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26 条记录 (耗时 0.088 秒)

    Novel human genes and methods of use thereof
    1.
    发明申请
    Novel human genes and methods of use thereof 审中-公开
    新型人类基因及其使用方法

    公开(公告)号：US20050214893A1

    公开(公告)日：2005-09-29

    申请号：US10968812

    申请日：2004-10-19

    申请人： Rachel Meyers ,  Rory Curtis ,  Maria Glucksmann ,  Rajasekhar Bandaru ,  Rosana Kapeller-Libermann

    发明人： Rachel Meyers ,  Rory Curtis ,  Maria Glucksmann ,  Rajasekhar Bandaru ,  Rosana Kapeller-Libermann

    IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  C12N9/02 ,  C12N9/10 ,  C12N9/48 ,  C12N9/90 ,  C12Q1/26 ,  G01N33/574

    CPC分类号： C12N9/0004 ,  A61K38/00 ,  C07K14/47 ,  C07K14/4702 ,  C07K14/705 ,  C12N9/1048 ,  C12N9/48 ,  C12N9/90 ,  G01N33/57411 ,  G01N2500/04

    摘要： The invention provides isolated nucleic acids molecules, designated 47476, 67210, 49875,46842,33201, 83378,84233,64708, 85041,84234,21617, 55562,23566,33489, and 57779 nucleic acid molecules, which encode novel human genes. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 gene has been introduced or disrupted. The invention still further provides isolated 47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 proteins, fusion proteins, antigenic peptides and anti-47476, 67210, 49875, 46842, 33201, 83378, 84233, 64708, 85041, 84234, 21617, 55562, 23566, 33489, or 57779 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新的人基因的分离的核酸分子，命名为47476,67210,49875,46842,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489和57779核酸分子。 本发明还提供反义核酸分子，包含47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,161617,55562,23566,33489或57779核酸分子的重组表达载体，宿主细胞 已经引入了表达载体的非人类转基因动物，以及引入了47476,67210,49875,4642,43708,85041,84234,16617,55562,23566,33489或57779基因的非人类转基因动物，或 中断了 本发明还进一步提供分离的47476,67210,49875,4642,33201,83378,84233,64708,85041,84234,21617,55562,23566,33489或57779号蛋白，融合蛋白，抗原肽和抗-47476,67210， 49875,4462,33201,83378,84233,66708,85041,84234,21617,55562,253566,33489或57779抗体。 还提供了利用本发明组合物的诊断方法。

    Novel human membrane-associated protein and cell surface protein family members
    2.
    发明申请
    Novel human membrane-associated protein and cell surface protein family members 审中-公开
    新型人膜相关蛋白和细胞表面蛋白家族成员

    公开(公告)号：US20050019838A1

    公开(公告)日：2005-01-27

    申请号：US10860779

    申请日：2004-06-03

    申请人： Rachel Meyers ,  Maria Glucksmann ,  Rory Curtis ,  Rosana Kapeller-Libermann ,  Rajasekhar Bandaru ,  Kevin Leiby

    发明人： Rachel Meyers ,  Maria Glucksmann ,  Rory Curtis ,  Rosana Kapeller-Libermann ,  Rajasekhar Bandaru ,  Kevin Leiby

    IPC分类号： A61K38/00 ,  C07K14/47 ,  C07K14/705 ,  G01N33/53 ,  C07H21/04 ,  G01N33/567

    CPC分类号： C07K14/47 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  C07K14/705 ,  C07K14/70596 ,  C07K2319/00

    摘要： The invention provides isolated nucleic acids molecules, designated 16051a, 16051b, 58199, 57805, 56739, 39362, and 23228 nucleic acid molecules, which encode novel human membrane-associated protein family members, and human cell surface protein family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 16051a, 16051b, 58199, 57805, 56739, 39362, or 23228 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 16051a, 16051b, 58199, 57805, 56739, 39362, or 23228 gene has been introduced or disrupted. The invention still further provides isolated 16051a, 16051b, 58199, 57805, 56739, 39362, or 23228 proteins, fusion proteins, antigenic peptides and anti-16051a, 16051b, 58199, 57805, 56739, 39362, or 23228 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供了编码新的人膜相关蛋白家族成员和人类细胞表面蛋白家族成员的分离的核酸分子，命名为16051a，16051b，58199,57805,56739,39362和23228核酸分子。 本发明还提供反义核酸分子，含有16051a，16051b，58199,57805,56739,39362或23228核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及非人类转基因动物，其中16051a ，16051b，58199,57805,56739,39362或23228基因被引入或破坏。 本发明还进一步提供分离的16051a，16051b，58199,57805,56739,39362或23228蛋白，融合蛋白，抗原肽和抗-16051a，16051b，58199,57805,56739,39362或23228抗体。 还提供了利用本发明组合物的诊断方法。

    Novel human protein kinase, phosphatase, and protease family members and uses thereof
    4.
    发明申请
    Novel human protein kinase, phosphatase, and protease family members and uses thereof 失效
    新型人蛋白激酶，磷酸酶和蛋白酶家族成员及其用途

    公开(公告)号：US20070099274A1

    公开(公告)日：2007-05-03

    申请号：US11636948

    申请日：2006-12-11

    申请人： Rachel Meyers ,  Peter Olandt ,  Rosana Kapeller-Libermann ,  Rory Curtis ,  Mark Williamson ,  Nadine Weich

    发明人： Rachel Meyers ,  Peter Olandt ,  Rosana Kapeller-Libermann ,  Rory Curtis ,  Mark Williamson ,  Nadine Weich

    IPC分类号： C12P21/06 ,  C12N9/12 ,  C12N9/16 ,  C12N9/64 ,  C07H21/04

    CPC分类号： C12N9/1205 ,  A61K38/00 ,  C07K16/40 ,  C12N9/12 ,  C12N9/16 ,  C12N9/48 ,  C12N9/6424 ,  C12N9/6427 ,  C12N9/6472 ,  C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/136 ,  C12Q2600/156

    摘要： The invention provides isolated nucleic acids molecules, designated 53070, 15985, 26583, 21953, m32404, 14089, and 23436 nucleic acid molecules, which encode novel human protein kinase family members, serine/threonine protein kinase family members, serine/threonine phosphatase family members, prolyl oligopeptidase family members, trypsin family members, trypsin serine protease family members, and ubiquitin protease family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 53070, 15985, 26583, 21953, m32404, 14089, or 23436 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 53070, 15985, 26583, 21953, m32404, 14089, or 23436 gene has been introduced or disrupted. The invention still further provides isolated 53070, 15985, 26583, 21953, m32404, 14089, or 23436 proteins, fusion proteins, antigenic peptides and anti-53070, 15985, 26583, 21953, m32404, 14089, or 23436 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供分离的核酸分子，命名为53070,15985,26583,21953，m32404,14089和23436核酸分子，其编码新的人蛋白激酶家族成员，丝氨酸/苏氨酸蛋白激酶家族成员，丝氨酸/苏氨酸磷酸酶家族成员 ，脯氨酰寡肽酶家族成员，胰蛋白酶家族成员，胰蛋白酶丝氨酸蛋白酶家族成员和泛素蛋白酶家族成员。 本发明还提供反义核酸分子，含有53070,15985,26583,21953，m32404,14089或23436核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及非人类转基因动物，其中53070 ，15985,26583,21953，m32404,14089或23436基因已被引入或破坏。 本发明还进一步提供了分离的53070,15985,26583,21953，m32404,14089或23436蛋白，融合蛋白，抗原肽和抗-53070,15985,26583,21953，m32404,14089或23436抗体。 还提供了利用本发明组合物的诊断方法。

    Novel human hydrolase family members and uses thereof
    8.
    发明申请
    Novel human hydrolase family members and uses thereof 审中-公开
    新型人类水解酶家族成员及其用途

    公开(公告)号：US20070048784A1

    公开(公告)日：2007-03-01

    申请号：US11591659

    申请日：2006-11-01

    申请人： Rachel Meyers ,  Maria Glucksmann ,  Rory Curtis ,  Laura Rudolph-Owen

    发明人： Rachel Meyers ,  Maria Glucksmann ,  Rory Curtis ,  Laura Rudolph-Owen

    IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12P21/06 ,  C12N9/16 ,  C07K16/40

    CPC分类号： C12Q1/6883 ,  C12N9/82 ,  C12Q2600/156 ,  C12Q2600/158

    摘要： The invention provides isolated nucleic acids molecules, designated 26443 and 46873 nucleic acid molecules, which encode novel human hydrolase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 26443 and 46873 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 26443 and 46873 gene has been introduced or disrupted. The invention still further provides isolated 26443 and 46873 proteins, fusion proteins, antigenic peptides and anti-26443 or 46873 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供编码新的人水解酶家族成员的分离的核酸分子，命名为26443和46873核酸分子。 本发明还提供了反义核酸分子，含有26443和46873核酸分子的重组表达载体，已经引入表达载体的宿主细胞，以及引入或破坏了26443和46873基因的非人类转基因动物。 本发明还进一步提供分离的26443和46873蛋白，融合蛋白，抗原肽和抗26443或46873抗体。 还提供了利用本发明组合物的诊断方法。

    Novel 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt molecules and uses therefor
    9.
    发明申请
    Novel 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt molecules and uses therefor 审中-公开
    小分子38594,57312,53659,57250,6360,49938,32146,57259,67118,67067,62092，FBH58295FL，57255和57255分子及其用途

    公开(公告)号：US20060008819A1

    公开(公告)日：2006-01-12

    申请号：US11043889

    申请日：2005-01-25

    申请人： Rory Curtis ,  Maria Glucksmann ,  Rachel Meyers

    发明人： Rory Curtis ,  Maria Glucksmann ,  Rachel Meyers

    IPC分类号： C12Q1/68 ,  C07H21/04 ,  C12P21/06 ,  C07K14/705

    CPC分类号： C12N9/16 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  A61K48/00 ,  C07K14/47 ,  C07K14/4702 ,  C07K14/705 ,  C07K2319/00 ,  C12N9/14 ,  C12N2310/3181 ,  C12N2310/351 ,  G01N2500/02 ,  G01N2500/04 ,  G01N2500/10 ,  G01N2500/20

    摘要： The invention provides isolated nucleic acids molecules, designated 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt nucleic acid molecules, which encode transporter molecules, including sugar transporters, organic anion transporters, amino acid transporters, and phospholipid transporters. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt nucleic acid molecules, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt gene has been introduced or disrupted. The invention still further provides isolated 38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt polypeptides, fusion polypeptides, antigenic peptides and anti-38594, 57312, 53659, 57250, 63760, 49938, 32146, 57259, 67118, 67067, 62092, FBH58295FL, 57255, and 57255alt antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided.

    摘要翻译： 本发明提供分离的核酸分子，命名为38594,57312,53659,57250,66360,49938,32146,57259,67118,67067,62092，FBH58295FL，57255和57255alt核酸分子，其编码转运蛋白分子，包括糖转运蛋白， 有机阴离子转运蛋白，氨基酸转运蛋白和磷脂转运蛋白。 本发明还提供反义核酸分子，含有38594,57312,53659,57250,6360,49938,32146,57259,67118,67067,62092，FBH58295FL，57255和5725589核酸分子的重组表达载体，宿主细胞 已经引入了表达载体，已经引入或破坏其中38594,57312,53659,57502,6760,49938,32146,57259,67118,67067,62092，FBH58295FL，57255和57255alt基因的非人转基因动物。 本发明还进一步提供了分离的38594,57312,53659,57250,6360,49938,32146,57259,67118,67067,62092，FBH58295FL，57255和57255alt多肽，融合多肽，抗原肽和抗-38594,57312,53659， 57250,63760,49938,32146,57259,67118,67067,62092，FBH58295FL，57255和57255alt抗体。 还提供了利用本发明组合物的诊断和治疗方法。