供了使用微芯片的方法和使用微芯片的包含微芯片的包装液体试剂。
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公开(公告)号：US20130195719A1
公开(公告)日：2013-08-01
申请号：US13733684
申请日：2013-01-03
Applicant: Rohm Co., Ltd.
Inventor： Shun Momose , Akinori Yokogawa , Toshihiro Mori
CPC classification number: B01L3/50273 , B01L3/5025 , B01L3/5027 , B01L2200/12 , B01L2200/16 , B01L2300/0819 , B01L2300/0829 , B01L2300/0887 , B01L2300/168 , G01N21/07 , G01N33/5002 , G01N2021/0325
Abstract: A microchip includes fluid circuits therein, formed by uniting together at least a first substrate that is a transparent substrate and a second substrate having grooves provided at the substrate surface and/or through holes penetrating in a thickness direction. The fluid circuits include a liquid reagent receptacle unit to store a liquid reagent, a quantification unit to quantify the liquid reagent or specimen, and an overflow liquid storage unit connected to the quantification unit to store the liquid reagent or specimen overflowing from the quantification unit during quantification. There is also provided a method of using the microchip.
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公开(公告)号：US09346051B2
公开(公告)日：2016-05-24
申请号：US14138513
申请日：2013-12-23
Applicant: Rohm Co., Ltd.
Inventor： Shun Momose
IPC: B01L3/00
CPC classification number: B01L3/502753 , B01L3/502738 , B01L3/502746 , B01L2200/0621 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688 , B01L2400/086 , B01L2400/088
Abstract: A microchip including a fluid circuit composed of a space formed inside is provided. The space includes a first space, a second space, and a space connecting portion connecting the first space and the second space, and the space connecting portion has a structure portion restraining liquid moving between the first space and the second space from moving due to wettability with respect to the space connecting portion surface.
Abstract translation: 提供了包括由内部形成的空间构成的流体回路的微芯片。 空间包括第一空间，第二空间和连接第一空间和第二空间的空间连接部分，空间连接部分具有在第一空间和第二空间之间移动的结构部分限制液体由于润湿性而移动 相对于空间连接部分表面。
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公开(公告)号：US09138745B2
公开(公告)日：2015-09-22
申请号：US13762522
申请日：2013-02-08
Applicant: Rohm Co., Ltd.
Inventor： Shun Momose
CPC classification number: B01L3/50273 , B01L3/502707 , B01L3/502746 , B01L3/502753 , B01L3/502761 , B01L2300/0816 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2400/0409 , B01L2400/086
Abstract: A microchip which includes a fluid circuit defined by a space formed in the microchip and migrates a liquid present in the fluid circuit to a desired position in the fluid circuit by an applied centrifugal force, and a movement path control region (a surface region where an uneven pattern is formed on an inner surface of the fluid circuit) for controlling a movement path of the fluid.
Abstract translation: 一种微芯片，其包括由形成在微芯片中的空间限定的流体回路，并且通过施加的离心力将存在于流体回路中的液体迁移到流体回路中的期望位置，以及移动路径控制区域 用于控制流体的移动路径的不均匀图案形成在流体回路的内表面上。
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公开(公告)号：US20130209329A1
公开(公告)日：2013-08-15
申请号：US13762522
申请日：2013-02-08
Applicant: Rohm Co., Ltd.
Inventor： Shun Momose
IPC: B01L3/00
CPC classification number: B01L3/50273 , B01L3/502707 , B01L3/502746 , B01L3/502753 , B01L3/502761 , B01L2300/0816 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2400/0409 , B01L2400/086
Abstract: A microchip which includes a fluid circuit defined by a space formed in the microchip and migrates a liquid present in the fluid circuit to a desired position in the fluid circuit by an applied centrifugal force, and a movement path control region (a surface region where an uneven pattern is formed on an inner surface of the fluid circuit) for controlling a movement path of the fluid.
Abstract translation: 一种微芯片，其包括由形成在微芯片中的空间限定的流体回路，并且通过施加的离心力将存在于流体回路中的液体迁移到流体回路中的期望位置，以及移动路径控制区域 用于控制流体的移动路径的不均匀图案形成在流体回路的内表面上。
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